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Wang Chuan C Department of Pediatric Cardiovascular Disease, West China Second University Hospital, Sichuan University, No. 20, Section 3, RenminNanLu Road, Chengdu, 610041, Sichuan, - - 2014
The fundamental etiology of the majority of nonsyndromic congenital heart defects is commonly believed to involve the interaction of multiple environmental and genetic factors. This study aimed to explore the joint effects of fetal 3435 C>T polymorphism in the ABCB1 gene and maternal medication use on the risk of septal ...
Zakharyan Roksana R Institute of Molecular Biology, National Academy of Sciences of the Republic of Armenia (NAS RA), 7 Hasratyan, 0014, Yerevan, Armenia. Electronic address: - - 2014
A growing number of studies implicate brain-derived neurotrophic factor (BDNF), an important promoter of synaptic transmission and neural plasticity, in the pathogenesis of schizophrenia. However, the existing data are controversial, that may reflect population differences between studied groups. In the present study we performed comparative analysis of BDNF plasma levels ...
Gold Mark S MS Department of Psychiatry, School of Medicine and McKnight Brain Institute, University of Florida, Gainesville, FL. - - 2014
Attention deficit/hyperactivity disorder (ADHD) is present in 8% to 12% of children, and 4% of adults worldwide. Children with ADHD can have learning impairments, poor selfesteem, social dysfunction, and an increased risk of substance abuse, including cigarette smoking. Overall, the rate of treatment with medication for patients with ADHD has ...
Altar C Anthony - - 2013
Abstract Adverse events, response failures and medication non-compliance are common in patients receiving medications for the treatment of mental illnesses. A systematic literature review assessed whether pharmacokinetic (PK) or pharmacodynamic (PD) responses to 26 commonly prescribed antipsychotic and antidepressant medications, including efficacy or side effects, are associated with nucleotide polymorphisms ...
Berrettini Wade - - 2013
Alcohol addiction is one of the most common and devastating diseases in the world. Given the tremendous heterogeneity of alcohol-addicted individuals, it is unlikely that one medication will help nearly all patients. Thus, there is a clear need to develop predictors of response to existing medications. Naltrexone is a μ-opioid ...
Oetjens Matthew T MT Center for Human Genetics Research & Department of Molecular Physiology & Biophysics, Vanderbilt University, 2215 Garland Avenue, 519 Light Hall, Nashville, TN 37232-0700, - - 2013
The ADME Core Panel assays 184 variants across 34 pharmacogenes, many of which are difficult to accurately genotype with standard multiplexing methods. We genotyped 326 frequently medicated individuals of European descent in Vanderbilt's biorepository linked to de-identified electronic medical records, BioVU, on the ADME Core Panel to assess quality and ...
Mudge A M AM Internal Medicine and Aged Care, Royal Brisbane and Women's Hospital, Brisbane, Australia. - - 2013
Clinical practice guidelines have been developed to improve screening, prevention and management of delirium. To implement delirium guidelines in general medical patients to reduce incidence and duration of delirium and improve outcomes in delirious patients. Implementation was led by a multidisciplinary team of clinicians and project staff on one medical ...
Sewell Justin L JL Center for Innovation in Access and Quality, Division of Gastroenterology and Hepatology, San Francisco General Hospital, Department of Medicine, University of California San Francisco, San Francisco, California 94143, - - 2013
Race and socioeconomic status (SES) significantly affect the content and delivery of healthcare for multiple chronic disease states. Inflammatory bowel disease (IBD) is a set of complex, chronic diseases with the potential for significant morbidity if the content or delivery of healthcare is suboptimal. However, the literature related to race, ...
Olfson Mark - - 2012
CONTEXT Although antipsychotic treatment has recently increased, little is known about how this development has differentially affected the office-based care of adults and young people in the United States. OBJECTIVE To compare national trends and patterns in antipsychotic treatment of adults and youths in office-based medical practice. DESIGN Trends between ...
Lorenzo Cherubino Di - - 2012
Background:Medication overuse headache (MOH) is a disabling health problem. Convincing evidence attributes a pathophysiologic role to central sensitization. By recording somatosensory evoked potentials (SSEPs) in patients with MOH, we observed increased sensitization and deficient habituation to repetitive sensory stimuli consistent with drug overuse. The renin-angiotensin system in the brain seems ...
