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Placzek Hilary E D HE Industry Sponsored Research, HealthCore, Inc., Andover, Massachusetts, - - 2014
To determine prior authorization (PA) impact on healthcare utilization, costs, and pharmacologic treatment patterns for painful diabetic peripheral neuropathy (pDPN) and fibromyalgia (FM). This retrospective, observational, longitudinal cohort study used medical and pharmacy claims data. Newly diagnosed patients treated for FM or pDPN between 7/1/2007 and 12/31/2011 were included. PA ...
Adkisson Cameron D CD Division of Endocrine Surgery, University of Pittsburgh School of Medicine, Pittsburgh, - - 2014
Fibromyalgia (FM), an ill-defined symptom complex, is characterized by musculoskeletal pain, headache, depression, fatigue, and cognitive decline, symptoms also seen commonly in primary hyperparathyroidism (PHP). Prevalence of concurrent PHP and FM and response to parathyroidectomy (PTX) of those with both conditions are unknown. We reviewed prospective data of 4,000 patients ...
Reeve Emily E University of South Australia, Adelaide, South Australia, Australia Royal Adelaide Hospital, Adelaide, South Australia, Australia - - 2014
Proton pump inhibitors (PPIs) are inappropriately prescribed in up to 50% of users. Systematic medication review and cessation of inappropriate medications or deprescribing may improve patient outcomes and reduce costs. The aim of this study was to assess the feasibility of a patient-centered deprescribing process in a population of adults ...
Zellweger Ueli - - 2014
Prevalence estimates of chronic medical conditions and their multiples (multimorbidity) in the general population are scarce and often rather speculative in Switzerland. Using complementary data sources, we assessed estimates validity of population-based prevalence rates of four common chronic medical conditions with high impact on cardiovascular health (diabetes mellitus, hypertension, dyslipidemia, ...
Leblanc Richard R Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada; - - 2014
William Howard Feindel (1918-2014) was one of the world's most distinguished neurosurgeons and a brilliant neuroscientist. As the Montreal Neurological Institute's third director, having succeeded Theodore Rasmussen and Wilder Penfield, he proved to be a visionary medical and scientific administrator. His keen interests in epilepsy and brain imaging were enhanced ...
Mathern Gary W GW Departments of Neurosurgery and Psychiatry & BioBehavioral Medicine, The Mattel Children's Hospital, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, - - 2014
From March 19 to June 30, 2014, Epilepsia conducted an open access online survey asking directed questions related to the 2014 Operational Definition of Epilepsy. This study reports the findings of that poll. The survey consisted of seven questions. Three questions addressed: (1) Criteria for when a person could be ...
de Castro J J Oncology Department, La Paz University Hospital, Paseo de la Castellana, 261, 28046, Madrid, Spain, - - 2014
The last decade has seen substantial progress in the diagnostic and therapeutic approach to lung cancer, thus meaning that its prognosis has improved. The Spanish Society of Medical Radiology and the Spanish Society of Medical Oncology have therefore produced a national consensus statement to make recommendations for radiological diagnosis and ...
Duong David K DK Department of Emergency Medicine, University of California, San Francisco, - - 2014
The emergency medicine oral case presentation (EM OCP) is the clinician's communication tool to justify whether urgent intervention is required, to argue for ruling out emergent disease states, and to propose safe disposition plans in the context of triaging patients for medical care and prioritization of resources. The EM OCP ...
Choi Sharon S SS Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, - - 2014
Atherosclerotic renovascular disease is the most common cause of secondary hypertension. The patients with renovascular disease are at increased risk for adverse cardiac outcomes. Recent trials comparing medical therapy alone to medical therapy with stenting are flawed, but lay to rest any existing debate that unselected revascularization is unwarranted; however, ...
Tsai Leo L LL Division of Body MRI, Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215. Electronic address: - - 2014
Splenosis is a completely benign entity that can mimic a primary mass or metastasis. Herein we report the first known case of gallbladder splenosis in a 49-year-old woman with an extensive surgical and medical history. Cross-sectional computed tomography and MRI demonstrated a single mass arising from the gallbladder fundus. Revelation ...
