A peptidomics approach was applied to determine the peptides in the larval central nervous system of the grey flesh fly, Neobellieria bullata. Fractions obtained by high performance liquid chromatography were analysed by MALDI-TOF and ESI-Q-TOF mass spectrometry. This provided biochemical evidence for the presence of 18 neuropeptides, 11 of which ...

The aim of this paper is to evaluate the feasibility of a mission to Mars using the Integrated Propulsion Systems (IPS) which means to couple Nuclear-MPD-ISPU propulsion systems. In particular both mission analysis and propulsion aspects are analyzed together with technological aspects. Identifying possible mission scenarios will lead to the ...

The Internet offers an unprecedented opportunity to construct powerful large-scale medical expert systems (MES). In these systems, a cost-effective medical knowledge acquisition (KA) and management scheme is highly desirable to handle the large quantities of, often conflicting, medical information collected from medical experts in different medical fields and from different ...

Many information systems have failed when deployed into complex health-care settings. We believe that one cause of these failures is the difficulty in systematically accounting for the collaborative and exception-filled nature of medical work. In this methodological review paper, we highlight research from the field of computer-supported cooperative work (CSCW) ...

To enhance medical cooperation between the hospitals and clinics around Osaka local area, the healthcare network system, named Osaka Community Healthcare Information System (OCHIS), was established with support of a supplementary budget from the Japanese government in fiscal year 2002. Although the system has been based on healthcare public key ...

Emergency medical services (EMS) is an organised system designed to transport sick or injured patients to the hospital. Though EMS system configurations can be quite varied in design depending on locale, we provide an overview of EMS as it has evolved and is currently modelled in the US. We outline ...

The Australian Government's medical indemnity package is predicated on the belief that the current crisis is primarily one of insurance. However, an examination of the fault-based tort system illustrates that, irrespective of their insurance status, doctors are profoundly affected by the adversarial process and their response to it is leading ...

The medical profession has always fiercely defended its right to self-regulation on the basis of peer review. However, in New South Wales, Australia, the profession has willingly surrendered these rights in favour of a disciplinary system known as co-regulation or collaborative regulation, under which disciplinary processes are shared with a ...

While it is widely written that advanced clinical information systems can help healthcare organizations reduce adverse medical events and increase patient safety, Alamance Regional Medical Center (ARMC) has proven that it truly does. ARMC chose Eclipsys' Sunrise Clinical Manager for its ability to provide knowledge-based clinical decision support and its ...

The support systems for the Emergency Medical Services (EMS) in the mass gatherings, such as the local marathon or the large international baseball games, had been underdeveloped. The purposes for this study were to develop triage-based EMS Personal Digital Assistant (PDA) support systems for the mass-gatherings and to evaluate users' ...

Capitalizing on existing IT investments, INTEGRIS Health, a 15-hospital system in Oklahoma, is applying business process integration (BPI) methodology and technology to leverage legacy systems and staff resources. The resulting project uses manual (human) and system tasks to compare real-time information across systems to eliminate preventable adverse drug events caused ...

A medical terminological system (TS) is essentially a representation of concepts, attributes and relationships pertaining to medical terms. Although the requirements and structures of TSs have enjoyed some attention in the literature, the actual implementation of TSs consisted so far of ad-hoc approaches starting from scratch. Recently, Protégé has been ...

Medical diagnosis and treatment constitute a network of interrelated processes. The conventional method of medical diagnosis and treatment of diseases involves a state space search of the medical knowledge of diseases and patient history, which could be combinatorially explosive. This paper presents a report on the experimental study of an ...

As neuroprosthetic control systems continue to advance and increase in channel density, there will be a constant need to deliver data at higher bandwidths in and out of the body. Currently, RF telemetry and inductive coupling are the most commonly used methods for transmitting power and electronic data between implants ...

Medical decision support systems will only be accepted by the medical community if properly evaluated. However, little attention has been given in the scientific literature to the topic of how to incorporate evaluation issues into the design of a decision-support system. In this paper, we describe work in developing a ...

The adrenal cortex is regarded as the organ most vulnerable to toxicity within the endocrine system. The production of cortisol, among the many steroidal hormones produced by the cortex, may suffer as a result. In a veterinary clinical practice, household dogs and cats with a wide variety of diseases ranging ...

