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Higgins M M Obstetrics and Gynaecology, University College Dublin, National Maternity Hospital, Dublin, Ireland Maternal Fetal Medicine, Mount Sinai Hospital, Toronto, - - 2014
Chorangiomas (placental haemangiomas) are rarely diagnosed antenatally but have been associated with cardiac failure and poor outcome. The aim of this study was to review cases of antenatally diagnosed placental chorangiomas within in a large tertiary level unit. Retrospective cohort study Between January 2004 and March 2013, over 67,000 infants ...
Hillman Sc S University of Birmingham, Birmingham, - - 2014
Fetoscopic laser coagulation (FLC) has been shown to improve survival and reduce neurological morbidity in twin to twin transfusion syndrome (TTTS). Varying techniques for ablation exist with "Solomonisation" being a selective laser coagulation of placental vessels (SLCPV) with the addition of a subsequent surface coagulation of the placenta between the ...
Kent Em E Perinatal Ireland Research Consortium, Dublin, - - 2014
To evaluate the significance of an abnormal cerebroplacental ratio (CPR) in twin pregnancies. In the prospective multicenter ESPRiT study, twin pregnancies underwent serial sonographic evaluation including multi-vessel Doppler studies. CPR was expressed as the ratio of the pulsatility index (PI) of the middle cerebral artery to the PI of the ...
Temple Richard R Naval Hospital Camp Lejune Family Medicine Residency, Camp Lejeune, NC, USA. Email: - - 2014
The death of a fetus late in pregnancy can be devastating. Your role: Help the mother through the physical process, conduct a postdelivery evaluation, and provide support to the grieving family.
Siddiqui Anwar Hasan AH Department of Physiology, Jawaharlal Nehru Medical College, Aligarh, - - 2014
Objective: Pregnancy brings about significant changes in respiratory function, as evidenced by alterations in lung volumes and capacities, which are attributable to the mechanical impediment caused by the growing foetus. This study was undertaken in order to identify changes in respiratory function during normal pregnancy and to determine whether such ...
Boyer Ananda A Div. of Fetal Imaging, Dept. of Obstetrics and Gynecology, Oakland University William Beaumont School of Medicine, 3601 W. 13 Mile Rd. Royal Oak, MI, USA 48073. Electronic address: - - 2014
To determine the clinical significance of amniotic fluid sludge in twin pregnancies with a short cervix. We evaluated twin pregnancies with a short cervical length that had an ultrasound between 16 and 26 weeks (n= 78). Pregnancy outcomes in those with sludge (n= 27) and those without (n=51) were compared. ...
Fox Nathan S NS Maternal Fetal Medicine Associates, PLLC, and the Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address: - - 2014
Preeclampsia and IUGR are correlated in singleton pregnancies. The objective of this study was to estimate their relationship in twin pregnancies. Cohort of 578 patients with twin pregnancies delivered by one maternal fetal medicine practice from 2005-2013. Patients with chronic hypertension, monochorionic-monoamniotic placentation, twin-twin transfusion, and major congenital anomalies were ...
Lucovnik Miha M Department of Perinatology, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, - - 2014
Abstract Objective: To examine the impact of pre-pregnancy obesity on adverse outcomes in twin compared to singleton pregnancies. Methods: Dichorionic twin gestations with maternal body mass index >30 were matched to 3 singleton controls. Both obese groups were matched (1:3) with non-obese controls. Rates of preeclampsia, gestational diabetes, cesarean section, ...
Shen Ori O Department of Radiology, Tel Aviv Medical Center, Tel Aviv, - - 2014
Molar tooth sign (MTS) is pathognomonic for Joubert syndrome (JS) and related disorders. We report a case in which MTS was suspected in an 'at risk' patient at 16 weeks' gestation by sonography and at 18 weeks by additional ultrasound. It was then confirmed at 20 weeks by MRI. A ...
Leeners Brigitte B Clinic for Reproductive Endocrinology, University Hospital - - 2014
Abstract Objective: Hypertensive diseases in pregnancy (HDP) occur in 5-8% of all pregnancies and represent one of the most important causes of maternal and fetal morbidity. Even after a normal pregnancy/delivery adaptation to parenthood is a major challenge. However, a successful adjustment is important for future family health. As pregnancy ...
