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Weng M-C - - 2013
Summary BACKGROUND: Older patients with chronic diseases often take multiple prescription drugs, increasing their risk of adverse health events. However, polypharmacy remains ill-defined. To investigate the impact of number of drugs prescribed on potentially inappropriate medication (PIM) and the associated risk factors in older outpatients with chronic diseases. Retrospective cross-sectional ...
Schwarz Eleanor Bimla EB Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. - - 2013
Medications that may increase risk of birth defects if used during pregnancy or immediately preconception are dispensed to approximately half of female Veterans who fill prescriptions at a VA pharmacy. To assess receipt of counseling about risk of medication-induced birth defects among female Veterans of reproductive age and to examine ...
Messano G A - - 2013
Malpractice is the responsible for the greatest number of legal claims. At the present time, legal actions against physicians in Italy are 15,000 per year, and a stunning increase about costs to refund patients injured by therapeutic and diagnostic errors is expected. The method for the medical prevention is "Risk ...
Ojeleye Oluwagbemileke - - 2013
Electronic Patient Medication Record (ePMR) systems have important safety features embedded to alert users about potential clinical hazards and errors. To date, there is no synthesis of evidence about the effectiveness of these safety features and alerts at the point of pharmacy order entry. This review aims to systematically explore ...
Cranford James A JA Addiction Research Center, Department of Psychiatry, University of Michigan, Rachel Upjohn Building, 4250 Plymouth Road, Ann Arbor, MI 48109-2700, USA. - - 2013
The purpose of this study was to identify subgroups of adolescents based on their past 12 months use of tobacco, alcohol, marijuana, illicit drugs, and nonmedical use and excessive medical use of prescription medications. A cross-sectional Web-based survey of adolescents from two middle and high school districts in Southeastern Michigan ...
Woods Scott W SW Department of Psychiatry, Yale University, New Haven, CT, United States. - - 2013
Antipsychotic medication use rates have generally been rising among youth with psychiatric disorders, but little is known about use rates of antipsychotics or other psychotropic medications in patients at high risk for psychosis. Baseline psychotropic medication use rates were compared in two research cohorts of patients at high risk for ...
Bailey Genie L - - 2013
Most patients with opioid addiction do not receive medication at the time of discharge from brief inpatient detoxification programs despite the high risk of relapse and the availability of three FDA-approved medications. We surveyed 164 inpatient opioid detoxification patients to assess desire for pharmacotherapy following detoxification program discharge. Participants were ...
Teunissen Rick - - 2013
The clinical relevance of and risk factors associated with errors related to medication administration time were studied. In this explorative study, 66 medication administration rounds were studied on two wards (surgery and neurology) of a hospital. Data on medication errors were collected using the blister collection method. The emptied packaging ...
Goldman Dana - - 2013
Medical expenses are an increasingly important contributor to household financial risk. We examine the effect of medical expenditure risk on the willingness of Medicare beneficiaries to hold risky assets. Using a discrete factor maximum likelihood method to address the endogeneity of insurance choices, we find that having a moderately protective ...
Claes Neree - - 2013
BACKGROUND: Cardiovascular disease is a major cause of mortality and morbidity and its prevalence is set to increase. While the benefits of medical and lifestyle interventions are established, the effectiveness of interventions which seek to improve the way preventive care is delivered in general practice is less so. The aim ...
Liao P-J - - 2013
The aim of this study was to explore the factors associated with the occurrence, subsequent prognoses and need for additional medications following cutaneous adverse drug reactions (ADRs) among inpatients. This is a case-control study, nested in a large cohort study of 473,446 inpatients hospitalised from 2005 to 2008, examined cutaneous ...
Caprio Fan Z - - 2013
Intracranial atherosclerotic disease (ICAD) is one of the most common causes of ischemic stroke worldwide and is associated with a high risk of recurrent stroke despite aggressive therapy. ICAD may lead to cerebral ischemia through a variety of mechanisms, the interactions of which are largely unknown. The use of endovascular ...
