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Song Xinghua X Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin 300052, - - 2014
The present study reports a rare case of synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome in an adult male. The 42-year-old man complained of skin lesions, chest pain and lumbago. Laboratory evaluations demonstrated an elevated erythrocyte sedimentation rate and increased levels of C-reactive protein. Computerized tomography, bone scintigraphy and ...
Danielsen K K Department of Dermatology, Neuro and Orthopaedic Clinic, University Hospital of North Norway, Tromsø, Norway; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø, - - 2014
Questions remain concerning to what extent age and gender may modify the suggested association between psoriasis and the metabolic syndrome in a general population. To investigate the association between psoriasis and the metabolic syndrome within a large population-based cohort by age and gender. A cross-sectional study including 10,521 participants age ...
Tüfekçi Ozlem O Department of Pediatric Hematology, Faculty of Medicine, Dokuz Eylül University, Balcova, Izmir, - - 2014
CANDLE syndrome (chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature) is a recently described autoinflammatory syndrome characterized by early onset, recurrent fever, skin lesions, and multisystemic inflammatory manifestations. Most of the patients have been shown to have mutation in PSMB8 gene. Herein, we report a 2-year-old patient with young ...
Kluk J J Skin Tumour Unit, 2nd Floor, Block C, South Wing, St. John's Institute of Dermatology, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, United - - 2014
The development of high grade lymphoma in patients with chronic lymphocytic leukaemia is known as Richter's syndrome and is associated with a grave prognosis with a mean survival of 8 months despite treatment. Cutaneous Richter's syndrome has been described in a handful of cases and may be associated with a ...
Kozel Beth A BA Department of Pediatrics, Washington University School of Medicine, St Louis, - - 2014
Previous examination in a small number of individuals with Williams syndrome (also referred to as Williams-Beuren syndrome) has shown subtly softer skin and reduced deposition of elastin, an elastic matrix protein important in tissue recoil. No quantitative information about skin elasticity in individuals with Williams syndrome is available; nor has ...
Pirro Matteo M Unit of Internal Medicine, Angiology and Arteriosclerosis Diseases, Department of Medicine, University of Perugia, Italy - - 2014
Systemic inflammation and imbalance between endothelial injury and repair, the latter referred to as vascular incompetence, are associated with atherosclerosis and cardiovascular risk. Psoriasis, an inflammatory disease of the skin, has been associated with atherosclerosis. We investigated whether, in psoriasis, inflammation and vascular incompetence are associated with carotid intima-media thickness ...
Wall Jennifer B JB Division of Burn, Trauma, Critical Care, Department of Surgery, Brigham and Women's Hospital, Boston, MA; Division of Dermatology, Brigham and Women's Hospital, Boston, MA; Division of Plastic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA. Electronic address: - - 2014
Although chlorhexidine gluconate (CHG) disks have been shown to help reduce the incidence of central line-associated blood stream infections, their use can result in local skin necrosis. The effects of CHG disks on patients with complex skin pathology have not been studied. We report 6 cases of dermal necrosis associated ...
Dugas-Breit Susanne S Department of Dermatology, Fachklinik Hornheide, - - 2014
At the time of diagnosis primary cutaneous lymphomas are limited to the skin. T-cell lymphomas represent at least two thirds of all primary cutaneous lymphomas with mycosis fungoides and Sézary syndrome being the most frequent entities. A precise staging based on clinical, histological, immunohistological and molecular biological criteria is crucial ...
Buluş Ayşe Derya - - 2014
Abstract Iatrogenic Cushing's syndrome in children may occur as a result of the application of exogenous steroids. Prolonged use of powerful corticosteroids suppresses adrenal functions and iatrogenic Cushing's syndrome may develop particularly in infants who are given topical corticosteroids. We report here a case on three infants having Cushing's syndrome ...
Kawarai Shinpei S Veterinary Teaching Hospital Laboratory of Small Animal Clinics (S.K., N.K., H.M.), Department of Veterinary Medicine Laboratory of Veterinary Pathology (K.S.), and Laboratory of Microbiology I (A.K.), Azabu University, Sagamihara, Kanagawa, Japan; Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA (S.M.); and Central Laboratory, Japan BCG Laboratory, Kiyose, Tokyo, Japan (S.Y.). - - 2014
Cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) is a locally restricted multinodular dermatitis. Affected dogs are typically healthy, but a few show systemic signs. Herein, a case of a dog presenting with generalized ulcerative dermatitis with systemic signs of mild anemia and an increased C-reactive protein level is described. Cutaneous SPGS was ...