Benoit Richard M RM Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, - - 2014
Clinical Problem Twin-to-twin transfusion syndrome (TTTS) increases perinatal morbidity and mortality for 10 to 15% of monochorionic (MC) gestations. Pathophysiology MC gestations are at risk due to the angioarchitecture of the shared placenta, with anastomoses of varying type, size, and quantity. TTTS results from progression of a chronic perfusion imbalance across unbalanced ...
Baschat Ahmet A AA Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, - - 2014
Twin anemia-polycythemia sequence (TAPS) is a recently described complication of monochorionic placentation characterized by discordance in hemoglobin (Hgb) levels in the absence of amniotic fluid abnormality characteristic of classical twin-twin transfusion syndrome (TTTS). The placental angioarchitecture that predisposes to TAPS consists of small diameter arteriovenous anastomoses and the absence of ...
Bergh Eric E From the Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai - - 2014
Abstract Objective: We sought to estimate the association between CL and fFN and each pathway leading to preterm birth in twin pregnancies. Methods: Cohort study of 560 patients with twin pregnancies who underwent routine serial CL and fFN screening from 22-32 weeks in one maternal fetal medicine practice from 2005-2013. ...
Williams-Wyss Olivia O University of - - 2014
Exposure to poor maternal nutrition around the time of conception results in an early prepartum activation of the fetal pituitary-adrenal axis and in increased adrenal growth and stress response after birth associated with epigenetic changes in a differentially methylated region (DMR) of adrenal IGF2/H19. We have determined the effects of ...
Figueiredo Rita Feguri RF Federal University of Mato Grosso, - - 2014
Orofacial clefts (OFCs) have complex and multifactorial etiologies. Periconceptional folic acid supplementation can significantly reduce the risk of OFC. Evaluate the role of folate and other factors in preventing OFC by analyzing the health and socio-demographic data collected from a population sample. Retrospective case-control study in which mothers with children ...
Okby Rania R Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, POB 151, 84101, Beer Sheva, Israel, - - 2014
To investigate the influence of gestational diabetes mellitus (GDM) on maternal and neonatal outcomes in twin pregnancies. A retrospective population-based study was conducted, comparing maternal and neonatal outcome in women carrying twins with and without GDM. Deliveries occurred in a tertiary medical center between the years 1988 and 2010. Multivariable ...
Springer Stephanie S Medical University of Vienna, Department of Obstetrics and Feto-maternal Medicine, Vienna, - - 2014
To evaluate the prevalence of congenital heart disease (CHD) in monochorionic (MC) twin pregnancies with and without twin-to-twin transfusion syndrome (TTTS) in an unselected cohort, which underwent pre- and postnatal echocardiography. This was a retrospective cohort study including 451 MC twin pregnancies between 2002 and 2012. Complete outcome data were ...
Galjaard Sander S Department of Development and Regeneration, KU Leuven; Department of Obstetrics and Gynecology, University Hospitals Leuven, - - 2014
Monochorionic (MC) twin pregnancies are at increased risk of adverse outcome because of the vascular anastomoses that connect the two fetal circulations. MC monoamniotic (MA) twins are at an even higher risk due to the almost universal cord entanglement and possible compression, which can cause an acute transfusion imbalance between ...
Wu Yu Y Department of Ultrasonography, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Hubei Provincial Key Laboratory of Molecular Imaging, Wuhan, - - 2014
Conjoined twins (CT) are rare with possible serious malformations in which soft tissue, bone, or some organs are joined in utero. The extent of cardiac fusion and intracardiac anatomy of CT determine the viability, natural history, and outcome of potential surgical intervention. Early prenatal diagnosis and assessment may provide a ...
Suzuki Shunji S Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, - - 2014
Abstract Objective. We examined the perinatal outcomes of twin deliveries following selective uterine fundal pressure maneuver (UFPM) during the second stage of the first twin delivery. Methods. At our institute, if non-reassuring fetal heart rate and/or maternal exhaustion were observed during the second stage of the first twin, selective UFPM ...
