Search Results
Results 251 - 300 of 1917
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Dirani Mohamed - - 2008
PURPOSE: To report the frequency of adult-onset myopia in a large cohort of Caucasian twins that were assessed as part of the Genes in Myopia (GEM) twin study and to quantify the genetic contribution in adult-onset myopia using the classic twin model. METHODS: All twins aged 18 years or older ...
Taylor Deborah M - - 2008
OBJECTIVE: To report the first dichorionic triamniotic triplet pregnancy discordant for trisomy 13 after in vitro fertilization (IVF) treatment with preimplantation genetic screening (PGS). DESIGN: Case report. SETTING: Private IVF center. PATIENT(S): A 40-year-old para 1+6 woman. INTERVENTION(S): IVF combined with PGS for chromosomes 13, 16, 18, 21, and 22, ...
Glinianaia S V - - 2008
BACKGROUND: The risk of congenital anomalies in twins is higher than in singletons, but it is less well reported in relation to chorionicity. The aim of this study was to describe the prevalence of congenital anomalies in twin pregnancies by chorionicity and by major subtype and compare the rates with ...
Chmait Ramen H - - 2008
PURPOSE OF REVIEW: The aim of this article is to review the prenatal diagnosis and treatment of complicated monochorionic twins, with emphasis on surgical management via operative fetoscopy. RECENT FINDINGS: Ultrasound is effective in the diagnosis and surveillance of several conditions that complicate monochorionic twins, such as twin-twin transfusion syndrome, ...
Faisel Hala - - 2008
OBJECTIVE: To assess trends in twinning over four decades using a population-based registry. DESIGN: Ecological study to conduct trend analysis of twin pregnancies in a geographically defined area over 40 years. SETTING: All pregnancies in the Cardiff and Vale of Glamorgan area of South Wales from 1965 to 2004, as ...
Huber A - - 2008
OBJECTIVE: To assess outcome after fetoscopic laser coagulation (FLC) of placental vascular anastomoses with the 30 degrees fetoscope in mid-trimester severe twin-to-twin transfusion syndrome (TTTS) with completely anterior placenta compared with the regular 0 degrees fetoscope in TTTS with other placental locations. METHODS: This was a prospective study of 176 ...
van Beijsterveldt Toos C E M - - 2008
Several studies report caesarean section (CS) to be a risk factor for childhood asthma. We used data from a large cohort of 5-year-old twins to examine the relationship between mode of birth delivery and asthma. The extent to which an infant is exposed to maternal vaginal flora may protect against ...
Gielen Marij M Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Department of Genetics and Cell Biology, Maastricht University, Maastricht, the Netherlands. - - 2008
The assessment of fetal growth is an essential component of good antenatal care, especially for twins. The aims of this study are to develop twin-specific intrauterine 'growth' charts, based on cross-sectional birthweight data, for monochorionic and dichorionic twins according to sex and parity, and to detect twins at risk for ...
Kakko Johan - - 2008
AIM: To compare the effects of fetal buprenorphine and methadone exposure during maintenance treatment of pregnant heroin dependent subjects. DESIGN AND SETTING: A population based comparison of consecutive, prospectively followed buprenorphine-exposed pregnancies in Stockholm County, Sweden, to retrospectively analyzed consecutive methadone-exposed pregnancies. PARTICIPANTS: All 47 pregnancies in 39 women with ...
Chang Yao-Lung - - 2008
OBJECTIVES: To evaluate the individual fetal weight/estimated placental weight ratios (F/P ratio) of the two fetuses in monochorionic (MC) twins with selective intrauterine growth restriction (IUGR). MATERIAL AND METHODS: MC twin with selective IUGR was defined as an estimated fetal weight below the 10th percentile in one twin of MC ...
Schmitz Thomas - - 2008
OBJECTIVES: To assess neonatal morbidity in twin pregnancy according to the planned mode of delivery. METHODS: A retrospective cohort study of 758 consecutive sets of twins born after 35 weeks of gestation with a cephalic-presenting first twin was undertaken in a level III maternity unit in which active management of ...
Onyiriuka, A N; ;
Background: The incidence of twin delivery in Nigeria may have changed, in view of the worldwide increase in the rates of twinning attributed to increasing maternal age and use of fertility therapies. Objective: To determine the current incidence of twin delivery in Benin City and document the foetal outcome in ...
