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Nauck Michael A MA Diabeteszentrum Bad Lauterberg, Kirchberg, Bad Lauterberg im Harz, Germany - - 2014
A manuscript published recently on histological changes induced in the pancreas by incretin-based medications has been widely criticized because of ill-matched groups treated with incretin-based versus non-incretin-based medications and because of methodological problems identifying glucagon-producing cells. Now a study making use of the same tissue bank is available, and does ...
Braddick Jeanne Ann - - 2013
A 56-year-old obese Caucasian woman named M.B. reported experiencing anorexia and early satiety in the prior two months. She has lost 10 pounds in two weeks. No changes had been made to her type 2 diabetes medications, she took no other medications, and her exercise habits were unchanged. M.B. made ...
Gaudet Daniel - - 2013
Abstract Background: The prevalence of severe hypertriglyceridemia (TG> 1000 mg/dl) is estimated at 150 to 400 per 100,000 individuals in North America. Severe hypertriglyceridemia in the fasting state is associated with increased acute pancreatitis risk and is a sign of chylomicronemia which reflects the accumulation in the bloodstream of chylomicrons, ...
Hart Curtis W - - 2012
This essay is concerned with the fulfillment of ordination commitments through a pastoral role in medical education and review of medical research with human subjects. Stylistically, it combines memoir with the genre known as "creative non-fiction." Its major issues have to do with the identity formation and transformation of the ...
Kim Dong Choon - - 2012
Evaluation of: Coté GA, Singh S, Bucksot LG et al. Association between volume of endoscopic retrograde cholangiopancreatography at an academic medical center and use of pancreatobiliarytherapy. Clin. Gastroenterol. Hepatol. 10(8), 920-924 (2012). Many patients have pancreatobiliary diseases involving complications and comorbidities. This study shows the trends in the use of ...
Neill Andrew - - 2012
ObjectiveApart from case reports and anecdotes, there are no published studies on the feasibility of using non-medical devices for emergency bystander cricothyroidotomy. This study evaluated the ability of non-trained junior doctors and medical students to place an emergency cricothyroidotomy on an embalmed cadaver using only a blade and a ballpoint ...
Hurren Elizabeth T - - 2012
The body trade of anatomy schools in Victorian times that underpinned the expansion of medical education has been neglected. This article examines dissection records of insane paupers, sold to repay their welfare debt to society. Each cadaver was entered in an 'Abnormalities and Deformities' dissection book. Student doctors paid fees ...
Espay A J - - 2012
To describe the phenotype of levodopa-induced "on" freezing of gait (FOG) in Parkinson disease (PD). We present a diagnostic approach to separate "on" FOG (deterioration during the "on state") from other FOG forms. Four patients with PD with suspected "on" FOG were examined in the "off state" (>12 hours after ...
Hou Jyhgong Gabriel - - 2012
BACKGROUND: For Parkinson's disease (PD) patients, adherence to a regular PD medication schedule is important in achieving optimal symptom control. There are few published studies quantifying PD medication administrations in hospitalized PD patients. METHODS: Hospitalization records for 100 veterans with idiopathic PD and admitted to our center were reviewed to ...
Jiménez Mayté Castro - - 2012
Parkinsonian tremor is among the most emblematic medical signs and is one of the cardinal manifestations of Parkinson's disease (PD). Its semiology has been extensively addressed by ancient and contemporary medical literature, but more attention has been dedicated to its medical treatment in the past than nowadays. Among the hundreds ...
Gabard Donald L - - 2012
The purpose of this descriptive study was to investigate current and future instructional practices and the most important factors influencing those practices in anatomy laboratories within medical schools and physical therapy schools. A survey instrument was developed using the Delphi method in 2008. In addition to refining the survey instrument, ...
Manning Kevin J - - 2012
Medication non-adherence is associated with chronic disease and complex medication schedules, and Parkinson's disease (PD) patients also frequently have cognitive impairments that may interfere with effective medication management. The current study quantitatively assessed the medication management skills of PD patients and probed the neurocognitive underpinnings and clinical correlates of this ...
