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Loukas Marios M Department of Anatomical Sciences, School of Medicine, St. George's University, Grenada, West Indies; Department of Anatomy, Varmia and Mazuria Medical School, Olsztyn, - - 2014
Étienne-Arthur Louis Fallot (1850-1911) is one of the most significant medical figures of the 19th century with an eponymous congenital cardiac malformation. His initial account of the four anatomical features making up his tetralogy proved remarkably significant in the progression of clinical descriptions of the lesions producing cyanotic congenital cardiac ...
Ko Wen-Tsai WT Chang Gung University, Tao-Yuan, Taiwan, - - 2014
RFID technology is increasingly used in applications that require tracking, identification, and authentication. It attaches RFID-readable tags to objects for identification and execution of specific RFID-enabled applications. Recently, research has focused on the use of grouping-proofs for preserving privacy in RFID applications, wherein a proof of two or more tags ...
- - 2014
This award-winning app from Swedish medical technology company Diabetes Tools is available in English and Swedish. It holds the CE mark, signalling compliance with European Union medical device regulations.
Volpatti Lisa R LR Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, - - 2014
Microfluidic devices offer automation and high-throughput screening, and operate at low volumes of consumables. Although microfluidics has the potential to reduce turnaround times and costs for analytical devices, particularly in medical, veterinary, and environmental sciences, this enabling technology has had limited diffusion into consumer products. This article analyzes the microfluidics ...
Hogan Andrew J AJ Department of History, Humanities Center 225, Creighton University, 2500 California Plaza, Omaha, NE 68178, - - 2014
This paper explores evolving conceptions and depictions of the human genome among human and medical geneticists during the postwar period. Historians of science and medicine have shown significant interest in the use of informational approaches in postwar genetics, which treat the genome as an expansive digital data set composed of ...
Earp Brian D BD Uehiro Centre for Practical Ethics,University of - - 2014
Pharmaceuticals or other emerging technologies could be used to enhance (or diminish) feelings of lust, attraction, and attachment in adult romantic partnerships. While such interventions could conceivably be used to promote individual (and couple) well-being, their widespread development and/or adoption might lead to "medicalization" of human love and heartache-for some, ...
Gaglani Shiv M SM Mr. Gaglani is a third-year medical student, Johns Hopkins University School of Medicine, Baltimore, Maryland. Dr. Topol is director, Translational Science Institute, Scripps Research Institute, and chief academic officer, Scripps Health, San Diego, - - 2014
Mobile health (mHealth) technologies have experienced a recent surge in attention because of their potential to transform the delivery of health care. This enthusiasm is partly due to the near ubiquity of smartphones and tablets among clinicians, as well as to the stream of mobile medical apps and devices being ...
Hosseinidoust Zeinab Z Department of Chemical Engineering, McGill University, Montreal, QC, Canada H3A - - 2014
Bacteriophage-functionalized bioactive surfaces are functional materials that can be used as antimicrobial surfaces in medical applications (e.g., indwelling medical devices or wound dressings) or as biosensors for bacterial capture and detection. Despite offering immense potential, designing efficient phage-functionalized bioactive surfaces is hampered by a number of challenges. This review offers ...
Seeger Christian - - 2014
An ever-growing range of wireless sensors for medical monitoring has shown that there is significant interest in monitoring patients in their everyday surroundings. It however remains a challenge to merge information from several wireless sensors and applications are commonly built from scratch. This paper presents a middleware targeted for medical ...
Franz Alfred M - - 2014
Object tracking is a key enabling technology in the context of computer-assisted medical interventions. Allowing the continuous localization of medical instruments and patient anatomy, it is a prerequisite for providing instrument guidance to subsurface anatomical structures. The only widely used technique that enables real-time tracking of small objects without lineof- ...
Baillie Jonathan - - 2014
Early 2013 saw Brandon Medical, which designs and manufactures equipment ranging from operating theatre lighting to medical AV and control systems, celebrate '20 years of innovation and growth', with a move to a new pounds 2 million, 50,000 ft2 headquarters in Morley near Leeds, twice the size of its former ...
Kingkaew Pritaporn - - 2014
While many of the principles that guide the economic evaluation of medical devices are somewhat similar to those that guide the evaluation of other health technologies, most outline a methodology that focuses on pharmaceutical products rather providing specific guidance for medical devices. Given that medical devices use a wide range ...
Bowton Erica E Institute for Clinical and Translational Research, School of Medicine, Vanderbilt University, Nashville, TN 37232, - - 2014
The use of electronic medical record data linked to biological specimens in health care settings is expected to enable cost-effective and rapid genomic analyses. Here, we present a model that highlights potential advantages for genomic discovery and describe the operational infrastructure that facilitated multiple simultaneous discovery efforts.
