BACKGROUND: Prescription medication use increases with age. Seniors face an increased risk of adverse drug reactions from medications, partly because the kidneys and liver can lose functional ability with increasing age, resulting in the need for changes in dosage. OBJECTIVE: To use population survey data to understand the extent and ...

Imatinib mesylate (STI-571, Gleevec(®)), a tyrosine kinase inhibitor, is a first-line medication for treating chronic myeloid leukemia (CML). Clinical studies revealed very good hematological responses without significant side effects. However, imatinib may lead to mucosal pigmentation. Three patients, two males aged 64 and 53 and one female aged 29 presented ...

Using two-period panel data from the Nippon Life Insurance Research Institute, this paper tests the hypothesis that an increase in the self-pay ratio of medical expenditures associated with the Japanese health insurance reforms of April 2003 reduced household medical expenditures. We find that the increase in the self-pay ratio had ...

ABSTRACT: BACKGROUND: For adolescents with a diagnosis of lifelong chronic illness, mastery of self-management skills is a critical component of the transition to adult care. This study aims to examine self-reported medication adherence and self-care skills among adolescents with chronic rheumatic disease. METHODS: Cross-sectional survey of 52 adolescent patients in ...

This study aimed to analyse medication errors committed by health care professionals leading to toxicological consultations at the Czech Toxicological Information Centre (TIC), and to identify the categories of special concern for further interventions of health care quality experts. From the TIC database, 44,344 calls concerning drug application were studied ...

SUMMARYThe objective of the present study was to evaluate the anticoccidial effect of different concentrations of the herbal complex of 4 plants (leaves of Azadirachta indica and Nicotiana tabacum, flowers of Calotropis procera and seeds of Trachyspermum ammi) in broiler chickens in comparison with amprolium anticoccidial. Three concentrations (2 g, ...

This paper aims to determine the prevalence, patterns, and demographic and diagnostic correlates of psychotropic medication use in a sample of youth in one state's post-adjudicatory secure facilities. The health records database of the facilities was the source of linked demographic, diagnostic and pharmacy information for the 1-year period ending ...

We investigated the effect of text message reminders about medication administration. The study concerned children with cystic fibrosis. We provided 20 children (aged 5-12 years) with pagers that they could customize. For the first two weeks, we sent friendly text messages (non-reminder content) near medication times to acquaint them with ...

Recently, the Israel National Bioethics Council (INBC) issued recommendations permitting egg freezing to prevent both disease- and age-related fertility decline. The INBC report forms the basis of Israel's new policy, being one of the first countries to regulate and authorise egg freezing for what it considers to be non-medical (ie, ...

Brown Medical School developed a comprehensive curriculum in which enriched aging content increased from 22 to 80 hours in preclerkship courses and was also added for clerkships, residencies, and nongeriatrician physicians. Innovative evaluation strategies are also described. Highlights include "treasure hunts" in the anatomy laboratory, a Scholarly Concentration in Aging, ...

Emergency medicine (EM) educators have published several curricular guides designed for medical student rotations and experiences. These guides primarily provided brief overviews of opportunities to incorporate EM into all 4 years of the medical student curriculum, with one specific to the fourth year. However, there are no published guidelines specific ...

OBJECTIVES: To examine the relationship between self-perceptions of aging and acute medical events in chronically institutionalized middle-aged and older persons with schizophrenia. METHODS: Participants were 83 persons with schizophrenia (30% women; mean age = 58.48, SD = 8.14) residing in a long-stay care home, who were without organic mental disorders, mental retardation, serious audiovisual ...

Florida Medicaid claims data were used to assess antipsychotic medication use among children after therapeutic out-of-home mental health treatment. Fifty percent of youth received antipsychotics after the treatment episode, but differences exist across age, gender, and racial groups. Utilization was higher among males and youth ages 6-12, while blacks were ...

This research explores the social factors influencing hospital physicians' initial adoption of duloxetine hydrochloride, with a focus on colleague interactions. The study analyzes archival data compiled by the National Health Insurance Research Database of Taiwan to examine how the prescribing decisions made by psychiatrists' colleagues influence the likelihood of the ...

Throughout the history of medical science, the sourcing, storage, and management of cadavers for the study of gross anatomy have been problematic issues. As presented in this report, a study of these issues was conducted in the departments of anatomy of medical schools in Nigeria. To establish the extent and ...

Irritable bowel syndrome (IBS) is prevalent in general population. This study investigates the prevalence of IBS in medical college students in Korea as well as the influence of dietary habits and nutritional intake on IBS. This study is a cross-sectional study of 319 students (239 males and 80 females, age ...

