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Steveling Esther Helen EH Clinic of Internal Medicine, University Hospital Basel, Basel, - - 2014
Background: The occurrence of both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) in an individual patient has been described as 'overlap syndrome', which has been associated with poor prognosis. Little is known about the possible predictors of the overlap syndrome and its association with comorbidities contributing to ...
Azhar A A Department of Pediatric Cardiology, Faculty of Medicine, King Abdulaziz University, P. O. Box 80260, Jeddah, 21589, Kingdom of Saudi Arabia, - - 2014
Pentoxifylline is a well-tolerated drug used in treatment of vascular insufficiency. We previously showed that pentoxifylline protects from impairment in vascular reactivity in cases of metabolic syndrome. The aim of this study was to investigate the protective effect of pentoxifylline against hypertension in metabolic syndrome rats. Metabolic syndrome was induced ...
Isidori Andrea M AM aDepartment of Experimental Medicine, Sapienza University of Rome bUnit of Endocrinology, Università Cattolica del Sacro Cuore, Rome cDipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Università Federico II di Napoli, Naples dNeuroendocrinology Research Laboratory, Istituto Auxologico Italiano IRCCS, Milan, - - 2014
Cushing's syndrome is associated with increased mortality, mainly due to cardiovascular complications, which are sustained by the common development of systemic arterial hypertension and metabolic syndrome, which partially persist after the disease remission. Cardiovascular diseases and hypertension associated with endogenous hypercortisolism reveal underexplored peculiarities. The use of exogenous corticosteroids also ...
Ciemniewska-Gorzela Kinga - - 2014
Intra-abdominal hypertension and abdominal compartment syndrome have been increasingly recognized as a hip arthroscopy complication over the past decade. In the absence of consensus definitions and treatment guidelines, the diagnosis and management of intra-abdominal hypertension and abdominal compartment syndrome remains variable from institution to institution. We report the occurrence of ...
Tang Yizhe Y Department of Molecular Pharmacology, Diabetes Research Center, Institute of Aging, Albert Einstein College of Medicine, New York, NY 10461, - - 2014
Chronic microinflammation is a hallmark of many aging-related neurodegenerative diseases as well as metabolic syndrome-driven diseases. Recent research indicates that chronic caloric excess can lead to hypothalamic microinflammation, which in turn participates in the development and progression of metabolic syndrome disorders such as obesity, glucose intolerance, and hypertension. Additionally, it ...
Kovanen Leena L Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare (THL), Helsinki, - - 2014
The circadian clock affects metabolic cycles, and there is a link between circadian clock genes and metabolic syndrome. Therefore, we wanted to investigate whether variants of the core circadian clock genes, cryptochrome circadian clocks 1 and 2 (CRY1 and CRY2), or those of protein kinase C, delta binding protein (PRKCDBP), ...
Alp Alper - - 2014
Hypertension (HT) represents a major public health problem affecting many individuals worldwide. It is well known to be an important risk factor for the development of cerebrovascular and cardiovascular diseases. Classifying hypertension as ‘primary’ or ‘secondary’ depends on the underlying mechanism. In 5 to 10% of hypertensive patients, HT develops ...
Borkar Vibhor V VV Departments of Pediatric Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, - - 2014
Hepatopulmonary syndrome in children has not been extensively studied particularly in different subsets of portal hypertension. We prospectively studied hepatopulmonary syndrome in children with cirrhosis and extrahepatic portal venous obstruction. Their comparison might shed light on the pathogenesis of hepatopulmonary syndrome. Between 1 to 18 years of age, 135 children ...
Ohta Toshiyuki T Department of Pediatric Nephrology, Hiroshima Prefectural Hospital, 1-5-54 Ujina-Kanda, Minami-ku, Hiroshima city, Hiroshima, 734-8530, Japan, - - 2014
Severe hypertension (HTN) and acute kidney injury frequently associated with atypical hemolytic uremic syndrome (aHUS) were refractory to various therapies in the pre-eculizumab era. Here we report the case of a 4-month-old boy who developed aHUS presenting with undetectable C3 protein, no predisposing mutations in complement factors, and no antibodies ...
