Search Results
Results 1 - 50 of 315
1 2 3 4 5 6 7 >
van den Berg Bianca B Department of Neurology, Erasmus MC University Medical Centre Rotterdam, PO Box 2040, 3000 CA Rotterdam, - - 2014
Guillain-Barré syndrome (GBS) is a potentially life-threatening postinfectious disease characterized by rapidly progressive, symmetrical weakness of the extremities. About 25% of patients develop respiratory insufficiency and many show signs of autonomic dysfunction. Diagnosis can usually be made on clinical grounds, but lumbar puncture and electrophysiological studies can help to substantiate ...
Nadeau Pierre L PL aDepartment of Cardiology bDepartment of Pathology, Institut universitaire de cardiologie et de pneumologie de Québec, Quebec City, Quebec, - - 2014
Churg-Strauss syndrome (CSS) is a rare entity that is characterized by widespread vasculitis, which affects both small and medium-sized blood vessels of nearly all organs. More than 50% of these cases have cardiac involvement, which is the major cause of morbidity and mortality. We describe a case of a patient ...
Ezeani I U IU Department of Medicine, Federal Medical Center, Umuahia, Abia State, - - 2014
Tropical diabetic hand syndrome is a term used to describe diabetes complication of the hand affecting people in the tropics. It consists of localized cellulitis with variable swelling and ulceration of the hands, progressive, fulminant hand sepsis and gangrene in extreme cases. This syndrome is not well-recognized and is therefore ...
Dieks Jana-Katharina JK Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August University Göttingen, Robert-Koch Str. 40, 37075, Göttingen, Germany, - - 2014
To date, the genetic basis of Dubowitz syndrome (short stature, microcephaly, facial abnormalities, eczema) is unknown and vascular complications are not known to be associated with this syndrome. In microcephalic osteodysplastic primordial dwarfism type II (MOPD II; disproportionate short statue, microcephaly, facial abnormalities), however, cerebral aneurysms and other vascular abnormalities ...
Lloyd Isaac E IE a University of Utah, - - 2014
Abstract Scimitar syndrome is a congenital anomaly occurring in approximately 1/50,000 births, consisting of partial anomalous pulmonary venous return, right lung hypoplasia, and several associated defects. The condition generally has significant morbidity and mortality, but the underlying cause is poorly understood. In this report, we describe two autopsy cases of ...
Plaza-Benhumea L L Departamento de Genética, Hospital para el Niño IMIEM, - - 2014
Trichorhinophalangeal syndrome type II, also known as Langer-Giedion syndrome, (TRPS II, OMIM 150230) is a contiguous gene deletion syndrome (1). Depending on the size and position of the heterozygous deleted region, the genetic defect principally involves the TRPS1, RAD21, and EXT1 genes. TRPS II,, combines the clinical features of trichorhinophalageal ...
Shalaby Tamer T Health Education Kent Surrey Sussex and Maidstone Hospital, Maidstone, UK - - 2014
Toxic shock syndrome (TSS) represents a fascinating example of immune activation caused by infection resulting in a dramatic and challenging clinical syndrome. TSS is commonly associated with tampon use and still causes significant morbidity and mortality in young healthy women. A misconception is that TSS presents with a skin rash ...
Iwasa Tadashi - - 2014
Idiopathic systemic capillary leak syndrome (ISCLS) is a rare disorder, characterized by episodic life-threatening hypotension, hypoalbuminemia, and hemoconcentration. A 10 year old girl presented with abdominal pain, vomiting, diarrhea, fever and developed generalized edema a day after admission. Clinical and laboratory findings were consistent with ISCLS. She received aggressive fluid ...
Athota Krishna P KP Department of Surgery, University of Cincinnati, Cincinnati, OH, - - 2014
In this article we propose a practical approach to the use of prone therapy for acute respiratory distress syndrome (ARDS). We have attempted to provide information to improve the understanding and implementation of prone therapy based on the literature available and our own experience. We review the basic physiology behind ...
Maitra Souvik S From the Department of Anaesthesiology and Intensive Care, All India Institute of Medical Sciences, New Delhi, India (S.M., S.B., D.K.B.); and Department of Anaesthesiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India - - 2014
Despite implementation of lung-protective ventilation strategy, acute respiratory distress syndrome is associated with significant mortality, which necessitates the evaluation of ventilatory modes other than conventional lung-protective strategy. This meta-analysis of the randomized controlled trials has been undertaken to know whether high-frequency oscillatory ventilation (HFOV) provides any mortality benefit over conventional ...