Glanz Karen - - 2012
To determine the efficacy of an automated, interactive, telephone-based health communication intervention for improving glaucoma treatment adherence among patients in 2 hospital-based eye clinics. A total of 312 patients with glaucoma (18-80 years of age) were enrolled in a randomized controlled trial at 2 eye clinics located in hospitals in ...
Siegler Aaron J - - 2012
By removing the foreskin, medical male circumcision (MMC) reduces female to male heterosexual HIV transmission by approximately 60 %. Traditional circumcision has higher rates of complications than MMC, and reports indicate unsanitized instruments are sometimes shared across groups of circumcision initiates. A geographically stratified, cluster survey of acceptability of MMC and ...
McCabe Sean Esteban - - 2012
OBJECTIVES To determine the prevalence of medical and nonmedical use of prescription opioids among high school seniors in the United States and to assess substance use behaviors based on medical and nonmedical use of prescription opioids. DESIGN Nationally representative samples of high school seniors (modal age 18 years) were surveyed ...
Nachiappan Arun C - - 2012
Medical physics instruction for diagnostic radiology residency at our institution has been redesigned with an interactive and image-based approach that encourages clinical application. The new medical physics curriculum spans the first 3 years of radiology residency and is integrated with the core didactic curriculum. Salient features include clinical medical physics ...
Moore Brent A - - 2012
Counseling and medication adherence can affect opioid agonist treatment outcomes. We investigated the impact of 2 counseling intensities and 2 medication-dispensing methods in patients receiving buprenorphine in primary care. In a 12-week trial, patients were assigned to physician management (PM) with weekly buprenorphine dispensing (n = 28) versus PM and ...
Voltmer E - - 2012
Background: Longitudinal data about the development of health risks and resources in relation to the performance of medical students are limited. Aims: To evaluate the development of study-related experience and the correlation to performance. Method: Medical students in the first (2006), second (2008), and fifth years (2011) of their studies ...
Kwon Obin - - 2012
CONTEXT: It was previously reported in Korea that there were 1.4 case per million per year of acromogly. This was low in comparison to the extrapolated values of western European countries. We expected that the incidence of acromegaly would be much higher now due to recently improved medical facilities, diagnostic ...
Cox Daniel J - - 2012
Objective: To address a major barrier of medication noncompliance for individuals with ADHD, the authors present the ADHD Medication Attitude Scale (AMAS) with initial psychometric analyses and discriminant validity data. Method: The AMAS was posted on ADHD websites, along with questions about demographics and medication usage over a 6-month period. ...
Egede Leonard E LE Center for Disease Prevention and Health Interventions for Diverse Populations, Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina, USA. - - 2012
To examine the longitudinal effects of medication nonadherence (MNA) on key costs and estimate potential savings from increased adherence using a novel methodology that accounts for shared correlation among cost categories. Veterans with type 2 diabetes (740,195) were followed from January 2002 until death, loss to follow-up, or December 2006. ...
Faridi Kia - - 2012
Both medication non-adherence and co-morbid cannabis abuse are associated with poor clinical outcome in first episode psychosis (FEP). The nature of interaction between adherence to medication and continued cannabis use remains unexplored. The objectives of this study were to examine variation in medication adherence associated with cessation or continuation of ...
Baker J F - - 2012
INTRODUCTION: The aim of this study was to determine the incidence of concussion among a cohort of male under 20 rugby players and assess basic knowledge and attitudes. METHODS: Under 20 age group, players were recruited from local clubs as well as the national academy system. Players were asked to ...
Fransen A F - - 2012
To determine whether obstetric team training in a medical simulation centre improves the team performance and utilisation of appropriate medical technical skills of healthcare professionals. Cluster randomised controlled trial. The Netherlands. The obstetric departments of 24 Dutch hospitals. The obstetric departments were randomly assigned to a 1-day session of multiprofessional ...
Ouma Mercy N - - 2012
OBJECTIVE: To describe the experience at a single facility regarding single-use emergency medication kits to treat obstetric emergencies in a resource-poor setting. METHODS: A retrospective study was conducted between October 2009 and October 2010 using data from the medical records of all patients treated with a single-use obstetric emergency medical ...
Khadadah Mousa - - 2012
Objective: To evaluate the direct costs of treating asthma in Kuwait. Materials and Methods: Population figures were obtained from the 2005 census and projected to 2008. Treatment profiles were obtained from the Asthma Insights and Reality for the Gulf and Near East (AIRGNE) study. Asthma prevalence and unit cost estimates ...
