Mary is a 55 year old woman on hormone replacement therapy. She is flying to the UK with her husband in a few weeks time, and is concerned about the recent media attention given to the 'economy class syndrome'. Mary's sister developed a similar problem after surgery some years ago. ...

An interface bioreactor was used for the enantioselective degradation of (RS)-ibuprofen (IBU). An isolated yeast, Trichosporon cutaneum KPY 30802, preferentially degraded (R)-IBU to accumulate (S)-isomer. The addition of hydroquinone (10 mM) into a hydrophilic carrier was effective for the elevation of enantiomeric excess and the repression of excess degradation of ...

Gradenigo syndrome consists of the association of otitis media, facial pain in regions innervated by the first and second division of trigeminal nerve and abducens nerve paralysis. It is caused by osteitis of the petrous apex (PA) and is a very rare complication of otitis media. Its treatment usually consists ...

The articles highlighted in this issue are three reports by Kevin Crofton and colleagues dealing with neuromodulatory effects of PCB (Gilbert, Mundy, and Crofton, pp. 102-111; Roegge et al., pp. 121-130; and Crofton et al., pp. 131-140).

Gradenigo's syndrome, which is characterised by the triad of suppurative otitis media, pain in the distribution of the trigeminal nerve, and abducens nerve palsy may give rise to potentially fatal complications. Knowledge of the aetiology and appropriate investigations can lead to early diagnosis. A case is reported which illustrates this.

The present work describes the insecticidal potentiality from Microcystis aeruginosa (cyanobacteria) and Parasicyonis actinostoloides (Sea anemone) water extracts against 3rd larval instar of medical insects (Musca domestica and Culex pipiens) and 4th larval instar of agriculture insects (Spodoptera littoralis and Agrotis ipsilon. The LD50s of M. aeruginosa extract were 1.94, ...

Deficiencies of 7 enzymes in the heme biosynthetic pathway result in the development of porphyrias. Two of the porphyrias, aminolevulinate dehydratase deficiency porphyria and acute intermittent porphyria do not have cutaneous findings. Cutaneous findings in the other porphyrias could be subdivided into acute phototoxicity and subacute phototoxicity. In addition, 2 ...

Acute intermittent porphyria (AIP) is an autosomal-dominant disease caused by a deficiency of porphobilinogen (PBG) deaminase. Patients with AIP present with neurological syndromes such as autonomic neuropathy, peripheral axonal neuropathy or central nervous system dysfunction. We report serial MRI of a patient with AIP who had cortical and subcortical cerebral ...

The cyclic irradiation sidebands appearing in homonuclear adiabatic decoupling are calculated in detail, which reveals the origin of the antisymmetric sidebands. The sidebands can be inverted by inserting an initial decoupling with a different period, but the same f1rms as the main decoupling that is required for Bloch-Siegert shift compensation. ...

PURPOSE: To describe the clinical and magnetic resonance imaging findings of a patient with Gradenigo syndrome. METHODS: A 4 1/2-year-old boy developed Gradenigo syndrome with unilateral facial pain, ophthalmoplegia, and facial weakness secondary to ipsilateral otitis media. The clinical, laboratory, and radiologic findings are discussed. RESULTS: The patient was treated ...

BACKGROUND: Myelography is routinely performed safely using nonionic water-soluble radiographic contrast media. However, inadvertent introduction of ionic contrast media into the thecal space can result in a syndrome of spasms and convulsions, which can lead to death if not recognized and dealt with in a timely manner. METHODS: We report ...

Williams syndrome is a true multiple congenital anomalies mental retardation syndrome affecting the vascular, connective tissue and the central nervous system. Affected individuals have a distinctive neuropsychological profile characterized by extremely poor visuospatial skills but relatively preserved verbal skills. A very striking characteristic is the hyperacusis or over-sensitivity to particular ...

Chronic sinusitis is frequently associated with chronic lower respiratory tract diseases, and the association is referred to as sinobronchial syndrome (SBS). This study was carried out to determine the incidence of otitis media with effusion in the patients with sinobronchial syndrome and to investigate the efficacy of low-dose and long-term ...

