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Claydon-Platt Kate K PhD Researcher, Melbourne School of Health Sciences, The University of Melbourne, Level 6, Alan, Gilbert Building, 161 Barry Street, Carlton Victoria Australia 3010. Phone: +61 3 8344 9463, Fax: +61 3 8344 5391 Email: - - 2014
Abstract Aims: To develop and evaluate a screening tool to identify people with diabetes at increased risk of medication problems relating to hypoglycaemia and medication non-adherence. Methods: A retrospective audit of attendances at a diabetes outpatient clinic at a public, teaching hospital over a 16-month period was conducted. Logistic regression ...
Touma Waseem W Division of Hospital Medicine, Department of Internal Medicine, St. Louis, MO, United - - 2014
Cetuximab, a chimeric monoclonal antibody, is the only targeted therapy approved for squamous cell carcinoma of the head and neck (SCCHN). Infusion reactions (IRs) occur in 6-18% of patients pre-medicated with diphenhydramine. Evidence for clinical risk factors for IRs is limited and the benefit of additional pre-medication to prevent IRs ...
Chapman Christopher G CG Inflammatory Bowel Disease Center, University of Chicago Medicine, 5841 South Maryland Avenue, MC 4076, Chicago, IL 60637, - - 2014
It has been proposed that effective disease control through abrogation of inflammation in IBD may also reduce CRC risk in these individual patients. This article summarizes the potential for medical therapy to reduce the risk of CRC via primary and secondary prevention, and offers practical ways in which a goal ...
Kitzman Patrick - - 2014
Objective The purpose of this study was to examine the overall prevalence of polypharmacy within the spinal cord injury (SCI) population, the level of polypharmacy with respect to seven classes of high-risk drugs commonly used to treat secondary conditions in the SCI population, and the overall risks for drug-related problems ...
Willen Shaina M SM Department of Pediatrics, Duke University Medical Center, Durham, NC, - - 2014
Sickle cell disease (SCD) is the most common genetic disease among persons with African ancestry. This article provides a background to SCD and reviews many important aspects of travel preparation in this population. The medical literature was searched for studies on travel-associated preparedness and complications in individuals with SCD. Topics ...
Renata Grou Volpe Cris C Associate Professor of Nursing; University of Brasilia, - - 2014
This article describes the analysis of the frequency, type and risk factors relating to errors in the preparation and administration of medications in patients admitted to a public hospital in Brasilia Federal District, Brazil, which serves a population of approximately 500,000 inhabitants. Patients are commonly affected and harmed by medication ...
Urkin Jacob J Division of Community Health, Department of Family Medicine and Siaal Research Center for Family Practice and Primary Care, Faculty of Health Sciences, Ben-Gurion University of the Negev, P.O. Box 653, 84105, Beer-Sheva, Israel, - - 2014
Religiosity is inherent in human cultures. Being different in many aspects, all have rules regarding appropriate behavior and rituals. Celebrations of social events and of holidays prevail in all major religions. These include code of dress, prayers, special food and activities which may have negative health implications. The Jewish religion ...
Rome Benjamin N BN Program On Regulation, Therapeutics, And Law (PORTAL), Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, 1620 Tremont St., Suite 3030, Boston, MA, 02120, USA, - - 2014
Since 1976, the US Food and Drug Administration (FDA) has used the premarket approval (PMA) process to approve high-risk medical devices, including implantable cardioverter defibrillators (ICDs), coronary stents, and artificial heart valves. The PMA process is widely viewed as a rigorous evaluation of device safety and effectiveness, though recent recalls-most ...
Schwabe Karen K Clinical Sport and Exercise Medicine Research Group, UCT/MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, , Cape Town, South - - 2014
The half-marathon (21 km) race is a very popular mass community-based distance running event. It is important to determine risk factors for medical complications during these events, so that prevention programmes can be developed. To determine risk factors associated with medical complications during 21 km road running events. Prospective study. ...
Schwabe Karen K Clinical Sport and Exercise Medicine Research Group, UCT/MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, , Cape Town, South - - 2014
It is important to identify risk factors associated with medical complications during ultra-marathons so that prevention programmes can be developed. To determine risk factors for medical complications during ultra-marathons. Prospective study. Two Oceans ultra-marathon (56 km) races. 26 354 race starters. Medical complications (defined as any runner requiring assessment by ...
Schnabel Marco Julius MJ University of Regensburg, Urology , Caritas Krankenhaus St. Josef , Landshuterstrasse 65 , Regensburg, Germany, 93053 ; - - 2014
Introduction: Shock wave lithotripsy (SWL) is the gold standard treatment of most renal and proximal ureter calculi. Severe bleeding complications in SWL are extremely rare. Uncorrected bleeding diathesis might increase the risk and is considered to be an absolute contraindication for SWL. Objective: Perioperative management of anticoagulative and antiplatelet therapy ...
