In total, 41 consecutive patients with "idiopathic carpal tunnel syndrome" and abnormal electrophysiologic findings who underwent carpal tunnel release were studied prospectively. The focus of this investigation was the evaluation of the levels of specific chemical mediators within the serum and flexor tenosynovium of these patients. Blood was collected from ...

Spontaneous rupture of esophagus (Boerhaave syndrome) is a life-threatening emergency requiring immediate surgical management. The diagnosis is often delayed and results in high mortality and morbidity. Typical clinical presentations are postprandial vomiting and subsequent chest or back pain, which alert the clinicians to take chest film and esophagogram for diagnosis. ...

Transurethral resection of the prostate (TURP) has been the standard treatment for moderate to severe benign prostatic hypertrophy since the 1930s. Transurethral resection (TUR) syndrome, one complication that can occur during a TURP procedure, is water intoxication of the body that results in hyponatremia and other acid-base imbalances. This complication ...

This study tested for evidence supporting the clinical lore of three sequential stages of complex regional pain syndrome (CRPS) and examined the characteristics of possible CRPS subtypes. A series of 113 patients meeting IASP criteria for CRPS underwent standardized history and physical examinations to assess CRPS signs and symptoms in ...

We present two cases of acute carpal tunnel syndrome in patients with haemophilia A. There have been only a few cases reported and controversy exists as to whether conservative or surgical treatment should be given in the acute phase. We successfully decompressed the carpal tunnel in both cases. The numbers ...

PURPOSE: Ideally, decompression of the coracoacromial arch in patients with shoulder impingement syndrome should be done only at the site of impingement. However, it is very difficult to determine the exact site of impingement before acromioplasty. The objectives of this study were to investigate the relationship between findings and the ...

Although the red nucleus often has been suggested to be the lesion site responsible for Claude's syndrome, the precise localization of the syndrome is uncertain. Lesion sites were reviewed in six patients with Claude's syndrome and compared with other patients with the syndrome identified by a literature search. The findings ...

BACKGROUND: Carpal tunnel syndrome is a common disorder, which can be treated with surgery or conservative options. However, there is insufficient evidence and no consensus among physicians with regard to the preferred treatment for carpal tunnel syndrome. Therefore, a randomized controlled trial is conducted to compare the short- and long-term ...

We treated three patients for carpal tunnel syndrome which developed more than 10 years after reconstructive surgery for radial dysplasia. All responded to decompressive surgery. The radial carpal bones were hypoplastic in all cases, and in two we measured the carpal tunnel with computed tomography (CT). This showed that the ...

OBJECTIVE: We investigated the frequency and inter-relationship of neuropsychiatric disturbances in a population sample of persons suffering from Alzheimer's disease (AD). METHOD: Screening 5,092 elderly residents (90% of the population aged 65 and older) of Cache County, Utah, for dementia, we identified 198 persons with AD using a comprehensive neuropsychiatric ...

The slipping rib syndrome is an infrequent cause of thoracic and upper abdominal pain and is thought to arise from the inadequacy or rupture of the interchondral fibrous attachments of the anterior ribs. This disruption allows the costal cartilage tips to sublux, impinging on the intercostal nerves. Children with this ...

The flexor digitorum accessorius longus is a rare muscular anomaly that has been reported as one of the etiologies of tarsal tunnel syndrome. The authors provide a case report of a patient with tarsal tunnel syndrome that resolved with resection of the flexor digitorum accessorius longus. The patient remains asymptomatic ...

Cheilitis granulomatosa is the most frequent dermatological sign in the Melkersson-Rosenthal syndrome. We reviewed 27 cases of this syndrome diagnosed and treated in the last 20 years. All the patients were surgically treated and received intralesional corticosteroids during surgery and tetracycline hydrochloride (500 mg, twice daily) after the operation to ...

We describe a girl of Turkish descent suffering from a peculiar combination of symptoms. The presenting complaint was bilateral lymphedema of the legs; additional symptoms include hypotrichosis, telangiectasias and angiomata limited to acral regions. We discuss the possibility that this girl suffers from Noonan/cardio-facio-cutaneous syndrome. We conclude that the combination ...

Mixed connective tissue disease is a rheumatological syndrome with neuromuscular manifestations that may include inflammatory myopathy and carpal tunnel syndrome. We report a patient who presented with an inflammatory myopathy and bilateral carpal tunnel syndrome prior to the diagnosis of a connective tissue disorder. Early in the course of treatment, ...

The aim of this study was to determine and evaluate nerve compression syndromes of the upper and lower extremity in sport climbing. Although considerable research has been conducted on orthopedic problems associated with sport climbing, there has been little comprehensive evaluation of the associated neurological problems. The retrospective study performed ...

Knee injuries affect millions of Americans each year. Acute injuries, which commonly occur among athletes or in occupational accidents, include injuries to the ligaments and menisci. Overuse syndromes include patellofemoral pain syndrome, tendonitis, bursitis, and iliotibial band friction syndrome and occur as a result of repetitive soft-tissue trauma. Whether knee ...