Vasarhelyi Barna B Department of Laboratory Medicine, MTA-SE, Pediatrics and Nephrology Research Group, Semmelweis University Budapest, - - 2014
In this world, nothing is certain but death and taxes, Benjamin Franklin declares in his bon mot. For the medical staff the major challenge is to delay or at least predict the time when the unavoidable fatal outcome will occur in an individual. During thousands of years generations used different ...
Issa Naiem T NT Department of Oncology, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC - - 2014
Advancements in genomics and personalized medicine not only effect healthcare delivery from patient and provider standpoints, but also reshape biomedical discovery. We are in the era of the '-omics', wherein an individual's genome, transcriptome, proteome and metabolome can be scrutinized to the finest resolution to paint a personalized biochemical fingerprint ...
Klymiuk Ingeborg I Core Facility Molecular Biology, Center for Medical Research, Medical University of Graz, Graz, - - 2014
Christoph Steininger and colleagues explore how multiple infectious, autoimmune, metabolic, and neoplastic diseases have been associated with changes in the intestinal microbiome, although a cause-effect relationship is often difficult to establish. Integration of metagenomics into clinical medicine is a challenge, and the authors highlight clinical approaches that are of high ...
Jahrling Peter B PB Integrated Research Facility at Fort Detrick, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA; Emerging Viral Pathogens Section, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, - - 2014
Scientists at the National Institute of Allergy and Infectious Diseases Integrated Research Facility at Fort Detrick, Frederick, Maryland coordinate and facilitate preclinical research on infectious diseases to develop medical countermeasures for high consequence pathogens. This facility is unique in that it is the only maximum containment laboratory in the world ...
Willits Iain I Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Freeman Road, Newcastle upon Tyne, NE7 7DN, - - 2014
The Microlife(®) 'WatchBP Home A' oscillometric blood pressure monitor detects irregular pulse, suggestive of atrial fibrillation (AF). Early detection of AF can prevent thromboembolic stroke via anticoagulation therapy. The device was considered by the Medical Technologies Evaluation Programme of the UK National Institute for Health and Care Excellence (NICE). The ...
Branescu I I Faculty of Automatic Control and Computers, Polytechnic University of - - 2014
The paper discusses the methods to apply OLAP techniques for multidimensional databases that leverage the existing, performance-enhancing technique, known as practical pre-aggregation, by making this technique relevant to a much wider range of medical applications, as a logistic support to the data warehousing techniques. The transformations have practically low computational ...
Demmer Laurie A LA Deparment of Pediatrics, Carolinas Medical Center, Charlotte, NC 28232; email: - - 2014
Genomic medicine is a relatively new concept that involves using individual patients' genomic results in their clinical care. Genetic technology has advanced swiftly over the past decade, and most providers have been left behind without an understanding of this complex field. To realize its full potential, genomic medicine must be ...
Carruth Lauren L Global Health & Health Policy Program, Woodrow Wilson School of Public & International Affairs, Princeton University, Princeton, NJ 08540, USA. Electronic address: - - 2014
This paper details how exposure to new clinics, diagnostic technologies, and pharmaceuticals during humanitarian relief operations in the Somali Region of Ethiopia shaped local pluralistic health systems and altered the ways in which residents subsequently conceived of and treated illness and disease. Despite rising demand for pharmaceuticals and diagnostic technologies ...
Leung Alexander A AA From the *Brigham and Women's Hospital, Boston, Massachusetts; †Texas Medical Institute of Technology, Austin, Texas; and ‡Boston Medical Center, Boston, - - 2014
Safety advocates have identified barcode verification technology as an important tool to improve health-care practices. We evaluated the evidence for the role of barcode technology in improving a wide range of medication safety outcomes across a broad range of settings. Important implementation issues were highlighted to guide standards for the ...
Gioli-Pereira Luciana - - 2014
Studies adopting electronic medical records and genomic information are becoming widespread. Through this new modality in research, it is possible to study how genetic variants influence susceptibility towards chronic conditions and can improve patient care.Our aim is to develop a biobank with 2,000 heart failure patients treated in a tertiary ...
Wink Michael M Heidelberg University, Institute of Pharmacy and Molecular Biotechnology, Heidelberg, Germany. - - 2014
This issue of Biotechnology Journal is a regular issue edited by Prof. Michael Wink. The issue covers all the major focus areas of the journal, including medical biotechnology, synthetic biology, and novel biotechnological methods.
Kapoor Shalini S Assistant Professor, Department of Periodontics and Implantology, SGT Dental College Gurgaon, Haryana India - - 2014
Haptics, or touchsense haptic technology is a major breakthrough in medical and dental interventions. Haptic perception is the process of recognizing objects through touch. Haptic sensations are created by actuators or motors which generate vibrations to the users and are controlled by embedded software which is integrated into the device. ...