Gendron Nicolas N Assistance Publique Hôpitaux de Paris, Service de Bactériologie, Centre National de Référence des Streptocoques, Hôpitaux Universitaires Paris Centre Cochin-Broca-Hôtel Dieu, Paris, - - 2014
Medical abortion is not recognized as a high risk factor for invasive pelvic infection. Here we report two cases of Group A Streptococcus (Streptococcus pyogenes; GAS) endometritis following medical abortions with a protocol of oral mifepristone and misoprostol.
Reich James J Department of Psychiatry, University of California, San Francisco, San Francisco, California, USA. E-mail: - - 2014
Our objective is to compare legal difficulties that psychiatrists encounter in regulatory agency and malpractice (insurance) settings. Data sources included a literature search of malpractice and medical board discipline from 1990 to 2009 (rates and types of discipline); publicly available insurance data (malpractice frequency and type); and data from the ...
Rojas-Fernandez Carlos H CH Schlegel-University of Waterloo Research Institute for Aging (Rojas-Fernandez, Brown), University of Waterloo, Waterloo, - - 2014
One-third to one-half of adults older than 65 fall at least once per year. Fall prevention through medication management requires little effort and has consistently been shown to reduce risk of falls. The objective of this study was to further develop and perform preliminary pilot testing of an algorithm designed ...
Katz Daniel H DH 1Department of Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, - - 2014
With the release of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults, emphasis has been placed on using evidence-based intensity of therapy to reduce atherosclerotic cardiovascular disease (ASCVD) risk, rather than focusing on goal cholesterol ...
Fontana Marianna M International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, London, United - - 2014
Primary prevention guidelines focus on risk, often assuming negligible aversion to medication. Yet most subjects discontinue primary prevention statins within 3 years. We quantify real-world distribution of medication disutility, and separately calculate average utilities for a range of risk strata. We randomly sampled 360 members of the general public in ...
Huo Xiang X Department of Virology, Tohoku University Graduate School of Medicine, Sendai, Japan; Department of Acute Infectious Disease, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, - - 2014
Influenza remains one of the most important causes of respiratory infection despite the widespread availability of vaccines. Anti-influenza viral agents such as neuraminidase inhibitors are generally efficacious in alleviating the symptoms if they are administered within 2 days of the illness onset. However, few studies have examined the situation of ...
Kildare Leanne L Valley Family Medicine, Renton, WA, - - 2014
Both medications reduce the incidence of cardiovascular events in patients with hypertension, but chlorthalidone may confer additional cardiovascular risk reduction.
Carlson Josh J JJ Pharmaceutical Outcomes Research and Policy Program, University of Washington, Box 357630, Seattle, WA, 98195-7630, USA, - - 2014
Our objective was to identify and characterize publicly available cases and related trends for performance-based risk-sharing arrangements (PBRSAs). We performed a review of PBRSAs over the past 20 years (1993-2013) using available databases and reports from colleagues and healthcare experts. These were categorized according to a previously published taxonomy of scheme ...
Pankhurst T T Department of Nephrology, Queen Elizabeth Hospital Birmingham, Birmingham, - - 2014
Background/Aims: Acute kidney injury (AKI) following admission to hospital is associated with increased mortality, morbidity and length of stay. Factors that predispose patients to AKI frequently co-exist. The precise description of their representation in unselected admissions could help define mechanistic inter-relationships and optimise risk stratification strategies. Our aim was therefore ...
Daloiso V V Institute of Bioethics, "A. Gemelli" School of Medicine, Università Cattolica del Sacro Cuore, Rome, - - 2014
The aim of this preliminary survey was to picture the current knowledge and opinions of law students and medical students about nanotechnologies. Data were collected in June 2012 by interviews with 60 students of the University of Camerino (Macerata, Italy) defined as "jurist population" and 159 medical students of the ...
Falconer Nazanin N Nazanin Falconer, B.Pharm., PGCert, is Medication Safety Pharmacist; Sanjoy Nand, B.Pharm., M.Pharm., is Pharmacy Service Manager; Doreen Liow, B.Pharm., M.B.A., PGDip, is Clinical Pharmacy Manager; and Mary Seddon, M.B.Ch.B., is Clinical Director, Centre for Quality Improvement, Middlemore Hospital, Auckland, New Zealand. Aaron Jackson, B.Pharm., is Medication Management Manager, Orion Health, - - 2014
A software-based tool to help prioritize inpatients for adverse drug event (ADE) prevention initiatives is described. The clinical pharmacy department of a New Zealand hospital developed the Assessment of Risk Tool (ART), an application for monitoring prespecified clinical "flags" (some derived from the Institute for Healthcare Improvement's ADE trigger tool) ...
