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Beale Jennifer M A - - 2009
Herceptin (trastuzumab) is an adjuvant chemotherapy agent used in treatment of certain breast cancers. Limited information is available on the use of herceptin in pregnancy. This case is a twin pregnancy exposed to herceptin until 23 weeks' gestation. One twin had chronic renal failure develop, whereas the other twin did ...
Beksaç M Sinan - - 2010
Factor X deficiency is a rare bleeding disorder inherited in an autosomal recessive fashion. In severe cases with a definitive bleeding phenotype, prophylaxis with prothrombin complex concentrate appears to prevent bleeding very effectively. Management of factor X-deficient pregnant patients continues to be a challenge. We present a new case of ...
Suzuki Shunji - - 2010
To examine the perinatal outcomes of elderly primiparous dichorionic twin pregnancies conceived by in vitro fertilization (IVF) compared with those conceived spontaneously. Data were collected from primiparous women aged 35 and older with dichorionic twin pregnancy conceived by IVF (n = 64) and those conceived spontaneously (n = 87). Data included antenatal data, gestational ...
Fox C E - - 2009
OBJECTIVE: Twin-to-twin transfusion syndrome (TTTS) is a morbid perinatal condition associated with abnormal placentation and is treated by fetoscopic laser ablation (FLA). We assessed basal maternal serum alphafetoprotein (MSAFP) and free beta-human chorionic gonadotrophin (f-betaHCG) in uncomplicated dichorionic (DC) and monochorionic (MC) twin pregnancies and a cohort of MC twin ...
Woo Jean - - 2009
Current ultrasound techniques can accurately determine the chorionicity of twins, but not zygosity. We previously proposed that the zygosity of spontaneously conceived twins can be determined at early ultrasound, where 2 corpora lutea infers dizygosity, and 1 implies monozygosity. Here we did a case series, comparing zygosity predicted using this ...
Swende T Z - - 2009
BACKGROUND: To determine if the first twin (Twin I) weighs more than the second twin (Twin II). METHODS: One hundred and seventeen sets of twins delivered at the Federal Medical Centre Makurdi, Nigeria over a three year period between 1st January, 2005 and 31st December2007 were reviewed. RESULTS: Of the ...
Maiz Nerea - - 2009
OBJECTIVE: To examine the independent contribution of abnormal flow in the ductus venosus at 11 to 13 weeks of gestation in the prediction of adverse pregnancy outcome in relation to chorionicity. METHODS: This was a prospective study in 516 dichorionic and 179 monochorionic twin pregnancies in which the fetal ductus ...
Rauh-Hain Jose A - - 2009
OBJECTIVE: To examine the risk of developing gestational diabetes mellitus (GDM) in women with twin compared with singleton pregnancies. RESEARCH DESIGN AND METHODS: We examined a cohort of 23,056 pregnant women who gave birth to a live infant between 1 September 1998 and 31 December 2006, 553 of whom had ...
Choi Suk-Joo - - 2009
BACKGROUND: Antenatal corticosteroid (ACS) treatment is widely used for the prevention of respiratory distress syndrome (RDS) in preterm infants. However, the efficacy and safety of ACS treatment remains controversial in twin pregnancies. AIMS: To investigate the effect of ACS therapy, single or multiple courses, on the incidence of neonatal RDS ...
Inde Yusuke - - 2009
We present a case of monochorionic-diamniotic (MD) twin pregnancy with polyhydramnios-polyhydramnios sequence. A 20-year-old woman, gravida 1, para 0, was referred to our hospital at 31 weeks and 6 days' gestation for consultation about a high-risk pregnancy due to the presence of discordant fetal growth pattern (26% of fetal growth ...
Musili F - - 2009
OBJECTIVE: To review some of the aspects of multiple pregnancies. DESIGN: A retrospective review of multiple pregnancy deliveries. SETTING: Pumwani Maternity Hospital- Nairobi Kenya, between 1st January and 31st December 2006. SUBJECTS: Three hundred and twenty eight mothers with twins and two sets of triplet deliveries. RESULTS: The total annual ...
Schiesser Monika - - 2009
Maternal infection with parvovirus B19 during pregnancy can cause aplastic anemia in the fetus and may lead to nonimmune fetal hydrops and fetal demise. Twin pregnancies complicated by infection due to parvovirus B19 are very rare clinical events. We present a dichorionic, diamniotic, dizygotic twin pregnancy after in vitro fertilization ...
