Search Results
Results 201 - 250 of 743
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Gilliam David - - 2011
Genetic factors influence adverse pregnancy outcome in both humans and animal models. Animal research reveals that both the maternal and fetal genetic profiles are important for determining the risk of physical birth defects and prenatal mortality. Using a reciprocal-cross breeding design, we investigated whether the mother's genes may be more ...
Sala P - - 2011
The aim of this study was to evaluate the prevalence and kind of congenital malformations in assisted reproductive technology (ART) pregnancies. This study included pregnancies conceived by in-vitro fertilization (IVF) or intra cytoplasmic sperm injection (ICSI), evaluated in a referral center for prenatal diagnosis between January 2008 and December 2009. ...
Joó Gábor József - - 2011
Multiple pregnancies present a special obstetric condition whose importance has increased due to the spread of assisted reproductive techniques. We have processed the fetopathological data of 43 abortions induced in mid-term gemini pregnancies, owing to malformations affecting one or both fetuses. 67.4% of the gemini pregnancies were conceived naturally and ...
Larfors Gunnar - - 2011
Although maternal haematopoiesis is characterised by rapid proliferation and immunological adjustment, leukaemia seldom occurs in pregnant women. In this case-control study we investigated pregnancy and risk of acute myeloid leukaemia (AML). 785 women with AML diagnosed in ages 15 to 50, were compared to 1576 age and sex matched controls. ...
Larson D M - - 2011
Two experiments at 2 Nebraska locations evaluated effects of heifer development system on growth and pregnancy rate. In Exp. 1, heifers (n = 270, 225 ± 2 kg) grazed winter Sandhills range (WR) or west central Nebraska corn residue (CR) with a supplement (0.45 kg/animal; 31% CP; 80 mg·animal(-1)·d(-1) monensin). ...
Nanassy Laszlo - - 2011
During spermiogenesis, human sperm undergo a dramatic reorganization of the chromatin in which canonical histones are replaced by two types of protamines, protamine 1 (P1) and protamine (P2). P1 and P2 are expressed approximately at a 1:1 ratio in healthy men. Alteration of this ratio is associated with male infertility. ...
Ortega-Deballon Pablo - - 2011
Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) can improve survival in selected patients with primary or secondary peritoneal malignancies. With the opportunity for long-term survival, questions about the impact of those procedures in fertility in women of childbearing age can be raised. An international survey was performed among all ...
Gnisci Audrey - - 2011
Our finding that creatine phosphokinase level was significantly higher in women successfully treated for ectopic pregnancy with only a single injection of methotrexate suggests that this indicator predicts this outcome.
Tomson Torbjörn - - 2011
It is well established that children exposed to antiepileptic drugs (AEDs) in utero have an increased risk of adverse pregnancy outcomes including foetal growth retardation, major congenital malformations and impaired postnatal cognitive development. However, due to the significant maternal and foetal risks associated with uncontrolled epileptic seizures, AED treatment is ...
Olson K M - - 2011
First-lactation Holstein (HH), Jersey (JJ), and crossbred cows (HJ and JH, with sire breed listed first, followed by dam breed) were observed for cumulative energy intake (CEI15) and energy used for milk production (CEL15) at wk 15 of lactation in addition to recordings of health problems and pregnancy. Cumulative energy ...
Braems Geert - - 2011
For premenopausal patients with receptor-positive early breast cancer, administration of tamoxifen for 5 years constitutes the main adjuvant endocrine therapy. During pregnancy, tamoxifen and its metabolites interact with rapidly growing and developing embryonic or fetal tissues. Information about tamoxifen and pregnancy was gathered by searching PubMed. In addition, we had ...
Vitoratos Nikolaos - - 2010
OBJECTIVE: To evaluate alterations in the concentrations of osteoprotegerin (OPG), RANKL and the OPG/RANKL ratio in pre-eclamptic women during the puerperium. STUDY DESIGN: This cross-sectional study was performed in the maternity ward of Aretaieio Hospital in Athens, Greece. Fifteen pregnant women with severe pre-eclampsia and 15 matched controls with premature ...
Wimalasundera R C - - 2010
The substantial increase in high order multiple pregnancies in the last two decades as a result of assisted reproductive techniques has necessitated the development of multifetal pregnancy reduction as a management tool to decrease fetal number and improve perinatal survival. The evidence in favour of reduction in pregnancies with more ...
