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Ossig Christiana C Division of Neurodegenerative Diseases, Department of Neurology, Dresden University of Technology, Fetscherstraße 74, Dresden 01307, Germany; Department of Neurology, Dresden University of Technology, Fetscherstraße 74, Dresden 01307, Germany; Department of Neuropsychiatry and Laboratory of Molecular Psychiatry, Charité-Universitätsmedizin Berlin, Berlin 10117, Germany. Electronic address: - - 2015
The initiation of therapy in Parkinson disease (PD), altering the medication, adding new substances, and switching to alternative therapies throughout the disease is always a matter of debate. In the past, experts in PD have propagated different medication strategies. Even though there is no new medical treatment on the horizon, ...
Agarwala Anandita A Department of Medicine, Baylor College of Medicine, Michael E. DeBakey Veterans Affairs Medical Center, One Baylor Plaza, Houston, TX, 77030, USA, - - 2015
Antisense oligonucleotide therapy is a promising approach for the treatment of a broad variety of medical conditions. It functions at the cellular level by interfering with RNA function, often leading to degradation of specifically targeted abnormal gene products implicated in the disease process. Mipomersen is a novel antisense oligonucleotide directed ...
Saunders Nick N PHE Microbiology Services Colindale, 61 Colindale Avenue, London, NW9 5EQ, - - 2015
This chapter describes the process of validating in-house molecular assays although the principles described are equally relevant to all diagnostic assays. The best practice principles described below are based on the In Vitro Diagnostic Medical Devices Directive (IVDD) and associated documentation. Although compliance with these regulations is not required for ...
Plakiotis Christos C Department of Psychiatry, School of Clinical Sciences at Monash Health, Monash University, Melbourne, VIC, Australia, - - 2015
There is widespread concern in Australia and internationally at the high prevalence of psychotropic medication use in residential aged care facilities. It is difficult for nurses and general practitioners in aged care facilities to cease new residents' psychotropic medications when they often have no information about why residents were started ...
Koven Suzanne S From Massachusetts General Hospital and Harvard Medical School - both in - - 2014
Although the lists of medical complaints that some patients bring to appointments may irritate doctors, they seem to serve a salutary purpose. Perhaps naming our demons aloud makes them less frightening. Or maybe concerns set in ink seem less likely to be ignored.
Trulove William G WG DaVita HealthCare Partners Inc., Kingwood, Texas - - 2014
The nephrologist serving as medical director of a dialysis clinic must understand that the role of director is not simply an extension of being a good nephrologist. The two roles-nephrology practice and the leadership of a dialysis clinic-may be filled by a single person. However, each role contains unique tasks, ...
Apperley Jane F JF Department of Haematology, Imperial College London, London, UK. Electronic address: - - 2014
In less than 10 years, the prognosis of chronic myeloid leukaemia has changed from that of a fatal disease to a disorder amenable simply to lifelong oral medication and compatible with a normal lifespan. This change has been made possible by a deep understanding of the molecular pathogenesis and a ...
Feghhi Daniel P DP Departments of Orthopaedics (D.P.F., D.K., and S.S.) and Neurological Surgery (N.A.), New Jersey Medical School, Rutgers Biomedical and Health Sciences, 90 Bergen Street, Suite 7300, Newark, NJ 07101. E-mail address for S. Sabharwal: - - 2014
Increased availability of medical information on the Internet empowers patients to look up answers to questions about their medical conditions. However, the quality of medical information available on the Internet is highly variable. Various tools for the assessment of online medical information have been developed and used to assess the ...
Yehia Baligh R BR 1Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 2Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA 3Center for Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 4Department of Medicine, Drexel University College of Medicine, Philadelphia, PA 5Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 6AIDS Activities Coordinating Office, Philadelphia Department of Public Health, Philadelphia, - - 2014
We evaluated 1,359 adults newly diagnosed with HIV in Philadelphia in 2010-2011 to determine if diagnosis site (medical clinic, inpatient setting, counseling and testing center (CTC), correctional facility) impacted time to linkage to care (difference between date of diagnosis and first CD4/viral load). 1,093 patients (80%) linked to care: 86% ...
Yu Mark Shipeng MS Department of Medicine, University of Toledo, 3000 Arlington Ave, Toledo, OH, 43614, USA, - - 2014
The diagnosis of renal artery stenosis (RAS) has become increasingly common in part due to greater awareness of ischemic renal disease and increased use of diagnostic techniques. Over 90 % of RAS cases are caused by atherosclerotic renovascular disease (ARVD). Patients with ARVD are at high risk for fatal and nonfatal ...