Rivière Sébastien S AP-HP, Hôpital Saint Antoine, service de Médecine Interne, Paris, F-75012, France; UPMC Université Paris 06, Faculté de Médecine Pierre et Marie Curie, Paris, F-75012, France. Electronic address: - - 2014
Current knowledge in reactive hemophagocytic syndrome mainly relies on single-centre case series including a relatively small number of patients. We aimed to identify a multicenter large cohort of adult patients with reactive hemophagocytic syndrome and to describe relevant clinical and laboratory features, underlying conditions and outcome. We conducted a multicenter ...
Li Stephanie S Penn State Hershey Heart and Vascular Institute, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey, - - 2014
We report a case of Takotsubo's syndrome in a 37-year-old woman after mitral valve repair for severe mitral regurgitation triggered by a severe protamine reaction that was likely associated with immune-mediated coronary hypersensitivity (Kounis' syndrome) and made worse by resuscitation with high doses of catecholamines. The patient recovered fully after a ...
Marraro Giuseppe A GA Healthcare Accountability Lab, Departmental Section of Legal Medicine, University of Milan, - - 2014
Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome that lacks definitive treatment. The cornerstone of management is sound intensive care treatment and early anticipatory ventilation support. A mechanical ventilation strategy aiming at optimal alveolar recruitment, judicious use of positive end-respiratory pressure (PEEP) and low tidal volumes (VT) remains the ...
Banzal Subodh S Department of Medicine, Sri Aurobindo Medical College, Indore, Madhya Pradesh, - - 2014
Autoimmune polyendocrine syndrome Type II (APS II), also known as polyglandular autoimmune syndrome Type II or Schmidt syndrome, is constellations of multiple endocrine gland insufficiencies. It is a rare, but most common of the immunoendocrinopathy syndrome. It is characterized by the obligatory occurrence of autoimmune Addison's disease in combination with ...
Thomas Mark M 1Department of Neonatal Medicine, Chelsea and Westminster Hospital NHS Foundation Trust, London, United - - 2014
Mitochondrial DNA depletion syndromes are an important cause of mitochondrial cytopathies in both children and adults. We describe a newborn with multiple congenital malformations including a right aberrant subclavian artery and a trachea-oesophageal fistula in whom mitochondrial depletion syndrome was unmasked by perioperative muscle relaxation. After vecuronium infusion, the infant ...
Osterbur K K Pittsburgh Veterinary Specialty and Emergency Center, Pittsburgh, - - 2014
Multiple organ dysfunction syndrome (MODS), defined as the presence of altered organ function in an acutely ill patient such that homeostasis cannot be maintained without intervention, is a cause of high morbidity and mortality in humans and animals. Many advances have been made in understanding the pathophysiology and treatment of ...
Kongsted Hanne - - 2014
The study evaluated the effect of New Neonatal Porcine Diarrhoea Syndrome (NNPDS) on average daily gain (ADG) and mortality and described the clinical manifestations in four herds suffering from the syndrome. NNPDS is a diarrhoeic syndrome affecting piglets within the first week of life, which is not caused by enterotoxigenic ...
Deutschman Clifford S CS Department of Anesthesiology and Critical Care and Surgery and Sepsis Research Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: - - 2014
Sepsis, a clinical syndrome occurring in patients following infection or injury, is a leading cause of morbidity and mortality worldwide. Current immunological mechanisms do not explain the basis of cellular dysfunction and organ failure, the ultimate cause of death. Here we review current dogma and argue that it is time ...
Bos Lieuwe D J LD Academic Medical Center, University of Amsterdam, Amsterdam, The - - 2014
There is a need for biological markers of the acute respiratory distress syndrome (ARDS). Exhaled breath contains hundreds of metabolites in the gas phase, some of which reflect (patho)physiological processes. We aimed to determine the diagnostic accuracy of metabolites in exhaled breath as biomarkers of ARDS.Breath from ventilated intensive care ...
Radhakrishnan Rupa R Department of Radiology, Cincinnati Children's Hospital Medical Center, MLC 5031, 3333 Burnet Ave., Cincinnati, OH, 45229-3039, - - 2014
Down syndrome, or trisomy 21, is the most common chromosomal anomaly and is characterized by intellectual disability and a typical facies. People with Down syndrome can have abnormalities of multiple organ systems. Cardiac and respiratory system involvement is the most common cause of morbidity and mortality, although every organ system ...