Foreman K B - - 2012
Introduction. Dopamine-replacement medications may improve mobility while not improving responses to postural challenges and could therefore increase fall risk. The purpose of this study was to measure reactive postural responses and gait-related mobility of patients with PD during ON and OFF medication conditions. Methods. Reactive postural responses to the Pull ...
Muniz A M S - - 2011
Defined as the transient state between standing and walking, gait initiation is negatively affected in Parkinson's disease (PD), which often results in significant disability. Although deep brain stimulation (DBS) is the most common surgical procedure for PD, the long-term effects of DBS on gait initiation are not well studied. The ...
Aarts Esther E Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behavior, Kapittelweg 29, 6525 EN Nijmegen, The Netherlands. - - 2012
Dopamine has been implicated in reward-related impulsivity, but the exact relationship between dopamine, reward and impulsivity in humans remains unknown. We address this question in Parkinson's disease (PD), which is characterized by severe dopamine depletion. PD is associated primarily with motor and cognitive inflexibility, but can also be accompanied by ...
Colzato Lorenza S - - 2012
Increasing evidence suggests that the control of retrieval of episodic feature bindings is modulated by the striatal dopaminergic pathway. The present study investigated whether this may reflect a contribution from the ventral or the dorsal part of the striatum. Along the lines of the overdose hypothesis in Parkinson's disease (PD), ...
Buetow S - - 2011
What is known and objective:  Safety events indicating medication-related errors in Parkinson's disease (PD) are common but seldom studied, particularly from lay perspectives. Our objective was to study the meaning and significance to people living with PD of their experience of safety events. Methods:  Twenty qualitative interviews were conducted by ...
Nantel Julie - - 2011
AIMS AND OBJECTIVES: To assess the effect of disease severity, dopaminergic medication (med) and STN-DBS on postural stability in Parkinson's disease (PD). METHODS: Postural sway in quiet stance, and the Unified Parkinson's Disease Rating Scale (motor) (UPDRS III) were evaluated in 129 subjects in the off-med state. A subgroup of ...
Stagg P - - 2011
We present a case of severe rigidity during emergence from general anaesthesia in a 64-year-old man who had suffered from Parkinson's disease for nine years. Controversy still exists over how to optimally manage these patients perioperatively. We successfully managed his Parkinsonism with administration of crushed Sinemet" and amantadine via a ...
Yasharpour Michelle R - - 2011
Chronic idiopathic urticaria (CIU) is a common disease estimated to affect 0.1% of the population and can be very difficult to treat. Many psychotropic medications have been reported to be successful in treating refractory CIU. The purpose of this article was to discuss the pathophysiology of chronic urticaria and provide ...
Schlesinger Ilana - - 2011
OBJECTIVE:: To describe a new form of anxiety in patients with Parkinson disease (PD). METHODS:: We retrospectively reviewed 100 consecutive charts of patients with PD to identify those who did not adhere to their medication schedule owing to irrational fear of taking their medication. Information pertaining to their PD and ...
Long Timothy R - - 2011
Abstract Background: Although enrollment of women in U.S. medical schools has increased, women remain less likely to achieve senior academic rank, lead academic departments, or be appointed to national leadership positions. The purpose of this paper is to compare the gender distribution of residency program directors (PDs) with residents and ...
Cowie Dorothy - - 2011
Freezing of gait in Parkinson's disease can be difficult to study in the laboratory. Here we investigate the use of a variable-width doorway to provoke freeze behavior together with new objective methods to measure it. With this approach we compare the effects of anti-parkinsonian treatments (medications and deep-brain stimulation of ...
Hiss Jehuda - - 2011
Blunt trauma to the head and neck of a newborn during delivery process is a rare event. We report a peculiar case of decapitation of a live fetus during vacuum-assisted delivery, where excessive traction on the head of the full-term macrosomic fetus with shoulder dystocia resulted in overstretching of the ...
