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Sagir Afrin A Department of Anesthesia and Critical Care, Armed Forces Medical College-Pune and Command Hospital (SC), Pune, - - 2014
Local anesthetics (LAs) are extensively used in clinical practice by both anesthesiologists and non-anesthesiologists and are often associated with systemic toxicity. We hypothesize that this awareness is inadequate among medical specialists and entails a risk of misdiagnosis and underreporting of such events. We therefore conducted a cross-sectional questionnaire-based study to ...
Lynch Cheryl P - - 2014
Multi-morbidity, or the presence of multiple chronic diseases, is a major problem in clinical care and is associated with worse outcomes. Additionally, the presence of mental health conditions, such as depression, anxiety, etc., has further negative impact on clinical outcomes. However, most health systems are generally configured for management of ...
Russell Bethany J BJ Centre for Palliative Care, St Vincent's Hospital, Melbourne, Victoria, - - 2014
To document pro re nata (PRN) prescribing practices and to identify patterns with respect to clinical characteristics and the medications prescribed. Prospective consecutive case note review. Two interrelated consultative hospice and palliative care services in regional Victoria, Australia. Terminally ill inpatients and community-based individuals (N = 203) at the time of referral ...
de Mauleon Adelaide A Department of Geriatric Medicine, Gerontopole, Toulouse University Hospital, INSERM 1027, Toulouse, - - 2014
To determine factors associated with the antipsychotic (AP) prescription for people with dementia (PwD) recently admitted to institutional long-term care facilities (LTCFs) and to ascertain differences in the use of this medication in 8 European countries. An exploratory cross-sectional study. LTCFs from 8 European countries (Estonia, Finland, France, Germany, The ...
Stortecky Stefan S Department of Cardiology, Bern University Hospital, Bern, - - 2014
Up to 40% of ischaemic strokes are cryptogenic. A strong association between cryptogenic stroke and the prevalence of patent foramen ovale (PFO) suggests paradoxical embolism via PFO as a potential cause. Randomized trials failed to demonstrate superiority of PFO closure over medical therapy. Randomized trials comparing percutaneous PFO closure against ...
Nylund Cade M CM Department of Pediatrics, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD. Electronic address: - - 2014
Multiple studies have confirmed associations between acid suppression medication and Clostridium difficile infections (CDIs) in adults. Therefore, we sought to evaluate an association between acid suppression medications and CDI in children. A retrospective self-controlled case series was performed utilizing billing records from the TRICARE Management Activity military health system database. ...
Galéra Cédric C Cédric Galéra, MD, PhD, University of Bordeaux, Department of Child and Adolescent Psychiatry, Charles Perrens Hospital and INSERM, The Bordeaux School of Public Health (Institut de Santé Publique, d'Epidémiologie et de Développement), Centre INSERM U897, Epidemiology-Biostatistics, Bordeaux, France; Jean-Baptiste Pingault, PhD, Research Unit on Children's Psychosocial Maladjustment, University of Montreal and Sainte-Justine Hospital, Montreal, Canada and INSERM U669, Paris, France; Grégory Michel, PhD, University of Bordeaux, Psychology and Quality of Life, Bordeaux, France; Manuel-Pierre Bouvard, MD, University of Bordeaux, Department of Child and Adolescent Psychiatry, Charles Perrens Hospital, Bordeaux, France; Maria Melchior, ScD, INSERM U1018, Centre for Research in Epidemiology and Population Health, Epidemiology of Occupational and Social Determinants of Health, Villejuif, France; Bruno Falissard, MD, PhD, INSERM U669, Paris, France; Michel Boivin, PhD, International Laboratory for Child and Adolescent Mental Health, Department of Psychology, Laval University, Quebec City, Canada and Institute of Genetic, Neurobiological and Social Foundations of Child Development, Tomsk State University, Russian Federation; Richard E. Tremblay, PhD, Research Unit on Children's Psychosocial Maladjustment, University of Montreal and Sainte-Justine Hospital, Montreal, International Laboratory for Child and Adolescent Mental Health, University of Montreal, Montreal, Departments of Pediatrics, Psychiatry, and Psychology, University of Montreal, Montreal, Canada and School of Public Health, Physiotherapy, and Population Sciences, University College Dublin, Ireland and Institute of Genetic, Neurobiological and Social Foundations of Child Development, Tomsk State University, Russian Federation; Sylvana M. Côté, PhD, Research Unit on Children's Psychosocial Maladjustment, University of Montreal and Sainte-Justine Hospital, Montreal and International Laboratory for Child and Adolescent Mental Health, University of Montreal, Montreal, Canada and Institute of Genetic, Neurobiological and Social Foundations of Child Development, Tomsk State University, Russian - - 2014
Background The impact of longitudinal psychiatric comorbidity, parenting and social characteristics on attention-deficit hyperactivity disorder (ADHD) medication use is still poorly understood. Aims To assess the baseline and longitudinal influences of behavioural and environmental factors on ADHD medication use. Method Survival regressions with time-dependent covariates were used to model data ...
