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Li Hanhan H Hanhan Li, Dane E Klett, Raymond Littleton, Jack S Elder, Jesse D Sammon, VUI Center for Outcomes Research Analytics and Evaluation, Henry Ford Health System, Detroit, MI 48202, United - - 2014
Metabolic syndrome has been implicated in the pathogenesis of uric acid stones. Although not completely understood, its role is supported by many studies demonstrating increased prevalence of uric acid stones in patients with metabolic syndrome and in particular insulin resistance, a major component of metabolic syndrome. This review presents epidemiologic ...
Hu Hui H Department of Epidemiology, College of Public Health and Health Professional and College of Medicine, University of Florida, Gainesville, FL 32610, United - - 2014
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental toxic compounds formed from incomplete combustion of carbon-containing materials, cigarette smoking, and food cooking. The genotoxic effects of PAHs have been widely studied. However, their nongenotoxic effects such as their impacts on glucose and metabolic homeostasis have not been well examined. We used ...
Bengston S E SE Department of Ecology and Evolutionary Biology, University of Arizona, PO Box 210088, Tucson, AZ 85721-0088, USA - - 2014
Consistent individual variation in animal behaviour is nearly ubiquitous and has important ecological and evolutionary implications. Additionally, suites of behavioural traits are often correlated, forming behavioural syndromes in both humans and other species. Such syndromes are often described by testing for variation in traits across commonly described dimensions (e.g. aggression ...
Seeber Beata - - 2014
High plasma concentrations of the vitamin E-binding protein afamin have been previously shown to be associated with insulin resistance and metabolic syndrome. We set out to determine whether the concentration of afamin in the serum of women with polycystic ovarian syndrome (PCOS) is elevated in relation to the presence and ...
Ambiel Marcela Vendruscolo MV Universidade de São Paulo, Ribeirão Preto, SP, - - 2014
Pemphigus foliaceus and pemphigus vulgaris are endemic in the northeastern region of São Paulo State, Brazil. They are treated mainly with systemic corticosteroids, which may provoke osteoporosis; atherosclerosis, higher blood pressure, insulin resistance, glucose intolerance, hyperlipidemia and abdominal obesity. These side effects of corticoids also constitute criteria for the diagnosis ...
Kronenberg Florian F Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, - - 2014
-Afamin is a human plasma vitamin E-binding glycoprotein primarily expressed in the liver and secreted into the bloodstream. Since little is known about (patho)-physiological functions of afamin, we decided to identify phenotypes associated with afamin by investigating transgenic mice overexpressing the human afamin gene and performing large-scale human epidemiological studies. ...
Adams-Huet Beverley B 1 Department of Clinical Sciences, University of Texas Southwestern Medical Center , Dallas, - - 2014
Abstract Background: Although hepatic insulin resistance has been documented in patients with metabolic syndrome using homeostasis model assessment of insulin resistance (HOMA-IR) as a measure, there is scanty data on adipose insulin resistance (Adipo-IR) and its relationship with the dysregulation of adipokines in metabolic syndrome. Thus, we examined whether Adipo-IR ...
Jialal Ishwarlal I Laboratory for Atherosclerosis and Metabolic Research, Department of Pathology, Division of Endocrinology, Diabetes and Metabolism, University of California Davis Medical Center , and VA Medical Center, Sacramento, - - 2014
Abstract Endotoxemia, which is now emerging as a feature of metabolic syndrome, is believed to contribute to the chronic low-grade inflammatory status and insulin resistance of the syndrome. Lipopolysaccharides (LPS), or endotoxins, bind to LPS-binding protein and activate pattern recognition receptors, classically Toll-like receptor-4, mediating inflammation. Increased gut permeability and ...
Drouet Michel M *Institut de Recherche Biomédicale des Armées, Department of Radiobiology, BP73, 91223, Brétigny sur Orge, - - 2014
Acute radiation syndrome represents the clinical response of radiation-sensitive key tissues (i.e., hematopoietic, gastrointestinal and neurovascular) following exposure to high doses of ionizing radiation. In this context, the hematopoietic syndrome remains the first therapeutic challenge. Today, identifying new drugs and developing new strategies to cope with acute radiation syndrome remain ...