Tsao Nicole W NW , BSc, MSc(Pharm), is with the Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia. She was one of the two co-leads on this - - 2014
Technologies have been developed over the past 20 years to automate the stages of drug distribution in hospitals, including ordering, dispensing, delivery, and administration of medications, in attempts to decrease medication error rates. Decentralized automated dispensing devices (ADDs) represent one such technology that is being adopted by hospitals across Canada, ...
Iv Edward C Oldfield EC Edward C Oldfield IV, Edward C Oldfield III, David A Johnson, Division of Gastroenterology, Division of Infectious Disease, Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23508, United - - 2014
Clostridium difficile infection (CDI) presents a rapidly evolving challenge in the battle against hospital-acquired infections. Recent advances in CDI diagnosis and management include rapid changes in diagnostic approach with the introduction of newer tests, such as detection of glutamate dehydrogenase in stool and polymerase chain reaction to detect the gene ...
Kaiser Stephanie S Institute of History, Theory and Ethics in Medicine, Medical School, RWTH Aachen - - 2014
Objectives: This study explores the awareness and the degree of acceptance of the idea of the medical technology cryonics-the freezing of a corpse to revive it in the future-among German citizens. Methods: Data were collected on the basis of a representatively weighted online survey of 1,000 people aged between 16 ...
Foley Ronan R Department of Geography, National University of Ireland Maynooth, Maynooth, County Kildare, Ireland. Electronic address: - - 2014
The invention of a new form of hot-air bath in Blarney, Ireland in 1856, variously known in its lifetime as the Roman-Irish or Turkish Bath, acted as the starting point for a the production of a globalised therapeutic landscape. Tracking the diffusion of the Roman-Irish bath template from its local ...
Pereira Jorge J CQM - Centro de Química da Madeira, Universidade da Madeira, Campus Universitário da Penteada, 9000-390, Funchal, - - 2014
The human population continues to grow exponentially in the fast developing and most populated countries, whereas in Western Europe it is getting older and older each year. This inevitably raises the demand for better and more efficient medical services without increasing the economic burden in the same proportion. To meet ...
Cassidy Lindsey L Department of Anatomical Sciences, School of Medicine, St. George's University, Grenada, West - - 2014
Friedrich Trendelenburg's name is widely known today because it is associated with the Trendelenburg position. However, Trendelenburg made many other valuable contributions to the field of medicine, including a test, a gait, and a sign. A historical review of his life helps to elucidate the factors that contributed to his ...
Yetisen Ali Kemal AK Department of Chemical Engineering and Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QT, UK. - - 2014
The rapidly expanding number of mobile medical applications have the potential to transform the patient-healthcare provider relationship by improving the turnaround time and reducing costs. In September 2013, the U.S. Food and Drug Administration (FDA) issued guidance to regulate these applications and protect consumers by minimising the risks associated with ...
Gong Max M MM Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, Canada M5S 3G8. - - 2014
We present a low cost, simple and integrated device for medical diagnostics in low-resource settings called the lab-in-a-pen. Finger pricking, and sample collection and processing, are integrated with commercially available paper-based assays in a pen format. This approach ensures safety (i.e. biological sample and sharps containment) and can be used ...
Sweet Kevin K Division of Human Genetics, Ohio State University Wexner Medical Center, Columbus, OH 43420, USA ; Center for Personalized Health Care, Ohio State University Wexner Medical Center, Columbus, OH 43420, - - 2014
We describe the development and implementation of a randomized controlled trial to investigate the impact of genomic counseling on a cohort of patients with heart failure (HF) or hypertension (HTN), managed at a large academic medical center, the Ohio State University Wexner Medical Center (OSUWMC). Our study is built upon ...
Bruley Duane F DF Synthesizer, Inc., 2773 Westminster Road, Ellicott City, MD, 21043, USA, - - 2014
The founding of ISOTT was based upon the blending of Medical and Engineering sciences. This occurrence is portrayed by the Shamattawa, the joining of the Chippewa and Flambeau rivers. Beginning with Carl Scheele's discovery of oxygen, the medical sciences advanced the knowledge of its importance to physiological phenomena. Meanwhile, engineering ...
Connolly John J JJ The Center for Applied Genomics, Children's Hospital of Philadelphia Philadelphia, PA, - - 2014
The goal of this paper is to review recent research on copy number variations (CNVs) and their association with complex and rare diseases. In the latter part of this paper, we focus on how large biorepositories such as the electronic medical record and genomics (eMERGE) consortium may be best leveraged ...
