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Kanaheswari Yoganathan Y Department of Paediatrics, Universiti Kebangsaan Malaysia, Kuala Lumpur, - - 2014
Congenital dermal sinus (CDS) and occult spinal dysraphism are suspected when a cutaneous marker overlies the spine of a newborn. CDS can have the appearance of a simple dimple and occur within the gluteal cleft without any skin markers. CDS are the commonest cause of intramedullary spinal cord abscess.
Jaswal Dharmvir S DS 1Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD. 2National Institutes of Health Library, National Institutes of Health, Bethesda, - - 2014
Since publication of the Respiratory Management of Acute Lung Injury and Acute Respiratory Distress Syndrome (ARMA) trial in 2000, use of tidal volume (VT) less than or equal to 6 mL/kg predicted body weight with corresponding plateau airway pressures (PPlat) less than or equal to 30 cm H2O has been ...
Buser G L GL Acute and Communicable Disease Prevention, Oregon Public Health Division, Oregon Health Authority , Portland, OR , - - 2014
Abstract Context and objectives. Synthetic cannabinoids are illegal drugs of abuse known to cause adverse neurologic and sympathomimetic effects. They are an emerging health risk: 11% of high school seniors reported smoking them during the previous 12 months. We describe the epidemiology of a toxicologic syndrome of acute kidney injury ...
Zheng Zhenfeng Z Department of Nephrology, General Hospital of Tianjin Medical University , Tianjin , - - 2014
Abstract Background: Tiopronin, a glycine derivative extensively used to treat cystinuria and hepatic cell injury, can give rise to rare complications such as proteinuria and nephrotic syndrome. However, the pathological characteristics of this secondary nephropathy are poorly understood. Here, we report a case of tiopronin-induced nephrotic syndrome. Case presentation: A ...
Yiş Uluç U Division of Child Neurology, Department of - - 2014
Capillary malformation-arteriovenous malformation (CM-AVM) is a recently identified autosomal dominant disorder. Arteriovenous lesions have been reported in the brain, limbs, and face. We report a 7-year-old patient with CM-AVM with spinal AVM, which is a rarely reported association.
Barlow Karen M - - 2014
By the age of sixteen, one in five children will sustain a mild traumatic brain injury also known as concussion. Our research found that one in seven school children with mild traumatic brain injury suffer post-concussion syndrome symptoms for three months or longer. Post-concussion syndrome is associated with significant disability ...
Kenz Hanane El HE From the Department of Blood Transfusion (HEK), and Department of Anaesthesiology, CHU Brugmann-HUDERF, Free University of Brussels, Brussels, Belgium - - 2014
Transfusion-related acute lung injury (TRALI) is defined as the onset or the worsening of respiratory distress within 6 h of the transfusion of a plasma-containing blood component. It is currently considered to be one of the leading causes of severe posttransfusion morbidity and acute mortality in countries with a high development ...
Naha Kushal K Department of Medicine, Kasturba Hospital, Manipal, Karnataka, - - 2014
We report the case of an 18-year-old girl presenting with shock following ingestion of 85 mg of amlodipine and 850 mg of atenolol with suicidal intent. Subsequently, the patient developed severe metabolic acidosis, acute kidney injury, and acute respiratory distress syndrome, which were managed conservatively. The patient ultimately made a ...
Desai Manish H - - 2014
Background Obstruction of the third part of the duodenum (D3) is a very rare cause of gastric outflow obstruction. Rapid weight loss is the biggest risk factor. Patients seen in acute rehabilitation settings, not uncommonly, have a period of rapid weight loss. We report two cases of superior mesenteric artery ...
Li J J Department of Cardiology, Beijing Chaoyang Hospital, Capital Medical University, 100020, Beijing, - - 2014
This study tested the associations between metabolic syndrome, postprocedural myocardial injury, and clinical outcome after percutaneous coronary intervention. We evaluated 204 patients who fulfilled the study criteria and were scheduled for elective percutaneous coronary intervention. The patients were divided into a metabolic syndrome group and a control group according to ...
Xia Michelle M *Department of Pathology, University of Texas Medical Branch, Galveston, TX; and †South Coast Forensics, - - 2014
Boerhaave syndrome is an uncommon condition with high rate of mortality that is higher than 90%. The syndrome has classically been associated with sudden severe chest pain after severe emesis or retching. However, traumatic esophageal rupture secondary to blunt injury has been occasionally reported in the literature, usually from unintentional ...