Korting Hans Christian - - 2011
In recent years, topically applied semi-solid formulations certified as medicals devices and not as topical drugs are increasingly used for the treatment of skin diseases. Medical devices primarily unfold their therapeutic effect by physical means, not by pharmacological, immunological or metabolic means. Intensified placing of medical devices on the dermatological ...
Castrioto Anna - - 2011
OBJECTIVE: To assess the 10-year motor outcome of deep brain stimulation of the subthalamic nucleus (STN-DBS) in patients with Parkinson disease (PD). DESIGN: Patients with PD with bilateral STN-DBS were assessed according to the Core Assessment Program for Surgical Interventional Therapies in Parkinson's Disease protocol and videotaped at baseline and ...
Rissanen Saara M - - 2011
Parkinson's disease (PD) is characterized by motor disabilities that can be alleviated reasonably with appropriate medication. However, there is a lack of objective methods for quantifying the efficacy of treatment in PD. We applied here an objective method for quantifying the effects of medication in PD using EMG and acceleration ...
Chouvarda Ioanna - - 2011
HeartCycle is an integrated project aiming to provide a disease management solution for cardiovascular disease patients, by developing technologies, algorithms to interpret data and services to facilitate the remote management of patients at home. In this paper an overview of part of the algorithmic work package, oriented at motivating the ...
Adam Jos J - - 2011
Using an anti-cue keypress task, we examined executive control in Parkinson's disease (PD) patients treated with deep brain stimulation (DBS) of the subthalamic nucleus (STN) and dopaminergic medication. Across sessions, we varied stimulation (on, off) and dopaminergic medication (on, off). Reaction time (RT) results of the PD patients and their ...
Friedman Joseph H - - 2011
ABSTRACT Hallucinations, delusions, and compulsive behaviors are frequent iatrogenic complications of the treatment of motor dysfunction in Parkinson's disease (PD). Although these have been studied, and the phenomenology described, there are few detailed descriptions of the various psychiatric problems our treated PD patients live with that allow physicians who do ...
Tormenti Matthew J - - 2011
Tyrosine hydroxylase (TH) deficiency is a rare autosomal recessive metabolic disease that results in the decreased production of catecholamines. Standard treatment relies on combinations of levodopa and carbidopa, anticholinergic agents, serotonergic agonists, and monamine oxidase B inhibitors. Unfortunately, severely affected children often require escalating doses of medication and suffer from ...
Manton John - - 2011
To the historian, the 'historical' experience of leprosy control is not simply a backdrop to contemporary patterns or problems in disease control. The control of leprosy has been enacted in different ways in localities, territories and states across the world. The specific clinical, political, and institutional choices made in leprosy ...
Kakkar Aarti - - 2011
The goal of medical treatment for Crohn's disease includes improving patients' quality of life while reducing the need for hospitalization and surgery. The current medical armamentarium includes 5-aminosalicylates, corticosteroids, immunomodulators, and biologic agents. In the past, response to treatment was measured by clinical improvement in symptoms; however, with the advent ...
Liles Anne Marie - - 2011
Because the kidney plays a large role in the absorption, distribution, metabolism, and elimination of drugs, significant medication-related problems can result from failure to properly adjust medications in patients with chronic kidney disease. It is the responsibility of all healthcare providers to be aware of necessary dose adjustments when reviewing ...
Meghani Zahra - - 2011
Recently, in increasing numbers, citizens of wealthy nations are heading to poorer countries for medical care. They are traveling to the global South as medical tourists because in their home nations either they cannot get timely medical care or they cannot afford needed treatments. This essay offers a robust, particularist ...
Shih Ludy C - - 2011
Objectives:  Deep brain stimulation (DBS) for Parkinson's disease (PD) was approved by the Food and Drug Administration in 2002 and has demonstrated clinical benefit in advanced PD. Our aim was to assess attitudes of U.S. neurologists towards the role of DBS in management of advanced PD. Materials and Methods:  We ...
Gur Arpita - - 2011
Medical curriculum does not provide required space for oral health; hence, many medical interns are unfamiliar with the oral cavity and oral health research. To study the level of awareness regarding systemic effects of periodontal disease among medical interns. A cross-sectional qualitative study recruiting medical interns from two medical institutions ...