Coufal Z Z Cardiology Department T. Bata Regional Hospital, Inc. Zlin, Czech Republic - - - 2014
The case involved a 75-year-old male patient whose risk factors included hypertension, diabetes (on oral treatment) and untreated hypercholesterolaemia. He was previously admitted to the urology department in 2012 due to severe haematuria and was referred to transvesical prostatectomy. His condition became progressively complicated by acute coronary syndrome.
Pradeep A V AV Department of Ophthalmology, Sri Dharmasthala Manjunatheshwara College of Medical Sciences, Manjushree Nagar, Sattur, Dharwad 580009, Karnataka, - - 2014
Peripartum vision loss, an uncommon, often reversible complication of pregnancy usually occurs in the setting of pre-eclampsia or eclampsia. The HELLP syndrome is characterized by hypertension, elevated liver enzymes and low platelets. This is a rare case of unilateral exudative retinal detachment associated with the Partial HELLP syndrome that occurred ...
Fjouji Salaheddine - - 2014
Demons-Meigs' syndrome is characterized by the presence of a benign ovarian tumor associated with ascites and a right-sided hydrothorax. Its pathophysiology remains unclear. Anesthesia of this syndrome is a real challenge. Respiratory, hemodynamic, metabolic problems and abdominal hypertension are the main anesthetic risks. A 52-year-old African woman with Demons-Meigs' syndrome ...
Licata Anna A Sezione di Gastroenterologia & Epatologia, Dipartimento Biomedico di Medicina Interna e Specialistica, DIBIMIS, Università di Palermo, Palermo, - - 2014
The hyperdynamic syndrome is a late consequence of portal hypertension in cirrhosis. The principal hemodynamic manifestations of the hyperdynamic syndrome are high cardiac output, and increased heart rate and total blood volume, accompanied by reduced total systemic vascular resistance. Pathophysiology involves a complex of humoral and neural mechanisms that can ...
Kumar Bharat B University of Kentucky, Lexington, KY - - 2014
A 59-year-old man with hypertension and Crohn's disease that was complicated by fistulas was found unconscious at home. He was intubated and brought to the emergency department. Venography showed occlusion of the superior vena cava.
Bloom Stephen S Gastroenterology and Hepatology, Eastern Health, Melbourne, Victoria, - - 2014
Portal hypertension is an important complication of liver disease, although other conditions may also be implicated. As a result of elevated pressures within the portal vein a number of complications can arise including the development of oesophageal and gastric varices, ascites, hepatic encephalopathy as well as complications secondary to circulatory ...
Yamane Takuya T Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo 060-0812, Japan. Electronic address: - - 2014
DJ-1 is a protein that is associated with Parkinson disease and cancer, and the reduction of DJ-1 function and expression is also thought to be a cause of diabetes and hypertension. However, little is known about the association between the plasma concentration of DJ-1 and risk of metabolic syndrome. We ...
Adikari Madura - - 2014
Posterior reversible encephalopathy syndrome is a clinical radiographic syndrome of heterogeneous etiologies. Developing hypertensive encephalopathy following post-streptococcal glomerulonephritis is a known but uncommon manifestation and developing posterior reversible encephalopathy syndrome in such a situation is very rare. We report a case with contrast-enhanced computed tomography and magnetic resonance imaging findings ...
Saad Wael E WE Department of Radiology, University of Michigan Medical Center, Ann Arbor, - - 2014
The term "portosystemic shunt syndrome" was coined by Kumamoto et al referring to reduction of the hepatic reserve (reflected by progression of the Child-Pugh score) over 5 years compared with portal hypertensive cirrhotics without gastrorenal shunts or with prior history of obliterated gastrorenal shunts. Saad et al elaborated on this ...
Veskitkul J J Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
We herein report a case of antiphospholipid syndrome (APS) primarily presenting with asthma-like symptoms that had been misdiagnosed as severe asthma. Patients presenting with severe asthma symptoms along with systemic thrombosis should be systematically evaluated for APS. Pediatr Pulmonol. © 2014 Wiley Periodicals, Inc.