Romero-Valdovinos M M Departamento de Biología Molecular e Histocompatibilidad, Hospital General "Dr. Manuel Gea González", Secretaría de Salud, - - 2014
The etiology of the amniotic band syndrome is unknown, and has been subject of debate since the time of Hippocrates. The most accepted theories fail to cover all the abnomalities found in affected children. During organogenesis the epithelial-mesenchymal transition process (EMTP) participates in adequate formation of different organs from three ...
Walter James M JM Department of Internal Medicine, San Francisco Veterans Affairs Medical Center, University of California San Francisco, 4150 Clement St, San Francisco, CA 94121, - - 2014
Acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by alveolar flooding with protein-rich pulmonary edema fluid. Despite an improved understanding of ARDS pathogenesis, our ability to predict the development of ARDS and risk-stratify patients with the disease remains limited. Biomarkers may help identify patients at highest risk of ...
Jing-Chun Zhao Z From the Burns and Plastic Reconstruction Unit, The First Hospital of Jilin University, Changchun, - - 2014
Literature on the complications of burns is abundant. However, there is a paucity of literature on Parsonage-Turner syndrome as a complication of contact burns. The authors describe the case of a 27-year-old Chinese man who sustained contact burns on the left upper limb and the left side of the chest ...
Fu Yuyang Y Vascular Biology and Therapeutics Program, Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas; Department of Cardiovascular Surgery, Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, - - 2014
Metabolic syndrome is now an epidemic in the United States population. Intimal hyperplasia remains the principal lesion in the development of restenosis after vessel wall injury. The aim of this study is to characterize the changes induced in wall morphology in the developing intimal hyperplasia within a murine model in ...
Gan Changping C Department of Cardiovascular Surgery. West China Hospital, Sichuan University, Chengdu, Sichuan, P. R., - - 2014
Poland syndrome and Gerbode-type defect are both very rare congenital malformations. A combination of them is extremely uncommon and no literature has reported before. We herein present a case of this combination in a 9-year-old boy. Besides the reconstruction of the chest wall, a device closure of the Gerbode-type defect ...
Poretti Andrea A Department of Pediatric Neurology, University Children's Hospital, Zurich, Switzerland; Section of Pediatric Neuroradiology, Division of Pediatric Radiology, Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, - - 2014
Head thrusts are well documented in Joubert syndrome and ocular motor apraxia. We provide a detailed clinical characterization of head titubation in 13 young children with Joubert syndrome. Detailed characterization of head titubation was assessed by targeted clinical evaluation and/or analysis of videos. In 12 of 13 children (eight males, ...
Rai Birendra B 1Midland Regional Hospital, Mullingar Westmeath, - - 2014
We present a case of a 1-year-old female child who was referred to the Early Intervention Clinic for evaluation of developmental delay and progressively enlarging head size. Developmental assessment revealed significant motor delay with borderline cognitive impairment. MRI of the brain revealed generalized ventriculomegaly secondary to narrowing of the spinal ...
McLaughlin Nancy N Nancy McLaughlin is an assistant program director of the PA program at the Philadelphia (Pa.) College of Osteopathic Medicine. Hank Heard is an assistant clinical professor in the PA program at Mercer University in Atlanta, Ga. Steven Kelham is a chief PA at Forsyth Street Orthopaedics in Macon, Ga., assistant team physician for Mercer University athletics, and a clinical preceptor in orthopedics in the Mercer University PA program. The authors have disclosed no potential conflicts of interest, financial or - - 2014
Compartment syndrome is a fairly common condition noted in patients with fractures or crush injuries to the extremities(acute compartment syndrome) and in athletes (chronic compartment syndrome). Compartments bound by fascia are found in the extremities, buttocks, and abdomen; conditions that cause intracompartmental swelling and hypertension can lead to ischemia and ...
Kalantzis George G Ophthalmology Department, St. James University Hospital , Leeds, UK ; Ophthalmology Department, Athens General Hospital , Athens, - - 2014
The presentation of Horner's syndrome following blunt trauma is uncommon, but is of important clinical significance. Identification of the constellation of signs of Horner's syndrome should, therefore, prompt urgent neuro-radiologic imaging. Early diagnosis and initiation of appropriate treatment can lead to excellent outcomes in the majority of cases and prevent ...