Saarelainen Laura K LK Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, - - 2014
Potentially inappropriate medication (PIM) use has been associated with an increase in adverse drug events, hospitalization and mortality. This study investigated the prevalence and factors associated with PIM use in patients presenting to a medical oncology outpatient clinic. Consecutive patients (n=385) aged ≥70years referred to a medical oncology outpatient clinic ...
Chen Lena M LM Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor2VA Ann Arbor Healthcare System, Ann Arbor, Michigan3Center for Healthcare Outcomes & Policy, University of Michigan, Ann Arbor4Institute for Healthcare - - 2014
Payments around episodes of inpatient surgery vary widely among hospitals. As payers move toward bundled payments, understanding sources of variation, including use of medical consultants, is important. To describe the use of medical consultations for hospitalized surgical patients, factors associated with use, and practice variation across hospitals. Observational retrospective cohort ...
Park Haesuk H University of Florida College of Pharmacy, HPNP Bldg, Rm. 3325, Gainesville, FL 32611. - - 2014
The implementation of Medicare Part D provided insurance coverage for outpatient medications, but when persons reach the "gap," they have very limited or no medication insurance coverage until they reach a second threshold for catastrophic coverage. In addition, some patients have a low-income subsidy (LIS), and their out-of-pocket costs do ...
Iyengar Reethi N RN Express Scripts, 4600 N. Hanley Rd., PTIC08, St. Louis, MO 63134. - - 2014
Medication adherence, defined as taking medications as prescribed, is a key component in controlling disease progression and managing chronic illnesses such as diabetes, hypertension, and high blood cholesterol. These diseases constitute 3 of the top 5 most prevalent conditions among Medicare beneficiaries, warranting further attention to find ways to promote ...
Couto Joseph E JE Cigna Healthcare, 900 Cottage Grove Rd., B8MM, Bloomfield, CT 06002. - - 2014
Previous literature has emphasized the importance of cost sharing, health literacy, socioeconomic status, cognitive function, disease burden, and polypharmacy as some of the determinants of medication adherence. Little research has been published examining disparities in adherence rates when comparing different regions of the United States. To examine the impact of ...
Francis Brian A BA From Doheny Eye Institute (Francis), Department of Ophthalmology, David Geffen School of Medicine of the University of California Los Angeles, and the Department of Preventative Medicine and Biostatistics (Dustin), Keck School of Medicine of the University of Southern California, Los Angeles, California; Albert Einstein College of Medicine, Bronx and Nassau University Medical Center (Berke), and East Meadow, the Ophthalmic Consultants of Long Island (Berke), Lynbrook, New York; Ophthalmic Consultants of Connecticut (Noecker), Fairfield, Connecticut, USA. Electronic address: - - 2014
To compare the outcomes of combined endoscopic cyclophotocoagulation (ECP) and phacoemulsification cataract extraction versus cataract extraction alone in eyes with medically controlled open-angle glaucoma (OAG) and visually significant cataract. Clinical practices of glaucoma specialists and comprehensive ophthalmologists. Prospective nonrandomized matched-control study. Consecutive patients with medically controlled OAG and visually significant ...