Linnebur Sunny A SA Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, Colorado. Electronic address: - - 2014
Polypharmacy and medication adherence are well known challenges facing older adults. Medication regimen complexity increases the demands of self-care in the home. Some medication regimens may be more complex than others, especially when dosage form, frequency of dosing, and additional usage directions are included in complexity along with the number ...
Safain Mina G MG Department of Neurosurgery, Tufts Medical Center and Tufts University School of Medicine, Boston, - - 2014
Herpes simplex encephalitis (HSE) is a devastating and severe viral infection of the human central nervous system. This viral encephalitis is well known to cause severe cerebral edema and hemorrhagic necrosis with resultant increases in intracranial pressure (ICP). While medical management has been standardized in the treatment of this disease, ...
Willmott Lindy L Australian Centre for Health Law Research, Faculty of Law, Queensland University of Technology, Brisbane, QLD, Australia. - - 2014
Intractable disputes about withholding and withdrawing life-sustaining treatment from adults who lack capacity are rare but challenging. Judicial resolution may be needed in some of these cases. A central concept for judicial (and clinical) decision making in this area is a patient's "best interests". Yet what this term means is ...
Morgan Daniel J DJ Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore2Department of Hospital Epidemiology, Veterans Affairs Maryland Health Care System, - - 2014
Overuse of medical care, consisting primarily of overdiagnosis and overtreatment, is a common clinical problem. To identify and highlight the most significant clinical articles published in 2013 related to medical overuse. A systematic review of English-language articles published in 2013 that related to medical overuse in adults. We reviewed 478 ...
Kimura Michio M Department of Pharmacy, Ogaki Municipal Hospital, Ogaki, Gifu, - - 2014
In the present study, medication adherence and factors affecting adherence were examined in patients taking oral anticancer agents. In June 2013, 172 outpatients who had been prescribed oral anticancer agents by Ogaki Municipal Hospital (Ogaki, Gifu, Japan) completed a questionnaire survey, with answers rated on a five-point Likert scale. The ...
Magura Stephen S The Evaluation Center, Western Michigan University, Kalamazoo MI 49008 - - 2014
Medication non-adherence among psychiatric patients is known to be associated with poorer treatment outcomes. The study examined a comprehensive set of modifiable risk factors for non-adherence in a theoretical framework among a diverse, high risk sample of psychiatric patients with substance misuse histories (N=299). Medication side effects and excessive alcohol ...
Merkx Maarten J M MJ Department of Psychiatry, Amsterdam Institute for Addiction Research, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands, Jellinek Substance Abuse Treatment Center, Amsterdam, the - - 2014
ABSTRACT. Little is known about the incremental effects of medically assisted detoxification on outpatient treatment for alcohol use disorders. The objective of this study was to compare drinking outcomes in a psychosocial treatment program between two groups of heavy drinking patients who had an alcohol use disorder: (a) one group ...
Gelatic Randee R Randee Gelatic is a pharmacist at North Country HealthCare in Flagstaff, Ariz. The author has disclosed no potential conflicts of interest, financial or - - 2014
Recent guidelines on hypertension management offer conflicting recommendations. This article describes the JNC 8 and ASH/ISH guidelines and the four medications recommended for controlling BP in various patient populations.
Levin Jennifer B JB *Department of Psychiatry, Case Western Reserve University School of Medicine; †Neurological and Behavioral Outcomes Center, University Hospitals Case Medical Center; and ‡Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, - - 2014
This analysis compared medication attitudes and reasons for nonadherence in three distinct groups of patients with serious mental illness (SMI). Cohort 1 had 43 patients with bipolar disorder (BD) treated in a community mental health setting, cohort 2 had 43 patients with BD taking an atypical antipsychotic and treated in ...
Mottillo Salvatore - - 2014
Clinical questionWhat is the effect of family presence during cardiopulmonary resuscitation on family members and the medical team?Article chosenJabre P, Belpomme V, Azoulay E, et al. Family presence during cardiopulmonary resuscitation. N Engl J Med 2013;368:1008-18.ObjectiveThe authors sought to determine whether systematically offering relatives the option to be present during ...