Bhattacharyya Neil - - 2012
ObjectiveTo determine characteristics and trends for outpatient otolaryngology visits and practices in the United States.Study DesignCross-sectional analysis of national survey database.SettingAmbulatory care settings in the United States.MethodsOutpatient otolaryngology records from 2005 to 2009 were extracted from the National Ambulatory Medical Care Survey. Visit characteristics were assessed for patient type (established ...
Wahab Mohd Shahezwan Abd - - 2012
Background The elderly population is increasing worldwide. Due to age-related physiological changes that affect the pharmacokinetics and pharmacodynamics of drugs, the elderly are predisposed to adverse drug reactions. Prescribing of potentially inappropriate medications (PIMs) has been found to be prevalent among the elderly and PIM use has been associated with ...
Lantz Björn - - 2012
Scand J Caring Sci; 2012 Parental interaction with infants treated with medical technology Background:  It is well established that parents must interact with their new-born babies to facilitate attachment. However, very little is known about how parents perceive different types of medical technology products commonly used in the neonatal intensive ...
Marquez Gabriel E - - 2012
Purpose: The aim of this study was to identify practices of self-medication in the treatment of ocular conditions and to identify a profile of patients who self-medicate. Methods: We conducted a cross-sectional descriptive survey of patients, over the age of 17 years seen in our ophthalmology practice in Cordoba, Argentina. ...
Fitzgerald Rebecca - - 2012
A 40-year-old Asian female presented complaining of looking tired. She had no significant medical history and was in good health. She had received botulinum toxin injection in the glabellar area routinely over the last several years but had no history of injectable fillers. J Drugs Dermatol. 2012;11(suppl 8):s9-s11.
Miller Andrew C - - 2012
The process of medical clearance screening for patients with psychiatric chief complaints has not been standardized. To investigate the validity of a triage algorithm for psychiatric screening (TAPS) as a method to screen for the absence of acute medical illness in these patients. The current study was a structured, retrospective ...
Evans R Scott - - 2012
ABSTRACT BACKGROUND: As peripherally inserted central catheter (PICC) use has increased, so has the upper extremity deep venous thrombosis (DVT) rate. PICC diameter may pose the most modifiable risk for PICC-associated DVT. METHODS: A three year prospective observational study of all PICC insertions by a specially trained and certified team ...
Gill Richdeep S - - 2012
Worldwide, more than 1.7 billion individuals may be classified as overweight and are in need of appropriate medical and surgical treatments. The primary goal of a comprehensive weight management program is to produce sustainable weight loss. However, for such a program to be effective, the patient must complete it. We ...
Albright Cheryl L - - 2012
Dietary supplement use is widespread among adults across races/ethnicities, yet reasons for use can vary across these groups. The Supplement Reporting (SURE) study quantified dietary supplement use and reasons for taking supplements in a multiethnic sample of adults who took at least one supplement. This study explored sociodemographic differences, including ...
Fisher Judith E - - 2012
ABSTRACT Osteoarthritis (OA) in older adults is a prevalent chronic condition associated with substantial pain and disability. Oral analgesic use is a central component of symptom management. Medication use in this population, however, is complex and must balance the need for symptom control with drug safety concerns. Our study focus ...
McLean S - - 2012
BACKGROUND: Co-morbid conditions (CMCs) are present in over half of patients with cancer over 50 years of age. As life-limiting illnesses progress, the benefits and burdens of treatments for CMCs become unclear. Relevant issues include physiological changes in advanced illness, time-to-benefit of medications, burden of medications, and psychological impact of discontinuing ...
François Bernard - - 2012
This article examines the cures recorded in Lourdes, France, between 1858, the year of the Visions, and 1976, the date of the last certified cure of the twentieth century. Initially, the records of cures were crude or nonexistent, and allegations of cures were accepted without question. A Medical Bureau was ...
Vandenplas Y - - 2012
The cost/benefit ratio of probiotics in the ambulatory treatment of acute infectious gastro-enteritis with or without a synbiotic food supplement (containing fructo-oligosaccharides and probiotic strains of Streptoccoccus thermophilus, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bifidobacterium lactis and Bifidobacterium infantis) has been studied. 111 children (median age 37 and 43 months for the ...