Keselman Leandro - - 2008
The common management in most centers in cases of multiple pregnancies with preterm premature rupture of membranes (PPROM) before 22 weeks of gestation is termination of the pregnancy or the expectant approach. Expectant management of previable PPROM in twin pregnancies results in an increased rate of fetal and neonatal morbidity ...
Hernández Ana Rachel - - 2008
OBJECTIVE: The purpose of this study was to identify differences in antepartum uterine contraction frequency (UCF) in twin pregnancies with and without preterm labor (PTL). STUDY DESIGN: Twin gestations enrolled for outpatient surveillance with twice daily electronic uterine activity monitoring and telephonic nursing assessment, without interventional delivery were identified. Mean ...
Savvidou Makrina D - - 2008
OBJECTIVE: The objective of the study was to determine the levels of circulating endothelial progenitor cells (EPCs), which are peripheral blood mononuclear cells (PBMNCs) that contribute to vascular repair in normal pregnancy. STUDY DESIGN: The concentration of EPCs in maternal blood was measured in healthy nonpregnant women (group A, n ...
Sfakianaki Anna K - - 2008
OBJECTIVE: The objective of the study was to evaluate longitudinally the in vivo changes in myometrial thickness (MT) during gestation in patients carrying twin gestations in relation to pregnancy outcome. STUDY DESIGN: Serial abdominal ultrasounds were performed prospectively in 92 patients carrying twin gestations through each trimester. Ninety-seven patients pregnant ...
El Kateb A - - 2008
Fetal and perinatal loss rates are much higher in monochorionic than in dichorionic pregnancies. This is likely to be at least in part a consequence of chorio-angiopagus and severe early onset of twin-to-twin transfusion syndrome (TTTS). TTTS occurs in approximately 15% of all monochorionic pregnancies and is defined sonographically by ...
Detlefsen B - - 2008
BACKGROUND: Twin-to-twin transfusion syndrome (TTTS) is a rare but serious clinical constellation that occurs in up to 35 % of monochorionic twin pregnancies. In TTTS, transplacental vascular anastomosis results in a net transfusion from one twin to the other, leading to multiple postnatal complications. We report on two sets of ...
Fellman Johan - - 2008
A relationship has been proposed to exist between individual outcomes (live or stillbirth) of twins in the same set. Here, we analyze this association between live births and stillbirths among individuals in different twin pairs. When national birth registers are analyzed, individuals in opposite-sex twin sets can be identified and ...
Lee Young Mi - - 2008
OBJECTIVE: To estimate the effect of chorionicity on the risk of stillbirth in twins. METHODS: A retrospective cohort analysis was performed of all twin deliveries of at least 24 weeks of gestation at a single tertiary care center from December 2000 to May 2007. The risk of fetal death with ...
Segal Nancy L - - 2008
A brief overview of Sulloway's (1996) theory of birth order and personality is presented. A reared apart twin approach for testing his personality findings regarding openness to experience and conscientiousness in first borns and later borns is described. This is followed by summaries of three recent twin studies. The topics ...
Galy Vincent - - 2008
The cytoplasmic and nuclear compartments of animal cells mix during mitosis on disassembly of the nuclear envelope (NE). NE breakdown (NEBD) involves the dispersion of the nuclear membranes and associated proteins, including nuclear pore complexes (NPCs) and the nuclear lamina. Among the approximately 30 NPC components known, few contain transmembrane ...
Bdolah Yuval - - 2008
OBJECTIVE: Twin pregnancies are a risk factor for preeclampsia with a reported incidence of 2-3 times higher than singleton pregnancies. Soluble fms-like tyrosine kinase 1 (sFlt1), which is a circulating antiangiogenic molecule of placental origin, plays a central role in preeclampsia by antagonizing placental growth factor (PlGF) and vascular endothelial ...
Rumball C W H - - 2008
Although twins have lower birthweights than singletons, they may not experience the increased disease risk in adulthood reportedly associated with low birthweight. In contrast, another periconceptional event, maternal undernutrition, does not reduce birthweight but does affect fetal and postnatal physiology in sheep. We therefore studied maternal and fetal metabolism, growth ...
Lopriore Enrico - - 2008
AIM: Perinatal mortality and morbidity in monochorionic (MC) twins appears to be increasing compared to dichorionic (DC) twins. The aim of our study was to determine the difference in perinatal mortality and morbidity in MC and DC twins born after 37 weeks' gestation. DESIGN: A retrospective, cross-sectional study of medical ...