Sanfillippo B syndrome (mucopolysaccharidosis (MPS) III, type B) is characterized by mild expression of the characteristic 'Hurler' phenotype and a severe central nervous system involvement. We report three patients with Sanfilippo B syndrome, referred to our clinic because of peculiar facies, delay in language development and behavioral problems, at the ...

BACKGROUND: Carpal tunnel syndrome is a debilitating neuropathy affecting millions of individuals. Although there are published reports of familial associations of carpal tunnel syndrome, the molecular mechanisms are unknown. OBJECTIVE: To determine the prevalence and potential role of the chromosome 17 microdeletion associated with hereditary neuropathy with liability to pressure ...

Exposure to vibrating hand-held tools can cause a variety of vascular and neuromuscular symptoms collectively named Hand-Arm Vibration Syndrome (HAVS). The clinical presentation of this syndrome includes paraesthesiae or tingling in digits, pain or tenderness in the wrist and hand, digital blanching, cold intolerance, weakness of the finger flexors or ...

Diagnosis of proximal median nerve compression (PMNC) remains a clinical challenge. The authors hypothesized that measurement of the sensibility of the thenar eminence might identify PMNC by demonstrating abnormal function in the palmar cutaneous branch of the median nerve. This hypothesis was evaluated by means of quantitative sensory testing of ...

Different clinical entities are associated with elongation of the styloid process or ossification of the stylohyoid ligament. Although partial ossification of the stylohyoid ligament is not uncommon, complete ossification is rare. We present a rare case of complete ossification of the stylohyoid ligament. This case may represent the extreme end ...

PURPOSE: While bladder dysfunction, particularly detrusor-sphincter incoordination, appears to be associated with a higher ureteral reimplantation failure rate, the potential effect of the urge syndrome or detrusor instability alone on surgical outcome remains unclear. We assessed the effect of the underlying urge syndrome on the outcome of ureteral implantation in ...

Two cases of carpal tunnel syndrome with Riche-Cannieu anomalies are reported. Despite complete absence of a median nerve evoked compound muscle action potential from the thenar eminence, these patients had significant preservation of function and minimal muscle atrophy. Activation of the ulnar nerve at both the wrist and elbow generated ...

Meralgia paresthetica is an entrapment syndrome of the lateral cutaneous nerve of the thigh manifesting as paresthesia, pain, numbness, or sensory loss in the distribution of the nerve. A variety of causes have been described; however, the etiology often remains unknown. On the basis of our investigations with a patient ...

BACKGROUND: Muenke's syndrome is a rarely seen craniosynostosis syndrome. Bilateral or unilateral coronal craniosynostosis, brachydactyly, tarsal and carpal coalitions are the typical clinical findings. Sensorineural hearing loss is reported in more than 30% of the affected patients. In patients with Muenke's syndrome intracranial vascular dysplasia has not been reported yet. ...

OBJECTIVES: To evaluate serial central motor conduction time in the Miller Fisher syndrome. METHOD: Three patients with classic Miller Fisher syndrome were evaluated clinically. They had serial central motor conduction times measured with transcranial magnetic stimulation and nerve conduction studies. Motor evoked potentials were recorded from the first dorsal interossei ...

Os trigonum syndrome refers to a constellation of findings that can result in significant posterior or lateral ankle pain. The diagnosis may be very challenging for the clinician; nonetheless, modern imaging techniques can reliably aid in the diagnosis and in determining the extent of injury. This article explores the anatomy, ...

A case of an anomalous interconnection between the tendons of the flexor pollicis longus and the flexor digitorum profundi to both the index and middle fingers at the wrist of a patient presenting with carpal tunnel syndrome is described. The contents of the carpal tunnel should be inspected carefully at ...

The strict definition of the Ramsay Hunt syndrome is peripheral facial nerve palsy accompanied by an erythematous vesicular rash on the ear (zoster oticus) or in the mouth. J Ramsay Hunt, who described various clinical presentations of facial paralysis and rash, also recognised other frequent symptoms and signs such as ...

Transcarpal motor conduction to abductor pollicis brevis (APB) was evaluated in 43 patients (70 hands) with suspected carpal tunnel syndrome (CTS). Transcarpal motor conduction was abnormal in 80% of hands compared with 11.5% with prolongated distal motor latency from wrist stimulation. Transcarpal motor conduction was comparable in sensitivity with transcarpal ...

Overuse syndromes in the wrist or hand can occur from repetitive use of the wrist and hand or from recurrent direct trauma to the hand area. Tendinitis syndromes due to overstretching or shear stress are seen commonly on both the extensor and flexor sides of the wrist. Overuse syndromes also ...

Most authors agree that surgical decompression is the treatment of choice for tarsal tunnel syndrome when conservative treatment fails. Overall, the results of surgical treatment for tarsal tunnel have been favorable. Studies have shown that surgical release improves or resolves symptoms of tarsal tunnel syndrome in 85% to 90% of ...