Turton Peter - - 2009
During a multiple pregnancy, the mother and her fetuses are exposed to a variety of risks during both pregnancy and labour. The most notable of these risks is that of pre-term labour and its associated sequelae. Whilst much research has been directed towards understanding the mechanisms of uterine contractility, very ...
Fisk N M - - 2009
Twin-twin transfusion syndrome (TTTS) is a fascinating condition in which fetuses of identical genotype adopt discordant cardiovascular phenotypes, secondary to unbalanced placental inter-twin transfusion. Flow along the primary units of inter-twin transfusion, unidirectional arteriovenous anastomoses, can be as high as litres/day each, and TTTS develops when the placenta has insufficient ...
von Wurmb-Schwark Nicole - - 2009
A 32 year-old woman was hospitalised with severe septic symptoms. The examination of the patient revealed placenta residues in the woman's uterus as cause of the infection. The police was called and investigated her apartment in search of the missing baby. Finally, the bodies of two newborn babies were found ...
Shah Anwar Ali - - 2009
The Twin Block appliance is the most commonly used functional appliance in the UK. It is very important to take a satisfactory wax bite, as it not only helps the technician to make an accurate appliance but it is essential for the successful use of this appliance. In this article, ...
Berkovitz Arie A Department of Obstetrics and Gynecology, Meir Medical Center, Kfar-Saba, - - 2010
To evaluate the risk that nulliparity poses to the outcome of twin pregnancies, an issue that gained importance due to the rise of twin gestations following assisted reproduction interventions. A prospective cohort study. Between January 1, 2004, and January 7, 2008, we prospectively enrolled all pregnancies achieved by assisted reproduction ...
McClimans Leah - - 2010
Twelve years ago the British media got wind of a London gynecologist who performed an elective reduction on a twin pregnancy reducing it to a singleton. Perhaps not surprisingly, opinion on the moral status of twin reductions was divided. But in the last few years new evidence regarding the medical ...
Moise Kenneth J KJ - - 2009
Interest in fetal intervention has become widespread in recent years. Laser therapy for the treatment of severe twin-twin transfusion alone has been the subject of more than 100 peer-reviewed articles in the past 3 years. Significant issues have arisen that affect the availability of these new therapies in the United ...
Hack Karien E - - 2009
OBJECTIVE: To study perinatal mortality and neonatal morbidity in a large cohort of monoamniotic twin pregnancies with special emphasis to the gestational age-specific mortality. METHODS: The study included monoamniotic twin pregnancies delivered in 10 perinatal centers in the Netherlands between January 2000 and December 2007. RESULTS: A total of 98 ...
Rossi A Cristina - - 2009
The aim of this study was to review literature concerning selective feticide (SF) in monochorionic pregnancies complicated with twin-twin transfusion syndrome, twin reversed arterial perfusion, severe malformation, and discordant growth. The remaining twins' outcomes were stratified for indication and surgical technique. Three hundred forty-five cases of SF were reviewed. Premature ...
Tam Teresa - - 2009
Spontaneous dizygotic unilateral twin tubal pregnancy is an extremely rare occurrence with a high risk for pregnancy-related mortality, and a diagnostic challenge for obstetricians. We present a case of a 27-year-old woman with spontaneous twin tubal pregnancy. Transvaginal color Doppler sonography revealed 2 separate gestational sacs within the right adnexa, ...
Hur Yoon-Mi - - 2009
Studies have reported that refractive errors are associated with premature births. As twins have higher prevalence of prematurity than singletons, it is important to assess similarity of the prevalence of refractive errors in twins and singletons for proper interpretations and generalizations of the findings from twin studies. We compared refractive ...
Valsecchi L - - 2009
AIM: Twin pregnancy has to be considered a risk pregnancy. One of its most controversial aspects is delivery. There is no agreement on the following topics: gestational age at term (GA), mode of delivery, use of epidural analgesia or oxytocic acceleration, impact of chorionicity and amnionicity. The aim of this ...
Chandramouly M - - 2009
TRAP (twin reversed arterial perfusion) sequence / acardiac twinning is a rare anomaly that occurs in monozygotic monochorionic twins with an incidence of 1% and in 1 in 35,000 pregnancies overall. The anomalous twin appears as a heterogeneous mass, simulating a teratoma or intrauterine fetal demise. As the normal twin ...
