Breath hydrogen production after oral lactose loading was examined in infants and children with stagnant loop syndrome, blind loop syndrome, or both. All six infants under 3 years of age had bacteriological evidence of small intestinal colonization. The characteristics of the breath hydrogen test in this syndrome are: (a) extremely ...

A case of acute small bowel obstruction is presented occurring five months after blunt abdominal trauma due to a seat-belt injury. The problem of early diagnosis is discussed. With the increasing use of seat-belts, clinicians should be aware of this condition as part of the 'Seat-Belt Syndrome'. Histopathology of the ...

Four patients with the Ruvalcaba-Myhre-Smith syndrome (primary macrocephaly with associated anomalies including pigmented macules on the penis in affected males, hamartomatous intestinal polyps, and lipomas) had evidence of delayed psychomotor development and/or hypotonia in childhood. Electromyography in 3 patients showed evidence of a myopathic process. Muscle biopsy in all four ...

Myasthenic syndrome secondary to small cell lung cancer has been studied in five patients who achieved complete remission with chemotherapy. The relationship between response or relapse of the neoplasm to therapy and the activity of the myasthenic syndrome is variable. This inconsistent clinical correlation between the cancer and its paraneoplastic ...

Two siblings are presented in whom a recognized syndrome of functional small-bowel obstruction with malrotation and short small-bowel was diagnosed. The previously described association with pyloric stenosis was not present in our cases. They do, however, support the view that this syndrome has an autosomal recessive model of inheritance. A ...

Small viral particles of 19 to 24 nm in diameter with a buoyant density in CsCl of 1.43 g/ml were detected electron microscopically in samples taken from the gut of 10-day-old chickens suffering from a stunting syndrome. The viral particles are suggested to belong to the Parvoviridae and their possible ...

The mucosa of the upper small intestine in humans is repeatedly exposed to potentially harmful environmental influences: infective, toxic and antigenic. One of the most significant manifestations of the control over environmental risks is how the upper intestinal milieu is kept relatively sterile and pathogen-free despite constant exposure to a ...

The ultrasonographic finding of small bowel polyps is reported in a 16-year-old girl, referred for evaluation of abdominal pain. The sonographic study was of particular value in also excluding pregnancy and in documenting small bowel obstruction. We have found that distended small bowel and its contents are accessible to sonographic ...

The sensitivity of human erythrocytes to photohemolysis sensitized by addition of protoporphyrin IX can be selectively affected by their enrichment with substances carried by cationic liposomes. In particular the enrichment which superoxide dismutase is accompanied by a copper-related greater sensitivity toward photohemolysis, as observed in the Down's syndrome (mongolism). Instead ...

A syndrome of dysarthria following the appearance of small left frontal-lobe lesions has been recognized for many years but identified by numerous labels. Varied terminology has led to confusion in the literature and inadequate recognition of this syndrome as a distinctive clinical entity. We gathered clinical and anatomic (computed tomographic) ...

A 28-year-old Iranian man with chronic idiopathic intestinal pseudo-obstruction presented with gross features of contaminated bowel syndrome. Treatment with metronidazole reversed steatorrhea but exacerbated the gaseous distention of the small intestine, precipitating emergency surgical decompression and ileostomy. A chronic high volume ileostomy diarrhea ensued and was successfully treated with oral ...

Short-bowel syndrome results in malabsorption and malnutrition producing profound metabolic disorders. Attempts to correct this problem with various surgical procedures have so far proved unsuccessful. Studies made in our laboratory using experimental animals, showed that a modified jejunocolic intussusception valve appears to be effective in prolonging the small-bowel transit time ...

The authors describe a transendoscopic wire snare excision of three jejunal polyps in a patient with Peutz-Jeghers syndrome. Two years previously the patient had undergone surgical jejunal segmental resection for invagination caused by several polyps, one of which revealed carcinoma in situ. The procedure was well tolerated, and the subsequent ...

The mesourachus is an uncommon anomaly in which the urachal remnant is connected with the anterior abdominal wall by a well-defined mesentery. Likewise, large-bowel obstruction secondary to adhesions and/or congenital bands is very rare in both adults and children. In the following case report of an 8-year-old boy with trisomy ...

A 52-year-old Black man with therapy-resistant parkinsonism, gait apraxia and dementia but no endocrine abnormality was found to have extensive intracerebral calcifications which included the basal ganglia. Although most patients with radiological evidence of calcifications in the basal ganglia remain asymptomatic, a small group may present with an extrapyramidal syndrome ...

Duplication of the entire small intestine resulting in gastrointestinal hemorrhage was managed by excision of the ulcerogenic lesion, ileo-ileostomy, and diversion of the gastric-lined intestinal duplication into the stomach. A 25 yr followup study reveals no evidence of recurrent bleeding or malabsorption secondary to bind-loop syndrome. This operative procedure is ...