Borlot Felippe F From the Instituto da Criança (F.B., C.A.K.), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HC FMUSP) (F.B., C.A.K., P.R.A., A.C.C.C.), - - 2014
Morquio A syndrome (Online Mendelian Inheritance in Man #253000) is a lysosomal storage disease caused by deficiency of N-acetylgalactosamine-6-sulfatase encoded by the GALNS gene. Key clinical features are skeletal dysplasia and short stature.
Bodart Olivier - - 2014
Predicting recovery of consciousness in patients who survive their coma but evolve to a vegetative state (recently coined unresponsive wakefulness syndrome) remains a challenge. Most previous prognostic studies have focused on the acute coma phase. A novel outcome scale (combining behavioural, aetiology, electroencephalographic, sleep electroencephalographic and somatosensory evoked potential data) ...
Xu Aibin A Departments of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, People's Republic of China; Institute of Cardiovascular Disease, General Hospital of Beijing Command, PLA, Beijing, People's Republic of - - 2014
Metabolic syndrome is a major risk factor for cardiovascular diseases, and increased cardiomyocyte apoptosis which contributes to cardiac dysfunction after myocardial ischemia/reperfusion (MI/R) injury. Nur77, a nuclear orphan receptor, is involved in such various cellular events as apoptosis, proliferation, and glucose and lipid metabolism in several cell types. Apoptosis is ...
Gauthé Mathieu M Institut Curie, Department of Nuclear Medicine, 35rueDailly, F-92210, Saint-Cloud, - - 2014
Sinusoidal Obstruction Syndrome (SOS) is a potentially fatal liver injury that mainly occurs after myeloablative chemotherapy. We report two cases of SOS investigated by 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and treated with defibrotide. (Hepatology 2014;).
Sharpless Brian A BA Department of Psychology, Washington State University, 364 Johnson Tower, Pullman, WA 99163, USA. Electronic address: - - 2014
Exploding head syndrome is characterized by the perception of abrupt, loud noises when going to sleep or waking up. They are usually painless, but associated with fear and distress. In spite of the fact that its characteristic symptomatology was first described approximately 150 y ago, exploding head syndrome has received relatively ...
Murata Yasuaki Y Department of Orthopaedic Surgery, Tokyo Women's Medical University, Tokyo, Japan. Electronic address: - - 2014
A few reports have addressed tethered cord syndrome. Detethering surgery has been performed in these cases because abnormal tension on the spinal cord causes neurological and urological symptoms.  To discuss the surgical treatment of tethered cord syndrome with the belief that the tension on the cord can be decreased by ...
Ye Bei B Department of Gastroenterology, Taizhou Municipal Hospital, Taizhou, Zhejiang, - - 2014
We report a case of a patient with a delayed large intrahepatic hematoma and transient decline in hemoglobin to 62 g/L 18 days after liver injury. Abdominal computed tomography revealed seriously flattening of inferior vena cava, which was consistent with compression by the enlarging hematoma. Although traditionally there was no ...
Cuff Patricia P From the Institute of Medicine (P.C.), Washington, DC; University of Pennsylvania School of Nursing (A.M.), Philadelphia; and George Washington University and the Association of American Medical Colleges (J.C.), Washington, - - 2014
Since 2009, a mysterious neurologic condition has afflicted thousands of northern Ugandan school children. This fatal disorder-known as nodding disease-leaves its victims stunted, mentally incapacitated, and often severely scarred or burned due to unexpected falls from epileptic-like seizures.(1,2) The syndrome is characterized initially by cognitive impairments followed by frequent head-nodding ...
Fard Nassim N Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, - - 2014
Acute respiratory distress syndrome (ARDS) is a common critical pulmonary complication after esophagectomy and other thoracic surgeries (e.g., lung transplantation, pulmonary thromboendarterectomy). Direct pulmonary ischemia-reperfusion injury (PIRI) is known to play the main role in induction of ARDS in these cases. Large animal models are an appropriate choice for ARDS ...
Kauther Max Daniel MD Department of Trauma Surgery, University of Duisburg-Essen, Hufelandstraße 55, 45147, Essen, Germany, - - 2014
Wheel gymnastics is a gymnastic discipline with a history of nearly 100 years. So far, there have been no epidemiological studies on injuries in wheel gymnastics. The retrospective study of wheel gymnasts surveyed 151 "professionals" competing in the first national league and 352 "amateurs" by questionnaire. 4,898 injuries and 714 overuse ...
