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Nacif Lucas Souto LS Department of Gastroenterology, Liver and Gastrointestinal Transplant Division, University of São Paulo, São Paulo, SP, - - 2014
The hepatopulmonary syndrome has been acknowledged as an important vascular complication in lungs developing systemic hypoxemia in patients with cirrhosis and portal hypertension. Is formed by arterial oxygenation abnormalities induced from intrapulmonary vascular dilatations with liver disease. It is present in 4-32% of patients with cirrhosis. It increases mortality in ...
Savige Judy J The University of Melbourne, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia - - 2014
The glomerular filtration barrier comprises a fenestrated capillary endothelium, glomerular basement membrane and podocyte slit diaphragm. Over the past decade we have come to realise that permselectivity depends on size and not necessarily charge, that the molecular sieve depends on the podocyte contractile apparatus and is highly dynamic, and that ...
Ajayi Ebenezer Adekunle EA Department of Medicine, Ekiti State University , Ado Ekiti, Nigeria - - 2014
Abstract Background: Hypertension is an important component of metabolic syndrome, and a third of hypertensive patients have metabolic syndrome, with the common mechanistic pathway believed to be insulin resistance. It is probable that hypertensive patients with metabolic syndrome will have more severe cardiac abnormalities than those without. Similarly, electrocardiogram (ECG) ...
Ettinger Nicholas N Division of Pediatric Critical Care, Department of Pediatrics, - - 2014
In this report, the authors describe the case of a teenage boy who presented with hypertensive emergency, posterior reversible encephalopathy syndrome, and hydrocephalus due to fourth ventricle outlet obstruction. Posterior reversible encephalopathy syndrome is a well-characterized but uncommon syndrome in children that is generally triggered by severe hypertension. The unusual ...
Reeder Margo J MJ Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, - - 2014
: Pseudo-Sezary syndrome is a benign lymphoproliferative disorder, which clinically and pathologically mimics true Sezary syndrome. In this article, a case of pseudo-Sezary syndrome and review the literature has been reported. The patient was a 51-year-old man who developed erythroderma and palmoplantar keratoderma. The patient's medication history included fosinopril and ...
Goto Hirozo H Department of Kampo Medicine, Hokusei Hospital, Toyama, Japan, - - 2014
Blood stasis syndrome is one of the pathological concepts of Oriental traditional medicine. In Oriental traditional medicine, blood is thought of as not only blood but also as a living component of the body. In fact, blood stasis syndrome is related to not just circulation disorders but dermatological and gynecological ...
Hu Qiao-Xia QX Shandong University, - - 2014
The very large G protein-coupled receptor 1 (VLGR1) is a core component in inner ear hair cell development. Mutations in the vlgr1 gene cause Usher syndrome, the symptoms of which include congenital hearing loss and progressive retinitis pigmentosa. However, the mechanism of VLGR1-regulated intracellular signaling and its role in Usher ...
Wang Wei W Wei Wang, Li-Rong Zhao, Xiu-Qiang Lin, Fen Feng, Department of Gastroenterology, Foshan First People's Hospital, Foshan 520800, Guangdong Province, - - 2014
Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare brain-capillary leak syndrome, characterized by clinical symptoms of headache, visual loss, seizures and altered mental functioning. This syndrome is usually reversible and is associated with hypertension, nephropathy, and use of immunosuppressive medication and cytotoxic agents. We describe two rare cases of RPLS ...
Yang Kunqi K Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 167, Beilishi Road, Beijing 100037, - - 2014
Liddle's syndrome, an autosomal dominant form of monogenic hypertension, is characterized by salt-sensitive hypertension with early penetrance, hypokalemia, metabolic alkalosis, suppression of plasma rennin activity and aldosterone secretion, and a clear-cut response to epithelial sodium channel (ENaC) blockers but not spironolactone therapy. Our understanding of ENaCs and Na+ transport defects ...
Kawaguchi Emi E Division of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, - - 2014
Prednisolone, the first-line treatment for children with nephrotic syndrome, causes severe side effects. One of these side effects is ocular hypertension, which can result in severe and permanent visual disturbance. However, the exact prevalence, severity and timing of development of ocular hypertension have yet to be fully explored in this ...
Kim Mijin M Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea; Department of Ophthalmology, Seoul National University Hospital, Seoul, - - 2014
To determine whether normal-tension glaucoma (NTG) is associated with metabolic syndrome and to evaluate which components of metabolic syndrome are related to NTG. This study included 18240 participants who underwent health check-ups including fundus photography and intraocular pressure measurements. For NTG diagnosis, all participants with findings suggestive of glaucoma completed ...