Short bowel syndrome is a complex disease that is almost always seen with diarrhea. VIP is known to act powerfully on gut motility, and elevated VIP plasma levels have been reported in several diarrheal conditions. In this study VIP plasma levels were measured by radioimmunoassay in 8 patients with short ...

Two newborn infants with megacystis-microcolon-intestinal hypoperistalsis syndrome are described. Review of the literature revealed twenty previously reported cases of this syndrome. Electron microscopic examination of the ileum and urinary bladder showed vacuolar degenerative changes in the smooth muscle cells with abundant amount of connective tissue between the muscle cells. These ...

The Gardnerella vaginalis syndrome (GVS) is characterized by a smelly vaginal discharge of pH greater than 5.2. The microscopic appearance of the discharge is diagnostic. The Gram stain shows masses of small Gram variable bacilli which have a 'pepper and salt' pattern, and the wet film 'clue cells' and 'rafts' ...

A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) is presented. There were important findings: a urachal remnant and a brother with prune belly syndrome (PBS). After a review of the literature, many common characteristics of MMIHS and PBS are described: flaccid abdomen, dilatation of the urinary tract, intestinal malrotation, cryptorchidism, urachal ...

Microbasic p-mastigophores, euryteles of two size groups, holotrichous isorhizas and atrichous isorhizas, comprise the cnidom of Chironex fleckeri, a cubozoan that has been responsible for several human fatalities. In its undischarged state each microbasic mastigophore of C. fleckeri consists of a capsule containing matrix and an inverted tube possessing a ...

This case report of a patient with a large Meckel's diverticulum with associated stagnation and bacterial proliferation demonstrates the resultant metabolic and nutritional alterations that have classically been described with the blind loop syndrome. A lesion as large as the one presented herein has rarely been reported with iron, vitamin ...

Brownish discoloration of the muscular layers of the small intestine has been described in association with deficiency of fat soluble vitamin E occurring in various disorders with malabsorption. A patient presenting with diarrhea ultimately found to have "brown bowel syndrome" is reported with serum levels of vitamin E before and ...

The Gardnerella vaginalis syndrome is a well defined but benign condition characterized by a smelly vaginal discharge of pH greater than 5.0. It is not associated with inflammation. It often occurs in association with cervical infections. The microscopic appearance of the discharge is typical and diagnostic. The wet mount shows ...

The case history of a six-year-old female chow chow with intractable diarrhoea is described. The clinical history and symptoms, together with the methods of diagnosis, indicated that the cause was bacterial overgrowth of the intestine leading to a malabsorption syndrome. The method of treatment and the response is also recorded.

Recent reports indicate that circulating IgA immune complexes may play a primary role in the pathogenesis of Henoch-Schönlein vasculitis and are responsible for the granular deposits of IgA seen in biopsy specimens of skin and kidney. A patient had classic Henoch Schönlein syndrome, including hematuria, purpura, and abdominal pain; tissue ...

Posterior gastropexy appears to be the treatment of choice in the occasional patient with persistent debilitating post-fundoplication syndrome. This syndrome occurs to this extent only rarely (less than 1%) and chronic small-bowel obstruction or dysfunction may be a predisposing factor. We prefer the posterior gastropexy of Hill in cases of ...

The development of the bacterial flora of neonates with congenital abnormalities of the gastro-intestinal tract was studied in 31 infants during the first 10 days of life. Specimens were collected from the umbilicus, mouth and gastro-intestinal tract on the pre-operative day, at operation and on post-operative days 1, 2, 3, ...

The number and sizes of myelinated and unmyelinated fibers in biopsied sural nerves in cases with Shy-Drager syndrome were studied in comparison with cases with olivopontocerebellar degeneration not having autonomic dysfunction. In Shy-Drager syndrome there was a tendency for both small myelinated and unmyelinated fiber densities to be reduced in ...

This study describes the prevalence, distribution, pathology and pathogenesis of lumbar interspinous bursitis (described as a clinical syndrome by Baastrup in 1933). It is based on an anatomic study of 152 lumbar spines derived from routine and random postmortem material, together with selected specimens from autopsies on patients with various ...

A 70-year-old man developed symptoms compatible with the Eaton-Lambert syndrome, and a small cell bronchogenic carcinoma was diagnosed. During treatment with cytostatics his muscular strength was restored and the lung tumour as well as the electrophysiologic findings characteristic of the Eaton-Lambert syndrome disappeared. To our knowledge, it has not been ...

The value of an interposed antiperistaltic colon segment in the management of short-bowel syndrome was assessed in four adult dogs. Following 90 per cent small-bowel resection, and an interposition of 20-cm length of antiperistaltic colon segment, several parameters of small-bowel function were measured. These included regular serum chemistries, including serum ...

In five dogs, the abroad two-thirds of the small intestine were removed, and a jejunocolostomy was performed to create the short bowel syndrome. Electrodes were affixed to the remaining proximal part of the small intestine for recording and to the distal part of the small intestine for stimulating. A comparison ...