Crowley Matthew J MJ Center for Health Services Research in Primary Care, Durham VA Medical Center, HSR&D (152), 508 Fulton Street, Durham, NC, 27705, USA, - - 2014
Medication non-adherence is a major impediment to the management of cardiovascular disease risk factors. A better understanding of the modifying factors underlying medication non-adherence among individuals with known cardiovascular disease may inform approaches for addressing non-adherence. The purpose of this study was to identify demographic and patient characteristics, medical comorbidities, ...
Johnson Björn B a Senior Lecturer, Department of Social Work , Malmö University , Malmö ,, - - 2014
Abstract Opioid substitution treatment (OST) is still controversial, despite positive results. The issue of diversion to the illicit drug market is a cornerstone in the criticism typically voiced against the treatment. Little research is available concerning how professionals who work in OST view the issue of diversion. In this article, ...
Spencer A A Department of General Medicine, Christchurch Hospital, Christchurch, New - - 2014
Prevention of venous thromboembolism (VTE) in medical patients is controversial. In contrast to surgical patients, the evidence supporting the use of heparin-based treatment for prevention of VTE (HVTEp) may not justify current guidelines. This study aims to determine whether current clinical guidelines for HVTEp are appropriate for medical patients. We ...
Boos Stephen C - - 2014
Medical neglect occurs when children are harmed or placed at significant risk of harm by gaps in their medical care. This is most likely to occur and to be recognized when families lack resources, commonly due to poverty, and when medical demands are high, such as with complex, severe, and ...
Berntorp E E Malmö Centre for Thrombosis and Haemostasis, Lund University, Malmö, - - 2014
At the 7th Annual Congress of the European Association for Haemophilia and Allied Disorders (EAHAD) held in Brussels, Belgium, in February 2014, Pfizer sponsored a satellite symposium entitled: "Pharmacokinetics, phenotype and product choice in haemophilia B: How to strike a balance?" Co-chaired by Cedric Hermans (Cliniques Universitaires Saint Luc, Brussels, ...
Magid Michelle M MAGID: University of Texas Southwestern Medical Center, Austin; TREVINO: University of Texas Southwestern Medical Center, Dallas; REID: Clinical and Forensic Psychiatrist, Horseshoe Bay, TX; JALALAT: University of Texas Medical Branch, Galveston; HUSAIN: University of Texas Southwestern Medical Center and Duke University, Durham, NC; KAHN: Columbia University College of Physicians and Surgeons, New - - 2014
Electroconvulsive therapy (ECT) is infrequently considered an "emergency" medical procedure; however, there are certain conditions in which there is considerable urgency to initiate ECT. For example, prompt administration of ECT to treat neuroleptic malignant syndrome and malignant catatonia is necessary to improve a patient's overall prognosis and potentially save the ...
Kearns Marcia A MA KEARNS and HAWLEY: Department of Psychological Sciences, University of Missouri, - - 2014
We employed a national survey of child psychiatrists to examine typical prescribing practices for children with anxiety, depression, and disruptive behavior disorders. We examined the extent to which polypharmacy and off-label prescribing occur in routine practice and the degree to which child characteristics, child psychiatrist characteristics, and medication availability may ...
Convers Kathryn D KD Saint Louis University, St Louis, Missouri. Electronic address: - - 2014
In 1971, we published a survey regarding pediatricians' attitudes toward the field of allergy/immunology (A/I). Results indicated general attitudes and practices fell short of what most allergist-immunologists would hope. We revisited this in 1998 to determine how pediatricians' attitudes toward A/I had changed nearly 3 decades later. Despite some advances, ...
Marugg Lindsey L Boonshoft School of Medicine, Wright State University, Dayton, OH, - - 2014
The traditional ethical model of the "Four-Box Method" can be adapted to integrate the perspective of a Catholic physician. In an increasingly secularist environment, medical students and physicians are often asked to "leave religious beliefs at the door" and not consider the care and stewardship of our own morality and ...