Chen David Yen-Ting DY From the Department of Medical Imaging, Taipei Medical University, Shuang-Ho Hospital, New Taipei City, - - 2014
A 55-year-old man with chronic hypertension presented with acute headache and dizziness. Physical examination showed severe hypertension (210/140 mm Hg) without any neurologic sign. Brain MRI showed diffuse brain edema over the brainstem, bilateral thalami, and cerebellar hemispheres with multiple microbleeds at bilateral basal ganglia (figure 1). His symptoms improved ...
Fuster Valentin V Icahn School of Medicine at Mount Sinai - - 2014
An "Acute Coronary Syndrome" (ACS) is the most ominous manifestation of coronary artery disease (CAD). The burden of ACS and its impact are striking. Cardiovascular disease is now the most common cause of mortality worldwide and among cardiovascular deaths, the majority are attributable to CAD. As a result, while CAD ...
Saraf Sumit S Maimonides Medical Center, Brooklyn, - - 2014
To determine whether clinical findings among women with preeclampsia or eclampsia predict the magnetic resonance imaging (MRI) diagnosis of posterior reversible encephalopathy syndrome and to determine whether posterior reversible encephalopathy syndrome is found in all patients with eclampsia or among patients with preeclampsia. We performed a retrospective review of women ...
Chang Huai-Ren HR Divisions of Cardiology (H-RC, J-CH, MYC, J-HW) and Nephrology (B-GH), Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan; Institute of Medical Sciences (H-RC, MYC), Tzu Chi University, Hualien, Taiwan; School of Medicine (B-GH, J-HW), Tzu Chi University, Hualien, Taiwan; and Institute of Epidemiology & Preventive Medicine (L-YW), College of Public Health, National Taiwan University, Taipei, - - 2014
It has been shown that metabolic syndrome is associated with lower levels of plasma N-terminal pro-B-type natriuretic peptide (Nt-proBNP) in the general population. However, there is no study about the association between Nt-proBNP and metabolic syndrome in hypertensive patients. AIM:: To elucidate the relationship between Nt-proBNP and components of metabolic ...
Wong Ramsey Kara N KN Department of Pediatrics, University of Hawaii, Honolulu, - - 2014
There is limited information available related to the perinatal course of cardiofaciocutaneous syndrome (CFC) compared to other syndromes within the Ras-MAP kinase pathway (rasopathies) such as Noonan and Costello syndrome. Retrospective chart review revealed four cases of CFC with molecular confirmation between 2005 and 2012 at Hawaii's largest obstetric and ...
Mayer D D Clinic for Cardiovascular Surgery University Hospital of Zurich, Zurich, Switzerland - - - 2014
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are frequently encountered in patients treated for ruptured abdominal aortic aneurysms (rAAA) and carry a high morbidity and mortality risk. Despite these facts, IAH/ACS are still overlooked by many physicians, timely diagnosis is missed and treatment often inadequate. All staff involved in ...
Medina Daniel C DC 1 University of Maryland School of Medicine, Division of General and Oncologic Surgery, Baltimore, MD 21201, USA ; 2 University of Maryland Baltimore Washington Medical Center, 301 Hospital Drive, Glen Burnie, MD 21061, - - 2014
Von Hippel-Lindau is a genetic syndrome, comprising several variant mutations on chromosome 3, that predisposes patients to the development of benign and malignant tumors. Tough relatively common, Von Hippel-Lindau syndrome (VHL) with associated hepato-biliary and gastric outlet obstruction, and portal hypertension consequent to the mass effect of a pancreatic serous ...
Wu Xiaochen - - 2014
Cantrell syndrome is a rare syndrome of congenital defects, which can be complicated by severe pulmonary hypertension and left ventricular diverticulum; it has proved difficult to treat in clinical practice. A 6-month-old Han Chinese baby girl weighing 3.5kg was diagnosed, using ultrasonography and radiography, as having Cantrell syndrome complicated by ...
Said Sarmad - - 2014
Over the last decade advanced therapies for the management of pulmonary arterial hypertension have been introduced. These agents have also been effective in reducing pulmonary vascular resistance in patients with Eisenmenger syndrome. Specific guidelines focusing on modern therapies for Eisenmenger syndrome however do not exist to date. More recently, clinical ...