Handler M Z MZ Department of Dermatology, Rutgers University New Jersey Medical School, Newark, - - 2014
Staphylococcal scalded skin syndrome is a potentially life-threatening disorder caused most often by a phage group II Staphylococcus aureus infection. Staphylococcal scalded skin syndrome is more common in newborns than in adults. Staphylococcal scalded skin syndrome tends to appear abruptly with diffuse erythema and fever. The diagnosis can be confirmed by ...
Cayir Atilla - - 2014
Abstract Autoimmune polyglandular syndrome (APS) is a rarely diagnosed condition characterized by a combination of two or more organ-specific autoimmune diseases and divided into a very rare juvenile (APS type I) and a relatively common adult type (APS II-IV). The major components of APS-I are hypoparathyroidism, adrenal failure, and mucocutaneous ...
Min Sa-Hee SH Department of Veterinary Internal Medicine (Min, Kang, Park), Department of Veterinary Pathology (Sur), College of Veterinary Medicine, Konkuk University, Seoul, 143-701 South - - 2014
A 10-year-old Pekingese dog with atopic dermatitis was referred due to pyrexia, multiple skin nodules, anorexia, and depression. The dog was diagnosed as having systemic inflammatory response syndrome (SIRS) induced by bacterial dermatitis. This case presents diagnosis and treatment of SIRS with staphylococcal skin infection in a dog that was ...
Freira Sílvia S Adolescent Medicine Clinic, Department of Pediatrics, Hospital de Santa Maria, Lisbon, - - 2014
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome includes both dermatological and rheumatologic symptoms. Being a rare condition, the diagnosis is frequently late. The authors report a case of a 13-year-old boy diagnosed with synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome with unusual severe systemic repercussions. The patient presented with ...
Bakkour W W Dermatology Centre, Salford Royal NHS Foundation Trust, Manchester, - - 2014
Circinate balanitis is the commonest cutaneous manifestation of reactive arthritis (Reiter syndrome), but can also occur independently. Topical corticosteroid therapy is the most commonly used treatment, and topical calcineurin inhibitors have also been used successfully. We report a case of a 20-year-old man who presented with discrete erythematous patches with ...
Baker Mary Grace MG From the *School of Medicine, †Division of Rheumatology, Departments of Medicine, ‡Dermatology, and §Pathology and Dermatology, University of Virginia, Charlottesville, - - 2014
Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN)-like lesions in acute cutaneous lupus erythematosus [LE]) are an unusual manifestation of systemic LE. We describe a patient with widespread vesiculobullous lesions diagnosed as SJS/TEN-like acute cutaneous LE as the initial presentation of systemic LE. Stevens-Johnson syndrome/TEN-like LE may be differentiated from other vesiculobullous ...
Yang C-Y CY Clinical Pharmacy Division, Linkou Branch of Chang Gung Memorial Hospital, Taipei, - - 2014
Strontium ranelate is a relatively new medication with good safety profile for the treatment of postmenopausal osteoporosis. However, severe cutaneous adverse drug reactions have been reported, such as drug rash with eosinophilia and systemic symptoms (DRESS), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). We report the case of a ...
Bostoen J - - 2014
Increasing epidemiological evidence suggests associations between psoriasis, psoriatic arthritis (PsA) and metabolic disease. Elucidating the complex relationship between these comorbidities may have important management implications. The aim of this study was to examine the difference in prevalence of metabolic disease burden between patients with psoriasis who lack arthritic manifestations (PsO) ...
Santos Guida G Hospital Santo António dos Capuchos, Centro Hospitalar de Lisboa Central, EPE, Lisbon, - - 2014
Multiple autoimmune syndrome is a rare condition, described by Humbert and Dupond in 1988. It is defined by the association of at least 3 autoimmune diseases in the same patient. Vitiligo is the most common skin condition in this syndrome. This article presents the case of a 31-year-old male with ...