Folland Jonathan P - - 2011
The specific neuromuscular mechanisms for compromised muscle strength with PD, and the improvement that occurs with medication, have not been clearly delineated. This study assessed knee extension and flexion strength of PD patients whilst on and off medication and examined the neural mechanisms responsible for any changes. Ten idiopathic PD ...
Marinov V V Tokuda Hospital, - - 2011
The development of modern technology and advances in medical science make possible understanding of etiology of chronic pancreatitis. From a century ago, the ethanol is connected to chronic pancreatitis. In the last decades medical science made a big footstep in understanding of so called "idiopathic pancreatitis". Factors as autoimmune disturbances, ...
Bordelon Yvette M YM Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7334, - - 2011
We assessed degree of Parkinson disease motor symptom improvement with medication among subjects enrolled in an ongoing, population-based study in Central California. The motor section of the unified Parkinson disease rating scale (UPDRS) was performed on subjects in both OFF and ON medication states, and difference between these scores was ...
Rees Geoffrey - - 2010
Medical humanities purchases its presence on the medical side of university campuses by adopting as its own the ends of medicine and medical ethics. It even justifies its presence by asserting promotion of those ends as an ethical imperative, most of all to improve the caring in medical care. As ...
Kluge Eike-Henner W - - 2010
Many countries encourage immigration, yet almost without exception they impose medical conditions on the admissibility of prospective immigrants. This paper examines the ethical defensibility of this practice. It argues that the neighbourhood principle, which states that we owe a greater duty to neighbours than to strangers, when properly understood, extends ...
Sheather Julian - - 2011
Médecins Sans Frontières (MSF) is an independent medical humanitarian organisation working in over 70 countries. It has provided medical assistance for over 35 years to populations vulnerable through conflict, disease and inadequate health systems. Medical ethics define the starting point of the relationship between medical staff and patients. The ethics of ...
Miller Franklin G - - 2010
Conventional medical ethics and the law draw a bright line distinguishing the permitted practice of withdrawing life-sustaining treatment from the forbidden practice of active euthanasia by means of a lethal injection. When clinicians justifiably withdraw life-sustaining treatment, they allow patients to die but do not cause, intend, or have moral ...
Oberman Anthony S - - 2010
A novel method of teaching military medical ethics, medical ethics and military ethics in the Israel Defense Force (IDF) Medical Corps, essential topics for all military medical personnel, is discussed. Very little time is devoted to medical ethics in medical curricula, and even less to military medical ethics. Ninety-five per ...
Górski A - - 2010
In the past years, it has become increasingly apparent that ghostwriting may erode the public trust in medical science and scientific publishing. It is estimated that approximately 10% of articles published in reputed journals are ghostwritten, and this rate may be even higher in some medical specialties. Although this practice ...
Rosenthal M Sara - - 2010
In recent years, shortages of radioisotopes that cannot be stockpiled have created a scenario in which they may be considered, periodically, a scarce medical resource. This discussion focuses on the just allocation of medical radioisotopes and presents the dominant ethical frameworks for rationing and priority setting in the patient populations ...
Phaosavasdi Sukhit - - 2010
From 2005 to 2008, the authors assessed the medical ethics of 779 medical students in the Department of Obstetrics and Gynecology at the Faculty of Medicine, Chulalongkorn University by using the Chula Method. This was conducted through a written examination asking the students to express their opinions about ethical issues. ...
Jones Sarah - - 2010
The goal of this paper is both modest and ambitious. The modest goal is to show that intercountry adoption should be considered by ethicists and healthcare providers. The more ambitious goal is to introduce the many ethical issues that intercountry adoption raises. Intercountry adoption is an alternative to medical, assisted ...
Furtmayr Holger - - 2010
The so-called Istanbul Protocol, a Manual on the Effective Investigation and Documentation of Torture and other Cruel, Inhumane or Degrading Treatment or Punishment was adopted by the United Nations soon after its completion in 1999 and since then has become an acknowledged standard for documenting cases of alleged torture and ...
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