Samra Tanvir T Department of Anaesthesia and Intensive Care, Lady Hardinge Medical College, New Delhi, - - 2014
A 15-year-old boy with Noonan's syndrome was admitted for emergency ventriculo-peritoneal shunt. Intraoperative course was complicated by hypertensive urgency, which was effectively managed with high doses of esmolol (500 μg/kg/min). Difficult airway was anticipated due to presence of webbed neck and facial dysmorphism. Tracheal intubation was however successfully accomplished with ...
Hemlata Department of Anaesthesiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, - - 2014
Takayasu's arteritis (TA) is a rare, chronic progressive panendarteritis involving the aorta and its main branches. Anaesthesia for patients with TA is complicated by their severe uncontrolled hypertension, end-organ dysfunction, stenosis of major blood vessels, and difficulties encountered in monitoring arterial blood pressure. In a patient with Cushing's syndrome (CS), ...
Brunori Evelise Helena Fadini Reis EH Escola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, SP, - - 2014
to identify the relationship between different presentations of acute coronary syndrome and cardiovascular risk factors among hospitalized individuals. cross-sectional study performed in a teaching hospital in São Paulo, in the State of São Paulo (SP). Socio-demographic, clinical and anthropometric data of 150 individuals hospitalized due to acute coronary syndrome were ...
Shetty Mallikarjun M Assistant Professor, Department of Medicine, Nizam's Institute of Medical Sciences , Hyderabad, Telangana, India - - 2014
A male aged 45-years presented with complaints of fever for 7days, cough, breathlessness for 4 days, tingling of hands, feet and weakness of both hands and feet for 4 days duration. He was a known asthmatic with history of recurrent sinusitis in the past. On examination he had bilateral polyphonic ...
Valles Jennie M JM Department of Neurology, New York Medical College, Valhalla, N.Y., - - 2014
In 1904, Giuseppe Gradenigo published his case series on the triad of ipsilateral abducens nerve palsy, facial pain in the trigeminal nerve distribution, and suppurative otitis media, which would subsequently be referred to as Gradenigo syndrome. Our patient was a 36-year-old female, 23 weeks pregnant, with a 6-day history of ...
Malik Noureen - - 2014
Budd Chiari syndrome (BCS) is a heterogeneous group of disorders characterized by hepatic venous outflow obstruction at any level from the small hepatic veins to the atrio cava junction. BCS could have serious consequences if not treated promptly. Comprehensive angiographic studies, computerised tomography, liver ultrasonography, histology and pathologic analyses are ...
Kaartinen Kati K School of Medicine, University of Tampere, Savonlinna, - - 2014
Metabolic syndrome (MetS) may have an independent impact on the development of chronic kidney disease. This study examines the prevalence of MetS in subjects with IgA glomerulonephritis (IgAGN) and its impact on disease progression in a retrospective fashion. Altogether, 174 subjects (104 males) were examined 11 years (first visit) after ...
Avdalovic Mark M Division of Pulmonary, Critical Care, and Sleep Medicine, University of California, Davis, School of Medicine, Davis, CA, USA, - - 2014
One of the important factors and consequences in persistent asthma is the change in the vasculature of the airways and lung parenchyma. These changes could contribute to worsening asthma control and predispose asthmatics to critical asthma syndromes. For many years, the contribution of vasculature to severe asthma was limited to ...
Sajan Thomas T Department of Renal Medicine, Goldcoast Hospital Queensland, - - 2014
A 24-year-old man with diarrhea found to have acute renal failure with microangiopathic hemolytic anemia (MAHA). A diagnosis of hemolytic uraemic syndrome (HUS) was made. He was initiated on plasma exchange and hemodialysis. On day 6, he was started on eculizumab. His renal functions progressively improved. His main complication during ...