Heeren Neto Augusto Scardazan AS Programa de Pós-Gradução de Ensino e Pesquisa em Entomologia Médica e Acariologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, - - 2014
Venomous animals are those that, by means of a hunting and defense mechanism, are able to inject their prey with a toxic substance produced in their bodies, directly from specialized glands (e.g., tooth, sting, spur) through which the poison passes. Millipedes are poisonous animals; they can be harmful to humans, ...
Suman Neelam N Department of Prosthodontics, SGRD Institute of Dental Sciences and Research, Amritsar, Punjab, - - 2014
Kindler syndrome is a rare hereditary disorder, associated with skin fragility. The syndrome involves the skin and mucous membrane with radiological changes. The genetic defect has been identified on the short arm of chromosome 20. This report describes a 16-year-old patient with classical features like blistering and photosensitivity in childhood ...
Gulec Ali Ihsan AI Department of Dermatology, Duzce Medical Faculty , Duzce , - - 2014
Abstract A 27-year-old male patient presented with a maculopapular eruption on the flexural areas and buttocks after using oral ketoconazole. The patient was diagnosed with drug-induced baboon syndrome based on his history, which included prior sensitivity to topical ketoconazole, a physical examination, and histopathological findings. Baboon syndrome is a drug- ...
Rall Katharina - - 2014
Acne is a very common skin condition during adolescence and adulthood. Patients with uterovaginal agenesis (Mayer-Rokitansky-Kuster-Hauser syndrome, MRKH) treated at the Tubingen University Center for Rare Female Genital Malformations, however, clinically appeared to be less frequently affected by acne. The etiology of MRKH syndrome remains unknown. The only known MRKH-associated ...
Chandran Nisha S NS Division of Dermatology, University Medicine Cluster, National University Hospital, - - 2014
A 2-year-old girl with a diagnosis of loose anagen hair syndrome was treated with a tapering regime of minoxidil 5% solution over 28 months, resulting in quick, significant clinical improvement with no adverse effects.
Piérard Gérald E GE Laboratory of Skin Bioengineering and Imaging, Department of Clinical Sciences, University of Liège, Liège, Belgium; Department of Dermatology, University Hospital, Besançon, - - 2014
The gravitational syndrome resulting from venous pressure elevation occasionally develops on the legs during pregnancy. The limb tends to enlarge and become stiffer. The body contours are altered. To assess incipient gravitational edema due to chronic venous insufficiency using measurements of the skin tensile strength. A total of 21 women ...
Masood Sadia S Department of Medicine, Faculty Office Building, Aga Khan University Hospital, Karachi, - - 2014
Autoimmune diseases are known to have association with each other but it is very rare to see multiple autoimmune diseases in one patient. The combination of at least three autoimmune diseases in the same patient is referred to as multiple autoimmune syndrome. The case we are reporting features multiple autoimmune ...
Akoglu Gulsen G Dermatology Clinic, Ankara Halil Sivgin Cubuk State Hospital, Ankara, - - 2014
Palmoplantar erythrodysesthesia syndrome (PPES) and nail changes are common presentations of cutaneous toxicity of docetaxel chemotherapy, which deteriorate the quality of life of patients. Herein, we describe a female patient who developed PPES and multiple nail changes due to docetaxel treatment for infiltrative ductal carcinoma. Cold application and elevation of ...
Cruz-Portelles A A Critical Care Medicine Department, V. I. Lenin University General Hospital, Holguín, Cuba. Electronic address: - - 2014
Job's syndrome or Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency characterized by recurrent soft tissue infections, coarse face, skeletal and vascular abnormalities, and markedly high levels of Immunoglobulin E. Eczema that resembles atopic dermatitis but is refractory to traditional treatment and severe and recurrent bacterial pneumonias often recognized ...
Takizawa Yasunobu Y Department of Allergy and Immunological Diseases, Tokyo Metropolitan Komagome Hospital , Tokyo , - - 2014
Abstract We describe the case of a 63-year-old female who presented with severe inflammatory spondylitis, refractory to various antibiotics. Mycobacterial and fungal osteomyelitis were unlikely. Although asymptomatic, she also had osteomyelitis in the sternocostoclavicular region, and was suspected of having synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome, against which minocycline ...