Canbulat Nejla N Department of Pediatric Nursing, School of Health, Karamanoglu Mehmetbey University, Karaman, - - 2014
The aim of this study was to explore a deeper insight into experiences of Turkish mothers living with/diagnosed with Down syndrome (DS) baby. Individual and audiotaped interviews were carried out with 11 women after amniocentesis in Karaman city of Turkey between August 2012 and February 2013. Transcribed semistructured interviews were ...
Kwon Jung Hye JH Division of Hemato-oncology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of - - 2014
Objective: The purpose of this case series was to describe patients with aberrant drug-related behaviors and similar patterns of dose escalation in whom interdisciplinary assessment revealed different bases for their dose increases. Method: During the period from December 26 to December 30, 2011, the medical records of two patients with ...
Herman Andrea - - 2014
Sjögren's syndrome is a chronic systemic autoimmune disease that can affect any organ system in the body. The most common symptoms are dryness of the mouth and eyes resulting from chronic inflammation and a progressive loss of secretory function. As with most individuals managing a chronic condition, patients with Sjögren's ...
Van Herwegen Jo J Department of Psychology, Kingston University, UK. Electronic address: - - 2014
Although individuals with Williams syndrome are very sociable, they tend to have limited contact and friendships with peers. In typically developing children the use of positive emotions (e.g., happy) has been argued to be related to peer relationships and popularity. The current study investigated the use and development of emotion ...
Morbey Roger A RA Public Health England, - - 2014
Prior to the 2012 London Olympic and Paralympic Games, new statistical methods had to be developed for the enhanced syndromic surveillance during the Games. Different methods were developed depending on whether or not historical data were available. Practical solutions were needed to cope with the required daily reporting and data ...
Kursawe Romy - - 2014
The ever growing prevalence of childhood obesity is being accompanied by an increase in the pediatric population of diseases once believed to be exclusive of the adulthood such as the metabolic syndrome (MS). The MS has been defined as the link between insulin resistance, hypertension, dyslipidemia, impaired glucose tolerance, and ...
Sørensen Anja Elaine AE Department of Science, Systems and Models, Roskilde University, Universitetsvej 1, Roskilde 4000, Denmark. - - 2014
Polycystic ovary syndrome (PCOS) is the most common, though heterogeneous, endocrine aberration in women of reproductive age, with high prevalence and socioeconomic costs. The syndrome is characterized by polycystic ovaries, chronic anovulation and hyperandrogenism, as well as being associated with infertility, insulin resistance, chronic low-grade inflammation and an increased life ...
Lerchbaum Elisabeth E Department of Internal Medicine, Division of Endocrinology and Metabolism, Medical University of Graz, Graz, Austria; University Women's Hospital, Heidelberg, - - 2014
To evaluate the association between androstenedione, testosterone, and free testosterone and metabolic disturbances in polycystic ovary syndrome. We analyzed the association between androstenedione, testosterone, and free testosterone and metabolic parameters in a cross-sectional study including 706 polycystic ovary syndrome and 140 BMI-matched healthy women. Polycystic ovary syndrome women were categorized ...
Cortez Melissa M Imaging and Neurosciences Center, University of Utah, Salt Lake City, UT, - - 2014
There is increasing evidence that impaired glucose tolerance (IGT) or metabolic syndrome may result in peripheral nerve injury, although the exact relationship between the conditions is still being characterized. There is animal model, epidemiologic, and clinical evidence to suggest a pathophysiologic relationship between neuropathy and metabolic syndrome, along with its ...