Svirsky R R Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, - - 2014
To evaluate the distribution of mean arterial pressure (MAP) and uterine artery Doppler pulastility index (PI) in first trimester twins with and without pre-eclampsia. 147 twins were recruited from a specialist clinic and 110 unaffected singleton pregnancies attending the same institution served as controls. MAP and Doppler PI values were ...
Puccio Giuseppe - - 2014
Twins, compared to singletons, have an increased risk of perinatal mortality and morbidity, due mainly to a higher prevalence of preterm birth and low birthweight. Intrauterine growth restriction (IUGR) is also common and can affect one or both fetuses. In some cases, however, one twin is much smaller than the ...
Chelliah Anushka M AM Wayne State University, Detroit, - - 2014
The rate of twin delivery has increased by 76% since the 1980s and is associated with risk of neonatal intensive care unit (NICU) admission. Research on twin outcomes at term is limited. Our objective was to profile twin term pregnancies at increased risk of NICU admission. The U.S. Natality database ...
Kanter Jessica R JR Emory University, Decatur, - - 2014
Monozygotic twinning, associated with increased infant morbidity and mortality, is more common after assisted reproductive technology (ART) than in the general population. Although multiple factors have been proposed as contributors, studies seeking to define causality have been underpowered or inconclusive. We evaluated trends of monozygotic twinning in ART and its ...
Pettit Kate E KE University of California, San Diego, San Diego, - - 2014
Our objective was to characterize gestational weight gain and postpartum weight retention in term twin pregnancies by body mass index (BMI) and trimester. Retrospective cohort study including all term twin pregnancies at the University of California, San Diego Medical Center 2009-2013. Adequate gestational weight gain was determined by the 2009 ...
Ngai Ivan I Montefiore Medical Center-Einstein College of Medicine, Bronx, - - 2014
The objective of this study was to compare the outcomes of twin gestations in women with class III obesity (body mass index [BMI] greater than 40 kg/m) compared with twin gestations in women with a BMI less than 40 kg/m. The records of women with twin gestations were reviewed over ...
Pettit Kate E KE University of California, San Diego, San Diego, - - 2014
Our objective was to determine whether inadequate gestational weight gain in the second trimester in twin pregnancies is associated with an increased risk of preterm birth before 32 weeks of gestation. We performed a retrospective cohort study including all viable twin pregnancies delivered at UCSD Medical Center from 2009-2013. Adequate ...
Cruz Meredith M Medical College of Wisconsin, Milwaukee, - - 2014
To compare neonate outcomes of twin pregnancies complicated by gestational diabetes mellitus (GDM) or pregestational diabetes with those of nondiabetic twin pregnancies. U.S. birth cohort period linked birth and infant death data 2006-2009 were used to conduct a retrospective cohort study on 5,454 GDM twins diagnosed by standard definitions. They ...
Lucovnik M M Department of Perinatology, Division of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, - - 2014
Objective:To investigate associations between first-trimester bleeding and perinatal outcomes.Study design:Registry-based survey of the period 2002 through 2010. Pregnancies with versus without first-trimester bleeding were compared using Student's t- and χ(2)-test. Multivariable logistic regression was used to control for potential confounders.Result:9924 singleton and 275 twin pregnancies with first-trimester bleeding, and 160 099 ...
- - 2014
The incidence of multifetal gestations in the United States has increased dramatically over the past several decades. The rate of twin births increased 76% between 1980 and 2009, from 18.9 to 33.3 per 1,000 births (). The rate of triplet and higher-order multifetal gestations increased more than 400% during the ...
Cho Jae-Hyun JH Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, - - 2014
Type 1 citrullinemia (CTLN1) is an autosomal recessive inherited metabolic disorder caused by anargininosuccinicnate synthetase deficiency. The patient was a 38-year-old Korean woman who is a carrier for CTLN1 and her first baby was diagnosed with CTLN1. Preimplantation genetic diagnosis (PGD) for CTLN1 in day 3 embryos using polymerase chain ...