Tanna Sangeeta S Leicester School of Pharmacy, Faculty of Health & Life Sciences, De Montfort University, The Gateway, Leicester, LE1 9BH, - - 2014
Little research using dried blood spot samples to assess adherence to medication has been reported. The World Health Organisation estimates that only half of the patients in the developed world take their medication as prescribed. Additional costs to the healthcare provider include wasted medicines, avoidable additional hospital visits and non-optimum ...
Wei Yu-Jung YJ Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD, USA. Electronic address: - - 2014
To examine 1) the effect of prior antiparkinson drug (APD) nonadherence on subsequent APD regimen modifications; and 2) the influence of modifications on healthcare utilization and costs by patients with Parkinson's disease (PD). This retrospective cohort study included 7052 PD patients with ≥2 APD prescriptions who initiated a modification of ...
- - 2014
Disclaimer: These recommendations are designed primarily as an educational resource for medical geneticists and other health-care providers to help them provide quality medical genetics services. Adherence to these recommendations does not necessarily ensure a successful medical outcome. These recommendations should not be considered inclusive of all proper procedures and tests ...
Hawasli Ammar H AH Department of Neurosurgery, Washington University School of Medicine, St. Louis, Mo., - - 2014
Since its introduction to neurosurgery in 2008, laser ablative techniques have been largely confined to the management of unresectable tumors. Application of this technology for the management of focal epilepsy in the adult population has not been fully explored. Given that nearly 1,000,000 Americans live with medically refractory epilepsy and ...
Varghese J J Julian Varghese, University of Muenster, Institute of Medical Informatics, Albert-Schweitzer-Campus 1, Gebäude A11, 48149 Münster, Germany, E-mail: - - 2014
Background: Eligibility criteria (EC) of clinical trials play a key role in selecting appropriate study candidates and the validity of the outcome of a clinical trial. However, in most cases EC are provided in unstandardised ways such as free text, which raises significant challenges for machine-readability. Objectives: To establish a ...
Tullo Ellen StClair ES a Institute for Ageing and Health, Biomedical Research Building, Campus for Ageing and Vitality , Newcastle University , Newcastle-upon-Tyne , - - 2014
Objectives: Care of patients with dementia raises challenging ethical issues, including the use of deception in clinical practice. This study aimed to determine the extent to which medical students agree that ethical arguments for and against deceiving patients in general apply to patients with dementia. Method: Qualitative study using six ...
Witzel Sarah J SJ Saskatoon Co-op Pharmacy , Saskatoon, Saskatchewan, Canada - - 2014
Abstract Biologic medications are effective therapeutic options for treating autoimmune diseases, but information on their safety in lactation is still scarce. Autoimmune conditions occur frequently in women of childbearing age, creating difficult decisions regarding optimizing maternal health and supporting breastfeeding. Available data, in addition to the favorable pharmacokinetic properties of ...
Wise Qc Ian I Doughty Street Chambers (now of Monckton Chambers, Raymond Buildings, - - 2014
Consideration of recent judgment of the Supreme Court in leading case concerning the withdrawal and withholding of medical treatment for a patient lacking capacity who was in a critical condition.
Jones Christopher W - - 2014
Publication bias is a major threat to the validity of systematic reviews. Searches of clinical trials registries can help to identify unpublished trials, though little is known about how often these resources are utilized. We assessed the usage and results of registry searches reported in systematic reviews published in major ...
Ashraf Bushra B Department of Obstetrics and Gynecology, Mother and Child Health Centre, Pakistan Institute of Medical Sciences, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, - - 2014
The Surgical Informed Consent (SIC) is a comprehensive process that establishes an information-based agreement between the patient and his doctor to undertake a clearly outlined medical or surgical intervention. It is neither a casual formality nor a casually signed piece of paper. The present study was designed to audit the ...
Burri Emanuel E Department of Gastroenterology, University Medical Clinic, Cantonal Hospital, Rheinstrasse 24, 4410, Liestal, Switzerland, - - 2014
Non-invasive monitoring of inflammatory bowel disease is an unmet clinical need as patients in clinical remission may have residual mucosal inflammation preceding clinical relapse. We aimed to assess the value of fecal calprotectin and standardized clinical activity scoring to monitor disease activity in ulcerative colitis under medical treatment. Forty-one patients ...