Cabrera-Benitez Nuria E NE From the Keenan Research Centre in Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada (N.E.C.-B., J.G.L., J.V., H.Z., A.S.S.); CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain (N.E.C.-B., J.V.); Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain (N.E.C.-B., J.V.); Departments of Anesthesia and Physiology, University of Toronto, Toronto, Ontario, Canada (J.G.L., H.Z.); Department of Medicine, Unit of Anesthesiology and Intensive Care, Medical School, University of Padua, Azienda Ospedaliera di Padova, Padua, Italy (M.P.); Department of Anesthesiology and Intensive Care Therapy, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany (P.M.S.); and Interdepartmental Division of Critical Care Medicine, Department of Medicine, University of Toronto, Toronto, Ontario, Canada (H.Z., - - 2014
One of the most challenging problems in critical care medicine is the management of patients with the acute respiratory distress syndrome. Increasing evidence from experimental and clinical studies suggests that mechanical ventilation, which is necessary for life support in patients with acute respiratory distress syndrome, can cause lung fibrosis, which ...
Reilly John P JP University of Pennsylvania, Perelman School of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine, Philadelphia, Pennsylvania, United States, University of Pennsylvania, Perelman School of Medicine, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania, United States ; - - 2014
Rationale: The acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome that can develop at various times after major trauma. Objective: To identify and characterize distinct phenotypes of ARDS after trauma based on timing of syndrome onset. Methods: Latent class analyses were used to identify patterns of ARDS onset in ...
Boyle Andrew James AJ Queen's University Belfast, Centre for Infection and Immunity , Belfast , UK - - 2014
Introduction: The acute respiratory distress syndrome (ARDS) is characterised by life-threatening respiratory failure requiring mechanical ventilation, and multiple organ failure. It has a mortality of up to 30 - 45% and causes a long-term reduction in quality of life for survivors, with only approximately 50% of survivors able to return ...
Grasso Salvatore S 1Dipartimento dell'Emergenza e Trapianti d'Organo, Sezione di Anestesiologia e Rianimazione, Università degli Studi Aldo Moro, Bari, Italy. 2Intensive Care, Ospedale Di venere, Bari, Italy. 3Dipartimento dell'Emergenza e Trapianti d'Organo, Sezione di Chirurgia Veterinaria, Università degli Studi Aldo Moro, Bari, Italy. 4Dottorato in Scienze Chirurgiche Sperimentali e Terapie Cellulari, Università degli Studi Aldo Moro, Bari, Italy. 5Center for Anesthesiology, Emergency and Intensive Care Medicine, University Medical Center Göttingen, Göttingen, Germany. 6Dipartimento di Scienze Biomediche ed Oncologia Umana, Cattedra di Statistica Medica, Università degli Studi Aldo Moro, Bari, - - 2014
The Acute Respiratory Distress Syndrome Network protocol recommends limiting tidal volume and plateau pressure; it also recommends increasing respiratory rate to prevent hypercapnia. We tested a strategy that combines the low tidal volume with lower respiratory rates and minimally invasive CO2 removal. Ten lung-damaged pigs (instilled hydrochloride). Two conditions randomly ...
Hurst Jonathan J Department of Ophthalmology, Queen's University , Kingston , - - 2014
Abstract Introduction: Orbital compartment syndrome may rarely occur in the setting of burns where therapy includes aggressive fluid resuscitation. Case: We report a case of bilateral orbital compartment syndrome in a 13-year-old male, with superficial facial burns secondary to hydrobromic acid, who did not receive aggressive fluid resuscitation. The patient ...
Luedike Peter P Division of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty Heinrich-Heine-University, University Hospital Düsseldorf, Düsseldorf, - - 2014
Early identification of acute respiratory distress syndrome (ARDS) and forceful implementation of standardized therapy algorithms are the mandatory basis of an effective therapy to improve patient outcome. Recently, a new definition of ARDS was implemented, which simplified the diagnostic criteria for ARDS. Evidence-based therapies are rare, but some cornerstone interventions ...
Khan Arif O AO Division of Pediatric Ophthalmology, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia. Electronic address: - - 2014
Early-onset severe retinal dystrophy can be isolated (Leber congenital amaurosis) or the first sign of an underlying systemic ciliopathy, such as Bardet-Biedl syndrome. Early recognition of those children with underlying systemic ciliopathy minimizes morbidity and mortality from later extraocular manifestations, the most common of which is renal disease. We report ...
Alfaifi A A - - 2014
In this paper we describe a clinical scenario of high grade fever, jaundice, hypotension and multi-organ dysfunction syndrome in a 30-year-old homeless male without radiological biliary obstruction. He was brought to our hospital by the emergency medical service of Saudi Arabia (Red Crescent) from the street. After an initial resuscitation ...
Ghonim Sarah S Specialist Registrar in - - 2014
A middle-aged women presented with severe sepsis resulting in a transient apical ballooning of the left ventricle (takotsubo syndrome).