An infant girl with the megacystis microcolon intestinal hypoperistalsis syndrome is reported. The presence of polyhydramnios and the absence of upper urinary tract abnormalities, differentiate this patient from similar cases previously reported. Although the etiology of this disease is unknown, partial success with the use of bethanechol suggests that the ...

Several reports have recently suggested an association between the development of intestinal carcinoma and the presence of Peutz-Jeghers syndrome. During the 45-year period between 1935 and 1979, 48 patients with Peutz-Jeghers syndrome were seen at the Mayo Clinic, Rochester, Minn, and followed up for a median period of 33 years. ...

The absence of sensory adaptations in patients who have an esotropia of 12 to 18 degrees constitutes what has been described as the blind spot syndrome. Here, the physiological blind spot is said to provide the means of avoiding diplopia and confusion. The small size of the optic disc and ...

Twenty-two patients with Henoch-Schonlein syndrome are reviewed, and four unusual cases are reported in detail. Henoch-Schonlein syndrome represents a diagnostic problem when abdominal manifestations precede cutaneous lesions and suggest a surgical abdomen. Unusual radiographic features such as changes in the small bowel identical to Crohn disease or colonic involvement may ...

Two patients hyperinfected with Strongyloides stercoralis (an intestinal nematode) are described. Both were both in Puerto Rico and had left the island six to 15 years previously; both were receiving adrenal steroids (one for Hodgkin's disease and the other for Goodpasture's syndrome). One died shortly after diagnosis, but the other ...

Small bowel bypass procedures for morbid obesity have been associated with many postoperative complications. With the use of the Scott procedure, the bypassed or excluded small bowel segment has recently been the focus of 2 syndromes -- "bypass enteritis' and "defunctioned bowel syndrome'. We describe these postoperative complications and present ...

Metabolic acidosis in a 3-year-old child with short bowel syndrome led to the discovery of massive D-lactic aciduria. After normalisation of the intestinal bacterial flora, D-lactate disappeared together with the acidosis. Dysbacteriosis with excessive production of D-lactate by intestinal bacteria (unidentified) and subsequent absorption explains this unusual cause of metabolic ...

The correction of the dumping syndrome is based on three surgical techniques: narrowing of the gastrojejunal for gastroduodenal) anastomosis, interposition of an intestinal loop between the gastric stump and the duodenum, or conversion of Billroth II to Billroth I. The authors report the results obtained in a series of 22 ...

In some instances, particularly in the neonate, paralytic ileus affects predominantly the small bowel, thus resembling intestinal obstruction. Localized paralysis of the small bowel occurs secondary to regional events in a segment of gut and resembles mechanical obstruction even more closely. In localized paralysis the bowel lumen is usually dilated ...

A case of small bowel obstruction caused by inflation of a sealed, mercury-filled finger cot tipped feeder catheter, used for enteral alimentation, is reported. The patient had infrapapillary duodenal obstruction, secondary to the intramural hematoma caused by blunt abdominal injury. The patient underwent surgery for the obstruction and the distended ...

Thirteen cases classified in our files as ceroid pigmentation of the intestinal wall ("brown bowel syndrome") are described. Clinically, all patients in this series had some symptoms of chronic bowel disease. The gut in this condition grossly demonstrates a variable orange-brown coloration. The ceroid pigment is difficult to identify in ...

We report for the first time from Malaysia a patient with Peutz-Jeghers syndrome complicated by successive intussusceptions requiring extensive small bowel resection. Our experience is compared with that of other authors by a review of the literature highlighting important points in the diagnosis and management of complications in Peutz-Jeghers syndrome.

Children with a Monofixation syndrome often show a small angle constant esotropia with an overlying esophoria of variable and often large angle. Commonly the phoria is well controlled unless the child is very tired, or the eyes are dissociated. Treatment of a concomitant amblyopia by patching may result in an ...

Leprechaunism is a rare syndrome of unknown etiology. As only 9 conclusive examples of the syndrome have been reported, it seems useful to add the present case to the literature. This congenital deformity produces a small, grossly hirsute, grotesque infant who usually fails to thrive and survives only a matter ...

Prostaglandins and serotonin are vasoactive compounds with profound effects on the gastrointestinal tract. Both cause inhibition of gastric acid secretion (although serotonin stimulates gastric pepsin secretion), stimulation of intestinal motility, and conversion of small intestinal mucosa from absorption to secretion of water and electrolytes. Their effects on pancreatic and biliary ...

An unusual late complication of side-to-side intestinal anastomosis, chronic small-bowel obstruction with massive proximal ileal dilation despite a widely patent anastomosis, occurred in a patient. The classic blind loop syndrome was not present. Several potential mechanisms are suggested, including regional absence of normal peristalsis on a mechanical basis and bacterial ...

The dermatoglyphics of seven patients with Rubinstein-Taybi syndrome and their seventeen family members were compared with those of 250 male and 250 female controls. The most striking dermatoglyphic findings of the patients were the increased frequency of arches, decreased frequency of ulnar loops and reduced ridge-counts on the finger-tips, particularly ...