Satbhai Nilesh G NG Department of Orthopaedic Surgery, Ogori Daiichi General Hospital, Ogori, Yamaguchi, - - 2014
Hopkins syndrome is a rare cause of poliomyelitis-like paralysis affecting 1 or more extremities after an acute attack of asthma. The exact etiology of Hopkins syndrome is not known. A 4-year-old girl developed acute asthma followed by complete flaccid paralysis of the left upper extremity. She underwent staged reconstruction using ...
Garmendia Jenny V - - 2014
Metabolic syndrome (MetS) is a syndrome that involves at least three disorders dyslipidemia, insulin resistance, obesity and/or hypertension. MetS has been associated with several chronic diseases in the adulthood; however, in the recent years, the syndrome was redefined in children. Girls with early menarche and asthma, and children with MetS ...
Ohara Nobumasa N Department of Hematology, Endocrinology and Metabolism, Faculty of Medicine, Niigata University, Niigata, - - 2014
Endogenous Cushing's syndrome is an endocrine disease resulting from chronic exposure to excessive glucocorticoids produced in the adrenal cortex. Although the ultimate outcome remains uncertain, functional and morphological brain changes are not uncommon in patients with this syndrome, and generally persist even after resolution of hypercortisolemia. We present an adolescent ...
Salmi Narimane N Department of Medical Oncology, National Institute of Oncology, Rabat 10000, Morocco ; Université Mohammed V-Souissi, Rabat 8007, - - 2014
We are reporting a case of multifocal reversible leucoencephalopathy syndrome induced by chemotherapy based on Folfox-Bevacizumab regimen. A 44-year-old female, with no history of hypertension, received a chemotherapy based on Folfox-Bevacizumab for her metastatic colon cancer (5 FU: 325 mg/m(2) d1 by intravenous infusion, Oxaliplatin 80 mg/m(2) d1, and Bevacizumab: 7.5 mg/Kg d1). During the fourth cure, ...
Niimi Akio A Division of Respiratory Medicine, Department of Medical Oncology and Immunology, University Graduate School of Medical Sciences, Nagoya City University Hospital, Nagoya, - - 2013
Multiple prospective studies have demonstrated that asthma is among the most common etiologies of chronic cough, along with upper-airway cough syndrome (formerly known as postnasal drip syndrome) and gastroesophageal reflux disease. More recently, the entity of nonasthmatic eosinophilic bronchitis has been appreciated as a significant cause of chronic cough worldwide. ...
Schivo Michael - - 2013
Critical asthma syndrome represents the most severe subset of asthma exacerbations, and the critical asthma syndrome is an umbrella term for life-threatening asthma, status asthmaticus, and near-fatal asthma. According to the 2007 National Asthma Education and Prevention Program guidelines, a life-threatening asthma exacerbation is marked by an inability to speak, ...
Albertson T E - - 2013
The critical asthma syndrome (CAS) encompasses the most severe, persistent, refractory asthma patients for the clinician to manage. Personalized pharmacotherapy is necessary to prevent the next acute severe asthma exacerbation, not just the control of symptoms. The 2007 National Asthma Education and Prevention Program Expert Panel 3 provides guidelines for ...
Ogunlesi Folasade - - 2013
Acute chest syndrome(ACS) is the most common pulmonary complication of sickle cell disease (SCD), the second most common cause of hospitalization and the primary cause of death in patients with sickle cell disease. Its highest prevalence is in early childhood. The pathogenesis of ACS is unknown but many predisposing conditions ...
Albahri Ziad - - 2013
Churg-Strauss syndrome is a rare form of small-vessel vasculitis. In the current report, we describe the case of a 17-year-old Czech girl predominantly characterized by peripheral neuropathy, the presence of cardiac and pulmonary involvement, hypereosinophilia, asthma, and sinusitis that led to the diagnosis of Churg-Strauss syndrome.
Elliot A J - - 2013
This study illustrates the potential of using emergency department attendance data, routinely accessed as part of a national syndromic surveillance system, to monitor the impact of thunderstorm-related asthma. The Emergency Department Syndromic Surveillance System (EDSSS) routinely monitors anonymised attendance data on a daily basis across a sentinel network of 35 ...