Villota Vania A VA Centre for Research in Congenital Abnormalities and Rare Diseases, Icesi University, Cali, - - 2014
Congenital varicella syndrome encompasses a broad spectrum of malformations present in children of mothers who developed chickenpox during the first 20 weeks of gestation. We report a case of a monochorionic diamniotic twin pregnancy, with maternal exposure to chickenpox during the thirteenth week of gestation, which produced one symptomatic and ...
Fox Caroline E CE Fetal Medicine Centre, Birmingham Women's Foundation Trust, University of Birmingham, Birmingham, - - 2014
Introduction: Cytokine imbalance has been implicated in placental-related pathologies, i.e. recurrent miscarriage and pre-eclampsia. Such conditions are more prevalent in multiple pregnancies. Twin-to-twin transfusion syndrome (TTTS) is associated with asymmetric placental blood flow and intra-cardiac pressures. We hypothesised that cytokine expression may be aberrant in this condition and that fetoscopic ...
Knopman Jaime M JM Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address: - - 2014
To identify the incidence, risk factors, and obstetric/perinatal outcomes associated with monozygotic twins (MZTs) after IVF. Nested case-control. University-based center. The IVF cycles eventuating in pregnancy from 2000-2009. None. The MZT incidence, chorionicity/zygosity, pregnancy/neonatal outcome. Of 6,223 gestations, 131 MZTs were diagnosed (2.1% incidence; 2.0% in autologous and 2.7% in ...
Segal Nancy L NL Department of Psychology, California State University, Fullerton, CA, - - 2014
The Yorùbá of Nigeria are well known for their high twinning rate and the statues they create to commemorate deceased twins. An impressive collection of this artwork was displayed at the University of California's Fowler Museum in Los Angeles between October 13, 2013 and March 2, 2014. An overview of ...
Weber Sarah K SK Department of Obstetrics and Prenatal Medicine, University of Bonn, Sigmund-Freud Str 25, 53105, Bonn, Germany, - - 2014
Prenatal renal vein thrombosis is a rarely described diagnostic finding. The etiology is unclear in the majority of cases, although thrombophilia was found in some affected fetuses. Precise ultrasound scan can improve detection rate of neonatal thrombosis due to characteristic findings. We present the unusual case of a dichorionic twin ...
Osianlis T T Monash IVF, Clayton 3168, - - 2014
Are all twin births following single embryo transfer (SET) monozygotic? Between 1 in 10 and in 1 in 5 twins born after SET are the result of a concurrent natural conception. The twinning rate after SET is higher than following natural conception. Most studies of twins following SET have incorrectly ...
van de Mheen Lidewij L VU Medical Center Amsterdam, The Netherlands. Electronic address: - - 2014
To assess in trichorionic triplet pregnancies the effectiveness of elective reduction to twins. Nationwide retrospective cohort study. We compared time to delivery and perinatal mortality in trichorionic triplet pregnancies electively reduced to twins as compared to ongoing trichorionic triplets and primary dichorionic twins. We identified 86 women with reduced trichorionic ...
Chaveeva Petya P Harris Birthright Research Centre of Fetal Medicine, King's College Hospital, London, - - 2014
Introduction: The objective of this study was to define the optimal method and timing of intervention in twin reversed arterial perfusion (TRAP) sequence. Material and Methods: During a period of 20 years (1993-2013), we performed endoscopic laser coagulation of umbilical cord vessels or intrafetal laser in 67 pregnancies with TRAP ...
Ko Hyun-Joo - - 2014
Abstract Objective: To evaluate the perinatal outcomes and clinical factors of unsuccessful trials of labor (TOLs) in late preterm and term twin pregnancies. Methods: We enrolled 896 consecutive twin pregnancies delivered between 1999 and 2012 in a single center, which met the following inclusion criteria: a vertex first twin, live ...
Nakasuji Takashi T Division of Reproductive Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan, - - 2014
To assess the incidence of monozygotic twinning (MZT) among cases undergoing assisted reproductive technology (ART) treatment. We performed a retrospective observational study and analyzed the data of patients who were registered in the national ART registry system of Japan from January to December 2010; only the data of patients with ...