Drummond Alessandra A Instituto de Dermatologia Professor Rubem David Azulay, Rio de Janeiro, - - 2014
Basal cell naevus syndrome is an inherited autosomal dominant genetic disorder characterised by multiple basal cell carcinomas (BCC), skeletal, neurological and opthalmological abnormalities. The treatment of choice of the often multiple and large BCC consists of a combined approach including surgery, liquid nitrogen and other topical treatment modalities. Imiquimod 5% ...
Konishi Tomoko T Department of Dermatology, Hyogo College of Medicine, Nishinomiya, - - 2014
Netherton syndrome (NS) is a rare autosomal recessive disorder which is caused by mutations in the SPINK5 gene encoding the serine-protease inhibitor LEKTI. Characteristic symptoms of NS include erythroderma with diffuse desquamation, hair abnormalities and atopic manifestations. Here, we report two Japanese patients with NS, one of whom had a ...
Wang Tingting T Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, - - 2014
: In 1964, Sweet described an acute febrile neutrophilic dermatosis. It is now widely accepted that Sweet syndrome is one of the associated neutrophilic dermatoses. Herein, we describe an unusual case of Sweet syndrome in a 5-year-old child who suffered from recurrent papules, plaques, and blisters on his face and ...
Greally Marie T MT National Centre for Medical Genetics, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland; Bahrain Defence Forces Hospital, Department of Paediatric Cardiology, Riffa, Kingdom of - - 2014
Through a survey of more than 20 patients with a specific subgroup of autosomal recessive congenital cutis laxa (ARCL), namely ATP6V0A2-related cutis laxa, we noted that the clinical findings on three patients included pretibial pseudo-ecchymotic skin lesions very similar to those found in classical Ehlers-Danlos syndrome. The finding is apparently ...
Akcali Cenk C Department of Dermatology, School of Medicine, Research and Trainign Hospital, Gaziantep University, Gaziantep, - - 2014
To assess clinical and laboratory parameters associated with metabolic syndrome in Turkish patients with moderate or severe plaque-type psoriasis and nonpsoriatic controls. Patients with moderate or severe plaque psoriasis (patient group) or with nonpsoriatic dermatological disease (controls) were included. Waist circumference, weight, height and arterial blood pressure were measured, together ...
Dubrey Sw S Consultant - - 2014
Patients with severe erythroderma may be misdiagnosed with erythrodermic eczema and, as in this case, psoriasis. The authors describe a case of this unusual and life-threatening condition, a cutaneous T cell lymphoma (Sézary syndrome), and the management options for this condition.
Kasparis Christos C Department of Dermatology, South Warwickshire Foundation Trust, Warwick, West Midlands, - - 2014
A 3-year-old boy was referred to the dermatology department with a 12-month history of facial erythema associated with a papular-pustular facial eruption consistent with childhood acne. He had been diagnosed with XYY syndrome identified during genetic analysis for cardiac anomalies at birth. XYY syndrome is an aneuploidy of the sex ...
Fan Zhi-Dan - - 2014
Stevens-Johnson syndrome (SJS) is a severe skin and mucosal bullous disease. When complicated with Hemophagocytic lymphohistiocytosis (HLH), the condition is especially life-threatening. Here we report the case of a 4-year-old boy suffering from SJS with extensive erythema multiforme and bulla. Despite active intervention and supportive care, the boy experienced increased ...
Almeida Hiram Larangeira de HL Jr Federal and Catholic University of Pelotas, Brazil, Associate Professor of Dermatology - Federal and Catholic University of Pelotas, - - 2014
The association of microphthalmia and linear skin defects was named microphthalmia with linear skin defects syndrome (MLS) or MIDAS syndrome (microphthalmia, dermal aplasia, and sclerocornea), an X-chromosomal disorder manifesting mainly in females. We examined a female newborn with facial linear skin defects following the Blaschko lines. Computer tomography and ophthalmological ...