Yoga has been shown to have many short-term health benefits, but little is known about the extent to which these benefits accrue over a long time frame or with frequent practice. The purpose of this study was to examine the extent to which body mass index (BMI) and medication use ...

In December 2009, the Israel National Bioethics Council (INBC) issued recommendations permitting egg freezing to prevent both disease- and age-related fertility decline. The INBC report forms the basis of Israel's new policy regarding egg freezing. This article analyzes the medical section of the INBC's recommendations, comparing it with guidelines formulated ...

PURPOSE: To compare Canadian medical graduates (CMGs) and international medical graduates (IMGs) who completed postgraduate medical education in Canada from 1989 to 2007 by age, gender, specialty, and practice characteristics. METHOD: Data on all CMGs and IMGs who completed residencies or fellowships training in Canada from 1989 to 2007 were ...

Blood pressure-lowering (BPL) and lipid-lowering (LL) medications together reduce estimated absolute five-year cardiovascular disease (CVD) risk by >40%. International studies indicate that the proportion of people with CVD receiving pharmacotherapy increases with advancing age. To compare BPL and LL medications, by sociodemographic characteristics, for patients with known CVD in primary ...

The aim of this study was to analyse the types of and rationale for the clinical recommendations made by the pharmacist in a rural aged care facility to improve patient safety. The classes of drugs associated with the pharmacist's recommendations were also identified. A related aim was to determine their ...

A national internet survey was conducted between March and April 2009 among 27,302 US participants in the Harris Interactive Chronic Illness Panel. Respondents reported behaviors related to cost-related medication non-adherence (CRN) and the impacts of medication costs on other aspects of their daily lives. Among respondents aged 40-64 and looking ...

We studied the prevalence of polypharmacy in attenders aged 75 years and over to an emergency department (ED) in North London over a period of 1 month. We identified 467 patients in this age group. Analysis of medications being prescribed revealed at least 82 patients on medication with the potential ...

In medical education, it is important for medical students to develop their ethics to respect patients' rights. Some physicians might make light of patients' rights, because the increased awareness of such rights might make it more difficult for them to conduct medical practice. In the present study, predictors significantly associated ...

Objective People who spend a longer time walking have lower demands for medical care. However, in view of their longer life expectancy, it is unclear whether their lifetime medical expenditure increases or decreases. The present study examined the association between time spent walking, life expectancy and lifetime medical expenditure. Method ...

A probable interaction between warfarin and honeybee-collected pollen is reported. A 71-year-old Caucasian man arrived at an anticoagulation clinic for routine warfarin monitoring with an International Normalized Ratio (INR) value of 7.1 (therapeutic range, 2.0-3.0). His medical history included atrial flutter, hypertension, hyperlipidemia, diabetes mellitus, erectile dysfunction, obesity, and hypothyroidism. ...

Because of the risk of suffering a stroke or heart attack, some athletes and their medical supervisors admitted having used anticoagulants (e.g. acetylsalicylic acid) in combination with doping with recombinant erythropoietins (rhEPO). Heparin is one of the oldest and cheapest anticoagulants. The anticoagulative effect of heparin is a result of ...

P values are widely used in the medical literature but many authors, reviewers, and readers are unfamiliar with a valid definition of a P value, let alone how to interpret one correctly. Popular explanations such as "the probability that study results are due to chance" are wrong in a variety ...

Unplanned (unexpected) transfers to the intensive care unit (ICU) are typically preceded by physiologic instability. However, trends toward instability may be subtle and not accurately reflected by changes in vital signs. The shock index (SI) (heart rate/systolic blood pressure as an indicator of left ventricular function, reference value of 0.54) ...

Whereas numerous studies document the effects of dopamine medication and deep brain stimulation on motor function in patients with Parkinson's disease, few have investigated deep brain stimulation-induced changes in sensory functions. In this study of 13 patients with Parkinson's disease, we tested the effects of deep brain stimulation on the ...

New values and practices associated with medical professionalism have created an increased interest in the concept. In the United Kingdom, it is a current concern in medical education and in the development of doctor appraisal and revalidation. To investigate how final year medical students experience and interpret new values of ...

The ability to auscultate during air medical transport is compromised by high ambient noise levels. The aim of this study was to assess the capabilities of a traditional and an amplified stethoscope (which is expected to reduce background and ambient noise) to assess heart and breath sounds during medical transport ...

Many of the characteristics of typical medical waste ash can be found by using ash leaching experiments. The present study investigated the characteristics of fly ash derived from incineration of medical waste in China. The particle diameter of the fly ash was in the range 154-900 microm. Elemental analyses of ...