Wardi Gabriel G Department of Emergency Medicine, UC San Diego Health System, San Diego, - - 2014
Thigh compartment syndrome is a rare and devastating process. It generally occurs within hours to days of a traumatic event, although cases have been reported nearly 2 weeks after the initial event. To evaluate the literature describing the timing between inciting event and presentation of thigh compartment syndromes, with a ...
Tian Xuefei - - 2014
Podocytes are specialized actin-rich epithelial cells that line the kidney glomerular filtration barrier. The interface between the podocyte and the glomerular basement membrane requires integrins, and defects in either α3 or β1 integrin, or the α3β1 ligand laminin result in nephrotic syndrome in murine models. The large cytoskeletal protein talin1 ...
Gill James R JR State of Connecticut, Office of the Chief Medical Examiner, 11 Shuttle Rd, Farmington, CT, 06032, USA, - - 2014
The excited delirium syndrome (EDS) is a life-threatening condition caused by a variety of factors including drug intoxication and psychiatric illness. Fatal instances of excited delirium frequently come to the attention of the medical examiner/coroner due to the circumstances and potential causes. Excited delirium may include paranoid, aggressive, and incoherent ...
Coban Yusuf Kenan YK Yusuf Kenan Coban, Burn Unit and Department of Plastic Surgery, Inonu University Turgut Ozal Medical Centre, 44280 Malatya, - - 2014
Rhabdomyolysis (RML) after electrical burns and crush injuries is a well-known clinical entity, but its occurrence following thermal injury has not gained so much attention. Capillary leak syndrome and following polycompartmental syndrome are devastating end results of major thermal injuries. In the current review, polycompartment syndrome within the clinical picture ...
Pintado M C MC Unidad de Cuidados Intensivos, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España. Electronic address: - - 2014
Current treatment of acute respiratory distress syndrome is based on ventilatory support with a lung protective strategy, avoiding the development of iatrogenic injury, including ventilator-induced lung injury. One of the mechanisms underlying such injury is atelectrauma, and positive end-expiratory pressure (PEEP) is advocated in order to avoid it. The indicated ...
Noris Marina M IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Clinical Research Centre for Rare Diseases "Aldo e Cele Daccò", via Camozzi 3, 24020 Ranica, Bergamo, - - 2014
Haemolytic uraemic syndrome (HUS) is characterized by nonimmune haemolytic anaemia, thrombocytopenia and renal impairment-most incidents in childhood are caused by shiga toxin-producing bacteria. Atypical HUS (aHUS) accounts for 10% of cases and has a poor prognosis. About 60% of patients with aHUS have dysregulation of the alternative complement pathway (complement-mediated ...
Xu Lingjie L Department of Emergency Medicine, Peking Union Medical Collage Hospital, Peking Union Medical Collage , Beijing , China - - 2014
Abstract Paraquat is an organic heterocyclic herbicide that is widely used in agriculture, especially in Asian countries. The prevalence of paraquat poisonings has increased dramatically in the past two decades in China. Nearly all paraquat poisonings resulted from intentional or accidental oral administration leading to acute lung injury and, ultimately, ...
Wu Jun-Biao JB Department of Pharmacology, College of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, PR - - 2014
Nephrotic syndrome (NS) is a clinical syndrome with a variety of causes, mainly characterized by heavy proteinuria. Podocyte injury plays a key role in proteinuria, one of the principal means for the control of NS is to prevent podocyte injury. Qi-Dan Fang consists of two of the most extensively applied ...
Sutamtewagul Grerk G Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, - - 2014
"Bath salts" is a well known street drug which can cause several cardiovascular and neuropsychiatric symptoms. However, only one case of acute kidney injury has been reported in the literature. We present a case with sympathomimetic syndrome, choreoathetosis, gustatory and olfactory hallucinations, and acute kidney injury following the use of ...
Pavan Malleshappa M Division of Nephrology, Department of Medicine, Adichunchanagiri Institute of Medical Sciences, B G Nagara, Karnataka, India. - - 2014
Introduction. The aim of this study was to determine the incidence of acute renocardiac syndrome (cardiorenal syndrome type 3) and its outcome in a suburban population in India. Materials and Methods. In an observational study, 100 patients admitted with acute kidney injury were evaluated. Results. Acute renocardiac syndrome was documented ...