Tohge Rie R Department of Neurology, Tokyo Metropolitan, Neurological Hospital, Fuchu, Tokyo, Japan Department of Neurology, Osaka Red Cross Hospital, Osaka, - - 2014
Idiopathic hypereosinophilic syndrome (IHES) is characterised by persistent eosinophilia and organ damage after ruling out other causes. IHES is clinically and pathologically heterogeneous, and several disease mechanisms have been described. Although neurological involvement with IHES is extremely rare, we report the first cases of acute myelitis with IHES, which are ...
Ben Ghorbel Imed I Department of Internal Medicine, University of Tunis El Manar, Tunis, - - 2014
A 27-year-old woman presented with persistent dryness of the mouth and eyes. She presented with permanent photodistributed rash involving the face and distal extremities. Laboratory tests showed positive Sjögren's syndrome (SS)-A and SS-B antibodies. Histological examination of minor salivary gland biopsy revealed inflammatory infiltration grade 4 according to Chisholm's classification. ...
Damevska Katerina - - 2013
Previous studies have shown a higher prevalence of metabolic syndrome in patients with psoriasis compared to controls. However, little attention has been paid to the effect of systemic anti-psoriatic drugs on the metabolic syndrome. The aim of this study was to investigate the association between psoriasis and the metabolic syndrome, ...
Rashmir-Raven Ann - - 2013
Hereditary equine regional dermal asthenia is a form of Ehlers-Danlos syndrome, and has an autosomal recessive mode of inheritance. Affected horses are typically born normal and develop lesions within the first 2 years of life. The most common symptoms of the disease include stretchy, loose skin that feels doughy or mushy. ...
Ishak Rim S - - 2013
Although the association between alopecia areata (AA), psoriasis, and other autoimmune diseases has been well reported in the literature, an association with metabolic syndrome has not been reported. We present two young women with the combination of severe psoriasis, androgen excess, metabolic syndrome, thyroiditis, and AA. Both women ultimately progressed ...
Skroza N N Department of Dermatology "Daniele Innocenzi" Sapienza University of Rome, Polo Pontino, Rome, Italy - - - 2013
Aim: Psoriasis is a systemic inflammatory immune-mediated skin disease. Recently a relationship with metabolic syndrome in terms of psoriasis severity and response to therapy was observed. Methods: We performed an open-label randomized controlled study to evaluate the role of a nutraceutical containing Q10 coenzyme, Krill-oil, lipoic acid, resveratrol, Vitis vinifera ...
Wang Yan - - 2013
To analyze the correlation between acne and Northwest dryness syndrome in the Xinjiang region to provide an epidemiological foundation for the prevention and treatment of acne in the region. The correlations among acne, clinical syndromes of Northwest dryness syndrome, and Northwest dryness syndrome were evaluated using the syndrome fitness index ...
Ardissino Gianluigi - - 2013
Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established. These cases suggest that in individuals with aHUS, when ...
Zouboulis Christos C CC Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Auenweg 38, 06847 Dessau, Germany. Electronic address: - - 2014
Acne is the most common skin disorder. In the majority of cases, acne is a disease that changes its skin distribution and severity over time; moreover, it can be a physically (scar development) and psychologically damaging condition that lasts for years. According to its clinical characteristics, it can be defined ...
M G Gopal G Professor and HOD, Department of Dermatology, Kempegowda Institute of Medical Sciences , Karnataka, India - - 2013
Background: There has been a lot of recent search on consideration of psoriasis as a systemic disease, with researchers being of the view that dermatological manifestations represent only a part of the spectrum. Although, there have been plenty of studies from the west reporting an association of psoriasis with the ...
Morice-Picard Fanny - - 2013
Costello syndrome (CS) and cardiofaciocutaneous syndrome (CFCS) are congenital disorders involving the Ras-MAPK pathway with phenotypic overlap. These two entities are thought to share common cutaneous findings, although so far they have been poorly studied. The objective of this prospective observational study was to describe the spectrum of skin findings ...
Almeida Hiram Larangeira de HL Jr Federal University of Pelotas, PelotasRS, - - 2013
We report the case of a 28-year-old woman with Kindler syndrome, a rare form of epidermolysis bullosa. Clinically, since childhood, she had widespread pigmentary changes in her skin as well as photosensitivity and fragility of the skin and mucous membranes. The mucosal involvement led to an erosive stomatitis as well ...
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