Murphy Mary P - - 2013
PURPOSE: Falls are a challenge for rehabilitation nurses, facilities, families, and individuals. Studies related to the causes of falls and potential strategies for risk management have been conducted across disability groups and with the elderly. Still, a focus on individuals with traumatic brain injuries (TBI), specifically, has been limited. This ...
Merkel Reinhard R Faculty of Law, University of Hamburg, Rothenbaumchaussee 33, Hamburg 20148, Germany. - - 2013
Non-therapeutic circumcision violates boys' right to bodily integrity as well as to self-determination. There is neither any verifiable medical advantage connected with the intervention nor is it painless nor without significant risks. Possible negative consequences for the psychosexual development of circumcised boys (due to substantial loss of highly erogenous tissue) ...
Hübner Nils-Olaf - - 2013
BACKGROUND: The use of examination gloves is part of the standard precautions to prevent medical staff from transmission of infectious agents between patients. Gloves also protect the staff from infectious agents originating from patients. Adequate protection, however, depends on intact gloves. The risk of perforation of examination gloves is thought ...
Al-Turkistani Hatim K - - 2013
Discharging patients against medical advice is a problem of every age-group. However, because of their physiological vulnerability, the risk for the neonatal population is greater when discharged against medical advice (DAMA). This article is a study of the prevalence of the problem, the possible causes and/or risk factors. A retrospective ...
Brett Hauber A - - 2013
Decisions regarding the development, regulation, sale, and utilization of pharmaceutical and medical interventions require an evaluation of the balance between benefits and risks. Such evaluations are subject to two fundamental challenges-measuring the clinical effectiveness and harms associated with the treatment, and determining the relative importance of these different types of ...
Roberts Charles G - - 2013
Biofilms are communities of microorganisms within extracellular polymeric material attached to surfaces. Within a biofilm, cells have some protection from drying and other stress factors in their environment, including antimicrobial agents. In this article, the challenges to medical device reprocessing posed by biofilms are addressed. Biofilm formation on reusable medical ...
Kupensky Diane T - - 2013
Depression is on the rise, and as a result, there is an increased use of psychotropic medications. Also, nonreversible anticoagulants have entered the market and are increasing in use. In combination, these developments have created new risk factors for trauma patients. Our study examined the occurrence of trauma patients who ...
Sudzinova A - - 2013
OBJECTIVES: Coronary heart disease (CHD) is the most common cause of mortality and morbidity world-wide. Evidence on ethnic differences between the Roma and non-Roma regarding medical risk factors is scarce. The aim of this study was to assess differences in medical risk factors and the severity of CHD in Roma ...
McCusker Jane - - 2013
To identify potentially modifiable environmental factors (including number of medications) associated with changes over time in the severity of delirium symptoms and to explore the interactions between these factors and resident baseline vulnerability. Prospective, observational cohort study. Seven long-term care (LTC) facilities. Two hundred seventy-two LTC residents aged 65 and ...
Deblonde T - - 2013
In the context of increasing concerns regarding sustainable development, healthcare workers must consider practices that are not harmful to the environment. 'Primum non nocere' is of great value for the residues of pharmaceuticals and biocides resulting from medical prescriptions. Stockholm County Council has developed a simple classification system covering both ...
Gabardi Steven - - 2013
Objective-To review the history of risk evaluation and mitigation strategies (REMS) with the mammalian target of rapamycin (mToR) inhibitors, evaluate their required REMS elements, and delineate the reasons for them being released from their REMS requirements.Data Sources and Extraction-Articles were identified through a literature search of MEDLINE and EMBASE (January ...
Homedes Núria - - 2013
To determine the benefits and risks of using Mexican pharmacies by better understanding the sociodemographics and medication needs of pharmacy clients in Ciudad Juárez; and to ascertain the role and expertise of pharmacy clerks and their impact on medication use. Cross-sectional study of a convenience sample of 32 pharmacies in ...
Stanulović Vid V School of PhD Studies, Semmelweis University, Budapest, Hungary. - - 2013
Rechallenge is defined as the readministration of a medication suspected of being a possible cause of an adverse reaction and which has been discontinued as result. It may be unintentional when the appearance of a reaction was initially not attributed to the medication. A rechallenge may be intentional when a ...