Paramasivam G - - 2010
Monochorionic pregnancies present unique challenges for selective fetal reduction, as vaso-occlusive procedures are required to ablate blood flow, usually in the umbilical cord, to achieve asystole in the selected fetus. We describe a case series of 35 monochorionic pregnancies (27 twins and eight triplets) undergoing selective fetal reduction using radiofrequency ...
Combs C Andrew - - 2010
To test whether 17 alpha-hydroxyprogesterone caproate (17P) will reduce neonatal morbidity by increasing gestational age at delivery in triplet pregnancies. Double-blind, randomized clinical trial. Mothers carrying trichorionic-triamniotic triplets were randomly assigned (in a 2:1 ratio) to weekly injections of 250 mg of 17P or placebo, starting at 16-22 weeks and ...
Rothberger Sophia - - 2010
Clonidine, a centrally acting antihypertensive agent, has been used successfully in pregnancy. We sought to describe the pharmacodynamic effects of clonidine in pregnancy and the associated impact on fetal growth. A retrospective cohort study was performed. Maternal hemodynamics were measured before and after treatment. Responses to clonidine were categorized by ...
Iwamoto Hideki - - 2010
Developments in assisted reproductive technology have allowed us to decrease the numbers of transferred embryos and thereby reduce the risk of multifetal pregnancies. However, even when the numbers of transferred embryos are restricted, the incidence of monozygotic multiple pregnancies is not reduced, and can be significantly higher than normal. We ...
Ferreira Marcelo - - 2010
To describe a unique case of MZ dichorionic twins and MZ monochorionic triplets in a quintuplet gestation after intracytoplasmatic sperm injection (ICSI) and blastocyst transfer. Case report. A 24-year-old woman underwent ICSI and received two blastocysts transferred. A quintuplet gestation was established .Transvaginal ultrasonography was performed sequentially during early pregnancy. ...
Skiadas Christine C - - 2011
To determine the prevalence and the relative benefits conferred by selective and spontaneous reduction of one or more fetuses in trichorionic triamniotic triplet pregnancies on time to delivery. Retrospective cohort study. Academic medical center. IVF patients with trichorionic triamniotic triplets between January 1998 and December 2007. None. Gestational length at ...
Evans Mark I - - 2010
Multifetal pregnancy reduction (MFPR) was developed over 20 years ago to rescue higher-order multifetal pregnancies and has become a major component of improving the outcomes in infertility therapies. By definition, MFPR will always be controversial, but opinions do not follow the traditional "pro-life/pro-choice" dichotomy that has sabotaged the more generalized ...
Skiadas Christine C - - 2010
In this retrospective cohort of IVF-conceived triplets complicated by a monochorionic pair (n = 21), selective reduction of the pair to a singleton pregnancy was associated with a significantly greater likelihood of delivery at ≥34 weeks. On average, reduction of the pair was associated with 52 days longer gestation.
Machtinger Ronit - - 2011
Objective. To compare the maternal and perinatal outcome of triplet pregnancies delivered by cesarean section with those delivered vaginally and to assess whether a vaginal delivery of triplets is still acceptable among women who are interested in further births. Study design. A retrospective analysis of 73 triplet pregnancies delivered at ≥28 week ...
Little Cindy M - - 2010
This article discusses the issue of multifetal pregnancy as a result of fertility treatments. Pregnancies with multiple gestations are associated with serious infant and maternal health risks as well as psychological distress and significant financial consequences, and are a far too common consequence of infertility treatments such as assisted reproductive ...
Little Cindy M - - 2010
This article concerns the issue of multifetal reduction performed in some cases of higher order multiple gestation in order to decrease the possibility of adverse pregnancy outcomes and increase the chances of survival in the remaining fetuses. If multifetal pregnancy reduction is considered as a treatment option, it is usually ...
Chmait Ramen H - - 2010
OBJECTIVE: We sought to assess outcomes of triplets with feto-fetal transfusion syndrome (FFTS) treated with selective laser photocoagulation of communicating vessels (SLPCV). STUDY DESIGN: All twins and triplets with FFTS treated with SLPCV were analyzed. Triplets were classified as dichorionic-triamniotic (D/T) or monochorionic-triamniotic (M/T). In M/T triplets, SLPCV between FFTS ...
Tandberg A - - 2010
OBJECTIVE: To assess changes in incidence rates and outcomes of triplets over 40 years with a particular focus on the influence of assisted reproductive technology (ART). DESIGN: Population-based cohort study. SETTING: The Medical Birth Registry of Norway. POPULATION: 2.18 million pregnancies, including 448 sets of triplets and 27,575 twin pairs, ...