Zelante A A Gastroenterology Unit, Department of Medicine University Hospital "Sant'Anna", Ferrara, - - 2014
Inflammatory bowel diseases (IBD) are a group of chronic intestinal conditions characterized by unpredictable course, with periods of flare-ups and remissions suggesting poor adherence to medical therapy. On the other hand adherence is one of the most common reason of failure in the treatment of chronic disease. We have analyzed ...
Goldstein Jennifer N JN *Department of Medicine, Christiana Hospital, Newark, DE †Philadelphia VA Medical Center ‡Department of Medicine, University of Pennsylvania Philadelphia, PA §University of Illinois, Urbana-Champaign, Urbana, IL ∥Philadelphia VA Medical Center, Center for Health Equity and Promotion ¶Department of Family and Community Medicine, University of Pennsylvania, Philadelphia, - - 2014
Vitamins and supplements are the most commonly used form of complementary and alternative medicine in the United States. Growing research suggests that patients substitute vitamins and supplements for their prescription medications. The reasons might include cost of prescription medications and discordant patient and doctor health belief systems. To investigate the ...
Giladi Aviram M AM Ann Arbor, Mich.; and Atlanta, Ga. From the Department of Surgery, Section of Plastic Surgery, University of Michigan Health System; and private - - 2014
Shared medical appointments combine individual patient-physician encounters with a group educational segment. This allows for patients' needs to be addressed individually and for patients to benefit from shared learning. Shared medical appointments enhance knowledge, understanding, and management of disease by providing a variety of perspectives and experiences. In addition, physician-patient ...
Stothard J Russell JR Department of Parasitology,Liverpool School of Tropical Medicine,Liverpool L3 - - 2014
SUMMARY There are many reasons why detection of parasites of medical and veterinary importance is vital and where novel diagnostic and surveillance tools are required. From a medical perspective alone, these originate from a desire for better clinical management and rational use of medications. Diagnosis can be at the individual-level, ...
Jabbal Abhimanyu A Medical student, University of Edinburgh, - - 2014
Currently, medical students are not given specific guidance on how to dress, which allows them to wear what they interpret as being appropriate, which may not always be optimal. Many studies have shown that a doctor's attire can greatly affect the consultation; however, no studies have been carried out for ...
Donaldson Mark M Dr. Donaldson is the director, Pharmacy Services, Kalispell Regional Healthcare, 310 Sunnyview Lane, Kalispell, Mont. 59901-3199, e-mail mdonaldson@krmc.org. Address correspondence to Dr. - - 2014
As North Americans live longer, have more chronic conditions and take more medications, adverse oral events are likely to increase and aggravate the symptoms of Sjögren syndrome (SS). A total of 151 adults who self-reported having SS and who had a mean (standard deviation [SD]) age of 65.8 (11.5) years ...
Waisbourd Michael M Wills Eye Hospital, Glaucoma Research Centre, Philadelphia, Pa.. Electronic address: - - 2014
Poor adherence with glaucoma medications has been well documented. There remains a significant unmet need for a relatively safe intraocular pressure (IOP)-lowering procedure that minimizes or eliminates patient participation, and thus reduce the incidence of treatment failures attributable to nonadherence. Selective laser trabeculoplasty (SLT) offers several advantages: It effectively reduces ...
Ai Amy L AL Florida State University, 2313 University Center, Bldg. C, Tallahassee, FL 32306. - - 2014
Medication therapy management (MTM) is one form of a medication benefit program offered by public and private health providers and insurers. Although the term was first coined in 2003, MTM in its earlier forms has been used since the 1990s as a mechanism to improve health metrics for medically complex ...
Rotondano Gianluca G Division of Gastroenterology & Digestive Endoscopy, Hospital Maresca, ASLNA3sud, Via Montedoro, Torre del Greco 80059, Italy. Electronic address: - - 2014
Acute upper gastrointestinal bleeding (UGIB) is a common gastroenterological emergency. A vast majority of these bleeds have nonvariceal causes, in particular gastroduodenal peptic ulcers. Nonsteroidal antiinflammatory drugs, low-dose aspirin use, and Helicobacter pylori infection are the main risk factors for UGIB. Current epidemiologic data suggest that patients most affected are ...