Brumpton Ben Michael - - 2013
Obesity is a risk factor for incident asthma in adults, and obesity is a major component of metabolic syndrome. This study aimed to explore the associations of metabolic syndrome and its components with the cumulative incidence of asthma in adults.We conducted a prospective cohort study of participants who were asthma-free ...
Dinić Miroslav Z - - 2013
Churg-Strauss syndrome (CSS) is an allergic granulomatous angiitis, a rare disease of small and medium arteries and veins, associated with the presence of perinuclear antineutrophil cytoplasmic antibodies (p-ANCA). According to the American College of Rheumatology (ACR), there are four or more criteria out of six for the diagnosis: asthma, eosinophilia ...
Blondin Marie-Christine - - 2013
Objective: To present two cases of iatrogenic Cushing's syndrome caused by the interaction of budesonide, an inhaled glucocorticoid, with Ritonavir and itraconazole.Methods: Ae present the clinical and biochemical data of two patients in whom diagnosis of Cushing's syndrome was caused by this interaction. We also reviewed the pertinent literature and ...
Aydin Murat - - 2013
The increasing prevalence of both asthma and obesity are major health problems. Recent studies established a possible link between obesity and asthma; however, the underlying mechanism is not clear. The aim of the study was to analyze the prevalence of metabolic syndrome in postmenopausal subjects with asthma and search the ...
Bhardwaj M - - 2013
Carpenter syndrome is an extremely rare congenital disorder characterized by craniofacial malformations, syndactyly, cardiac defects and obesity. Even after surgical correction of cardiac abnormalities, intrapartum care of a parturient with this condition can be challenging because of progression of residual cardiac defects compounded by the haemodynamic changes of pregnancy. We ...
Morice Alyn H - - 2013
Chronic cough has been suggested to be due to three conditions, asthma, post nasal drip, and reflux disease. A different paradigm has evolved in which cough is viewed as the primary condition characterised by afferent neuronal hypersensitivity and different aspects of this syndrome are manifest in the different phenotypes of ...
Krysiak R R Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland. - - 2013
Endogenous overproduction of glucocorticoids may mask the clinical course of some inflammatory/ autoimmune disorders. In the present paper, we report a man with a history of asthma, which spontaneously remitted after 20 years of duration. Several years later, he was diagnosed with Cushing's syndrome of pituitary origin and underwent transsphenoidal ...
Prajapati Jayesh S - - 2013
Kounis syndrome is defined as the coexistence of acute coronary syndromes with situations associated with allergy or hypersensitivity, as well as anaphylactic or anaphylactoid reactions, to a variety of medical conditions, environmental and medication exposures. We report a case of Kounis-Zavras syndrome type I variant in the setting of aspirin-induced asthma, or ...
Lote Hazel - - 2013
48, XXYY syndrome is a form of sex chromosome aneuploidy that affects between 1 in 18 000 to 1 in 40 000 males. It is not inherited and is diagnosed by karyotyping. It has similarities to 47, XXY Klinefelter's syndrome, with tall stature, micro-orchidism, hypergonadotropic hypogonadism and infertility in males. However, patients ...
Manu G K - - 2013
The Churg-strauss syndrome (CSS), also referred to as allergic angiitis and granulomatosis is characterized by asthma, peripheral and tissue eosinophilia, extravascular granuloma formation, and vasculitis of multiple organ systems. It is an uncommon disease with an estimated annual incidence of 1-3 per million. Here, we report a case of CSS ...
Stolte M - - 2013
The Churg-Strauss syndrome (CSS), first described in 1951 and characterised by eosinophilic inflammation and necrotising vasculitis in patients with asthma can in principle affect any organ. We report on a 47-year-old male patient, in whom the diagnosis of CSS was finally established for the first time on the basis of ...
Akiyama Takuya - - 2013
We report the case of a 57-year-old woman, known to have had allergic sinusitis and bronchial asthma, and had been treated with leukotriene receptor antagonist for one month, at the time of presentation. She complained of bilateral weakness and pain in her lower extremities and her laboratory investigations revealed an ...
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