Al Qahtani Fahd F Radiology Department, Faculty of Medicine, Al-Baha University, Al-Baha, Saudi - - 2014
Fulfilling the goal of integrating radiology into undergraduate medical curricula is a real challenge due to the enduring faith assuming that traditional medical disciplines are worthy of consuming the available study time. In this manner, radiology is addressed occasionally and with relevance to these traditional disciplines. In Al-Baha University Faculty ...
Bergsland Jacob J The Intervention Centre, Oslo University Hospital, Institute of Clinical Medicine, University of Oslo, Oslo, - - 2014
The US Food and Drug Administration (FDA) has defined a medical device as a health care product that does not achieve it's purpose by chemical action or by being metabolized. This means that a vast number of products are considered medical devices. Such devices play an essential role in the ...
Bubalo Joseph J 1Department of Pharmacy Services, Oregon Health & Science University, OR, - - 2013
PurposeMedical errors, in particular medication errors, continue to be a troublesome factor in the delivery of safe and effective patient care. Antineoplastic agents represent a group of medications highly susceptible to medication errors due to their complex regimens and narrow therapeutic indices. As the majority of these medication errors are ...
Evans Barbara J BJ Center for Biotechnology & Law, University of Houston Law Center, Houston, Texas, - - 2013
The Supreme Court's recent decision in Association for Molecular Pathology v. Myriad Genetics portrays the human genome as a product of nature. This frames medical genetics as an extractive industry that mines a natural resource to produce valuable goods and services. Natural resource law offers insights into problems medical geneticists ...
Finocchiaro Castro Massimo M Mediterranean University of Reggio Calabria, Department of Law and Economics, Via Tommaso Campanella, 38/A, 89125 Reggio Calabria, - - 2013
The aim of this study was to investigate how the differences across the regional reimbursement mechanisms and in particular the use of the DRGs impact on the level in the high technology equipment diffusion. Based on hospital sector data at a regional level we build up indicators to measure the ...
Makiuchi Takashi - - 2013
The mitochondria have arisen as a consequence of endosymbiosis of an ancestral α-proteobacterium with a methane-producing archae. The main function of the canonical aerobic mitochondria include ATP generation via oxidative phosphorylation, heme and phospholipid synthesis, calcium homeostasis, programmed cell death, and the formation of iron-sulfur clusters. Under oxygen-restricted conditions, the ...
Elkin P L - - 2013
Introduction: This article is part of a For-Discussion-Section of Methods of Information in Medicine on "Biomedical Informatics: We are what we publish". It is introduced by an editorial and followed by a commentary paper with invited comments. In subsequent issues the discussion may continue through letters to the editor. Objective: ...
Chen Yang - - 2013
By the end of 2012, there were 272 modern, high-standard, centralized medical waste disposal facilities operating in various cities in China. Among these facilities nearly 50% are non-incineration treatment facilities, including the technologies of high temperature steam, chemical disinfection and microwave. Each of the non-incineration technologies has its advantages and ...
Carnevali Lise - - 2013
Medication-related harm can be detected using the adverse drug event (ADE) trigger tool and the medication module of the Global Trigger Tool (GTT) developed by the Institute for Healthcare Improvement (IHI). In recent years, there has been some controversy on the performance of this method. In addition, there are limited ...
Sim┼ček Enver E Division of Pediatric Endocrinology, Department of Pediatrics University College London, London, United Kingdom. - - 2013
Congenital hyperinsulinism (CHI) is a common cause of hypoglycemia in infants. We report three cases of CHI with differing clinical, biochemical, and molecular genetic spectra. One patient was unresponsive to medical treatment and died after subtotal pancreatectomy because of complications due to the surgery. Two patients have been followed successfully ...
Wang Xiaoliang - - 2013
The severe challenges of the skyrocketing healthcare expenditure and the fast aging population highlight the needs for innovative solutions supporting more accurate, affordable, flexible, and personalized medical diagnosis and treatment. Recent advances of mobile technologies have made mobile devices a promising tool to manage patients' own health status through services ...
Opitz John M - - 2013
In their ontogeny and phylogeny all living beings are historical entities. The revolution in biology of the 18th and 19th centuries that did away with the scala naturae according to which we humans, the acme of creation, "made a little lower than the angels," also led to the gradual realization ...
Nelson Danielle - - 2013
The recent technological advance of digital high resolution imaging has allowed the field of pathology and medical laboratory science to undergo a dramatic transformation with the incorporation of virtual microscopy as a simulation-based educational and diagnostic tool. This transformation has correlated with an overall increase in the use of simulation ...
Sutter Raoul - - 2013
The term encephalopathy encompasses a wide variety of syndromes caused by a large number of different toxic, metabolic, and degenerative derangements. Despite advances in intensive medical care and new diagnostic procedures, encephalopathy remains a frequent and underrecognized critical medical condition with high morbidity and mortality. Electroencephalography (EEG) enables rapid bedside ...
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