Joos Zachary P ZP Departments of Ophthalmology and Visual Sciences (ZPJ, O-OOA, BJK) and Neurology (BJK), University of Utah Health Sciences Center, Salt Lake City, - - 2014
: We present the magnetic resonance imaging findings of posterior ischemic optic neuropathy in a patient with posterior reversible encephalopathy syndrome secondary to hypertensive emergency.
Bolognesi Massimo M Massimo Bolognesi, Marco Di Pascoli, Alberto Verardo, Angelo Gatta, Department of Internal Medicine-DIMED, University of Padua, Azienda Ospedaliera Università di Padova, 35128 Padova, - - 2014
Portal hypertension is a clinical syndrome which leads to several clinical complications, such as the formation and rupture of esophageal and/or gastric varices, ascites, hepatic encephalopathy and hepato-renal syndrome. In cirrhosis, the primary cause of the increase in portal pressure is the enhanced resistance to portal outflow. However, also an ...
Siomou Ekaterini E Departments of Pediatrics, University Hospital of Ioannina, Stavros Niarchos Avenue, 45 500, Ioannina, Greece, - - 2014
Arterial hypertension (AHT) is a common finding in children with Williams-Beuren syndrome (WBS). Although cardiovascular and renal abnormalities can explain the AHT in some patients with WBS, its etiology is not fully understood and most cases are considered idiopathic. The case is reported of a 10-year-old girl with WBS who ...
Yan Zhongrui Z 1 Department of Neurology, Jining First People's Hospital , Shandong, China - - 2014
Abstract Background: The relationship between the metabolic syndrome and subclinical atherosclerosis among elderly people remains controversial. We seek to investigate the associations of metabolic syndrome and its components with subclinical carotid atherosclerosis in older people living in rural China. Methods: This cross-sectional study included 911 participants (age ≥60 years, 59.4% ...
Oosterlinck Wouter W Department of Cardiovascular Sciences, Research Unit of experimental cardiac surgery, Katholieke Universiteit Leuven, Leuven, - - 2014
The deadly quartet of the metabolic syndrome includes obesity, impaired glucose tolerance, an atherogenic lipid profile and hypertension. The synergistic effects of these comorbidities lead to a combination of functional and structural cardiomyocyte changes and finally result in a global adverse remodeling process. Overall cardiovascular outcome is significantly impaired. Furthermore, ...
Samson Susan L SL Department of Medicine, Baylor College of Medicine, One Baylor Plaza, ABBR R615, Houston, TX 77030, - - 2014
Metabolic syndrome is not a disease per se, but is a term that highlights traits that may have an increased risk of disease, approximately 2-fold for cardiovascular disease and 5-fold or more for type 2 diabetes mellitus. Obesity and insulin resistance are believed to be at the core of most ...
Marra A A Department of Neuroscienze e Scienze riproduttive ed Odontostomatologiche-Anesthesiology and Intensive Care Medicine, University of Naples "Federico II", Italy. Electronic address: - - 2014
Posterior reversible encephalopathy syndrome (PRES) is characterised by headache, visual disorders, seizures, altered mentation, consciousness disturbances and focal neurological signs. Initially described in patients with pre and eclampsia, severe hypertension, posterior reversible encephalopathy syndrome can occur in other clinical conditions such as infection, sepsis, shock, cancer chemotherapy, autoimmune diseases and ...
Zwagerman Nathan T NT Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, - - 2014
The development of Moyamoya syndrome (MMS) after cranial irradiation for pediatric tumors has been well established. However, information on the development of MMS after proton beam radiotherapy is sparse. We present the case of a 2-year-old child who developed radiation-induced MMS after treatment with proton beam therapy. Pediatr Blood Cancer ...
De Vecchis R R Cardiology Unit, Presidio Sanitario Intermedio "Elena d'Aosta" Naples, Italy - - - 2014
The authors summarize some current views regarding the pharmacologic therapies of hepatorenal and cardiorenal syndromes, respectively. A common pathogenetic background of the two edematous disorders is outlined, consisting in reduced effective blood arterial volume ‑ due to the splanchnic vasodilation in the hepatorenal syndrome (HRS) and to the fall in ...