Yong Paul J - - 2010
BACKGROUND: Monozygotic monochorionic triplet pregnancies in which triplets share an amniotic cavity (di- or monoamniotic) are very rare. In addition to the other risks of high-order multiple pregnancy, such triplets are at risk for cord entanglement and therefore cord accident and intrauterine demise. CASE: A 32-year-old primigravid woman was found ...
Díaz-García César - - 2010
Uterine malformations and spontaneous triplet pregnancy are rare situations separately, and both are related to worse perinatal outcomes. In the 3 cases of combined triplet pregnancy and uterus didelphys previously published, at least 2 of the 3 fetuses died. Morbidity rates are also high. We report the case of a ...
Zuppa Antonio A - - 2010
Assisted reproductive technology has made great progress during the last three decades. After the initial enthusiasm, many ethical, legal and social issues related to the application of these procedures began to evolve. Multifetal pregnancy and fetal reduction, embryo cryopreservation, preimplantation genetic diagnosis, risks of birth defects and other adverse outcome ...
Rutherford Julienne N - - 2009
The primate placenta produces a wide variety of hormones throughout gestation that regulate placental function and fetal growth. One such hormone is insulin-like growth factor-II (IGF-II), a peptide implicated in cell division, differentiation, and amino acid transport. IGF-II concentrations were measured in 23 common marmoset (Callithrix jacchus) term placentas from ...
Li Yu - - 2009
OBJECTIVE: To report a dichorionic quadramniotic quadruple gestation with monochorionic triamniotic triplets after intracytoplasmic sperm injection (ICSI) treatment and transfer of two embryos. DESIGN: Case report. SETTING: Academic reproductive medicine center. PATIENT(S): A 28-year-old nulligravida who underwent first ICSI cycle. INTERVENTION(S): After 4 years of primary infertility for andrologic subfertility, ...
Echternkamp S E - - 2009
Long-term genetic selection of cattle for fraternal twins has increased the frequency of twin and triplet ovulations. In contrast, the ratio of fetal numbers to ovulation sites in pregnant females with twin (0.83) or triplet (0.73) ovulations is <1.0 and the number of calves per parturition is 1.6 and 2.0, ...
Sepulveda Waldo - - 2009
OBJECTIVE: To report our experience with the management of triplet pregnancies complicated by an acardiac fetus. METHODS: During the 5-year period from 2003 to 2008, five cases were identified. The prenatal sonographic findings, antepartum course, antenatal intervention if performed, and perinatal outcome of each case were reviewed. RESULTS: Four pregnancies ...
Battin Malcolm - - 2009
AIM: There were two aims to the study: (1) to provide local outcome data that would be useful in counselling prospective parents of triplets; and (2) to address the deficit in accurate contemporary data on neurodevelopmental outcome and neonatal morbidity for those infants weighing less than 1500 g at birth. ...
De Lia Julian E - - 2009
Information on feto-fetal transfusion syndrome (FFTS) in higher-order multifetal gestation is limited. We report outcomes of 10 triplet pregnancies treated by fetoscopic laser occlusion of the chorioangiopagous vessels (FLOC). The study period was August 1992 to August 2008. Inclusion criteria were gestational age < or =25 weeks and ultrasound confirmation ...
Xu Chenming - - 2009
OBJECTIVE: To report an unusual case of congenital cervical atresia and tubal factor infertility, achieving triplet pregnancy through transmyometrial embryo transfer (ET) resulting in the delivery of healthy twins after multifetal pregnancy reduction (MFPR). DESIGN: Case report and literature review. SETTING: University hospital. INTERVENTION(S): Controlled ovarian hyperstimulation, oocyte retrieval, in ...
Zeck Willibald - - 2009
Delayed interval delivery in twin pregnancies is an unusual occurrence, even more so in triplet pregnancies. We report on a delayed interval delivery in a dichorionic triamniotic triplet pregnancy after in vitro fertilization (IVF). Because of severe twin to twin transfusion syndrome (TTTS), two fetuses demised at 22 weeks of ...
Caritis Steve N - - 2009
To assess whether 17 alpha-hydroxyprogesterone caproate reduces the rate of preterm birth in women carrying triplets. We performed this randomized, double-blinded, placebo-controlled trial in 14 centers. Healthy women with triplets were randomly assigned to weekly intramuscular injections of either 250 mg of 17 alpha-hydroxyprogesterone caproate or matching placebo, starting at ...