Treichel Markus - - 2009
BACKGROUND: Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown. METHODS: Case report and literature review. RESULTS: We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The ...
Degani S - - 2009
OBJECTIVE: To study inter-twin differences in activity during early pregnancy and to examine their relationship to subsequent infant twins' temperament. STUDY DESIGN: Measures of fetal motor activity (frequency, duration and number of movements) were collected from 26 twin pairs during ultrasound nuchal translucency scan at late first trimester and early ...
Suzuki Shunji - - 2009
OBJECTIVE: To identify the factors associated with the increased risk of developing preeclampsia in twin pregnancies compared with those in singleton pregnancies. METHODS: We reviewed the obstetric records of all deliveries at > or =22 weeks' gestation managed at the Japanese Red Cross Katsushika Maternity Hospital between 2001 and 2007. ...
Fichera A - - 2009
We report a case of monochorionic twin pregnancy complicated by twin-twin transfusion syndrome (TTTS) diagnosed in the late second trimester and treated with two amnioreductions. Three days after the first amniodrainage, the recipient twin developed intracranial ventriculomegaly and, similarly, after a few days, the donor showed signs of brain damage ...
Wong H S - - 2009
OBJECTIVE: To present and discuss the sonographic and clinical findings in one twin of a monochorionic pair affected by amyoplasia. METHODS: On ultrasound examination at 21 weeks in a monochorionic twin pregnancy, twin I was smaller, hydropic, with multiple contractures consistent with amyoplasia and oligohydramnios. Twin II was anatomically normal ...
van der Houwen Clasien - - 2009
Triploid pregnancies have an increased risk of early preeclampsia. Twin pregnancies consisting of one healthy fetus and one complete or partial molar, with or without a triploid fetus, are rare and management is complex. A 33-year-old Caucasian woman presented with a dichorionic diamniotic twin pregnancy. One fetus showed early growth ...
Bekhit M T - - 2009
BACKGROUND: Parvovirus B19 (PVB19) is a well-established cause of nonimmune hydrops fetalis and fetal anaemia in pregnancy. However, discordant viral infection of only 1 fetus in a twin pregnancy is a rare occurrence. CASE REPORT: A 40-year-old female with dichorionic, diamniotic twin pregnancy presented at 22 weeks with fetal hydrops ...
Beksaç M Sinan - - 2009
In a twin pregnancy discordant for a chromosomal or structural abnormality, the family is faced with two alternatives: expectant management or selective feticide of the abnormal fetus. Methods of selective feticide differ according to chorionicity due to the presence of intertwin anastomoses in monochorionic placentas. Intracardiac KCl injection is commonly ...
Onyiriuka Alphonsus N - - 2009
BACKGROUND: The incidence of twin delivery in Nigeria may have changed, in view of the worldwide increase in the rates of twinning attributed to increasing maternal age and use of fertility therapies. OBJECTIVE: To determine the current incidence of twin delivery in Benin City and document the foetal outcome in ...
Tihtonen K - - 2009
OBJECTIVE: To present antepartal diagnostic findings including 2D/3D ultrasonography in a rare case of conjoined twins with diamniotic placentation. METHODS: In ultrasonographic examination, a communicating structure containing solid and cystic components together with cord vessels was found between the fetuses. The long axes of the fetuses were not parallel and ...
Ishii Keisuke - - 2009
OBJECTIVES: To evaluate the prognosis of monochorionic twins with selective intrauterine growth restriction (sIUGR), classified according to the type of umbilical artery Doppler, under expectant management. METHODS: The outcome of 81 cases with isolated sIUGR was evaluated according to a classification based on umbilical artery (UA) Doppler diastolic flow in ...
Liszka Lukasz - - 2009
To the best of the authors' knowledge, no case of placental site trophoblastic tumor (PSTT) pertinent to twin pregnancy has yet been published. There are only few case reports concerning patients with PSTT who were successfully treated by fertility-sparing methods. A 29-year-old nulliparous woman was admitted to hospital in the ...
Wouters Karlijn A - - 2009
The incidence of multiple pregnancy has increased significantly in recent years as a result of assisted reproductive therapy. The most important complication of these pregnancies remains preterm delivery. We report an extraordinary case of delayed delivery after late abortion of the first twin. Tocolysis successfully prolonged the pregnancy for more ...