Calcaterra Valeria V 1 Department of Internal Medicine University of Pavia and Department of the Mother and Child Health , Pediatric Unit, IRCCS Policlinico San Matteo Foundation, Pavia, Italy - - 2014
Abstract Background: An increased relative risk of diabetes, ischemic heart disease, atherosclerosis, and hypertension have been reported in Turner syndrome (TS) patients. No data are currently available on the prevalence of metabolic syndrome in TS subjects. We evaluated the frequency of metabolic syndrome in obese and nonobese patients with TS. ...
Marrone Luiz Carlos Porcello LC Service of Neurology, Instituto do Cérebro, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul , Porto Alegre, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiologic entity not yet understood, that presents with transient neurologic symptoms and particular radiological findings. Few papers show the differences between pregnant and non-pregnant patients. We review the cases of 38 women diagnosed with PRES, in order to find significant differences between pregnant ...
Kinoshita Shunsuke S Department of General Internal Medicine, Saitama Medical University , Saitama , Japan - - 2014
Abstract Aim: Recently, obesity patients have been diagnosed as metabolic syndrome. The aim of this study was to evaluate which angiotensin type 1 receptor blockers (ARBs), telmisartan or candesartan, is superior for the control of home blood pressure (BP) in the morning when the outpatient clinic BP was well controlled ...
Minakami Hisanori H Department of Obstetrics, Hokkaido University Graduate School of Medicine, Sapporo, - - 2014
As proposed criteria (Swansea criteria) for the diagnosis of acute fatty liver of pregnancy (AFLP) do not include antithrombin (AT) activity, diagnosis of AFLP may be delayed. The aim of this review is to underscore problems in the differential diagnosis of AFLP and the syndrome of hemolysis, elevated liver enzymes ...
Eto Koki - - 2014
Surgicel, an absorbable haemostat, is widely used in cardiovascular surgery. An 81-year-old woman, who was diagnosed with ischaemic mitral regurgitation, underwent mitral valve plasty and coronary artery bypass grafting. On postoperative day two, her superior vena cava (SVC) pressure gradually rose to 38 mmHg and she developed low output syndrome. ...
Hamm Christian W CW Kerckhoff Heart and Thoraxcenter, Bad Nauheim, - - 2014
Patients presenting with acute coronary syndromes (ACS) remain a challenging medical condition with potential in improving outcome despite major advances over recent years. During the year 2013, progress has been made with respect to a better understanding of the underlying mechanisms and diagnosing ACS. In addition, new studies provided fundamental ...
Liebeskind David S DS UCLA Stroke Center, Los Angeles, CA, USA. Electronic address: - - 2014
Nephrotic syndrome refers to excessive proteinuria, with associated hypoalbuminemia, edema, and hyperlipidemia. A diverse spectrum of disorders has been associated with nephrotic syndrome and related neurologic complications, although the relative infrequency of these cases limits conclusive associations. Neurologic manifestations of nephrotic syndrome may result from hypoproteinemia, hypercoagulability, hyperlipidemia, hypertension, amyloid ...
Lamy C C Department of Neurology, Université Paris Descartes, Hôpital Sainte-Anne, Paris, France. Electronic address: - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a recently proposed cliniconeuroradiologic entity with several well-known causes, such as hypertensive encephalopathy, eclampsia, and the use of cytotoxic and immunosuppressive drugs, as well as some causes more recently described. PRES is characterized by neuroimaging findings of reversible vasogenic subcortical edema without infarction. The ...
Goyal Nishant N Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), New Delhi, - - 2014
GAPO syndrome stands for growth retardation (G), alopecia (A), pseudoanodontia (P) and optic atrophy (O). To date, only about 35 cases of this extremely rare syndrome have been reported. Craniosynostosis/craniostenosis is a condition with an abnormal head shape due to premature fusion of the calvarial sutures and can be either ...
Shah Reena R Yeovil District Hospital, Yeovil, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological syndrome characterized by various symptoms of neurological disease. It has commonly been reported in association with acute hypertension, pre-eclampsia, eclampsia, sepsis, and exposure to immunosuppressants. Here, we report on a normotensive woman who developed a severe frontal headache, visual disturbances, and hypertension ...
Al Rukban Hadeel H Department of Pediatrics, King Abdul-Aziz Medical City, Riyadh, Saudi Arabia ; King Abdullah International Medical Research Centre, Riyadh, Saudi - - 2014
Infantile scimitar syndrome is a rare condition, with most of the literature reports being limited to case reports and a few case series. The aim of this study was to review patients with infantile scimitar syndrome who presented to our hospital from July 2000 to January 2011. In this retrospective ...