Spencer Kevin - - 2008
OBJECTIVE: To examine the distribution of first-trimester biochemical markers of aneuploidy in twin pregnancies, and to assess whether there are differences in the distributions between monochorionic and dichorionic twins. METHODS: Maternal serum-free beta-hCG and PAPP-A were measured between 11 + 0 and 13 + 6 weeks as part of a ...
Quarello E - - 2008
BACKGROUND: Skeletal abnormalities encompass a heterogeneous group of disorders characterized by anomalies of cartilage as well as bone growth and development. Some are lethal and express early during fetal life, making them amenable to prenatal diagnosis. The increasing use of routine ultrasonography (US) during pregnancy permits a reliable primary evaluation ...
Tung Celestine S - - 2008
BACKGROUND: Acute colonic pseudoobstruction, or Ogilvie's syndrome, is a rare but serious medical and obstetric complication. When diagnosed early, treatment with expectant management or more invasive decompression is often successful. However, if not recognized promptly or managed appropriately, this condition can be fatal. CASE: We present an unusual case of ...
Yusuf Kamran - - 2008
AIMS: Our objective was to elucidate the pathogenesis of twin discordance in four dizygotic pregnancies where only one of the twins had IUGR due to chronic villitis. METHODS: We identified four cases of dizygotic twin placentas over a period of four years with evidence of chronic villitis. There was no ...
Sokolover Nir - - 2008
We present a case of recurrent hypothermia in concordant monozygotic twins born to a mirtazapine treated mother. The twins were born at 35 weeks gestation at birth weights of 2426 g and 2355 g. Both twins presented with recurrent hypothermia continuing until day 10 of life. Possible etiologies of hypothermia ...
Stein Werner - - 2008
BACKGROUND: Following vaginal delivery of the first twin, the further management to deliver the second twin is in dispute. Controversial discussions have taken place on the importance of the time interval between the birth of the first and the second twin. OBJECTIVE: To evaluate factors influencing twin-to-twin delivery time interval, ...
Kunisaki Shaun M - - 2008
Fetal surgery has emerged from the realm of medical curiosity into an exciting, multidisciplinary specialty now capable of improving patient outcomes for a wide variety of diseases. Recent advances allow prenatal providers to both accurately diagnose and treat many fetal anomalies while maintaining maternal safety. As the initial postnatal health ...
Roberts D D Liverpool Women's NHS Foundation Trust, Crown Street, Liverpool, Merseyside, UK L8 7SS. - - 2008
Twin-twin transfusion syndrome, a condition affecting monochorionic twin pregnancies, is associated with a high risk of perinatal mortality and morbidity. A number of treatments have been introduced to treat the condition but it is unclear which intervention improves maternal and fetal outcome. The objective of this review was to evaluate ...
Buckler J M H JM Department of Paediatrics and Child Health, University of Leeds, UK. - - 2008
Twin growth studies are mostly based on pooled data without consideration of zygosity, parental heights or birth weight. The study investigated the effects of gender, zygosity, parental height and birth weight on subsequent twin growth. Height and weight measurements of 1533 twins (n = 1077 for occipito-frontal head circumference (OFC)), ...
Konda A - - 2008
OBJECTIVES: To establish a rational ritodrine therapy in relation to serum ritodrine concentration, we examined 14 twin pregnancy patients and determined their pharmacokinetic data. METHODS: We measured serum concentrations of ritodrine in twin pregnancy patients using high-performance liquid chromatography (HPLC). RESULTS: The twin pregnancy patients all exhibited linear ritodrine pharmacokinetic ...
Muñoz-Abellana B - - 2007
OBJECTIVE: To evaluate the prevalence of hypertrophic cardiomyopathy-like (HCL) changes in monochorionic twins with selective intrauterine growth restriction (sIUGR) and intermittent absent/reversed end-diastolic flow (iAREDF), also defined as Type III sIUGR, and the clinical relevance of this condition. METHODS: A total of 80 pregnancies with sIUGR were studied, 40 with, ...
Yamamoto M - - 2007
OBJECTIVE: Fetal urine production in twin-to-twin transfusion syndrome (TTTS) reflects the hemodynamic imbalance between the donor and recipient twins but it has not been measured in this particular condition. The aim of this study was to measure fetal urine production using three-dimensional (3D) ultrasound in donor and recipient twins before ...