The aim of this article is to independently implement an indispensable front-end platform in a network-based intelligent home healthcare system. We propose to realize an ARM-cored structure embedded with muClinux system to integrate several kinds of medical measuring modules with our platform. Then we demonstrate the platform work cooperatively with ...

Free-text forms of medical guidelines that are used in medical care are often cumbersome and difficult to memorize. Therefore a system that is able to present guidelines in a user-friendly manner has been designed. Guidelines are at first formalized by means of the popular GLIF3 model. Subsequently, the GLIF3 model ...

A method for controlling unstable periodic orbits (UPOs) that have not been controllable before is presented. The method is based on detecting UPOs that are situated outside the skeleton of a chaotic attractor. The main idea is to exploit flexible parts of the attractor, which under weak external perturbations allow ...

Implementation of CPOE systems in Healthcare Institutions has proven efficient in reducing medication errors but it also induces hidden side-effects on Doctor-Nurse cooperation. We propose a usability engineering approach to this problem. An extensive activity analysis of the medication ordering and administration process was performed in several departments of 3 ...

Medical academic systems are characterized by interplay between accomplishment and process. The term accomplishment refers to fulfillment of the system's original goals, such as education, research and medical care, whereas the term process refers to the culture and structure, which are developed to pursue these goals. A mathematical model is ...

Cardiovascular diseases and, in particular, diseases related to arrhythmias are a problem that affects a significant percentage of the population, being one of the major causes of death in Europe. New advances in the fields of PDAs, mobile phones, wireless communications and vital parameter sensors have permitted the development of ...

Munakata Medical Association Hospital is leading the way with its liaison system for electronic medical records and sharing medical information system in Munakata area clinics. A validity experiment was carried out from December 2001 to Autumn 2003 and over 600 patient joined the examination. 90% of the patients surveyed judged ...

Interoperability standards, if properly applied to medical system design, have the potential to decrease the cost of point-of-care monitoring systems while better matching systems to patient needs. This paper presents a brief editorial overview of future monitoring environments, followed by a short listing of smart-home and wearable-device efforts. This is ...

Endometrial ablation is an excellent alternative to hysterectomy in women with menorrhagia and small intramural fibroids. Preoperative evaluation, which includes office hysteroscopy or saline infusion sonography, is critical to patient management and choice of procedure. A vast array of endometrial ablation technology is available currently that includes balloon therapy, cryosurgery ...

A unique microarray approach has been developed to profile alternative splicing in the cell. To support the development of this approach, we have developed the Manually Annotated Alternatively Spliced Events (MAASE) database system, which is a unique alternative splicing information resource designed specifically with experimentalists in mind. MAASE is an ...

We present a generic means of interfacing XML documents and clinical systems. The interface has been developed to allow the integration of best practice guidance information within prescribing systems. The interface has the following characteristics: (1) integrating developers do not have to interpret the structure of the XML documents, (2) ...

Ecoregion classification systems are increasingly used for policy and management decisions, particularly among conservation and natural resource managers. A number of ecoregion classification systems are currently available, with each system defining ecoregions using different classification methods and different types of data. As a result, each classification system describes a unique ...

The purpose of this system is to establish virtual medical school (VMS) as the platform of e-learning center, which integrates collaborative and self-directed learning environment by virtual group, classroom and library, and automatically converts valuable clinical case from Hospital Information System (HIS) database into virtual patient by online authoring tools ...

The National Library of Medicine (NLM) produces annual editions of the Medical Subject Headings (MeSH). Translations of MeSH are often done to make the vocabulary useful for non-English users. However, MeSH translators have encountered difficulties with entry vocabulary as they maintain and update their translation. Tracking MeSH changes and updating ...

During the last four decades, about 400 people have been in Space, since Yuri Gagarin was sent in 1961 as the first human into Earth orbit. From the very beginning, the circulatory system of astronauts (meaning heart, vascular system, body fluid distribution and balance, and the kidney) was central to ...

To re-examine the validity of the medical knowledge that are embedded in the legacy system, we translated a Medical Logic Module (MLM) for hyperkalemia patient screening into the GuideLine Interchange Format (GLIF).

This is the final part of a series of papers that review the evolution of the military casualty evacuation system in the 20th Century. This paper draws together the themes that have been presented in the previous papers to describe the mandatory functions of such a system. The forward surgical ...

The Unified Medical Language System and the Gene Ontology are among the most widely used terminology resources in the biomedical domain. However, when we evaluate them...