Oh Hye Jin - - 2011
We report a case of a 51-year-old woman with Evans syndrome (autoimmune hemolytic anemia and primary immune thrombocytopenia) and hypothyroidism. She was previously diagnosed with Hashimoto's thyroiditis in 1994 (age, 35) and autoimmune hemolytic anemia (AIHA) 3 years ago. She was treated with oral prednisolone. After a period, in which ...
Yin Zhiqiang - - 2011
A 16-year-old girl with polycystic ovarian syndrome presented with numerous rufous papules arising within a large depigmented macule that developed following a severe scald injury on the back. Histopathology revealed that many mature sebaceous glands were growing in the middle and bottom of the epidermis with slight acanthosis. On the ...
Sun Z - - 2011
Objectives:We report two cases of congenital salivary fistula of an accessory parotid gland, and we discuss its occurrence in Goldenhar syndrome.Methods:Two teenagers complained of a congenital cheek fistula with constant salivary discharge. Computed tomography fistulography and sialography were performed. The diagnosis of Goldenhar syndrome was established based on clinical and ...
Greenwell-Wild Teresa - - 2011
Sjögren's syndrome (SS) is a chronic autoimmune disease of unknown etiology that targets salivary and lacrimal glands and may be accompanied by multiorgan systemic manifestations. To further the understanding of immunopathology associated with SS and identify potential therapeutic targets, we undertook the present study comparing the gene expression profiles of ...
Wang Xian-Ling - - 2011
A rare case with ectopic adrenocorticotrophic hormone syndrome (EAS) caused by medullar thyroid carcinoma (MTC) in mediastinum was reported. This 49 year-old male patient initially presented with serious and intractable hypokalemia. Endocrine evaluations showed adrenocorticotrophic hormone (ACTH)and urinary free cortisols were at higher levels, and could not be suppressed by ...
Marom Tal - - 2011
The allelic loss of 22q11.2 results in various developmental failures of pharyngeal pouch derivatives ("22q11.2 deletion syndromes", 22q.11DS), consequently affecting the anatomy and physiology of head and neck (H&N) organs. The objective of this paper was to describe those manifestations. Two 22q11.2DS patients with H&N manifestations were studied along with ...
Yasuda Keiko - - 2011
A 69-year-old Japanese woman without any specific medical or family history was admitted to our hospital for renal insufficiency with proteinuria. On laboratory examinations, deteriorated renal function (blood urea nitrogen level was 34.9 mg/dL and creatinine level was 1.78 mg/dL) and elevated urinary levels of N-acetyl-β-D: -glucosaminidase (23.4 U/L) and β2-microgloblin (20200 μg/L) were ...
Krysiak R R Department of Internal Medicine and Clinical Pharmacology, Medical University of Silesia, Katowice, Poland. - - 2011
Empty sella syndrome is a consequence of the herniation of the subarachnoid space within the sella associated with flattering of the pituitary gland. In this paper, we describe the atypical clinical manifestation of this condition in a 27-year-old survivor of thyroid cancer. We associate the development of empty sella syndrome ...
Jin Wu - - 2011
BACKGROUND: Concurrent deficiencies of three hormones in patients with Turner's syndrome (TS) have rarely been reported. Here, we describe a case of a young girl who had Turner's syndrome with concomitant chronic lymphocytic thyroiditis, growth hormone deficiency, and hypothyroidism with cardiopericarditis. CASE: An 11-year-old girl was referred to the outpatient ...
Sawant Sangita U - - 2011
Background. The present study is to look for a correlation between oxidative stress and thyroid function in patients with the nephrotic syndrome in the remission phase as well as in a persistent proteinuric state. Introduction. Nephrotic syndrome is a form of chronic kidney disease due to which blood loses protein ...
Takasu Nobuyuki - - 2011
A 36-year-old woman with postpartum hypopituitarism (Sheehan's syndrome: SS) developed postpartum autoimmune thyroiditis (PPAT). She delivered a baby by Caesarean section (620 mL blood loss). At 1 month post partum, she developed thyrotoxicosis due to painless thyroiditis (autoimmune destructive thyroiditis). She was positive for antithyroid antibodies. Postpartum and hypoadrenalism-induced exacerbation of ...