Solé Meritxell M University of Barcelona, Barcelona, - - 2014
This paper reviews procedures for ensuring that physicians in the European Union (EU) continue to meet criteria for registration and the implications of these procedures for cross-border movement of health professionals following implementation of the 2005/36/EC Directive on professional qualifications. A questionnaire was completed by key informants in 10 EU ...
- - 2014
HIGHLY COMMENDED by the British Medical Association, this third edition of the book has been substantially expanded to include the latest research on healthcare communication.
Russell Randy R Canadian Forces Health Services, 42 Health Services Medical Clinic, Building A-47, Canadian Forces Base Gagetown, PO Box 17000, Station Forces Oromocto, New Brunswick EOG 2PO, - - 2014
Each time a deployed military member has an exacerbation of a pre-existing chronic disease there is a potential risk to mission success, individual health, and the safety of the unit. Currently, North Atlantic Treaty Organization (NATO) member nations employ different approaches to assessing an individual's medical fitness for deployment. To ...
Yetzer Elizabeth E Talbert Medical Group, Anaheim, CA, - - 2014
Purpose: This article focuses on the extensive impairments of stroke and their influence on medication management. The impairments of motor skills due to paralysis-loss of mobility and balance, lack of hand-to-mouth coordination, and difficulty swallowing-are discussed. A future article will discuss sensory impairments of vision, hearing, cognition, comprehension, communication, and ...
Shorter Daryl D Michael E. DeBakey VA Medical Center, Research Service Line , 2002 Holcombe Blvd, Bldg 121, Office 121-137, Houston, TX 77030 , USA +1 713 791 1414 Ext. 24643 ; - - 2014
Introduction: Cocaine use is a global public health concern of significant magnitude, negatively impacting both the individual as well as larger society. Despite numerous trials, the discovery of an effective medication for treatment of cocaine use disorder remains elusive. Areas covered: This article reviews the emerging pharmacotherapies for treatment of ...
Abdul-Sattar Amal B AB Department of Rheumatology and Rehabilitation, Zagazig University, 16 El-Emam Ali St. Villat el Jamaa, Zagazig, Egypt, - - 2014
The aim of the study was to identify the determinants of adherence to medication among Egyptian patients with SLE. A single-center cross-sectional study was conducted among Egyptian patients with SLE. Adherence to medication was measured via The Compliance Questionnaire for Rheumatology-19, and the patients were classified as non-adherers if they ...
Pagano Gennaro G Department of Medicine and Health Sciences, School of Medicine, University of Molise, Campobasso, Italy; Department of Translational Medical Sciences, Federico II University of Naples, Naples, Italy; Department of Neurology, Cedar-Sinai Medical Center, Los Angeles, CA, - - 2014
Constipation is one of most frequent non-motor symptoms of Parkinson's disease (PD) and it may precede the clinical diagnosis of PD by years, with negative effects on quality of life. In contrast to motor features, levodopa is ineffective and possibly detrimental on constipation. Treatment of constipation in PD is non-specific ...
Wöber Christian - - 2014
In this letter, we present the Austrian proposal for diagnostic criteria of refractory chronic migraine and we discuss the consensensus statement of the European Headache Feaderation. We focus in particular on the definition of adequate prophylactic treatment, the management of medication overuse and the requirement for CSF analyses in patients ...
Eaton Cyd K CK University of Georgia, Boston Children's Hospital/Harvard Medical School, Rutgers Cancer Institute of New Jersey, and Children's Healthcare of Atlanta/Emory University School of Medicine - - 2014
 The current study used multiple statistical methods to determine empirically derived and clinically relevant cutoff scores on the Adolescent Medication Barriers Scale (AMBS) and Parent Medication Barriers Scale (PMBS) to detect adolescents and young adults with solid organ transplants who experienced medication nonadherence or negative medical outcomes.  METHODS:  Participants included ...
Swatzyna Ronald J RJ The Tarnow Center for Self-Management, Houston, TX, USA - - 2014
Pharmaco-electroencephalography (Pharmaco-EEG) studies using clinical EEG and quantitative EEG (qEEG) technologies have existed for more than 4 decades. This is a promising area that could improve psychotropic intervention using neurological data. One of the objectives in our clinical practice has been to collect EEG and quantitative EEG (qEEG) data. In ...