Pickett Christopher A CA Cardiology Service (Drs. Ferguson, Pickett, and Villines) and Interventional Cardiology (Dr. Ferguson), Walter Reed National Military Medical Center, Bethesda, Maryland 20889; and Cardiovascular Division, Department of Medicine (Dr. Hulten), Brigham and Women's Hospital, Boston, Massachusetts - - 2014
Of cryptogenic stroke patients younger than 55 years of age, up to 61% have had a patent foramen ovale (PFO). Observational studies have revealed reductions in recurrent neurologic events through PFO closure versus medical therapy, and randomized controlled trials have shown nonsignificant trends toward benefit. We systematically searched for randomized ...
Kuschel Bernhard M BM Department of Public Health Sciences, Karolinska Institutet, Stockholm, - - 2014
Older people not only consume more medication but they also represent a group at high risk for adverse effects such as injurious falls. This study examines the association between the medications most commonly prescribed to older people in Sweden and fall injuries. This is a population-based, matched, case-control study of ...
Lloyd C E CE Open University, Faculty of Health and Social Care, Milton - - 2014
To investigate concordance with medication, as assessed at baseline and at 1- and 2-year follow-up, and to examine factors associated with non-concordance in a UK-resident South-Asian population. Data from the UK Asian Diabetes Study were analysed. Concordance with medications was assessed and recorded at three time points during the study. ...
Vaidya Varun V 1 University of Toledo College of Pharmacy , Toledo, - - 2014
Abstract Sleep deprivation and disturbances can result in lowered productivity and increased errors/accidents. Little is known about population characteristics associated with the use of sleep medications. The objective of this study was to investigate the association of sociodemographic factors with the use of sleep medications in the US population. This ...
Lee Jacky W Y JW *Department of Ophthalmology, University of Hong Kong, †Department of Ophthalmology, Caritas Medical Centre ‡Department of Ophthalmology, Queen Mary Hospital, Hong Kong, SAR, People's Republic of - - 2014
The purpose of this study was to investigate the efficacy of selective laser trabeculoplasty (SLT) in the treatment of normal tension glaucoma (NTG). This prospective cohort study recruited consecutive cases of NTG on antiglaucoma medication. Cases were excluded for previous glaucoma surgery or laser. All patients underwent a 1-month washout ...
Hoffman Andrea S AS Department of Paediatrics, Division of Developmental Paediatrics, Holland Bloorview Kids Rehabilitation Hospital, University of Toronto, 150 Kilgour Road, M4G 1R8, Toronto, Canada, - - 2014
Studies of elective surgical procedures indicate that cancellation is common and preventable. Little is known about cancellation of anesthesia-supported elective diagnostic imaging. To describe the reasons for same-day cancellation of MRI studies performed under sedation or anesthesia and identify patient characteristics associated with cancellations. This case-control study was carried out ...
Manias Elizabeth E Deakin University, Burwood, VIC, Australia The University of Melbourne, Parkville, VIC, Australia - - 2014
To systematically examine the research literature to identify which interventions reduce medication errors in pediatric intensive care units. Databases were searched from inception to April 2014. Studies were included if they involved the conduct of an intervention with the intent of reducing medication errors. In all, 34 relevant articles were ...
Leung Victoria C VC *Faculty of Medicine †Department of Ophthalmology and Vision Sciences ‡Dalla Lana School of Public Health, University of Toronto, Toronto, ON §Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, - - 2014
To investigate the relationship between sociodemographic factors and nonpersistence with topical glaucoma medication. This was a retrospective, observational cohort study. We invited glaucoma patients on medical therapy from a general ophthalmology practice to complete a standardized questionnaire between November 2011 and April 2012. Nonpersistence was defined as having ≥1 gaps ...