Saxena Amrish A Department of Medicine, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha District, Maharashtra, - - 2014
Guillain-Barre syndrome (GBS) is a heterogenous group of peripheral-nerve disorders with similar clinical presentation characterized by acute, self-limited, progressive, bilateral and relatively symmetric ascending flaccid paralysis, which peaks in 2-4 weeks and then subsides. The usual complications, which occur in a patient of GBS are pneumonia, sepsis, pulmonary embolism, respiratory ...
Cornejo Rodrigo R Unidade de Terapia Intensiva, Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago, - - 2014
We report the successful treatment of two patients with aneurismal subarachnoid hemorrhage complicated by severe respiratory failure and refractory septic shock using simultaneous prone position ventilation and high-volume hemofiltration. These rescue therapies allowed the patients to overcome the critical situation without associated complications and with no detrimental effects on the ...
Ooi Yinn K YK 1 Department of Pediatrics, Division of Cardiology, Children's National Health System, The George Washington University School of Medicine, Washington, District of Columbia, United States of - - 2014
Background: Of the children with Down syndrome 40-50% have cardiac defects and the majority of these cardiac defects are amenable to biventricular repair. The outcome of single ventricle palliation is improving; nonetheless, there are limited data on Down syndrome patients with associated high-risk factors undergoing single ventricle palliation. Our aim ...
Sanz Miguel A MA University Hospital La Fe and Department of Medicine of the University of Valencia, Valencia, - - 2014
Differentiation syndrome (DS), formerly known as retinoic acid syndrome, is a relatively common and potentially severe complication seen in patients with acute promyelocytic leukemia (APL) treated with all-trans retinoic acid (ATRA) and/or arsenic trioxide (ATO). The full-blown syndrome consists of unexplained fever, weight gain, dyspnea with pulmonary infiltrates, pleuropericardial effusion, ...
Chowdhury Fazle Rabbi - - 2014
Organophosphate (OP) poisoning is the most common cause (27.64%) and has the highest death rate (13.88%) of poisoning in Bangladesh. It leads to three main syndromes notably acute cholinergic syndrome, intermediate syndrome, and delayed polyneuropathy. It rarely causes cardiac arrhythmia, pancreatitis and hepatic dysfunction. We present the case of a ...
Taupin Daniel D 1New York University School of Medicine, New York, NY. 2Department of Medicine, New York University Langone Medical Center, New York, - - 2014
Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypical case of acute respiratory distress ...
Büyükçelik Mithat M Gaziantep University Faculty of Medicine, Department of Pediatric Endocrinology and Metabolism, Gaziantep, Turkey. E-mail: - - 2014
Autoimmune polyglandular syndrome (APS) is a disorder which is associated with multiple endocrine gland insufficiency and also with non-endocrine manifestations. The pathophysiology of APS is poorly understood, but the hallmark evidence of APS is development of autoantibodies against multiple endocrine and non-endocrine organs. These autoantibodies are responsible for the dysfunction ...
Milne-Price Shauna S Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, - - 2014
On September 20, 2012, a Saudi Arabian physician reported the isolation of a novel coronavirus from a patient with pneumonia on ProMED-mail. Within a few days the same virus was detected in a Qatari patient receiving intensive care in a London hospital, a situation reminiscent of the role air travel ...
Palmer William C WC Department of Gastroenterology and Hepatology, Mayo Clinic , Jacksonville, Florida , - - 2014
Abstract Type II autoimmune polyglandular syndrome (APS), a relatively common endocrine disorder, includes primary adrenal insufficiency coupled with type 1 diabetes mellitus and/or autoimmune primary hypothyroidism. Autoimmune serositis, an associated disease, may present as symptomatic pericardial effusion. We present a case of a 54-year old male with APS who developed ...
Gupta Nishant N Nishant Gupta is an assistant professor and Dennis McGraw is an associate professor in the Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of Cincinnati, Cincinnati, Ohio. Stephen M. Kralovic is an associate professor in the Division of Infectious Diseases, Department of Internal Medicine, University of - - 2014
Lemierre syndrome is a rare and life-threatening illness. Often referred to as "the forgotten disease," its incidence is reported to be as low as 1 in a million. The microorganism responsible for Lemierre syndrome is typically Fusobacterium necrophorum. The bacterium starts in the pharynx and peritonsillar tissue, then disseminates through ...
Fettah Nurdan N From the Division of Neonatology, Dr Sami Ulus Maternity and Children Training and Research Hospital, Ankara, - - 2014
Near drowning is the term for survival after suffocation caused by submersion in water or another fluid. Pulmonary insufficiency may develop insidiously or suddenly because of near drowning. We want to present a newborn case of acute respiratory distress syndrome caused by near drowning. A 26-day-old boy was brought to ...