The endogenous neuropeptide Tyr-MIF-1 (Tyr-Pro-Leu-Gly-amide) has been shown to counteract various opiate actions. In the current study, third ventricular injection of 35 micrograms Tyr-MIF-1 protected by the enzyme inhibitor bestatin precipitated an abstinence syndrome in morphine-dependent rats, but not in opiate-naive rats. The results raise the possibility that Tyr-MIF-1 might ...

Unsolicited oral spelling has been observed in conduction aphasics during word-production difficulty (Kohn, 1985), but has never been examined systematically. In the present study, the possible role of oral spelling in the word-production process of a conduction aphasic (JM) is explored. Oral spelling occurred much more frequently during picture naming ...

The effect of a pectin-supplemented diet in short gut syndrome was investigated in a 3-year-old boy. Nitrogen absorption was higher and stomach-to-anus transit time was prolonged during pectin supplementation of the enteral feed. Pectin supplementation had no adverse effects on electrolyte balance or glucose absorption. These data indicate that pectin ...

Williams syndrome is characterized by cardiac defects, varying degrees of physical and developmental delay, stellate eye pattern, possible elevated serum calcium level, and elfin/pixie facial features. A problem perhaps unique to these children is hyperacusis that can be severe enough to disrupt many routine daily activities. Parental questionnaires were used ...

A patient with bronchial asthma and hypereosinophilia developed acute acalculous cholecystitis. Histopathologic study of the surgically removed gallbladder revealed allergic granulomatosis and angiitis (Churg-Strauss syndrome). Allergic granulomatosis and angiitis having acute acalculous cholecystitis as an initial manifestation is rare. It should be recognized that acute acalculous cholecystitis may be the ...

In the November-December 1988 issue of Physician Executive, Dr. Marks' article outlined typical reactions to the uncertainty of being involved in a merger or consolidation. The article introduced the concept of the "merger syndrome," which encompasses executives' stressful reactions to a combination and the development of a crisis management orientation. ...

Children aged six months to 10 years in one practice who were diagnosed with acute otitis media were examined one, three, six and 12 months after diagnosis by a general practitioner and an otolaryngologist on the same day using pneumatic otoscopy. Tympanometry and pure tone audimetry were also carried out. ...

The efficacy of Arosurf MSF alone and in combination with three preparations of Bacillus thuringiensis var. israelensis (B.t.i.) against Anopheles albimanus larvae, pupae and eggs was determined by bioassay. Arosurf MSF alone was effective against the egg, 4th larval instar and pupal stages. All Arosurf MSF and B.t.i. combined formulations ...

Thirty prepubertal boys with fragile X syndrome (fra[X]) were evaluated retrospectively to document the incidence of recurrent otitis media by physician records. The number of documented otitis media infections in the first five years of life was statistically more than those of the normal male siblings and of unrelated, cytogenetically ...

The endogenous compounds, serotonin (5-HT) and tryptamine (TA), have been found to alter function in the CNS, supporting the hypothesis that they serve as neurotransmitters. It is reported here that intrathecal injections of either 5-HT or tryptamine elicited similar behavioral syndromes consisting of caudally-directed biting, or licking and scratching. Serotonin ...

A 56 year old woman with acute intermittent porphyria presented mainly motor polyneuropathy, ophthalmoparesis of probable supranuclear origin and a mild organic brain syndrome. The neurological complications gradually cleared during a course of plasmapheresis. The fairly rapid improvement could conceivably have been fortuitous but it may well have been due ...

The immotile-cilia syndrome is caused by a hereditary, inborn, ultrastructural defect of the cilia, rendering them immotile or poorly motile and thereby abolishing mucociliary clearance. Five cases are presented and the otologic manifestations are described in some detail. The syndrome should be suspected in children who have a persistent secretory ...

We here present a clinical study of 37 patients with Meniere's syndrome. Meniere's syndrome can occur subsequent to and in some cases simultaneously with chronic otitis media. When otitis media which has occurred many years earlier in childhood becomes inactive, leading to sequelae of Meniere's later in life, full-blown Meniere's ...

