We describe a 23-yr-old man with congenital unconjugated hyperbilirubinemia secondary to uridine diphosphate glucuronosyltransferase deficiency, and who cannot readily be classified as type I or type II Crigler-Najjar syndrome. After an episode of kernicterus in childhood he was treated with phenobarbital with a resultant marked decrease in his serum bilirubin ...

The acute vanishing bile duct syndrome can be defined as an irreversible, rejection-related condition that affects hepatic allografts within 100 days after orthotopic liver transplantation and whose presence requires retransplantation. We have observed the acute vanishing bile duct syndrome in 5 of 48 consecutive patients (approximately 10%) who underwent orthotopic ...

A 75-year-old woman developed acute urinary retention after ingestion of 20 100 mg ethchlorvynol tablets in a suicide attempt. To the authors' knowledge acute bladder dysfunction has not been previously ascribed to ethchlorvynol, but has been described often with therapy with various psychotropic medications. The mechanism of such bladder dysfunction ...

Two patients who required ventilatory support for acute pulmonary disease failed to be weaned when they developed the Guillain-Barré syndrome. Respiratory muscle weakness was a major sign of their acute neuromuscular disease because the manifestations of critical illness obscured the progressive paralysis. Both cases illustrate the difficulty in diagnosing acute ...

We have described a 34-year-old woman with an acute illness that meets the clinical criteria for the diagnosis of Kawasaki disease (mucocutaneous lymph node syndrome). Striking histopathologic changes found in an anterior cervical lymph node were multifocal acute necrosis and fibrin thrombi occluding small blood vessels. Biopsy of a cervical ...

Acute renal failure due to tubulo-interstitial nephritis developed in a 15-year-old girl. The disease was accompanied by uveitis and an inflammatory syndrome, consisting of a markedly increased erythrocyte sedimentation rate and high serum gamma globulin levels. The nephropathy as well as the inflammatory syndrome subsided spontaneously. A topical antiphlogistic treatment ...

The acute tumor lysis syndrome occurs rarely in nonhematologic malignancies. This patient, a 34-year-old woman with metastatic medulloblastoma, was receiving palliative radiotherapy for a rapidly expanding abdominopelvic mass. After a total of 300 rad, the patient developed the biochemical hallmarks of the acute tumor lysis syndrome, hyperuricemia, hyperkalemia, hyperphosphatemia, and ...

The syndrome of opsoclonus and polymyoclonus developed in an infant who had acute meningoencephalitis with ataxia. A low-density cerebellar lesion was noted by computed tomography, subsequently resolving with residual cerebellar atrophy. The infant recovered completely, except for a mild intention tremor. This was the first documentation, to our knowledge, of ...

Report of a 19-year-old man who was admitted to the hospital after vigorous exercise with signs of the "acute abdomen" syndrome. Since intestinal reasons for the complaints were excluded, a myocardial infarction was considered. However, the excessively increased serum CK levels indicated a disorder of the voluntary muscles. A biopsy ...

In a case of acute Reiter's syndrome with severe vulvitis the diagnosis was based on the presence of a vaginal discharge and dysuria, arthritis, conjunctivitis, buccal ulceration, keratodermia blenorrhagica, and HLA B27 tissue-typing antigen. The vulval lesions were similar in appearance to those of circinate vulvitis. The acute histological change ...

Agitation in elderly patients is often caused by acute cerebral failure, more commonly called acute brain syndrome, delirium, or acute confusional state. Defects in cognition, sleep-waking cycles, and psychomotor behavior result. Careful history taking, physical examination, and laboratory testing may reveal a specific, reversible organic factor related to the acute ...

Branhamella (Neisseria) catarrhalis was recovered from urethral exudates of three men with acute urethritis. In all cases gram stain of the urethral exudates revealed intracellular gram-negative diplococci morphologically compatible with Neisseria gonorrhoeae. Branhamella (Neisseria) catarrhalis should be considered as a potential cause of acute urethritis in men with urethral discharge ...