Rodríguez María Martín - - 2012
ABSTRACT This study examined the relationship between medical advice to engage in physical activity with type of demand required by physical activity and demographic variables. A cross-sectional study was developed, featuring a questionnaire on physicians' advice, and type of demand. The questionnaire was completed by a probability and nationwide sample ...
Ng-Mak Daisy S - - 2012
Objective: This study was conducted to characterize prescription refill patterns for triptans among European patients with new prescriptions of triptans.Background: Persistency with prescriptions of triptan monotherapy for migraine headache among newly prescribed users in European primary-care practices has not been well described.Methods: Using electronic medical databases in the UK (N = 3618), ...
Green M S - - 2012
BACKGROUND: /st>Aprepitant blocks the emetic effects of substance P. Scopolamine antagonizes muscarinic type 1 and histamine type 1 receptors. This study compares monotherapy and multimodal therapy by looking at complete response, nausea, vomiting, and rescue medication in patients at high risk for postoperative nausea and vomiting (PONV) treated with oral ...
Taber David J - - 2012
Although kidney transplant recipients at the authors' institution had a short length of stay (LOS), delayed discharges and early readmissions were common; medication use and safety were at the core of these issues. A multidisciplinary quality improvement initiative was developed that targeted eliminating these issues. The team developed key initiatives ...
Moser André A Institute of Social and Preventive Medicine (ISPM), University of Bern, Finkenhubelweg 11, CH 3012 Bern, - - 2012
Evaluation and validation of the psychometric properties of the eight-item modified Medical Outcomes Study Social Support Survey (mMOS-SS). Secondary analyses of data from three populations: Boston breast cancer study (N=660), Los Angeles breast cancer study (N=864), and Medical Outcomes Study (N=1,717). The psychometric evaluation of the eight-item mMOS-SS compared performance ...
Garland Ann F - - 2012
Studies have documented increased psychoactive medication use rates among children, but little is known about what child and/or family characteristics predict medication treatment in community-based care. This study examines the role of parent characteristics in children's medication treatment, while accounting for other potential predictors. Participants included 213 children ages 4-13 ...
Musch David C - - 2012
Three types of open-angle glaucoma (OAG)--primary, pigmentary and pseudoexfoliative--are frequently encountered. The aim of this study was to compare demographic, ocular and systemic medical information collected on people with these three OAG types at diagnosis, and determine if the OAG type affected the prognosis. Information on 607 participants of the ...
Primack Brian A BA Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, - - 2012
Although accurate health-related representations of medical situations on television can be valuable, inaccurate portrayals can engender misinformation. The purpose of this study was to compare sociodemographic and medical characteristics of patients depicted on television vs. actual United States (US) Emergency Department (ED) patients. Two independently working coders analyzed all 22 ...
Sonnett Travis E - - 2012
OBJECTIVE To explore associations between results of a rapid screening tool for cognitive impairment and individual patient characteristics in a sample of patients receiving outpatient anticoagulation therapy who were not previously diagnosed with a dementia. DESIGN Descriptive, nonexperimental, cross-sectional study. SETTING Pharmacist-managed anticoagulation clinic in Spokane, WA, from June 2006 ...
Elliott Rohan A - - 2012
Background: Aged Care Assessment Teams (ACATs) in Australia assess the care needs of frail older people. Despite being at high risk of medication-related problems (MRPs), ACAT patients do not routinely receive a comprehensive medication review. Objectives: The aims of the study were to compare three methods for facilitating a pharmacist-led ...
Neufeld Karin J - - 2012
ABSTRACT Few medical schools require a stand-alone course to develop knowledge and skills relevant to substance use disorders (SUDs). The authors successfully initiated a new course for second-year medical students that used screening, brief intervention, and referral to treatment (SBIRT) as the course foundation. The 15-hour course (39 faculty teaching ...
Wong Kam Cheong - - 2012
A male university student, 24 years of age, presented to his general practitioner because of a facial rash. He had a past history of eczema but no other significant past medical history and no allergies. He was not taking any regular medications.
Mansur Nariman - - 2012
BACKGROUND: Polypharmacy has been shown to influence outcomes in elderly patients. However, the impact of medication regimen complexity, quantified by the Medication Regimen Complexity Index (MRCI), on health outcomes after discharge of elderly patients has not been studied. OBJECTIVE: Our aim was to test the convergent, discriminant, and predictive validity ...
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