Clinical data and follow-up evaluations of 83 cases of peripheral vestibular syndrome in the dog were reviewed. The absence of physical abnormalities of the tympanic membrane and absence of radiographic changes within the tympanic bulla or petrous temporal bone were the criteria used to make the diagnosis of idiopathic benign ...

Three new cases of hydrops of the gallbladder associated with mucocutaneous lymph node (Kawasaki) syndrome are presented. The increasing frequency of association of those two entities is emphasized. Ultrasonography is ideal for confirming the diagnosis of gallbladder hydrops and for follow-up. The preferred treatment is medical, and surgical intervention is ...

ACTH1-24 and beta-endorphin simultaneously injected at 5-10 microgram dose into the lateral ventricle, reciprocally suppress most of their respective behavioural effects (stretching-yawning syndrome, sexual excitement and hyperalgesia for ACTH1-24 and catalepsy and analgesia for beta-endorphin). The results obtained support the hypothesis that ACTH1-24 and beta-endorphin might interact antagonistically at CNS ...

Effects of cooperative, competitive, and individualistic goal structures compared on the dimensions of interpersonal interaction and attraction. Subjects were nonhandicapped and Down syndrome junior high school students who participated in eight weekly sessions of recreational bowling. Results indicated that significantly more positive interactions and evidence of greater interpersonal attraction took ...

In the last three decades, more attention has been put upon neurogenic intermittent claudication, also called pseudoclaudication. The syndrome usually develops in patients with congenital narrow spinal canal and secondary additional narrowing. Two cases of spondylolisthesis with neurogenic intermittent claudication are presented. The pathogenesis, symptoms and findings of neurogenic intermittent ...

Experiments on fertile hens' eggs have shown that an excess of vitamin A has a highly specific effect on the migration of cranial neural crest cells in the early stages of chick embryogenesis. Migration is disrupted and retarded. This is consistent with the causal mechanism proposed by Poswillo for the ...

The pseudoclaudication syndrome, now a well known neurological entity, can simulate intermittent claudication of arterial origin in its clinical appearance. Walking and sometimes simply standing upright for a while can cause transitory pain, numbness or weakness in the legs. The symptoms are caused by entrapment of the cauda equina fibers. ...

The effect of four viper venoms (Oxyuranus scutellatus, Notechis scutatus scutatus, Echis carinatus, Naja nigricollis) on prothrombin Padua has been studied. Using Oxyuranus scutellatus venom and Notechis scutatus scutatus venom, prothrombin activity resulted to be moderately decreased similarly to what observed with other one-stage and two-stage methods. On the contrary, ...

Acute emphysematous cholecystitis is an uncommon condition caused by gas-forming organisms and characterized by the presence of gas in the wall and lumen of the gallbladder. Its incidence is higher among male diabetics. AEC in an elderly North American diabetic man with Indian ancestry is reported with a brief review ...

A series of 65 cases of acute cholecystitis from among 500 patients on whom cholecystectomy was performed by the author is presented. Early cholecystectomy was the operation of choice in 63 and cholecystostomy in two. The operative mortality for cholecystectomy was 1.6%; the postoperative morbidity was low and there were ...

Two types of bilateral amygdalar lesions were performed successively. The first operation, involving the dorsomedial part, produced aphagia and subsequent hypophagia, vomiting and apathy. Consequently the body weight was reduced. After a few weeks partial recovery occurred. The second operation, involving the lateral part of the amygdaloid complex, produced hyperphagia, ...

1. The hyperactivity and hyperpyrexia produced by L-tryptophan in rats treated with a monoamine oxidase inhibitor was inhibited by chlorpromazine.2. Chlorpromazine did not inhibit the increased rate of synthesis of brain 5-hydroxytryptamine (5-HT) produced by tryptophan loading.3. Hyperactivity and hyperpyrexia were also produced by 5-methoxy-N,N-dimethyltryptamine (5-MeODMT) in rats. Pretreatment with ...