An unusual association of small bowel volvulus and sigmoid volvulus occurring concurrently and causing gangrene in both organs is presented. The clinical and pathological correlations and surgical management of this rare entity are discussed.

The data from the charts of 109 infants who were younger than 9 months of age and who had been hospitalized with acute diarrheal syndrome in 1978 were compared with data from the charts of 108 healthy infants of the same age range with the same sex and ethnic distributions ...

An 18-year-old woman developed acute polyarthritis one week and bilateral, acute, mucopurulent conjunctivitis and sterile pyuria two weeks after onset of Campylobacter jejuni enteritis. The conjunctivitis resolved spontaneously in one week and the arthritis in two months. The patient had HLA-B27 antigen. Campylobacter organisms may lead to Reiter's syndrome in ...

We report our experience in the acute management of a seven-year-old child with severe hemolytic uremic syndrome. On three separate occasions, acute neurologic signs dramatically resolved during simultaneous exchange transfusion and hemodialysis. The ease with which exchange transfusion may be combined with acute hemodialysis is discussed. In selected cases of ...

The hypothesis that the elements essential for the induction of acute cholecystitis are the presence of lithogenic bile and cystic duct occlusion was tested in the prairie dog gallstone model. Neither the presence of gallstones alone nor acute cystic duct occlusion alone resulted in acute inflammation of the gallbladder. Acute ...

Comparison of the blood and hearts of birds dying from Acute Death Syndrome and of normal healthy birds from seven different broiler chicken flocks revealed no consistent differences. Marked changes in serum levels of potassium, phosphorus, magnesium, sodium, and glucose were noted to occur after death in birds dying from ...

Acute calcific quadriceps tendinitis can be the cause of acute periarthritis of the knee. Physical examination can detect cellulitis and a tender tendon sheath. Lateral roentgenograms of soft tissues show thickening of the tendon and sometimes small flecks of amorphous calcification within the body of the tendon near the attachment. ...

A gastro-enteritis syndrome mimicking feline panleukopaenia was diagnosed in young dogs in the Republic of South Africa. Parvovirus was demonstrated by electron microscopy in the faeces of these animals. In addition an acutely fatal, acute to sub-acute non-purulent interstitial myocarditis occurred in pups in the same area. Histopathologically large basophilic ...

Reversible acute organic brain syndrome is described in a patient receiving disulfiram, 250 mg daily. Slowing of the electroencephalogram (3 to 4 cycles per second) in the occipital region resolved ten days after discontinuation of disulfiram. Acute organic brain syndrome induced by disulfiram is not rare but is often not ...

Three cases of acute retinal necrosis are presented. Acute retinal necrosis is an unusual syndrome which is the result of severe contusion to the globe. It is characterized by large irregular retinal holes with pieces of necrotic retina in the adjacent vitreous, retinal edema and hemorrhage surrounding the holes, underlying ...

Acute venereal arthritis, a syndrome of fever and inflammatory arthritis following recent sexual intercourse, is a frequently misdiagnosed arthritic presentation. Nearly half of 39 patients admitted with a diagnosis of acute gonococcal arthritis were subsequently recognized as having acute Reiter syndrome. A retrospective study of both diseases revealed differentiating features ...

A young woman developed the characteristic clinical and fluorescein angiographic findings of acute posterior multifocal placoid retinal pigment epitheliopathy while being treated for acute thyroiditis. Widespread involvement of the cornea, uveal tract, as well as the optic nerve and retina indicate a generalized ocular inflammation in the clinical course of ...

Twenty-eight Friesland calves were infested at 7 to 11 months of age with 5 000-45 OOO cercariae of Schistosoma mattheei. At 7 to 8 weeks post-infestation the majority developed an acute intestinal syndrome characterised by diarrhoea or dysentery, anorexia and loss of condition, from which they recovered spontansously. The severity ...

Insidious development of high-tone sensorineural hearing loss may be associated with diving, but the evidence is not certain and further research is needed. 'Internal ear barotrauma' can cause an acute or relatively acute onset of hearing loss and/or vertigo, and it may be that 'alternobaric vertigo' provides a link between ...