Devlin Megan K MK Department of Medicine, University of Toronto, Toronto, Ontario, - - 2014
Handover is the process of transferring pertinent patient information and clinical responsibility between health care practitioners. Few studies have examined morning handover from the overnight trainee to the daytime team. To characterize current morning handover practices in 2 academic medical centers by assessing the frequency of omissions of clinically important ...
Brown James C JC Department of Public and Occupational Health, EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands; UCT/MRC Research Unit for Exercise Science and Sports Medicine, Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. Electronic address: - - 2014
Rugby Union ("rugby") is a popular sport with high injury risk. Burden of injury is described by the incidence and severity of injury. However reports have ignored the monetary cost of injuries. Therefore the aim of this study was to describe the monetary cost associated with youth rugby injuries. This ...
Maggiore Ronald J RJ Portland Veterans Affairs Medical Center and Oregon Health & Science University, Portland, - - 2014
To evaluate the prevalence of polypharmacy and potentially inappropriate medication (PIM) use and the association between these and chemotherapy-related adverse events in older adults with cancer undergoing chemotherapy. Secondary analysis of prospectively collected data. Outpatient oncology clinics in seven academic medical centers. Adults aged 65 and older with cancer undergoing ...
Yin H Shonna HS Department of Pediatrics, New York University School of Medicine and Bellevue Hospital Center, New York, New York; - - 2014
Adopting the milliliter as the preferred unit of measurement has been suggested as a strategy to improve the clarity of medication instructions; teaspoon and tablespoon units may inadvertently endorse nonstandard kitchen spoon use. We examined the association between unit used and parent medication errors and whether nonstandard instruments mediate this ...
Albrecht J S JS Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, 220 Arch Street, 12th floor, Room 01-234, Baltimore, MD, 21201, USA, - - 2014
Little is known regarding the prevalence or risk factors for non-comprehension and non-compliance with discharge instructions among older adults. To quantify the prevalence of non-comprehension and non-compliance with discharge instructions and to identify associated patient characteristics. Prospective cohort study. Four hundred and fifty adults aged ≥ 65 admitted to medical ...
Marie Chater Angel A a Centre for Behavioural Medicine, UCL School of Pharmacy, University College - - 2014
Abstract Objective: Nonadherence to phosphate binding medication (PBM) compromises the efficacy of treatment for chronic kidney disease (CKD), but its causes are poorly understood. This study sought to explore patient attitudes towards PBM and to evaluate the utility of the Necessity-Concerns Framework for understanding adherence to PBM. Design: A sample ...
Hampton Lee M LM Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, - - 2014
In 2011, an estimated 26.8 million US adults used prescription medications for mental illness. To estimate the numbers and rates of adverse drug event (ADE) emergency department (ED) visits involving psychiatric medications among US adults between January 1, 2009, and December 31, 2011. Descriptive analyses of active, nationally representative surveillance ...
Elliot Kathleen K Section on Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, NC, USA. Electronic address: - - 2014
We retrospectively evaluated the prognostic significance of polypharmacy and inappropriate medication use among 150 patients >60 years of age receiving induction chemotherapy for acute myelogenous leukemia (AML). After adjustment for age and comorbidity, increased number of medications at diagnosis (≥4 versus ≤1) was associated with increased 30-day mortality (OR=9.98, 95% ...
Mixon Amanda S AS Department of Veterans Affairs, Tennessee Valley Healthcare System Geriatric Research Education and Clinical Center, Nashville, Tennessee; Section of Hospital Medicine, Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University, Nashville, Tennessee; Center for Health Services Research, Vanderbilt University, Nashville, Tennessee. Electronic address: - - 2014
To examine the association of patient- and medication-related factors with postdischarge medication errors. The Vanderbilt Inpatient Cohort Study includes adults hospitalized with acute coronary syndromes and/or acute decompensated heart failure. We measured health literacy, subjective numeracy, marital status, cognition, social support, educational attainment, income, depression, global health status, and medication ...