Kulkarni Ranganath R RR Department of Psychiatry, Sri Dharmasthala Manjunatheshwara (SDM) College of Medical Sciences and Hospital, Dharwad, Karnataka, - - 2014
Depressive symptoms are common in neurological diseases, at times posing dilemma in organic or functional origin. Cerebrovascular disease may predispose, precipitate, or perpetuate some geriatric depressive syndromes that resemble primary depressions both clinically and therapeutically in about half of the patients following acute stroke. Terson's syndrome is the direct occurrence ...
Banakar Basavaraj F BF Department of Neurology, Dr. S N Medical College, Jodhpur, Rajasthan, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a clinicoradiologic entity commonly associated with eclampsia, septicemia, chemotherapeutic drugs etc. Concurrent occurrence of Guillain-Barre syndrome (GBS) with PRES is a rare entity. Dysautonomia is a proposed mechanism for such occurrence. Here we present a non-diabetic, non-hypertensive 63-year-old male patient, who came with acute ...
Katsi Vasiliki V Department of Cardiology, Hippokration Hospital, Athens, - - 2014
Restless Legs Syndrome (RLS), is a sensory-motor neurological disorder that appears to be surprisingly common in the community. Periodic limb movements in sleep are typically encountered in more than 80% of RLS patients and comprise involuntary muscular jerks in the lower limbs, such as flexion of the knees or ankles. ...
Costa Ricardo R Department of Oncology, Real Hospital Portugues, 52010 Recife, PE, - - 2014
Reversible posterior leukoencephalopathy syndrome (RPLS) is clinical radiologic condition associated with neurological symptoms and cerebral white matter edema. It has been associated with uncontrolled hypertension, eclampsia, immunosuppressants, and more recently the use of antiangiogenic drugs. Sunitinib is an inhibitor of the vascular endothelial growth factor receptor widely used in the ...
Wang Jie J Department of Cardiology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, - - 2014
Background. To simplify traditional Chinese medicine syndrome differentiation and allow researchers to master syndrome differentiation for hypertension, this paper retrospectively studied the literature and analyzed syndrome elements corresponding to hypertension syndromes. Methods. Six databases including PubMed, EMBASE, Chinese Bio-Medical Literature Database, Chinese National Knowledge Infrastructure, Chinese Scientific Journal Database, and ...
Duga Balazs B Department of Medical Genetics, Clinical Centre, University of Pecs, Szigeti 12, Pecs H-7624, Hungary ; Szentágothai Research Centre, University of Pecs, Ifjusag 20, Pecs H-7624, - - 2014
The 4q deletion syndrome shows a broad spectrum of clinical manifestations consisting of key features comprising growth failure, developmental delay, craniofacial dysmorphism, digital anomalies, and cardiac and skeletal defects. We have identified a de novo interstitial distal deletion in a 9 month-old girl with growth failure, developmental delay, ventricular septum defect ...
Appachu M Sandhya MS Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, - - 2014
Posterior reversible encephalopathy syndrome (PRES) is a neurotoxic state coupled with a unique radio imaging appearance. We describe this rare, mostly reversible condition in five cases undergoing similar treatment under preset protocol (MCP-841) for acute lymphoblastic leukemia (ALL) at our centre. Hypertension is a well-known adverse effect of high-dose corticosteroid ...
Hunt Leanne - - 2014
Patients in the intensive care unit (ICU) are at risk of developing of intra abdominal hypertension (IAH) and abdominal compartment syndrome (ACS). This review seeks to define IAH and ACS, identify the aetiology and presentation of IAH and ACS, identify IAP measurement techniques, identify current management and discuss the implications ...
Ma Hong Yun HY From the *Division of Nuclear Medicine, Department of Radiology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY; †Department of Radiology, University of Connecticut Health Center, Farmington, CT; and ‡Department of Radiology, Maimonides Medical Center, Brooklyn, - - 2013
There are many causes of cerebrospinal (CSF) leaks. Most cases are secondary to blunt trauma and iatrogenic trauma caused by postoperative sequelae. Occasionally, CSF leakage may occur from nontraumatic or "spontaneous" causes, such as benign intracranial hypertension and "empty sella syndrome." Mass effect due to an encephalocele or meningocele may ...
Rastogi P - - 2013
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are conditions that commonly manifest in critically ill patients. These conditions are associated with a multiplicity of pathophysiological perturbations. The authors of this study retrospectively reviewed literature relating to IAH and ACS published in the last two decades to consolidate an understanding ...
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