Gonzales Kelly K From the University of Nebraska Medical Center College of Nursing, Nebraska Medical Center, Omaha, - - 2014
To examine the relationship between risk propensity and safe medication administration, while also providing additional evidence of validity and reliability on the Safe Administration of Medication (SAM) Scale. A convenience sample of nursing students from a private Midwest university in the United States was invited to participate in the study. ...
Hall Joseph L - - 2014
The success of telehealth could be undermined if serious privacy and security risks are not addressed. For example, sensors that are located in a patient's home or that interface with the patient's body to detect safety issues or medical emergencies may inadvertently transmit sensitive information about household activities. Similarly, routine ...
Collins C Scott CS Division of General Internal Medicine, Mayo Clinic, Rochester, MN. - - 2014
The number, age, and medical complexity of patients undergoing elective noncardiac surgery is rising worldwide. Internists, family physicians, and midlevel providers asked to perform preoperative medical evaluations. However, lack of consensus has led to wide variation in practice in what is included and addressed in these evaluations, and the efficacy ...
Nelson Lewis S LS Department of Emergency Medicine, New York University School of Medicine, New York City Poison Control Center, 455 First Avenue, Room 123, New York, NY, 10016, USA, - - 2014
The decision to approve a drug for clinical use is based on an understanding of its benefits versus the risks. Although efficacy is generally understood at the time of submission to the FDA for approval, the risks are more difficult to assess. Both PubMed (from 2000 to 2012) and the ...
Cooper William O WO Departments of - - 2014
OBJECTIVES:Recent data showing possible increased risk for suicidal behavior among children and adolescents treated with selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) antidepressants have created significant concern among patients, families, and providers, including concerns about the risk of individual antidepressants. This study was designed to compare the ...
Hegarty Francis J - - 2014
Medical device interoperability has been identified as a key way of decreasing healthcare costs while improving patient care. 1 This has led to a shift toward placing more medical devices onto information technology (IT) networks. However, placing medical devices onto an IT network may lead to additional risks to safety, ...
Girela E E Department of Legal and Forensic Medicine, Faculty of Medicine, University of Córdoba, Avenida Menéndez Pidal s/n, 14071 Córdoba, - - 2014
We have studied the use of coercive medical measures (forced medication, isolation, and mechanical restraint) in mentally ill inmates within two secure psychiatric hospitals (SPH) and three regular prisons (RP) in Spain. Variables related to adopted coercive measures were analyzed, such as type of measure, causes of indication, opinion of ...
Makowsky Mark J MJ Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, - - 2014
Pharmacists working in primary care clinics are well positioned to help optimize medication management of community-dwelling patients who are at high risk of experiencing medication-related problems. However, it is often difficult to identify these patients. Our objective was to test the feasibility of a self-administered patient survey, to facilitate identification ...
Rees Christen C Roche Diagnostics Operations, Indianapolis, IN, USA christen.rees@gmail.com - - 2014
Several studies have shown the usefulness of an automated insulin dose bolus advisor (BA) in achieving improved glycemic control for insulin-using diabetes patients. Although regulatory agencies have approved several BAs over the past decades, these devices are not standardized in their approach to dosage calculation and include many features that ...
Redd Andrew A University of Utah, Department of Internal Medicine, Division of - - 2014
Early warning indicators to identify US Veterans at risk of homelessness are currently only inferred from administrative data. References to indicators of risk or instances of homelessness in the free text of medical notes written by Department of Veterans Affairs (VA) providers may precede formal identification of Veterans as being ...
Bozzato Silvia - - 2013
Acutely ill medical patients may be at increased risk of venous thromboembolism, both during hospitalization and after discharge. International guidelines recommend thromboprophylaxis for high-risk medical patients with low bleeding risk for a maximum of 14 days. There are two approaches to identify the high-risk patient: adhering to the inclusion criteria ...
Nelson D Alan - - 2013
No evidence-based mechanism currently exists to inform U.S. Army clinicians of soldiers at risk of being found "Medically Not Ready" for combat duty. Historically, musculoskeletal conditions represent high-frequency medical problems among Army soldiers. We explored the feasibility of using centrally archived medical and administrative data on Army soldiers in the ...
Gupta Rishu - - 2013
Medications are commonly used during pregnancy; in fact, female patients take an average of 2.9 medications during pregnancy. Due to this high prevalence, malpractice litigation poses a high legal risk to dermatologists who prescribe medications to female patients who are or may become pregnant. This article introduces the medicolegal risks ...
Lee Michael J - - 2013
The possibility and likelihood of a post-operative medical complication after spine surgery undoubtedly play a major role in the decision making of the surgeon and patient alike. While prior study has determined Relative Risk and Odds Ratio values to quantify risk factors, these values may be difficult to translate to ...