Kisambu J J *Uganda Prisons Services, Kampala, - - 2014
<sec id="st1"> <title>OBJECTIVE</title> To estimate the levels of adherence to anti-tuberculosis medications and associated risk factors in a pastoral community practising transhumance in North-Eastern Uganda. </sec> <sec id="st2"> <title>DESIGN</title> A cross-sectional retrospective study of a cohort of tuberculosis (TB) patients and their community volunteers registered from August 2008 to July ...
McAdam-Marx Carrie C University of Utah, 30 S. 2000 E., Rm. 4980, Salt Lake City, UT 84112. - - 2014
Managed care organizations put great effort into managing the population of patients with type 2 diabetes mellitus (T2DM) because of the health and economic burden of this disease. In patients with T2DM, weight loss and glycemic control are primary treatment aims to help improve patient outcomes, but these goals are ...
Porter Evelyn E University of California San Francisco, Department of Emergency Medicine, San Francisco, - - 2014
The objective of our study was to estimate the incidence of prescribing medication errors specifically made by a trainee and identify factors associated with these errors during the simulated resuscitation of a critically ill child. The results of the simulated resuscitation are described. We analyzed data from the simulated resuscitation ...
Muntner Paul P Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: - - 2014
Low statin adherence and discontinuation of statins are common in patients with coronary heart disease. We hypothesized that low antihypertensive medication adherence would be associated with future statin discontinuation and low adherence in patients initiating statins. Using a 5% national sample of Medicare beneficiaries, we conducted a cohort study of Medicare ...
Li Xiaojuan X Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, - - 2014
Epidemiologic studies of prescription medications increasingly rely on large administrative health care databases. These data do not capture patients' use of medication samples. This could potentially bias studies of short-term effects where date of initiation may be inaccurate. To assess the extent of sample use among patients initiating statin therapy. ...
Bailit Jennifer L JL Department of Obstetrics and Gynecology of Case Western Reserve University-MetroHealth Medical Center, Cleveland, OH. Electronic address: - - 2014
To compare maternal and neonatal outcomes in nulliparous women with non-medically indicated inductions at term versus those expectantly managed. Data were obtained from maternal and neonatal charts for all deliveries on randomly selected days across 25 US hospitals over a three-year period. A low-risk subset of nulliparas with vertex non-anomalous ...
Friedman Benjamin W BW Department of Emergency Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, NY, USA - - 2014
Published data from 1998 revealed that most patients treated for migraine in an emergency department received opioids. Over the intervening years, a large body of evidence has emerged demonstrating the efficacy and safety of non-opioid alternatives. Expert opinion during these years has cautioned against use of opioids for migraine. Our ...
Peterson Cora C National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia; - - 2014
Health consequences of shaken baby syndrome, or pediatric abusive head trauma (AHT), can be severe and long-lasting. We aimed to estimate the multiyear medical cost attributable to AHT.METHODS: Using Truven Health MarketScan data, 2003-2011, we identified children 0 to 4 years old with commercial or Medicaid insurance and AHT diagnoses. ...
Zedler Barbara B Venebio Group, Richmond, Virginia, - - 2014
Prescription opioid use and deaths related to serious toxicity, including overdose, have increased dramatically in the United States since 1999. However, factors associated with serious opioid-related respiratory or central nervous system (CNS) depression or overdose in medical users are not well characterized. The objective of this study was to examine ...
Sri-On Jiraporn J Emergency Department, Massachusetts General Hospital, Boston, - - 2014
Hospital crowding and emergency department (ED) boarding are large and growing problems. To date, there has been a paucity of information regarding the quality of care received by patients boarding in the ED compared with the care received by patients on an inpatient unit. We compared the rate of delays ...