Wehmeier Peter M PM Department of Child and Adolescent Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, J5, 68159, Mannheim, Germany, - - 2014
Although the efficacy and tolerability of ADHD medications have been investigated fairly extensively, there are very few data comparing the different types of medication (e.g. psychostimulants, non-stimulants) in terms of medication adherence. The primary research objective of the COMPLY observational study was to evaluate medication adherence (i.e. compliance) over 1 year ...
Tetef Sue - - 2014
Transmucosal is an alternative route for administering medications (ie, dexmedetomidine, midazolam, naloxone) that can be effective for procedural or moderate sedation in patients with special needs when other routes are not practical or are contraindicated. Special needs populations include children, older adults, pregnant and breast-feeding women, and people with disabilities ...
Mooe Thomas T Unit of Medicine, Department of Public Health and Clinical Medicine Umeå University , Umeå , - - 2014
Abstract Background: The prevalence of COPD among individuals with acute coronary syndrome (ACS) is estimated at 5% to 18%, and COPD appears to be a predictor of poor outcome. Diagnosis of COPD has mostly been based on medical records without spirometry. As COPD is largely undiagnosed and misdiagnosed, the prevalence ...
McGowan Bernie B The North Western Rheumatology Unit, Our Lady's Hospital, Manorhamilton, Co. Leitrim, Ireland, - - 2014
To identify adherence and persistence levels with urate-lowering therapies using the national administrative pharmacy claim database. This was a retrospective, pharmacy claims-based analysis of dispensed anti-gout medications on the Irish national HSE-PCRS scheme database between January 2008 and December 2012. Adherence is defined by the medication possession ratio (MPR), and ...
Nieuwlaat Robby R Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton General Hospital campus, Room C3-107, 237 Barton Street East, Hamilton, ON, Canada, L8L - - 2014
People who are prescribed self administered medications typically take only about half their prescribed doses. Efforts to assist patients with adherence to medications might improve the benefits of prescribed medications. The primary objective of this review is to assess the effects of interventions intended to enhance patient adherence to prescribed ...
Strassnig Martin T MT 1Department of Psychiatry,University of - - 2014
Treatment resistance, along with its sibling partial response, remains a common phenomenon in schizophrenia, complicating the disability burden inherent in the disease. Antipsychotic medications are the mainstay of treatment, and treatment resistance has mainly been defined in terms of poor response to antipsychotic medication. At the same time, clozapine, the ...
Mathern Gary W GW Departments of Neurosurgery and Psychiatry & BioBehavioral Medicine, The Mattel Children's Hospital, David Geffen School of Medicine, University of California, Los Angeles, California, - - 2014
From May 20 to September 1 2014, Epilepsia conducted an online survey seeking opinions about the use of medical marijuana and cannabidiol (CBD) for people with epilepsy. This study reports the findings of that poll. The survey consisted of eight questions. Four questions asked if there were sufficient safety and ...
Linsky Amy A Section of General Internal Medicine, VA Boston Healthcare System, Boston, USA; Center for Healthcare Organization and Implementation Research, VA Boston Healthcare System and ENRM Veterans Affairs Medical Center, Boston and Bedford , MA, USA; Section of General Internal Medicine, Boston Medical Center, Boston, USA; Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, USA. Electronic address: - - 2014
While many patients prefer fewer medications, decisions about medication discontinuation involve collaboration between patients and providers. We sought to identify patient perspectives on intentional medication discontinuation in order to optimize medication use. We conducted 20 interviews and two focus groups with a convenience sample of patients (22 men, 5 women; ...
N Diaye Dieynaba S - - 2014
BackgroundTétanos Quick Stick® (TQS) is a test for tetanus immunity screening for wounded patients in emergency departments (EDs), but represents additional costs compared with a medical interview on vaccination history. The study objective was to assess the effectiveness and cost of the TQS in French EDs.MethodsWe performed a model-based analysis ...
Wilens Timothy T Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Bay Cove Human Services, Andrew House Detoxification Center, Quincy, - - 2014
Opioid related morbidity and mortality is heightened in context to the concomitant use of psychotropic medications. The aim of this project was to examine the extent to which opioid dependent patients seeking detoxification are using and misusing specific psychotropic agents. As part of a quality assurance/improvement project, we systematically assessed ...