Radioxenon isotopes play a major role in confirming whether or not an underground explosion was nuclear in nature. It is then of key importance to understand the sources of environmental radioxenon to be able to distinguish civil sources from those of a nuclear explosion. Based on several years of measurements, ...

OBJECTIVES: Determining post-tonsillectomy haemorrhage (PTH) risk factors is crucial for preventing it. The aim of the study was to analyse results of coagulation tests and preoperative family and medical history of coagulation disorders in order to establish if they have predictive value for PTH. METHODS: In 222 patients aged 15-60 ...

In her 2003 article in the British Medical Journal, Ruth Macklin provocatively declared dignity to be a useless concept: either a vague restatement of other more precise values, such as autonomy or respect for persons, or an empty slogan. A recent response to Macklin has challenged this claim. Doris Schroeder ...

Medical students' values represent an understudied area of research in medical education research. No known studies have investigated how medical students' values change over time from matriculation to graduation. Values are thought to remain relatively stable over the life course. However, little research supports this claim. Therefore, we examined the ...

Central elements of the Bologna declaration have been implemented in a huge variety of curricula in humanities, social sciences, natural sciences and engineering sciences at German universities. Overall the results have been nothing less than disastrous. Surprisingly, this seems to be the perfect time for German universities to talk about ...

OBJECTIVE: To examine the types, quantities, and monetary value of drugs which are disposed of by patients of outreach pharmacists, and to describe the role of outreach pharmacists in promoting the safe disposal of drug waste and reducing medication cost. SETTING: An Outreach Medication Review service at a major public ...

BACKGROUND: Over the years, business valuation techniques have been widely used to appraise the financial worth of medical practices. However, it has been argued that medical practices are one of the most complex and difficult types of business enterprises to value. PURPOSE: The purpose of the current study is to ...

Markets for medical travel have grown immensely in the past few years. They have attracted the attention not only of healthcare consumers, providers, and payors but also of scholars from various disciplines. This editorial demonstrates some of the ways that anthropology can contribute to current efforts to better understand medical ...

Hospital librarians routinely develop relationships with users and vendors as well as operate as valuable members of multidisciplinary teams, but rarely do they report working with executive level partners on a continuing basis. This can result in a lower perception of a librarian's value to the organization due to the ...

Prospective population studies of incident heart failure (HF) are often limited by difficulties in assembling HF-free cohorts. In this study, public-use copies of the Cardiovascular Health Study (CHS) data sets were used to determine the sensitivity, specificity, and positive and negative predictive values of orthopnea and paroxysmal nocturnal dyspnea (PND), ...

Cylinders of medical grade silicone elastomers, (29 mm in diameter and 13 mm thick), immersed in physiological saline solution at 37 degrees C, were investigated by dynamic mechanical analysis (DMA). A sinusoidal cyclic compression of 40 +/- 5 N was applied over a frequency range, f, of 0.02-100 Hz. Values ...

BACKGROUND: An effort to share our many years of clinical experience. Objective: To predict the effectiveness of medication in advanced phases of dementia in the light of pharmaceutical economics and to find the most suitable alternative treatments. METHODS: Use of 3 commonly available geriatric tests Mini-Mental State Examination (MMSE), Activity ...

Commercial support of continuing medical education/continuing professional development (CME/CPD) is a fact of life currently, though under attack from several sources. Does it have a positive or negative value to industry, to physicians, to society, and to CME professionals? There is sufficient evidence to support positive value to industry. There ...

Uranium (238U) and thorium (232Th) concentrations as well as radon (222Rn) and thoron (220Rn) alpha activities per unit volume have been measured inside 18 medical drugs (4 liquid and 14 solid materials), widely prescribed by doctors to the Moroccan adult patients, by using CR-39 and LR-115 type II solid state ...

ABSTRACT : Problems associated with medication use and the consequent effects on genome-wide association analyses were explored using the Genetic Analysis Workshop 16 Problem 3 data. Lipid phenotypes were simulated in the Framingham Heart Study using several measured variables including causal genes (based on a 500 k SNP panel), smoking, ...

A number of authors have shown how medical decisions are influenced by social values; others have minimized the putative influence of values and have argued that medical decisions are predominantly constrained by the organization of medical work. Based on fieldwork in France and the USA observing pre-hospital resuscitations, we seek ...

The present article seeks to explain varying levels of assertiveness in interpersonal conflict and negotiations with assertiveness expectancies, idiosyncratic predictions people make about the social and instrumental consequences of assertive behavior. This account complements motivation-based models of assertiveness and competitiveness, suggesting that individuals may possess the same social values (e.g., ...