Hawkins Lee Ann LA Indiana Wesleyan University, Marion, IN, USA; VA Loma Linda Healthcare System, Loma Linda, CA, USA. Electronic address: - - 2014
(a) To evaluate efficacy of a pictorial medication sheet to improve adherence in veterans with heart failure (HF) and cognitive impairment (CI); (b) to describe acceptance of the intervention. CI is prevalent in HF and is associated with worsened medication adherence. The Veteran's Administration has developed a medication image library; ...
Rajan Shobana S Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Avenue, E-31, Cleveland, OH 44195, - - 2014
Hypertension is common in deep brain stimulator (DBS) placement predisposing to intracranial hemorrhage. This retrospective review evaluates factors predicting incremental antihypertensive use intraoperatively. Medical records of Parkinson's disease (PD) patients undergoing DBS procedure between 2008-2011 were reviewed after Institutional Review Board approval. Anesthesia medication, preoperative levodopa dose, age, preoperative use ...
Solomon D H DH Division of Pharmacoepidemiology, Brigham and Women's Hospital, Boston, MA, USA, - - 2014
Among 125,954 new users of osteoporosis (OP) medications, 77 % of subjects stopped OP medications, and 23 % of subjects added or started a new OP medication during follow-up, with the first addition or start of a new OP medication occurring in a mean of 739 days after original OP treatment. We described ...
Mochari-Greenberger Heidi H Department of Medicine, Columbia University Medical Center, New - - 2014
In the United States, hypertension and diabetes are more common among blacks and Hispanics than among others; the comorbidity is associated with worse clinical outcomes than each condition alone. Racial/ethnic differences in outcomes may be related to differential uptake of antihypertensive therapies, but data to evaluate this in real-world settings ...
Nuckols Teryl K - - 2014
The Health Information Technology for Economic and Clinical Health (HITECH) Act subsidizes implementation by hospitals of electronic health records with computerized provider order entry (CPOE), which may reduce patient injuries caused by medication errors (preventable adverse drug events, pADEs). Effects on pADEs have not been rigorously quantified, and effects on ...
Murphy Gaetanne K - - 2014
Rural residents face numerous barriers to healthcare access and studies suggest poorer health outcomes for rural patients. Therefore we undertook a systematic review to determine if cardiovascular medication utilization and adherence patterns differ for rural versus urban patients. A comprehensive search of major electronic datasets was undertaken for controlled clinical ...
Suehs Brandon T BT Comprehensive Health Insights, Inc., 325 W. Main St., WFP6W, Louisville, KY 40202. - - 2014
Varenicline, a nicotinic acetylcholine receptor partial agonist, is a pharmacotherapy indicated for smoking cessation treatment. To date, no research has examined the relationship between out-of-pocket (OOP) expense and varenicline adherence among Medicare beneficiaries. To (a) characterize medication utilization patterns of varenicline among Medicare members newly initiated on varenicline and (b) ...
Razali S M SM Discipline of Psychological and Behavioural Medicine, Faculty of Medicine, Universiti Teknologi Mara, Sungai Buloh Campus, 47000 Sungai Buloh, Selangor, - - 2014
OBJECTIVE. Adherence to medication is essential for maximising the outcomes of patients with schizophrenia as the consequences of poor adherence are devastating. The study aimed to compare medication adherence between patients with relapse schizophrenia and those attending psychiatric follow-up clinics, and to determine the factors affecting adherence. METHODS. This was ...
Patterson P Daniel - - 2014
Abstract Objectives. We sought to test reliability of two approaches to classify adverse events (AEs) associated with helicopter EMS (HEMS) transport. Methods. The first approach for AE classification involved flight nurses and paramedics (RN/Medics) and mid-career emergency physicians (MC-EMPs) independently reviewing 50 randomly selected HEMS medical records. The second approach ...
Wimmer Barbara Caecilia BC Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA, Australia, - - 2014
Older people often take multiple medications. It is a policy priority to facilitate older people to stay at home longer. Three-quarters of nursing home placements in the US are preceded by a hospitalization. To investigate the association between polypharmacy and medication regimen complexity with hospital discharge destination among older people. ...
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