Keloid scarring of the distal upper extremity is very rare. We report a Caucasian woman who presented with aggressive keloids of the hand and wrist causing De Quervain's syndrome, superficial radial-nerve entrapment and ulnar-nerve compression at the wrist. Multiple operations were required to alleviate her symptoms. A number of management ...

Occupations of two geographically distinct populations of patients with upper limb pain were examined. Relative risks for being in an occupation were calculated for subjects with epicondylitis, carpal tunnel syndrome, and pain syndromes in one population and nonspecific occupational overuse syndrome (OOS) in the other. Population A subjects (806 female, ...

A 56-year-old man presented with a mass of the right wrist limiting excursion of the digits. Operative exploration demonstrated gouty infiltration of the flexor tendons. The tendons were debrided of the urate crystalline material and the motion of the digits returned, preserving all tendon function. The patient later returned with ...

Although pronator syndrome is often misdiagnosed and does not occur as frequently as carpal tunnel syndrome, its clinical features are well described, and the diagnosis should be made if the clinical features are understood and reasonable suspicion exists. The differentiating features between carpal tunnel syndrome and pronator syndrome should be ...

A survey was done of employees who were identified as frequent computer users. Although 29.6% of the employees reported hand paresthesias, only 27 employees (10.5%) met clinical criteria for carpal tunnel syndrome, and in 9 (3.5%) the syndrome was confirmed by nerve conduction studies. Affected and unaffected employees had similar ...

Charles Bonnet syndrome (CBS) appears to be commoner in elderly people than was previously thought. Nonetheless, as yet, no firm diagnostic criteria have been established for CBS, leaving the need for well-defined diagnostic criteria describing this syndrome unfulfilled. Two recently proposed diagnostic criteria for CBS insist on an absence of ...

BACKGROUND: Persian Gulf syndrome is a set of symptoms that do not fit into well-understood diagnostic categories. Among these symptoms, there are some that could suggest a generalized neuropathic process. OBJECTIVE: Correlate neurological symptoms with objective electrodiagnostic findings. METHODS: A randomized sample of 176 Persian Gulf veterans (PGV) evaluated at ...

A constricting band causing tourniquet syndrome is a common problem that can cause much frustration and pain for both the patient and practitioner. The following review classifies and describes the different aspects of the treatment of this condition. We also describe a policy and procedure for the motorized removal of ...

PURPOSE: The Susac syndrome is a microangiopathy that leads to visual symptoms, hearing loss and neurological symptoms. CASE REPORT: We report on a young woman suffering from this syndrome who also presented the following signs and symptoms typical of a vasospastic syndrome; 1) a history of cold hands, low blood ...

Piriformis syndrome remains a controversial diagnosis, despite its having first been described over 60 years ago. The controversy stems from several factors: variable and sometimes unclear cause, similarity to other more easily recognizable causes of sciatica, lack of consistent objective diagnostic findings, and relative rarity. Nevertheless, it is reasonable to ...

TOS represents a spectrum of disorders encompassing four related syndromes: arterial compression, venous compression, neurogenic compression, and a poorly defined pain syndrome. Patients can present with signs of arterial insufficiency, venous obstruction, painless wasting of intrinsic hand muscles, and pain. History and physical examination are the most important diagnostic studies, ...

The choice for surgical treatment of cubital tunnel syndrome is no clearer today than when it was reviewed 10 years ago. There continue to be no significant prospective randomized trials to adequately compare the different surgical techniques. Even if such a trial were performed, most hand surgeons would probably continue ...

Hematocolpos should be considered in adolescent girls who present with lower abdominal pain, a pelvic mass, and primary amenorrhea. The authors describe a rare case of a young child with Down's syndrome, precocious puberty, and hematocolpos caused by a transverse vaginal septum. The diagnosis was facilitated using a combination of ...

Ulnar artery aneurysms distal to the carpal ligament represent an uncommon but uniquely characteristic disease entity. As a result of repetitive palmar trauma, the hypothenar hammer syndrome should be suspected in males with this history and unilateral digital ischemia which spares the thumb. The pathophysiology of this syndrome and its ...

Trigeminal trophic syndrome is an uncommon clinical entity in which cutaneous trophic ulceration develops with continuous manipulation of trigeminal dermatomes. Patients spontaneously refer picking, rubbing and/or scratching at the affected areas because of hypo-anaesthesia, paraesthesia and/or pain following damage of the sensory trigeminal fibres or nuclei. We herein describe a ...

Ischemia of the optic nerve may occur in several forms, usually associated with vasculopathic risk factors or vasculitis, and may present with various patterns of optic disc appearance and dysfunction. Though a proven therapy is not available for the most common syndromes, correct identification may present severe visual loss or ...

Guyon's canal syndrome, an ulnar nerve entrapment at the wrist, is a well-recognized entity. The most common causes that involve the ulnar nerve at the wrist are compression from a ganglion, occupational traumatic neuritis, a musculotendinous arch and disease of the ulnar artery. We describe two cases of Guyon's canal ...