Costa Vital Paulino - - 2013
To evaluate the need for artificial tears by glaucoma patients under topical hypotensive treatment and to identify risk factors associated with it. The charts of 175 glaucoma patients under medical treatment and 175 age-matched controls were reviewed. Age, gender, use of artificial tears, number of glaucoma medications used, and duration ...
Borja-Oliveira Caroline Ribeiro de - - 2013
In this essay, based on documental analysis, the limitations associated with the use of pill organizers and cutters are discussed and analyzed as a matter of public health. The use of the organizers for storing and carrying tablets and capsules exposes these medications to environmental factors from which their original ...
Zakai N A - - 2013
BACKGROUND: We sought to define the risk factors present at admission for VTE in medical inpatients and develop a risk model for clinical use. METHODS: Between January 2002 and June 2009, 299 cases of hospital-acquired VTE on medical services were frequency matched to 601 controls. Records were abstracted using a ...
Mahan Charles E - - 2013
Background: Hospitalized medically ill patients receiving antithrombotic medications experience increased risk of bleeding. We examined antithrombotic use, bleeding rates, and associated risk factors at 30 days post discharge. Methods: This retrospective database analysis included nonsurgical patients aged ≥40 years hospitalized for ≥2 days during 2005 to 2009. Previously cited, validated ...
Shin Youn Ho - - 2013
Objective. The National Asthma Education and Prevention Program/Expert Panel Report (NAEPP/EPR)-3 Guidelines for asthma treatment categorize asthma severity based on impairment and risks and on medications administered. The objective of this study was to determine whether impulse oscillometry system (IOS) measures in preschool children are consistent with asthma severity as ...
Herzig Shoshana J SJ Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA. - - 2013
It is unknown whether there exist certain subsets of patients outside of the intensive care unit in whom the risk of nosocomial gastrointestinal bleeding is high enough that prophylactic use of acid-suppressive medication may be warranted. To identify risk factors for nosocomial gastrointestinal bleeding in a cohort of non-critically ill ...
Boskovic Jelena - - 2013
Aims: The aims of this study was to determine adherence to chronic disease medication measured by self-reported questionnaire. Methods: The survey was conducted at 106 Zagreb pharmacies, and the questionnaire was filled out by the study subjects. Results: A total 1,357 diagnoses were reported by survey respondents (i.e., an average ...
Gören Jessica L - - 2013
Over the past two decades there has been a large increase in the number of patients prescribed psychotropic medications. Many of these agents are associated with QTc prolongation which is considered a marker for increased risk of sudden cardiac death due to malignant arrhythmias such as Torsades de pointes (TdP). ...
Beach Scott R - - 2013
Prolongation of the corrected QT (QTc) interval is a key issue for patients who receive psychotropic medications. Such patients may have baseline clinical risk factors for QTc prolongation, and many psychotropic medications may further prolong this interval. This has great clinical relevance, as QTc prolongation is linked with dangerous arrhythmias, ...
Deleris Léa A - - 2013
Risk modeling in healthcare is both ubiquitous and in its infancy. On the one hand, a significant proportion of medical research focuses on determining the factors that influence the incidence, severity and treatment of diseases, which is a form of risk identification. Those studies typically investigate the micro-level of risk ...
Joffres Michel - - 2013
The most recent Canadian population-level data on lipid levels are from 1992. This study presents current estimates of Canadians with dyslipidemia, the proportion aware of their condition, and the proportion being treated and below target values. The Canadian Health Measures Survey (2007-2009) assessed the prevalence, awareness and treatment of dyslipidemia. ...
Silva Ana Elisa Bauer de Camargo AE Faculdade de Enfermagem, Universidade Federal de Goiás, Brazil. - - 2013
The objective of this study was to analyze the potential risks involved in the administration process of intravenous anti-infective medication at a medical clinic, using the Failure Mode and Effect Analysis. This exploratory study was conducted at the medical clinic of a hospital in the State of Goiás. For data ...
