We describe a case of preeclampsia with the HELLP (Haemolysis, Elevated Liver enzymes, Low Platelets) syndrome and highlight the delayed diagnosis due to its nonspecific presentation. This syndrome is associated with significant maternal and perinatal mortality and morbidity and we discuss the importance of early recognition of the condition, aggressive ...

Chest wall deformities may produce signs that closely mimic organic heart disease. In this category, the straight back syndrome is well recognized. Although clinical identification of this syndrome is thought sufficient to withdraw from any further investigation, its association with idiopathic mitral valve prolapse--a cardiac lesion with considerable morbidity and ...

The involvement of the 5-HT1A receptor in the 5-HT syndrome (head weaving and hindlimb abduction) induced in DBA mice by tryptamine was investigated. Methysergide, (-)propranolol and spiperone suppressed both the head weaving and hindlimb abduction induced by tryptamine. However, ketanserin and ICS 205-930 did not affect them. Haloperidol induced small ...

Chickens on 14 broiler breeder farms were examined at various times throughout their laying cycle. Antibodies to the turkey rhinotracheitis virus were common although they were not always accompanied by clinical signs of the swollen head syndrome. Ninety-nine broiler flocks were tested of which only 20 were serologically positive to ...

The first case of the H.E.L.L.P. syndrome with ophthalmic signs is described. This syndrome of pregnancy is characterized by Haemolysis, Elevated Liver enzymes and Low Platelets in association with upper abdominal pain. Diagnosis and treatment is often delayed, while a non-obstetric cause for these findings is sought. The present report ...

We report herein about lectin histochemistry of seminiferous epithelia in two infertile men with exlusely acrosomeless round-headed spermatozoa. FITC-conjugated lectins (ConA, PNA, RCA II, WGA) have been employed on tissue sections of Bouin fixed testicular biopsies. RCA II gave a dot-like fluorescence of the acrosomal region and WGA gave a ...

Secretary Back Syndrome, the title appropriate and descriptive, the concept original and useful, describes an intermittent, recurrent, symmetrical low-back pain induced by swivel-chair exposure. The swivel chair, by its very mechanical nature, frequently invites poor posture, causing a symmetrical, recurrent, lumbo-sacral strain. Swivel-chair exposure, transiency and recurrence of low-back pain, ...

In 1982 Weinstein reported a syndrome marked by Hemolysis, Elevated Liver enzymes, Low Platelets (HELLP Syndrome). Following that report a critical review by MacKenna & Coll. reported that typical signs of the syndrome (observed in 223 cases of preeclampsia) were related to the preeclampsia so denying any nosografic autonomy to ...

The fibroblast strain GM3498 and the lymphoblastoid line GM4408 have been established from the same Bloom's syndrome patient, as confirmed by DNA hybridization with hypervariable probes and isoenzyme analysis. Strain GM3498, but not GM4408, exhibits a high frequency of spontaneous sister chromatid exchange, hypersensitivity to ethyl methanesulphonate and an anomalously ...

Disc deterioration and pain provocation in different low-back pain syndromes was studied using computed tomography (CT) discography. Data were prospectively collected for 300 patients (816 discs). Patients were classified by their pre-discography diagnosis of disc herniation (DH), degenerated disc (DD), lumbar syndrome (LS), lumbar radicular syndrome (LRS), or other. The ...

Although Reiter's syndrome uncommonly affects the cervical spine, involvement of the craniocervical articulations does occur and may be manifested as nonreducible rotational head tilt. Computerized axial tomography with reformatted images was helpful in assessing the anatomy of this area in our patient with significant head tilt and abnormal head position.

Dapsone (4-4-diaminodiphenyl-sulfone) is a member of the sulfone group of antibiotics used in the treatment of leprosy and various dermatitidies and more recently employed in the management of local reactions to the bite of the brown recluse spider, Loxosceles reclusa. A dapsone hypersensitivity syndrome, consisting of fever, headache, nausea, vomiting, ...

The effects of standing, and lying with the back extended, on F wave minimal latency and F chronodispersion were studied in patients with lumbar canal stenosis, lumbosacral root compression syndromes, and low back pain. Standing for 3 min produced increased F chronodispersion in lumbar canal stenosis and root compression syndromes ...

Of all the conditions that confront the chiropractor, the degenerative low back syndrome is one of the most frequently encountered, but least understood, problems. This paper will briefly give the rationale in using a rigid, decompressive, custom molded fiberglass orthosis to effectively manage the progressive clinically symptomatic destabilized motor unit. ...