While rheumatic fever is relatively uncommon except where there are poor and crowded living conditions, sporadic acute attacks continue to occur in a family or pediatric medical practice. The physician's role in management of the sore throat in the diagnosis of suspected cases of rheumatic fever and in follow-up for ...

Of 53 patients with acute uncomplicated gonorrhea treated with amoxicillin 2 g and probenecid 1 g orally as a single administration, six failed to return for follow-up examination, 10 developed postgonococcal urethritis and one was a treatment failure. The remainder achieved symptomatic cure in an average of 2.3 days. Adverse ...

The hyposideremia of inflammation was found to be based on a three-step mechanism involving lactoferrin, the iron-binding protein from the specific granules of neutrophilic leukocytes. (a) Lactoferrin is Released from Neutrophils in an Iron-Free Form. When phagocytosis was induced in neutrophils by zymosan or bacteria, lactoferrin was recovered in the ...

In three patients with acute torsion of the spleen in the tropics the presenting symptoms included an abdominal mass, pain, and vomiting. In malarious areas adults usually know that they have splenomegaly and hence this fact should be ascertained in the clinical history. In an acute abdominal catastrophe, with a ...

Two patients with anorexia nervosa were treated on a general surgical unit for acute gastric dilatation. In both cases the dilatation rapidly followed an increase in the usual low dietary intake of the patients, and the ingestion of extra food may have initiated the acute episode. Conservative treatment with parenteral ...

A new enterovirus, now classified as enterovirus type 70, was isolated from the conjunctiva of patients with acute haemorrhagic conjunctivitis during the 1971 epidemics that occurred in Japan, Singapore, and Morocco. These epidemics were parts of a pandemic involving Africa (Algeria, Ghana, Morocco, Nigeria, and Tunisia), Asia (Cambodia, China (Province ...

At the end of 1972 two new "best-buy" district general hospitals should open at Bury St. Edmunds and Frimley, eventually serving their catchment areas at a ratio of two acute beds per 1,000 population. This study shows that one of these areas is already operating below this projected target as ...

A controlled study was made of penfluridol medication consisting of a single weekly oral dose of 30 mg in 30 patients with acute psychoses of varying type and origin. This medication was found to be effective. No significant side effects occurred.Several long-acting neuroleptics for injection are now available. The development ...

Eight patients with proved brucella infection were treated with trimethoprim-sulphamethoxazole. The dose varied from two to four tablets given twice daily for three weeks. Clinical response was rapid and all patients were asymptomatic and afebrile within two to seven days of starting therapy. Three patients relapsed clinically and bacteriologically within ...

Three patients developed symptoms suggestive of acute schizophrenia. In each case there were no abnormal neurological findings on admission to hospital. Within a few days clinical evidence of encephalitis became apparent, and appropriate treatment was given. Only one patient made a full recovery.

A patient is described in whom the Dubin-Johnson syndrome was diagnosed after an attack of acute hepatitis at the age of 21. In the eight years following the hepatitis Dubin-Johnson pigment, initially scanty, developed to classical proportions. The defect in intracellular transport of bilirubin was thought to precede the attack ...

Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case. The diagnosis was made by serological tests, and in three of the four cases was confirmed by positive cultures from bone marrow (one ...

Thesis (Ph.D.) - University of Queensland, 2004.

Locked-in syndrome is a devastating result of brain injury. It is rare and specialist care is crucial to help patients have a meaningful life.

Survival is uncommon in cases of acute bilateral cortical necrosis. Three cases admitted to the renal unit at Newcastle have regained useful renal function after oliguric phases of 38, 46, and 120 days.Prolonged periods of intermittent dialysis are justified in patients in whom a firm diagnosis of acute cortical necrosis ...

Between November 1962 and March 1963, myxoviruses were isolated from 95 of 224 children (40.5%), most of whom were aged less than three years, who were admitted to The Hospital for Sick Children, Toronto, with acute laryngotracheobronchitis (tracheitis or croup). Viral isolates included 87 strains of Parainfluenza-1, five of Parainfluenza-3, ...