Voils Corrine I - - 2014
BackgroundPatients with multiple chronic conditions often have multiple prescribers, which has been associated with greater health care utilization and medication nonadherence in claims-based analyses. This qualitative study was conducted to understand the reasons why patients have increasing numbers of prescribers of medications and to understand patient perspectives on advantages and ...
Barnes Kelli D KD Division of Pharmacy Practice and Administration, The Ohio State University College of Pharmacy, Columbus, - - 2014
The purposes of this population management intervention were to identify patients with stage 3, 4, or 5 chronic kidney disease (CKD) and to improve care in a patient-centered medical home (PCMH). Objectives of the intervention were to (i) increase the identification of CKD, (ii) increase the use of aspirin and ...
Cournoyea Michael M Institute for the History and Philosophy of Science and Technology, University of Toronto, Toronto, ON, - - 2014
In this paper, we propose a methodology for investigating medically unexplained physical symptoms (MUPSs). These symptoms are common in both primary and specialist medical practices, but are poorly understood. Currently, MUPSs are diagnosed via non-explanatory labels. However, we show that explanatory diagnoses are preferable to non-explanatory syndromic diagnoses because they ...
Carpenter Delesha M DM Division of Pharmaceutical Outcomes and Policy, University of North Carolina, Asheville, USA. Electronic address: - - 2014
We describe the medication information-seeking behaviors of arthritis patients' partners and explore whether partner medication information-seeking and information-sharing are associated with patient medication adherence. Arthritis patients and their partners (n=87 dyads) completed an on-line questionnaire. Partners indicated how often they obtained medication information from 14 sources, how much they trusted ...
Brain Cecilia C Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, University of Gothenburg, Sweden; Psychosis Clinic, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address: - - 2014
The aims of this naturalistic non-interventional study were to quantify the level of stigma and discrimination in persons with schizophrenia and to test for potential associations between different types of stigma and adherence to antipsychotics. Antipsychotic medication use was electronically monitored with a Medication Event Monitoring System (MEMS(®)) for 12 ...
Lamanna J J Department of Psychology, Virginia Commonwealth University, Richmond, VA, - - 2014
This qualitative, exploratory study examines the content of communication between healthcare providers (HCP) and childhood cancer patients (CCP) during a medical appointment to evaluate the extent to which cancer survivorship issues (medical and psychosocial) are discussed. The content of the communication for 16 CCP ages 10-22 and their HCP were ...
Kröger K K Klinik für Gefäßmedizin, HELIOS Klinik Krefeld, Krefeld, Germany; Thrombose-Initiative e.V., Mainz, - - 2014
Despite the existence of active prophylaxis strategies for patients at risk of venous thromboembolism (VTE), people still suffer from this disease. To establish the setting in which VTE occurs and how it can be prevented, a study was conducted aimed at analysing the circumstances surrounding VTE development. In a nationwide ...
Diaconu Karin - - 2014
Medical device procurement processes for low- and middle-income countries (LMICs) are a poorly understood and researched topic. To support LMIC policy formulation in this area, international public health organizations and research institutions issue a large body of predominantly grey literature including guidelines, manuals and recommendations. We propose to undertake a ...
Cobb Carla D CD RiverStone Health Clinic, Billings, - - 2014
Our objective was to evaluate a pharmacist-delivered comprehensive medication management (CMM) service provided to patients with psychiatric disorders. We conducted a retrospective review and analysis of medication-related data, and a return on investment cost analysis. The project consisted of 154 patients with psychiatric disorders who were referred to the CMM ...
Austin Stephen S Melbourne Dental School, University of Melbourne, Victorian/Tasmanian Oral & Maxillofacial Training - - 2014
The population seeking implants in private practice is a demographically and medically unique group. Understanding their medical needs can improve treatment planning and service delivery specifically for this population. Privately practicing dental clinicians from Victoria, Australia, participated in a 5 year retrospective study. Data was collected from the medical histories ...
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