Laba Tracey-Lea TL The George Institute for Global Health, University of Sydney, Camperdown, NSW, 2010, Australia, - - 2014
Nonadherence is a global problem undermining the cost-effectiveness of evidence-based medications. Aligning treatment choices with patient preferences may promote adherent behaviour: eliciting patient treatment preferences may help resolve the problem of nonadherence. As there is no reliable measure of nonadherent behaviour that can be used to derive preferences, stated-preference techniques ...
Giri Debasis D Department of Computer Science & Engineering, Haldia Institute of Technology, Haldia, 721657, India, - - 2015
It is not always possible for a patient to go to a doctor in critical or urgent period. Telecare Medical Information Systems (TMIS) provides a facility by which a patient can communicate to a doctor through a medical server via internet from home. To hide the secret information of both ...
Walsh Kathleen E KE Department of Pediatrics, Cincinnati Children's Hospital, University of Cincinnati School of Medicine, Cincinnati, Ohio; Departments of Pediatrics, and Meyers Primary Care Institute, Worcester, Massachusetts; - - 2014
Describe rates of adherence for sickle cell disease (SCD) medications, identify patient and medication characteristics associated with nonadherence, and determine the effect of nonadherence and moderate adherence (defined as taking 60%-80% of doses) on clinical outcomes. In February 2012 we systematically searched 6 databases for peer-reviewed articles published after 1940. ...
Goodman Sam S Weymouth House, The Media School, Bournemouth University, BH12 5BB, Fern Barrow, Poole, Dorset, UK, - - 2014
This article examines J. G. Farrell's depictions of colonial medicine as a means of analysing the historical reception of the further past and argues that the end-of-Empire context of the 1970s in which Farrell was writing informed his reappraisal of Imperial authority with particular regard to the limits of medical ...
Schaarschmidt Marthe-Lisa ML Department of Dermatology, University Medical Center Mannheim, Heidelberg University, Mannheim, - - 2014
Evidence on preferences for specific medications is scarce. Here we assessed treatment satisfaction of 200 participants with moderate-to-severe psoriasis from a German University hospital with a 5-point scale and the Treatment Satisfaction Questionnaire for Medication (TSQM) and determined sociodemographic and disease-related influence factors. Participants obtaining biologicals and traditional systemic medications ...
Hsu Clarissa - - 2014
BackgroundIn the United States, more than 25 million people have diabetes. Medication adherence is known to be important for disease control. However, factors that consistently predict medication adherence are unclear and the literature lacks patient perspectives on how health care systems affect adherence to oral hypoglycemic agents (OHAs). This study ...
Scheuner Maren T MT 1] Division of Medical Genetics, Department of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA [2] Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, - - 2014
Purpose:The aim of this study was to survey American College of Medical Genetics and Genomics members about secondary findings from clinical genome-scale sequencing.Methods:A Web-based survey was mailed to 1,687 members of the American College of Medical Genetics and Genomics. Exploratory factor analysis identified underlying factors assessed by survey items. Linear ...
Jones David S DS Department of the History of Science, Harvard University, Cambridge, Massachusetts - - 2014
Historians of medicine have struggled for centuries to make the case for history in medical education. They have developed many arguments about the value of historical perspective, but their efforts have faced persistent obstacles, from limited resources to curricular time constraints and skepticism about whether history actually is essential for ...
Otero María José MJ ISMP-España, Complejo Asistencial Universitario de Salamanca-IBSAL, Salamanca, Spain. Electronic address: - - 2014
Patients with chronic diseases often receive multiple medications and are associated with increased vulnerability to medication errors. Identifying high-alert medications for them would help to prioritize the interventions with greatest impact for improving medication safety. The aim of this study was to develop a list of high-alert medications for patients ...
Binney Nicholas N EGENIS: Centre for the Life Sciences, University of Exeter, Exeter, - - 2014
Medics may consider worrying about their metaphysics and ontology to be a waste of time. I will argue here that this is not the case. Promiscuous realism is a metaphysical position which holds that multiple, equally valid, classification schemes should be applied to objects (such as patients) to capture different ...
Zhou Qi Q *The Children's Hospital of Soochow University †Collaborative Innovation Center of Hematology, Soochow University, Suzhou, - - 2014
In this study, we have analyzed both administrative and clinical data from our hospital during 2002 to 2012 to evaluate the influence of government medical policies on reducing abandonment treatment in pediatric patients with acute lymphoblastic leukemia. Two policies funding for the catastrophic diseases and the new rural cooperative medical ...
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