Bizhanova Aigerim - - 2011
Pendred syndrome is an autosomal recessive disorder defined by sensorineural deafness, goiter and a partial organification defect of iodide. It is caused by biallelic mutations in the multifunctional anion transporter pendrin/SLC26A4. In human thyroid tissue, pendrin is localized at the apical membrane of thyroid follicular cells. The clinical phenotype of ...
Rubbia-Brandt Laura - - 2010
Sinusoidal obstruction syndrome (SOS), formerly named venoocclusive disease, is a well-known complication of hematopoietic stem cell transplantation and ingestion of food or drinks contaminated by pyrrolizidine alkaloids. Many other drugs and toxins have been associated with SOS, including several chemotherapeutic agents and immunosuppressors. SOS contributes to significant morbidity and mortality ...
Vivanco-Allende A - - 2011
We present the case of a 4-month-old girl with PHACES syndrome and severe upper respiratory airway obstruction secondary to multiple subglottic and tracheal hemangiomas effectively treated with heliox-CPAP delivered by helmet (HH-CPAP). Pediatr Pulmonol. 2011; 46:306-308. © 2011 Wiley-Liss, Inc.
Sturiale Carmelo Lucio - - 2011
Midbrain multiloculated cystic formations can rarely origin by enlargement of Virchow-Robin spaces surrounding mesencephalo-thalamic artery and branches of the collicular and accessory collicular arteries. They can determine several pictures of midbrain syndrome and obstructive hydrocephalus. The authors describe a 38 year-old man affected by a Benedikt's syndrome related to a ...
Courtier Jesse - - 2010
We reviewed the sonographic and MRI findings of tracheolaryngeal obstruction in the fetus. Conditions that can cause tracheolaryngeal obstruction include extrinsic causes such as lymphatic malformation, cervical teratoma and vascular rings and intrinsic causes such as congenital high airway obstruction syndrome (CHAOS). Accurate distinction of these conditions by sonography or ...
Roybal Jessica L - - 2010
Congenital high airway obstruction syndrome (CHAOS) is caused by complete or near-complete obstruction of the fetal airway. Obstruction sets in motion a sequence of events that can ultimately lead to fetal demise. However, on rare occasions in utero airway decompression occurs, reversing syndromic findings and improving the prognosis. In our ...
Lee Jih-Teng - - 2010
Haddad syndrome is characterized by congenital central hypoventilation syndrome (Ondine's curse) associated with segmental distal gut aganglionosis (Hirschsprung's disease). The prognosis of Haddad syndrome is very poor, and survival is often less than 2 years. Treatment of Hirschsprung's disease is usually influenced by the association with Ondine's curse. We report ...
Day Andrew - - 2010
Lipomas are benign, encapsulated, soft-tissue tumours composed of well-differentiated adipocytes. They arise in the subcutaneous tissue typically on the back, shoulder and neck. Lipomas have been known to cause symptomatic obstruction to venous flow by compression. We report a case of venous obstruction syndrome due to a small lipoma within ...
Zheng Hongbo - - 2010
The authors describe a patient with pseudotumor cerebri syndrome who showed at venography a giant arachnoid granulation in the left dominant transverse sinus and hypoplasia of the contralateral transverse sinus with high pressure proximal to the obstruction. Dilation of the left transverse sinuses with a stent reduced both the pressure ...
Rao Yashwant K - - 2010
An 18-month-old boy was admitted with fever, abdominal pain, and hepatomegaly. CT scan revealed dilatation of intrahepatic biliary radicals with central dot sign, bilateral nephrocalcinosis, multiple ureteric and urinary bladder stones and right-sided obstructive hydroureteronephrosis due to a ureterovesical calculus of about 1.5 cm. Liver biopsy showed early hepatic fibrosis.