A severe consequence of pregnancy-induced hypertension can be the development of HELLP syndrome (H = hemolysis; EL = elevated liver enzymes; LP = low platelets). The etiology and clinical manifestations of HELLP syndrome are discussed through a review of research findings and a case study. Nursing interventions to facilitate recognition ...

Psychiatric manifestations of 72 CATEGO Class S+ schizophrenics were studied using a syndrome check list. Comparison of syndromic manifestations with other published works revealed significant cross-cultural differences. It was observed that Indian CATEGO S+ patients had significantly less depression, tension and anxiety. Differences in nuclear syndrome and Schneider's First Rank ...

The angry back syndrome (ABS) was investigated using Trafuril cream and prostaglandin synthetase inhibitors. Trafuril produced an increase in the numbers and intensity of patch test reactions which was partly abrogated by aspirin and indomethacin. Irritant reactions were not affected. We suggest that Trafuril may increase the sensitivity of the ...

This report is based on a 3 month study visit to the United States undertaken in the summer of 1985 and sponsored by the Kodak Travel Scholarship. The current attitudes and trends in the investigation of patients with sciatica and low back pain syndromes will be discussed, with a particular ...

Two mechanisms by which patients compensate for congenital nystagmus are assumption of a head position that places the eyes in a "null zone" of least nystagmus, known as nystagmus compensation syndrome (NCS), and convergence to dampen nystagmus, known as nystagmus blockage syndrome (NBS). We followed five patients in two groups ...

Seemingly mild head injuries frequently result in persisting postconcussive syndromes. The etiology of these symptoms is often controversial. Neuropsychological, neurophysiological, and neuropathological evidence that brain damage can occur in the absence of gross neurological deficits after mild injuries is reviewed. Direct impact to the head is not required to cause ...

The bobble-head doll syndrome has been associated with third ventriculomegaly due to cysts or aqueductal stenosis. A case is described in which the aqueduct and fourth ventricle are enlarged, but the third ventricle is not. The unifying pathogenesis for this and previous cases is pressure on the dorsomedial red nucleus.

Low back syndromes in dancers are intimately related to flaws in the dance technique, especially postural faults and incorrect movements into hyperextension of the hip. The pathology produced by the technical faults is multiplied in those dancers whose physiques are not ideally suited to withstand the stresses of classical training. ...

The "HELLP syndrome" refers to the occurrence of thrombocytopenia, elevated liver enzymes and, at times, hemolysis in patients with preeclampsia. Although uncontrolled series have reported a reversal of thrombocytopenia and elevated liver enzymes with aspirin and colloid infusion, most authors recommend that delivery be done soon after the diagnosis is ...

A 1-year-8-month-old boy with mucocutaneous lymph node syndrome (Kawasaki disease) complained of left hip pain. Radiographic examination revealed avascular necrosis of the femoral head. We suspect that arteritis, aneurysm, or subsequent thrombosis, which are histopathologically the main lesions in mucocutaneous lymph node syndrome, may induce ischemic changes in the femoral ...

The allopurinol hypersensitivity syndrome is a rare adverse drug reaction. It usually occurs in patients with impaired renal function or when allopurinol is prescribed with a thiazide diuretic. The recognition of the characteristic features of the syndrome is vital since early aggressive therapy is indicated. A case of allopurinol hypersensitivity, ...

Down syndrome is caused by trisomy of chromosome 21 and is comprised of a constellation of abnormalities including neuropathological features that closely resemble those characterizing the neurodegeneration of Alzheimer disease. Because cultured cell lines from patients with Alzheimer disease and other neurodegenerations have a hypersensitivity to the lethal effects of ...

Break dancing is a popular contemporary activity that has important medical implications. Some dancers have complained of lower back pain and difficulty in bending over-the "breakdance back syndrome." Break dancing injuries are often comparable to the orthopedic injuries that occur in unsupervised athletic activities. Careful screening, instruction, supervision and training ...

Lymphocytes and fibroblasts from people with Bloom syndrome, an autosomal recessive disorder associated with a predisposition to a wide variety of cancers, are known to be hypersensitive to ethylating agents as measured by sister chromatid exchange induction. Recently, hypersensitivity to cell killing by mitomycin C has also been reported in ...