Delbaere Ilse - - 2007
Abstract The East Flanders Prospective Twin Survey comprises data concerning placentation, mode of conception and perinatal outcome. As such, this database is convenient to study differences between spontaneous twins and twins resulting from assisted reproductive technologies (ART). Papers based on this survey demonstrated higher incidences of velamentous cord insertion, single ...
Lewi Liesbeth - - 2007
OBJECTIVE: The purpose of this study was to examine the relationship between placental territory and birthweight discordance and vascular anastomoses in monochorionic diamniotic twin placentas from pregnancies that were not complicated by twin-to-twin transfusion syndrome with 2 liveborn twins. STUDY DESIGN: Placentas originated from a prospective follow-up study of monochorionic ...
Suzuki Shunji - - 2007
Preeclampsia has been classified into two types on the basis of the T helper (Th)1/Th2 balance: Th1-predominant type and Th2 predominant type. In this study, we examined the Th1/Th2 ratio in peripheral Th cells in 11 patients with preeclamptic twin pregnancies, 11 normal (nonpreeclamptic) twin pregnancies, 11 preeclamptic singleton pregnancies, ...
Beretta E - - 2007
AIM: Twin pregnancies are at greater risk of obstetrical and perinatal adverse outcome compared to singletons. In addition, expecting twins can have particular psychological consequences on both parents. The aim of our study was to interview women with a twin pregnancy and their partners in order to assess their feelings ...
Nik Lah N A Z - - 2007
Twin reverse arterial perfusion sequence occurs in approximately one percent of monochorionic twins. This condition is always fatal for the recipient twin and carries a high mortality rate for the pump twin. Various treatment options are described, but management is continually evolving with the publication of new data. We report ...
Bensouda B - - 2007
OBJECTIVE: To determine if the discrete myocardial diastolic dysfunction documented previously in the recipient twin during the early stages of twin-twin transfusion syndrome (TTTS) has any repercussion on flow velocities through the ductus venosus (DV) and to investigate if this could allow early differentiation between TTTS and selective intrauterine growth ...
Kao Hui-Fen - - 2007
OBJECTIVE: Gastroschisis is a congenital malformation characterized by an abdominal wall defect located laterally to a normal umbilicus. The cause of gastroschisis is unknown, but most authors consider it exogenous. We describe the case of a woman with a twin pregnancy in which both twins had gastroschisis. CASE REPORT: A ...
Derom Robert - - 2007
Abstract The East Flanders Prospective Twin Survey, started in 1964, realised for the first time a population-based register of all multiple births in the Belgian Province of East Flanders, characterized by the systematic examination of the placenta and the accurate determination of zygosity based on blood groups, DNA and structure ...
Middeldorp Johanna M - - 2008
OBJECTIVES: In monoamniotic twin pregnancies discordant for fetal anomaly, parents may opt for selective feticide. However, the normal co-twin remains at risk of sudden demise from cord entanglement. We report on three cases of successful selective feticide by cord occlusion combined with cord transection. METHODS: We describe technical details and ...
Van Gaever C - - 2008
INTRODUCTION: Twin reversed arterial perfusion (TRAP) is a rare condition in monozygotic multiple gestations, caused by the formation of large arterio-arterial anastomoses. Only few serial ultrasound observations are reported, showing the delayed development in the recipient twin. CASE: A monochorionic monoamniotic twin pregnancy with discordant growth was diagnosed at 11 ...
Hack K E A - - 2008
OBJECTIVE: To evaluate mortality and morbidity in a large cohort of twin pregnancies according to chorionicity. We aimed to estimate the optimal time of delivery. DESIGN: Historical cohort design. Setting Two teaching hospitals. POPULATION: Twin pregnancies delivered in the University Medical Centre, Utrecht, and the St Elisabeth Hospital, Tilburg (1995-2004), ...
Morley Ruth - - 2007
There is evidence from singletons that maternal birthweight is positively related to offspring gestational length and birthweight, and some evidence of an inverse relationship with preterm birth. Among twins very preterm birth is the major cause of neonatal mortality and of immediate and later morbidity, including neurodevelopmental impairment. We hypothesised ...
Ahuja Niraj - - 2008
We describe the case of a 44-year-old woman admitted with mania with psychotic symptoms who presented with delusion of twin pregnancy a month after admission, which temporally correlated with hyperprolactinemia secondary to antipsychotic medication. Modification of antipsychotic medication was associated with fall in serum prolactin and disappearance of delusion of ...
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