Recently developed versatile biodegradable polymeric biomaterial offer new therapeutic options in numerous medical fields. Biocompatibility is a crucial requirement for the biomedical application of biomaterials, including the sterilization of these materials with the use of accepted protocols. Ethylene-oxide (EO) and low-temperature plasma (LTP) sterilization are frequently used low-temperature sterilization technologies ...

Current medical robots have nothing in common with the anthropomorphic robots in science fiction classics. They are in fact, manipulators, working on a master-slave principle. Robots can be defined as "automatically controlled multitask manipulators, which are freely programmable in three or more spaces." The success of robots in surgery is ...

OBJECTIVE: To develop a 'quality use of medicines' coding system for the assessment of pharmacists' medication reviews and to apply it to an appropriate cohort. METHOD: A 'quality use of medicines' coding system was developed based on findings in the literature. These codes were then applied to 216 (111 intervention, ...

One popular new method for building safeguards into the medication administration process is the use of a bar-coded medication administration (BCMA) system. Clinician use the system's bar-code scanner to scan labels on the medication packaging and on the patient's identification wristband. In this way, the system verifies that administered medications ...

In order to make long-term medical treatment with the use of an artificial heart effective, we developed the Tsukuba remote monitoring system, which enables medical staff to manage the physiological condition of patients and the driving condition of the artificial heart at anytime from a remote place. This remote monitoring ...

A plethora of literature describes the impact of the P450 enzyme system, but this information is limited regarding its relevancy to nursing practice. However, oncology nurses providing palliative symptom management must have a working knowledge of the P450 enzyme system to recognize the variability that exists among individual medication reactions ...

Cedars-Sinai Medical Center in Los Angeles revamped its billing system to better meet patients' needs for comprehensible billing information. After changing its billing format and processes, the provider's phone-call volume decreased 31 percent, translating into an annual savings of more than $250,000. Patient feedback regarding the new system has been ...

Many health care facilities have information systems with support for medical record keeping, finance and workflow, however, it is widely recognized that one of the keys to cost reduction and service improvement in national health care lies in the integration of medical information system. Integrating information not only improves care ...

Many systemic agents are used in the treatment of psoriasis. They provide good control of psoriasis in the majority of patients and have improved their life quality indices. Frequently, combination therapy is utilized to synergize the efficacy of these medications. Many dermatologists are hesitant in prescribing systemic agents because of ...

The origin of the Gompertz function G(t)=G(0)e(b/a(1-e(-at))) widely applied to fit the biological and medical data, particularly growth of organisms, organs, and tumors is analyzed. It is shown that this function is a solution of a time-dependent counterpart of the Schrödinger equation for the Morse oscillator with anharmonicity constant equal ...

Medical support in a Martian expedition will be within the scope of crew responsibilities and maximally autonomous. Requirements to the system of diagnostics in this mission include considerable use of means and methods of visualization of the main physiological parameters, telemedicine, broad usage of biochemical analyses (including "dry" chemistry), computerized ...

The evolution of the number of medical specialists in the Spanish Health System has been and continues to be determined by various factors. Among them, it is worth pointing out the lack of restrictive policies on the number of entrants into colleges of medicine, as well as the scarcity of ...

OBJECTIVE: To evaluate patient acceptance of an automated medical information system specific to headache. BACKGROUND: Studies suggest that automated tools may help health care delivery systems to be efficient and effective, but patient satisfaction remains a major concern. METHODS: We adapted our software reuse reference model and Unified Modeling Language ...

Assessing actual abuse of prescribed medications requires postmarketing surveillance. In this article we discuss general systems of postmarketing surveillance that exist as of the end of 2002 in the United States and two medication-specific surveillance systems that were devised and tested. The two specific surveillance systems are compared with limitations ...

OBJECTIVE: To implement a computerized system to gather and transmit medical record information from six sites to a centralized database for two cancer prevention studies. METHODS: Microsoft Access 97 was selected as the application for the system. Sites purchased Access and hardware meeting technical specifications required for the system. A ...

In the period 1997-2001 the Academic Medical Centre in Amsterdam implemented the computerized physician medication order entry (CPmOE) system Medicator. This article describes several important aspects of this program: technological architecture, features, implementation project, authentication and training, continuous support, human resource investments, route of prescription, logistics and administration. Furthermore important ...