Yamashita Akiko - - 2014
Abstract Aims: The association between the planned delivery mode and adverse perinatal outcomes of monochorionic diamniotic (MCDA) twin pregnancies at ≥36 weeks' gestation was evaluated. Methods: This retrospective cohort study included uncomplicated MCDA twin pregnancies delivered after 36 weeks' gestation during a 10-year period. Cases were classified into the trial ...
Fellman Johan J Hanken School of Economics, Helsinki, - - 2014
In earlier studies, scientists have attempted to identify genetic and environmental factors affecting the rate of multiple maternities among humans. We contribute to these studies by analysing the frequencies of multiple maternities in sibships containing triplets. Use of the Hellin transformation is included in evaluation of the triplet rate. Our ...
Lee Hye Jin HJ Department of Pediatrics, Seoul National University Children's Hospital, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-769, South Korea, - - 2014
Monochorionic (MC) pregnancy in humans is usually considered to be associated only with monozygotic twinning. However, several reports have revealed that dizygotic (DZ) twins can also share a chorion during pregnancy. A chimera is defined as an organism that contains different cells derived from two or more distinct zygotes. As ...
González González Nieves L NL Departamento de Obstetricia y Ginecología, Hospital Universitario de Canarias, Tenerife, Spain. Electronic address: - - 2014
To assess the impact of twin versus singleton pregnancy on obstetric and perinatal outcomes among women with pregestational diabetes mellitus (DM). Multicenter retrospective cohort study of women with pregestational DM and twin or singleton pregnancy, conducted in Spain during 2005-2010. Each group included 63 women (type 1 DM, n=39; type ...
Kim Mi-La ML Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, - - 2014
Heterotopic cesarean scar pregnancy (CSP) usually follows assisted reproductive technologies (ART) in women who have already delivered by cesarean section. It is extremely rare: thus far, there have been only 12 individual case reports. However, over the last 20 years, the rate of cesarean delivery has increased and ART have become ...
Kobylarz Krzysztof K Chair of Anaesthesiology and Intensive Therapy, Department of Anaesthesiology and Intensive Therapy, University Children Hospital, Collegium Medicum, Jagiellonian University, Kraków, Poland. - - 2014
This paper presents a history of the treatment of conjoined twins. The first mention of this malformation comes from the Neolithic period. Conjoined twins were depicted in mythologies of ancient peoples. The present paper focuses on the theories of formation of Siamese twins and attempts at their separation. Moreover, the ...
Sala Paolo P Trainee in Obstetrics and Gynecology, Department of Obstetrics and Gynecology, IRCCS A.O.U. San Martino IST, Genoa, - - 2014
In utero fetal surgery interventions are currently considered in selected cases of congenital diaphragmatic hernia, cystic pulmonary abnormalities, amniotic band sequence, selected congenital heart abnormalities, myelomeningocele, sacrococcygeal teratoma, obstructive uropathy, and complications of twin pregnancy. Randomized controlled trials have demonstrated an advantage for open fetal surgery of myelomeningocele and for ...
Lecointre L L Fetal Medicine, CMCO-HUS, 19 Rue Louis Pasteur, 67300, Schiltigheim/Strasbourg, - - 2014
The purpose of this study was to compare laser data, complications and neonatal outcomes of pregnancies that undergo "early" (≤ 17 weeks' gestation) fetoscopic laser ablation of placental vascular anastomoses for twin-twin transfusion syndrome (TTTS) with "conventional" cases treated after 17 weeks' gestation (WG). This is a cohort study on ...
Murray S R SR Simpson Centre for Reproductive Health, Royal Infirmary Edinburgh, 47 Little France Crescent, UK. Electronic address: - - 2014
The association between assisted reproduction technologies (ART) and multiple pregnancy is well-established, with a multiple birth rate of 24% in ART pregnancies. Multiple pregnancy is associated with significantly increased maternal and perinatal morbidity and mortality, as well as increased costs to the National Health Service. Evidence relating to the obstetric ...
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