Suzuki Shunji - - 2009
Background. We present here 2 cases of acute twin-twin transfusion occurred during vaginal labor in monochorionic-diamniotic twin pregnancies. Case. Fetal heart rate tracings showed tachycardia in the donor twin in the first case, while they showed reassuring patterns in both twins in the second case. Conclusion. These differences in changes ...
MichaƂek Katarzyna - - 2009
The aim of this study was the clearance assessment of renal function in single- and twin-pregnant goats and a comparison of selected parameters associated with calcium-phosphate management in terms of litter size. Clearance studies were carried out on 16 pregnant Polish White Improved goats (8 single pregnancies and 8 twin ...
Alam Machado Rita De Cássia Rde - - 2009
OBJECTIVE: To evaluate early neonatal morbidity and mortality in twin pregnancies with growth discordance. DESIGN: Retrospective study. SETTING: Tertiary teaching hospital, Sao Paulo, Brazil. POPULATION: A total of 151 twin pregnancies managed and delivered at the Multiple Pregnancy Unit at Sao Paulo University Hospital between 1998 and 2004. METHODS; Comparison ...
Weghofer Andrea - - 2009
Assisted reproduction (ART) contributes to world-wide increases of twin pregnancies, in turn raising prematurity risks. Whether characteristics of ART cycles, resulting in twin gestations, can predict prematurity risks was the subject of this study. One-hundred-and-six women, ages 20 to 39 years, with consecutive dichorionic-diamniotic (DC/DA) twin gestations were retrospectively investigated. ...
Braig Ute U Department of Obstetrics, Charité Campus Virchow Klinikum, Berlin, Germany. - - 2009
We report a case of severe polycythemia in the recipient twin of a pregnancy with twin-to-twin transfusion syndrome (TTTS). Stage I TTTS was suspected at initial presentation (24 weeks) due to discordant growth associated with a twin oligo-polyhydramnios sequence. Increasing peak systolic velocity (PSV) in the middle cerebral artery (MCA) ...
Hoekstra Chantal - - 2010
OBJECTIVE: To examine differences in body composition and smoking between mothers of spontaneous monozygotic and dizygotic twins, while taking into account maternal age, gravidity, and educational attainment. DESIGN: Retrospective cohort study. SETTING: The Netherlands Twin Register. PATIENT(S): Mothers of twins (n = 19,357) registered with the Netherlands Twin Register. Data ...
Heine K - - 2008
Leflunomide is a drug used in rheumatoid arthritis with teratogenic and fetotoxic effects. Clinical data on human pregnancies are limited to a few case reports without detailed information whether the mothers did have a washout procedure as suggested by the manufacturer or what type of malformation the offspring showed. We ...
Fu Yixiao - - 2008
Twins could play a crucial role in our understanding of genetic contributions to numerous etiologically complex disorders. In China, although adult twins are relatively rare, twins will become increasingly available due to increasing twin birth rates. Thus, child twin data will be a valuable resource to contribute to the field ...
Satija Mahesh - - 2008
A retrospective study was carried out to investigate the twinning rate and its correlates from January 1991 to December 2005 in 10 villages of the Rural Health Centre, Pohir, a field practice area of the Department of Community Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India. During this study ...
Papageorghiou A T - - 2008
OBJECTIVES: To examine birth weight in dichorionic and monochorionic twins and trichorionic triplets, and to estimate the relative independent importance on growth of fetal number, chorionicity and gestational age. METHODS: Four groups of pregnancies were examined: 12,816 singleton pregnancies, 302 monochorionic twin pregnancies, 569 dichorionic twin pregnancies, and 97 trichorionic ...
Schaffer Julie V - - 2008
Aplasia cutis congenita (ACC) in a symmetric, stellate pattern on the trunk or extremities is classically associated with a fetus papyraceus. We report symmetric truncal ACC in a neonate born of a sextuplet pregnancy that had been reduced to twins. This case highlights truncal ACC as a consequence of modern ...
Hack K E A - - 2009
OBJECTIVE: To study placental characteristics in relation to perinatal outcome in 55 pairs of monochorionic monoamniotic (MA) twins. METHODS: Between January 1998 and May 2008 55 pairs of MA twins were delivered in 4 tertiary care centers and analysed for mortality, birth weight discordancy and twin-to-twin transfusion syndrome (TTTS) in ...
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