Harmon John P - - 2013
Atrial fibrillation and cardiovascular death are increased in end-stage renal disease (ESRD) patients compared to the general population. The effect of anticoagulant and antiplatelet medications for these indications in ESRD is unclear. However, both classes of medications have been used for the preservation of vascular access. This review explores the ...
Newcomer John W - - 2013
The purpose of this project was to provide evidence-based guidance concerning when and how it is appropriate to undertake elective changes in antipsychotic medications in order to reduce adverse effects, with a focus on those adverse effects associated with increased long-term health risks. This project extends the results of the ...
Thongbai Thirada T Department of Medicine, Bangkok Metropolitan Administration General Hospital, Bangkok, Thailand. - - 2013
Aspirin is a widely used medication for primary and secondary prevention of cardiovascular and cerebrovascular events. The gastrointestinal risks of aspirin are well known, but the frequency of gastroduodenal mucosal injuries in aspirin users in Thailand is currently unknown. The present study was performed to investigate the prevalence of gastroduodenal ...
Norris Beverley - - 2013
A multi-disciplinary approach to designing safer healthcare was utilised to investigate risks in the bed-space in elective surgical wards. The Designing Out Medical Error (DOME) project brought together clinicians, designers, psychologists, human factors and business expertise to develop solutions for the highest risk healthcare processes. System mapping and risk assessment ...
Okada Yasushi - - 2014
Since transient ischemic attack (TIA) is regarded as a medical emergency with high risk for early stroke recurrence, the underlying mechanisms should be immediately clarified to conclude a definitive diagnosis and provide early treatment. Early risk stratification using ABCD(2) scores can predict the risk of ischemic stroke occurring after TIA. ...
Davidson Jaime A JA Division of Endocrinology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd. K5.246, Dallas, TX, 75235-8857, USA, - - 2013
Type 2 diabetes is associated with a high prevalence of comorbidities resulting from hypertension, dyslipidemia, and hyperglycemia. Inadequate management of these risk factors will eventually result in detrimental health consequences. Thus, the effect of a drug on factors such as weight, cardiovascular (CV) risk factors, and adherence is important to ...
Harrison Donald C DC Department of Medicine, University of Cincinnati Academic Health Center, Cincinnati, Ohio. Electronic address: - - 2013
The 20-year activities of a medical supervisory panel appointed under the terms of a settlement agreement of the Bowling v. Pfizer class action suit involving the Björk-Shiley convexo-concave (BSCC) heart valve are detailed. Of approximately 86,000 valves implanted, catastrophic failure of the valve was reported in 663 patients from 1978 ...
Gillette Chris - - 2013
The objectives of this study were to: (1) describe the extent to which general pediatric providers discuss risks associated with asthma control medications with families, and (2) examine factors that are associated with risk discussions. This study was a cross-sectional secondary analysis of audio taped medical visits involving 35 pediatric ...
Kelly Aaron S - - 2013
Severe obesity afflicts between 4% and 6% of all youth in the United States, and the prevalence is increasing. Despite the serious immediate and long-term cardiovascular, metabolic, and other health consequences of severe pediatric obesity, current treatments are limited in effectiveness and lack widespread availability. Lifestyle modification/behavior-based treatment interventions in ...
Adachi Kenji - - 2013
Background. Pre-travel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the health consultation associated with malaria prevention provided to U.S. travelers bound for West Africa. Methods. The estimated change in disease risk and associated costs and ...
Porter Emily B - - 2013
Figure skating continues to increase in popularity as both a recreational and competitive sport. Skaters continue to "push the envelope" in perfecting more technically difficult skills. With their strenuous training programs, skaters are at risk from chronic overuse injuries, which tend to plague singles skaters more often than acute injuries. ...
Thomas Maria - - 2013
An effective intervention to decrease medication errors related to high-risk, high-alert medications is to implement double checks and second verification using the five rights of medication administration. To evaluate the effectiveness and use of the Personalized Bar-Code Identification card in verifying high-risk, high-alert medications, the High-Risk, High-Alert Medication Verification Audit ...
Dupnik Kathryn Margaret KM Division of Infectious Diseases and Center for Global Health, Weill Cornell Medical College, New York, NY, - - 2013
The objective was to characterise and identify potential risk factors for intolerance to multi-drug leprosy therapy (MDT) which prompted a medication change in a leprosy referral centre in northeastern Brazil. A retrospective chart review of leprosy patients treated at a state referral centre for leprosy in Natal, Rio Grande do ...
Zipursky Robert B - - 2013
The large majority of individuals with a first episode of schizophrenia will experience a remission of symptoms within their first year of treatment. It is not clear how long treatment with antipsychotic medications should be continued in this situation. The possibility that a percentage of patients may not require ongoing ...
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