Dubrey Simon William - - 2009
ARTERIOVENOUS MALFORMATION (AVM) OCCURRING IN ASSOCIATION WITH SOFT TISSUE AND SKELETAL HYPERTROPHY FORMS THE BASIS OF THE PARKES WEBER SYNDROME: a rare congenital angio-osteohypertrophy condition with no obvious racial, gender or geographic preference. Usually in the lower limbs, the AVM can result in a dilated cardiomyopathy due to a high ...
Pantos Konstas - - 2009
OBJECTIVE: To report on a patient with a quintuplet pregnancy consisting of a monochorionic triamnionic triplet pregnancy and one case of monoamniotic twins after intracytoplasmic sperm injection (ICSI), laser-assisted hatching, and day 4 embryo transfer. CASE REPORT: A 34-year-old woman who underwent ICSI due to male infertility. She underwent standard ...
Lembet Arda - - 2009
Multifetal pregnancy reduction (MFPR) offers a therapeutic option which reduces the maternal, prenatal, neonatal morbidity and mortality associated with multifetal pregnancies. In certain cases of MFPR, where difficulty is encountered in reaching the thorax due to the fetal position as well as the location of membranes and placenta, an alternative ...
Guilherme Romain - - 2009
OBJECTIVE: To assess the diagnostic accuracy and show the prognostic influence of different ultrasonographic criteria in triplet pregnancies(TP). DESIGN: Retrospective study. SETTING: Tertiary care center in France. POPULATION: Fifty-one consecutive TP in which at least one of the children, live- or stillborn, weighed 500 g or more, and with a ...
Ogueh Onome - - 2009
OBJECTIVE: To determine the sequence and extent of maternal cardiovascular adaptation in an integrated way in spontaneous and assisted conception pregnancies. METHODS: Cardiovascular assessments were performed pre-pregnancy, during pregnancy and 6 weeks post delivery in women with normal spontaneously conceived singleton pregnancies (n = 13); singleton IVF pregnancies (n = ...
Arabin Birgit - - 2009
OBJECTIVE: There are few prospective cohorts of delayed-interval delivery for twin and triplet pregnancies. Nonetheless, the procedure is an option to improve perinatal outcome. STUDY DESIGN: A standard protocol was designed before candidates for delayed interval were managed by the 2 authors from 1991 to 2007. Perinatal as maternal outcomes ...
Guilherme Romain - - 2008
We assess the prognostic values of zygosity and chorionicity in triplet pregnancies (TP) with the assistance of microsatellites analysis. 53 consecutive TP whose prenatal care and delivery occurred in our maternity hospital were included in this prospective study. Zygosity of all sets of triplets (alive or stillbirth, after 22 weeks ...
Guilherme Romain - - 2009
BACKGROUND: In studies of twin and triplet pregnancies, molecular genetic techniques have rarely been used to confirm zygosity yet this is the most accurate approach. The aim of this study was to present the cross-distribution of chorionicity and zygosity in triplet pregnancies as a function of their mode of conception ...
Stone Joanne - - 2008
OBJECTIVE: This study was undertaken to report on the outcome of multifetal pregnancy reduction in the most up-to-date largest single center experience with this procedure, and compare the outcome to the first 1000 cases performed at the same institution. STUDY DESIGN: 1000 consecutive cases of multifetal pregnancy reduction performed at ...
Suresh Seshadri - - 2008
OBJECTIVE: To assess multifetal pregnancy reduction in Indian context. METHODS: It is a retrospective descriptive study. Perinatal outcome of 92 multifetal pregnancies were retrieved from a well maintained database. Fetal reductions were carried out using standard protocol. RESULTS: There were 92 pregnancies referred for fetal reduction during the study period. ...
Evans Mark I - - 2008
PURPOSE OF REVIEW: Multifetal pregnancies have skyrocketed over the past two decades as a consequence of infertility treatments. Multifetal pregnancy reduction has lowered the complications considerably. Here, we review the historical and current literature to determine reasonable statistics upon which to counsel patients RECENT FINDINGS: Several papers in the past ...
Al-Kuran Oqba - - 2008
In vitro fertilisation has become a very common procedure in the infertility practice due to both accessibility and good success rates. Complications, however, are constant reminders that no procedure is totally safe. In this paper, we present a case of IVF pregnancy that presented with pelvic abscess, and despite two ...
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