Engelhardt Eliasz E Instituto de Neurologia Deolindo Couto, Centro para Doença de Alzheimer, Instituto de Psiquiatria, Universidade Federal do Rio de Janeiro, Rio de JaneiroRJ, - - 2014
Brown-Séquard, a remarkable medical personality of the 19 th century, was born in a small island of the Indian Ocean. He travelled over the world exerting his skills: a successful physician, and an innovative researcher, with a very ample range of interests. His favored subject was the nervous system. The ...
Aparecida da Silva Crislaine C Pathology Laboratory, Nephropathology Service, Federal University of Triângulo Mineiro, 38015-150 Uberaba, MG, - - 2014
Focal segmental glomerulosclerosis (FSGS) is a glomerulopathy associated with nephrotic syndrome and podocyte injury. FSGS occurs both in children and adults and it is considered the main idiopathic nephrotic syndrome nowadays. It is extremely difficult to establish a morphological diagnosis, since some biopsies lack a considerable quantifiable number of sclerotic ...
Davis Matthew C - - 2014
In this editorial, the value of hyperbaric oxygen therapy in the management of chronic post-concussive syndrome following mild traumatic brain injury is discussed.
Naeini Alireza E AE Infectious and Tropical Diseases Department, Isfahan University of Medical Sciences, Isfahan, - - 2014
Vogt-Koyanagi-Harada (VKH) is a rare syndrome affecting tissues containing melanocytes. The possibility of its autoimmune pathogenesis is supported by high frequent HLA-DR4 presentation, commonly associated with other autoimmune diseases. Eyes are the main affected organs, resulting in blindness. Brain disease is a late-onset event, and is extremely rare. Here, we ...
Bucak Abdulkadir A Department of Otolaryngology, Faculty of Medicine, Afyon Kocatepe University, Ali Cetinkaya Kampusu, Tıp Fakultesi Izmir Karayolu, 03200 Afyonkarahisar, - - 2014
Grisel's syndrome is a nontraumatic atlantoaxial subluxation which is usually secondary of an infection or an inflammation at the head and neck region. It can be observed after surgery of head and neck region. Etiopathogenesis has not been clearly described yet, but increased looseness of paraspinal ligament is thought to ...
Alawadhi Feryal F Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut, United States of - - 2014
Asherman's Syndrome is characterized by intrauterine adhesions or fibrosis resulting as a consequence of damage to the basal layer of endometrium and is associated with infertility due to loss of normal endometrium. We have previously shown that bone marrow derived stem cells (BMDSCs) engraft the endometrium in mice and humans ...
Al-Hassani Fawaz F Department of Plastic Surgery, Queen Victoria Hospital, East Grinstead, - - 2014
Oxyacetylene welding torches are commonly used in industry, yet serious burns are fortunately rare. When dealing with the sequelae of these burn injuries, one must be aware of the high pressure component of these flame burns, which can penetrate and dissect the subcutaneous tissue. Appropriate initial assessment and preoperative planning ...
Omalu Bennet B University of California, Davis, Medical Center, Sacramento, Calif., and San Joaquin General Hospital and San Joaquin County Coroner's Division, French Camp, Calif., - - 2014
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative syndrome, which is caused by single, episodic, or repetitive blunt force impacts to the head and transfer of acceleration-deceleration forces to the brain. CTE presents clinically as a composite syndrome of mood disorders and behavioral and cognitive impairment, with or without sensorimotor ...
Donaldson James J Holland Orthopaedic and Arthritic Centre, Toronto, - - 2014
Acute compartment syndrome (ACS) is a surgical emergency warranting prompt evaluation and treatment. It can occur with any elevation in interstitial pressure in a closed osseo-fascial compartment. Resultant ischaemic damage may be irreversible within six hours and can result in long-term morbidity and even death. The diagnosis is largely clinical ...
Ahmed Gasim Salaheldin GS Department of Medicine, University of Limerick Hospital Nenagh, Nenagh, - - 2014
An otherwise healthy young man presented with gradual progressive fatigue for the past 12 months disturbing his daily activities. Clinical examination revealed marked generalised muscular hypertrophy including the temporalis muscles bilaterally. Investigation revealed that the patient was grossly hypothyroid due to Hashimoto's thyroiditis with rhabdomyolysis and acute kidney injury. The finding ...
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