Silva Anjana A Department of Parasitology, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Anuradhapura 50008, Sri Lanka. - - 2013
This correspondence argues that the dangerousness of a venomous snake species is not solely determined by the venom characteristics or the lethality of the snake, and recognizes that medical importance comprises a key variable as well. The medical importance of a snake is determined by several factors - including frequency ...
Ahlbrandt Janko - - 2013
The best way to ensure patient safety is to eliminate errors. To avoid errors and resulting harm from medical devices, there are rules and laws in Germany to ensure a certain quality and process [1,2]. This does not cover scenarios where devices are connected to a data network, forming a ...
Clark Eloise - - 2013
Extravasation of medications during peripheral intravenous (PIV) therapy can result in harm to pediatric patients. These medications have physical and/or biologic factors that cause tissue damage. To assist in clinical decisions when using these infusates, an evidence-based table of medications stratified by their relative risk of causing harm if extravasated ...
Wiliński Jerzy - - 2013
The execution of the dosing regimen in Polish primary health care is unknown. The aim of the study was to appraise the medication adherence in patients with hypertension of various cardiovascular risk. A prospective interviewer questionnaire-based study included 1,467 consecutive patients with arterial hypertension with the pharmacotherapy containing ramipril in ...
Dow Jamie J Société de l'assurance automobile du - - 2013
Using a databank that combines comprehensive medical data with the driving records of 96% of the drivers in Quebec, odds ratios were calculated for crash risk involving death or serious injury according to the diagnosis of medical conditions traditionally associated with increased crash risk. Results were controlled for age, sex, ...
Li Wei - - 2013
An investigation of safety issues regarding information on contraindications related to cross allergy was conducted to promote clinical awareness and prevent medical errors in a 2200-bed tertiary care teaching hospital. Prescribing information on contraindications concerning cross allergy was collected from an information system and package inserts. Data mining and descriptive ...
Kawakami Aki - - 2012
BACKGROUND: Thirty to forty-five percent of ulcerative colitis (UC) patients show non-adherence to aminosalicylates, and non-adherence has been reported to increase the risk of clinical relapse. Because Japan differs from Western countries in terms of health care and drugs administered, adherence to aminosalicylates in Japan may differ from that elsewhere. ...
Jyun-You Liou - - 2012
To determine whether diabetes control is less optimal in Taiwanese aborigines and identify the risk factors associated with poor glycaemic control. Cross-sectional analysis of data from Taiwan Diabetes Shared Care Program A rural hospital in central Taiwan. Patients enrolled in Diabetes Shared Care Program in 2010 were surveyed. The average ...
Socol Michael L - - 2012
Do obstetricians as a profession risk losing credibility as cesarean section rates continue to rise to once unimaginable levels? Physician practice style and fear of litigation have contributed to the escalation in abdominal delivery but so have societal expectations and patient perspectives. At the same time, some patients are so ...
Zhang Juan - - 2012
OBJECTIVE: To estimate the total economic burden of physical inactivity in China. METHOD: The costs of physical inactivity combine the medical and non-medical costs of five major Non Communicable Diseases (NCDs) associated with inactivity. The national data from the Chinese Behavioral Risk Factors Surveillance Surveys (2007) and the National Health ...
Martinez-Raga Jose - - 2012
Attention-deficit hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder characterized by persistent symptoms of inattention, hyperactivity and/or impulsivity. The proportion of patients diagnosed with ADHD receiving pharmacological treatments has increased enormously in recent years. Despite the well established efficacy and the good safety and tolerability profile, there is concern about ...
Stacey K - - 2012
Previous studies suggested medical schools were failing to provide sufficient support for students undertaking electives in areas with high HIV prevalence and despite updated Department of Health (DoH) guidelines, not all were advising post exposure prophylaxis (PEP) starter packs where appropriate. This study assessed whether there has been improvement in ...
Miao Zhongrong - - 2012
BACKGROUND AND PURPOSE: To investigate the efficacy and safety of percutaneous transluminal angioplasty and stenting (PTAS) for symptomatic middle cerebral artery stenosis compared with standard medical treatment in a low-risk Chinese population. METHODS: A prospective, randomized, controlled, single-center clinical trial was conducted comparing PTAS with medical treatment for symptomatic middle ...
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