Ramirez Ruben - - 2010
Acute colonic pseudo-obstruction is characterized by symptoms, signs and radiologic appearance of large bowel obstruction in the absence of a true mechanical obstruction. Several pharmacologic treatments have been proposed. We present a case of a patient with Guillain-Barr? syndrome complicated by acute colonic pseudo-obstruction, who had a clinical response to ...
Wong Derek T H - - 2010
Scimitar syndrome is a rare cause of left-to-right shunting. Surgery is indicated for a pulmonary-to-systemic blood flow ratio greater than 1.5:1 and not infrequently is complicated by postoperative obstruction. This report presents a case of scimitar syndrome and reviews how magnetic resonance imaging (MRI) can be used for initial and ...
Han Sang Won - - 2010
While tonic pupils have been attributed to various diseases, including syphilis, herpes zoster, orbital trauma, temporal arteritis, endometriosis, and paraneoplastic syndromes, obstructive hydrocephalus has not been implicated. A 36-year-old woman visited a neurology department with a 7-day history of throbbing headache and blurred vision in both eyes. She had early ...
So Chi-Yung - - 2010
Cerebro-costo-mandibular syndrome (CCMS) consists of severe micrognathia, glossoptosis, posterior rib-gap defects and developmental delay. It may cause upper airway obstruction andflail chest, resulting in neonatal hypoxia, and possibly death. Early airway management or surgical intervention to maintain a patent airway is critical to avoid hypoxia in CCMS patients. We report ...
Migliore Federico - - 2010
Takotsubo syndrome, also called apical ballooning syndrome, is a clinical entity characterized by transient hypokinesis, akinesis, or dyskinesis of the left ventricular mid-segments with or without apical involvement, and without obstructive coronary lesions. The contemporary presence of left ventricular outflow tract obstruction (LVOTO), systolic anterior motion of the anterior mitral ...
Bannink N - - 2010
Almost 50% of patients with Apert, Crouzon or Pfeiffer syndrome develop obstructive sleep apnea (OSA), mainly due to midface hypoplasia. Midface advancement is often the treatment of choice, but the few papers on long-term outcome report mixed results. This paper aimed to assess the long-term respiratory outcome of midface advancement ...
Sasaki Takamitsu - - 2010
Limy bile syndrome is a rare condition in which the gallbladder is filled with a paste-like radiopaque material. The presence of limy bile in the common bile duct is rare. A 72-year-old woman was admitted to our hospital with epigastric pain and jaundice. Plain abdominal radiography on admission showed a ...
Ashrani Aneel A AA Division of Hematology, Department of Internal Medicine, College of Medicine, Mayo Clinic, Rochester, MN 55905, USA. - - 2009
Venous stasis syndrome may complicate deep vein thrombosis (DVT; i.e. post-phlebitic syndrome), but, in most cases, venous stasis syndrome is not post-phlebitic. The objective of this study was to determine the risk factors (including prior DVT) for venous stasis syndrome, and to assess venous outflow obstruction and venous valvular incompetence ...
Erlandson Michael D - - 2009
Bouveret syndrome is a rare complication of cholelithiasis occurring when a gallstone passes through a cholecystoduodenal or choledochoduodenal fistula and lodges in the pylorus or proximal duodenum causing a gastric outlet obstruction. The case of a 70-year-old male who developed Bouveret syndrome is presented, and the management of this presentation ...
Gibson P G - - 2009
There is a need to re-evaluate the concept of asthma and chronic obstructive pulmonary disease (COPD) as separate conditions, and to consider situations when they may coexist, or when one condition may evolve into the other. Epidemiological studies show that in older people with obstructive airway disease, as many as ...
Schiffer Eduardo - - 2009
BACKGROUND AND OBJECTIVES: Oxaliplatin is a chemotherapeutic drug for colorectal adenocarcinoma able to extend the indications for resection of colorectal liver metastases. However, the drug may severely injure hepatic sinusoids, inducing a sinusoidal obstruction syndrome in non-tumoral parenchyma with a risk of decreased regeneration in the remnant liver following partial ...
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