Two weeks after initiation of therapy with 1.2 gm/day quinidine sulphate, a 67 year old patient developed clinical and laboratory features of sicca syndrome. These subsided upon discontinuation of the treatment, but reappeared on a second challenge with this drug. Sicca syndrome represents a previously undescribed hypersensitivity reaction to quinidine.

Many children with Brown's superior oblique tendon sheath syndrome do not have full fusion and stereopsis. Of 28 such patients 8 failed to demonstrate orthophoria in their assumed head position, and many continued to have a head tilt with one or the other eye patched. All eight showed an appropriate ...

The sacroiliac joint can give rise to a syndrome of buttock and leg pain which is often difficult to differentiate from other causes of low--back pain. In some cases the syndrome may go unrecognized and may be a contributing factor in failed low-back surgery. The syndrome often occurs in the ...

Synthesis and distribution pattern of intracellular GAG were evaluated skin fibroblasts cultured from two patients with Lowe's syndrome and control children. After trypsinization and Pronase treatment of fibroblasts at around the tenth generation of passage and at the stage of culture confluence, GAG were isolated by precipitation with CPC in ...

We describe a patient with cough syncope who was found to have carotid sinus hypersensitivity with mixed cardioinhibitory and vasodepressor responses. Symptoms were ameliorated by denervation of the more hypersensitive carotid sinus. Spontaneous atypical Wenckebach cycles in this patient were caused by the combined hypersensitive cardioinhibitory and vasodepressor responses. This ...

The straight back syndrome, consisting of loss of normal upper thoracic spinal curvature associated with cardiac murmurs and radiographic cardiomegaly is considered a form of 'pseudoheart disease' which has been attributed to squashing of the heart in the reduced AP diameter of the chest. During an 18-month period 31 patients ...

Most cases of low back pain fall into the category of nonspecific low back pain in which no specific pathology can be detected by x-ray, laboratory tests, or biopsy. In the authors' experience about 50% of the patients falling into this group have a clinical picture characterized by symptoms and ...

A new syndrome called hereditary vibratory angioedema (HVA), characterized by pyruritis and angioedema at the site of a vibratory stimulus, was recently reported as a model of nonimmunologic immediate hypersensitivity. The biochemical mediator of this syndrome was not defined initially. This study now demonstrates that in vivo histamine release occurs ...

The head injury syndrome is a series of psychological characteristics observed in survivors of traumatic head injuries referred to a hospital-based rehabilitation centre. Severe cases of head injury syndrome are readily identifiable as cases of organic dementia. In less florid cases patients easily pass for normal in routine consultation situations, ...

Although hypersensitivity has been postulated, the etiology of Sweet's syndrome has never been elucidated. In the present case intradermal tesing with viridans streptococcus led to an immediate reaction and reproduced a lesion clinically and histologically identical to that of the primary disease. Other bacterial and fungal antigens failed to elicit ...

The syndrome of low intracranial pressure may develop in a variety of circumstances, e.g. after lumbar puncture, following head injury and intracranial operations. It sometimes occurs after viral meningitis. The case history is described of a woman in whom the disorder was unusually severe and persistent. Interesting radiological features were ...

Ten patients with proved hypersensitivity of one or both carotid sinuses and with symptoms of recurrent lightheaded spells and syncope had implanted a permanent transvenous demand pacemaker. In a follow-up course ranging from 6 to 55 months there has been no recurrence of lightheadedness or syncope in any of the ...

Five cases of Stevens-Johnson syndrome are described in patients with penetrating head wounds who were treated with Penicillin, streptomycin, sulphadiazine and the anticonvulsant drugs, epanutin and phenobarbitone. One patient who continued to have only his anticonvulsants after the appearance of his skin eruption, died. In two other cases, epanutin and ...

Available methods for titrating diphtheria and tetanus antitoxin at low concentrations in human or animal blood are surveyed, with special attention to the amount of serum required for the test.In vivo methods, especially the rabbit or guinea-pig intradermal test for diphtheria and the mouse test for tetanus, are precise and ...

A 17-year-old woman developed high fever, lymphadenopathy and elevated liver enzymes 4 days after the initiation of diphenylhydantoin (DPH) for seizure prophylaxis. There was no skin rash. The extensive tests for infectious sources were negative. After the discontinuation of DPH, the fever and lymphadenopathy rapidly resolved, and the elevated liver ...

The modalities at present in use for the treatment of soft-tissue injuries responsible for the low back strain syndrome are predominantly passive, yet similar soft-tissue injuries elsewhere in the body receive and respond to an early program of active movement. To assess the feasibility of such an approach to the ...