Dzierba Amy L - - 2014
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are conditions associated with an estimated mortality of 40–50%. The use of inhaled vasodilators can help to improve oxygenation without hemodynamic effects. This article reviews relevant studies addressing the safety and efficacy of inhaled nitric oxide (iNO) and aerosolized epoprostenol ...
Gasparović Vladimir - - 2014
Acute pancreatitis is a disease with various degrees of clinical manifestations. Mild and moderate severe acute pancreatitis is an illness characterized with chemical inflammation which, in general, passes without major complications. Clinical picture of severe acute pancreatitis other side is commonly complicated with functional deterioration of other organs, and frequently ...
Chang Youjin Y Department of Pulmonary and Critical Care Medicine, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, - - 2014
Umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) have been introduced as a possible therapy in acute lung injury and acute respiratory distress syndrome (ARDS). This case history is reported of a 59-yr-old man who was treated with MSCs in the course of ARDS and subsequent pulmonary fibrosis. He received ...
Jiří Zurek Z University Children's Hospital, Department of Anesthesia and Intensive Care, Černopolní 9, Brno 62500, Czech Republic; Masaryk University, Černopolní 9, Brno 62500, Czech Republic. Electronic address: - - 2014
Pancreatic stone protein (PSP)/regenerating protein 1-alpha (reg) is associated with inflammation, infection, and other disease-related stimuli. The prognostic value of PSP/reg among critically ill pediatric patients is unknown. The aim of this pilot study was to evaluate PSP/reg in children with systemic inflammatory response syndrome or sepsis. Prospective observational study, ...
Tonni Gabriele G Department of Obstetrics & Gynecology, Guastalla Civil Hospital, AUSL Reggio Emilia, - - 2014
Prenatal diagnosis of thanatophoric dysplasia (TD) type II presenting in the first trimester with increased nuchal translucency (NT) and cloverleaf skull (Kleeblattschaedel) have been scantly reported in the medical record. Abnormal choroid plexus has been seen in association with fetal anomalies. Here we described a case of increased NT associated ...
Assir Muhammad Zaman Khan MZ From the Department of Medicine, Allama Iqbal Medical College/Jinnah Hospital , Lahore , - - 2014
Objective: We conducted this study to review deaths due to dengue fever (DF) during a large outbreak of DF in Lahore, Pakistan. Methods: We reviewed deaths due to DF at Jinnah Hospital Lahore between August and November 2011. Clinical and laboratory data were abstracted. The 2011 World Health Organization Regional ...
Leshnower Bradley G BG Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia. Electronic address: - - 2014
Acute DeBakey type 1 aortic dissection presenting with mesenteric malperfusion is a lethal variant of all dissection-related malperfusion syndromes with reported mortality rates of 38% to 75%. Conventional surgical treatment involves proximal aortic replacement to restore true lumen perfusion, followed by mesenteric revascularization if malperfusion persists. In an attempt to ...
Huang L L Department of Internal Medicine, Ikazia Hospital Rotterdam, Rotterdam, the - - 2014
Bartter syndrome consists a group of rare autosomalrecessive renal tubulopathies characterised by renal salt wasting, hypokalaemic metabolic alkalosis, hypercalciuria and hyperreninaemic hyperaldosteronism. It is classified into five types. Mutations in the KCNJ1 gene (classified as type II) usually cause the neonatal form of Bartter syndrome. We describe an adult patient ...
Cha Yong Sung YS Department of Emergency Medicine, Wonju College of Medicine, Yonsei University, Republic of - - 2014
The myeloperoxidase index (MPXI) is elevated in infection. We ascertained whether MPXI might be useful in differentiation of sepsis versus non-infectious systemic inflammatory response syndrome (SIRS) in emergency department (ED). After exclusion of patients with an age of <18 years, trauma, haematological disease and on anticancer chemotherapy, 444 consecutive cases ...
Gargano Giancarlo G Neonatologic Unit, Obstetric and Paediatric Department, Istituto di Ricovero e Cura a Carattere Scientifico, S. Maria Nuova Hospital, Reggio Emilia, - - 2014
Fetal hydrops is a condition resulting from interstitial fluid accumulation in fetal compartments secondary to increased capillary permeability and characterized by high rates of perinatal mortality and morbidity. Clinical features include skin edema, hydrothorax, pericardial effusion, ascites with or without polyhydramnios, and placental edema. While it may occur as associated ...
1 2 3 4 5 6 7 >