Parenteral nutrition (PN) is one of the most complex medications administered to hospitalized and ambulatory patients. Despite the successful clinical use of PN for over 3 decades, adverse events continue to occur, resulting in serious morbidity or even mortality. There are multiple points within the PN process for errors to ...

Parenteral nutrition (PN) is a high-alert medication that contains dozens of active pharmaceutical ingredients. This complex prescription drug preparation is used in a wide variety of clinical settings for patients across the age spectrum. Despite the existence of a number of guidance documents, the drug-use process for PN suffers from ...

Analogously to Kuhn's and Hanson's understanding of observation as theory-impregnated, we try to test the hypothesis that observation and interpretation might also be value-impregnated. We use a written examination task for medical students who were asked to read and interpret a text where the authors provide arguments pro et contra ...

A useful way of reading about practice in any branch of medicine in the not too distant past is to look up the reports of the proceedings of the various sections of the British Medical Association Scientific Meeting for the year in question. So, to find out the topics which ...

This mixed-method study examines (1) the extent to which fifty adolescents receiving wraparound treatment and prescribed psychotropic medication for various psychiatric disorders report that they would continue taking medication if the decision was entirely their own (termed "medication commitment"); (2) their general subjective experiences with medication; and (3) which medication ...

Adjustments of everyday life in order to prevent disease or treat illness afflict partly unconscious preferences and cultural expectations that are often difficult to change. How should one, in medical contexts, talk with patients about everyday life in ways that might penetrate this blurred complexity, and help people find goals ...

OBJECTIVES: In this study, we aimed to assess the moderating effects of the catechol-O-methyl transferase (COMT) (ValMet) genotype on antipsychotic medication-induced changes in the cognitive performance of patients with chronic schizophrenia. METHODS: The sample consisted of 85 monozygotic and53dizygotic twin pairs, of varying concordance for schizophrenia, and healthy control twins. ...

ABSTRACT: INTRODUCTION: Lowering of hyperglycemia in the intensive care unit (ICU) is widely practiced. We investigated in which way glucose regulation, defined as mean glucose concentration during admission, is associated with ICU mortality in a medical and a surgical cohort. METHODS: Retrospective database cohort study including patients admitted between January ...

Ability to make decisions about medical treatment is compromised in significant numbers of people with neurological and psychiatric illness, and this incapacity frequently corresponds with compromised neuropsychological function. Although cognitive deficits occur often in people with multiple sclerosis (MS), no research has studied decisional capacity in that disease. The present ...

The right to die has for decades been recognised for persons in a vegetative state, but there remains controversy about ending life-sustaining medical treatment for persons in the minimally conscious state (MCS). The controversy is rooted in assumptions about the moral significance of consciousness, and the value of life for ...

Conformal Predictors (CPs) are machine learning algorithms that can provide predictions complemented with valid confidence measures. In medical diagnosis, such measures are highly desirable, as medical experts can gain additional information for each machine diagnosis. A risk assessment in each prediction can play an important role for medical decision making, ...

In cases of critical medical situations on board commercial aircraft, access to emergency medical kits can be lifesaving. Thus, this comparative study investigated acute care medication and equipment supplied in emergency medical kits on board both low-cost carriers and full-service carriers. Thirty-two European airlines (sixteen low-cost carriers and sixteen full-service-carriers) ...

BACKGROUND AND RESEARCH QUESTION: Physicians' decisions regarding the indication of medical treatment are central to the application or limitation of medical measures in advanced cancer. This qualitative study explores criteria and procedural aspects of treatment decisions with patients with cancer near the end of life from the perspective of oncologists. ...

With increasing longevity, there is an increasing need for medical professionals to face situations in which explanation for decision on life-sustaining treatment (LST) would be required. As advance decision making for LST in case of severe medical illness may be unfamiliar for most of the Chinese elders, we aim to ...

Objectives  Clinical judgment is a central element of the medical profession, essential for the performance of the doctor, and potentially generating information also for other clinicians and for scientists and health care managers. The recently renewed interest in clinical judgement is primarily engaged with its role in communication, diagnosis and ...

Patients with heart failure (HF) face an array of challenging decisions involving medications, devices, and transplants. The goal of this qualitative study was to describe patients' perceptions surrounding difficult decisions along with factors that influenced their decisions. We studied 22 patients with symptomatic HF from the University of Colorado Hospital ...

Some older individuals lack sufficient present cognitive and/or emotional ability to make and express autonomous decisions personally. In those situations, health-care providers routinely turn to available formal or informal surrogates who often must apply the best interests standard in making decisions for the incapacitated person. This article contends that defining ...

Rationale  Quality medical decision making requires that clinicians and patients incorporate the best available clinical evidence with the patients' values and preferences to develop a mutually agreed upon treatment plan. The interactive process involved in medical decision making is complex and requires patients and clinicians to use both cognitive and ...

An important part of delivering high-quality, patient-centered care is making sure patients are informed about decisions regarding their health care. The objective was to examine whether patients' perceptions about how informed they were about common medical decisions are related to their ability to answer various knowledge questions. A cross-sectional survey ...

The rise in Internet use for seeking health information raises questions about the role the Internet may play in how patients make medical decisions. To examine Internet use and perceived importance of different sources of information by patients making 9 specific medical decisions covering prescription medication initiation, cancer screening, and ...

PURPOSE: To explore physicians' attitudes toward providing directive counsel when dealing with morally controversial medical decisions, and to examine associations between physicians' opinions and their demographic and religious characteristics. METHOD: In 2008-2009, the authors mailed a survey to a stratified, random sample of 1,800 U.S. obstetrician-gynecologists. They asked participants whether, ...

This column uses the tools of normative ethics-analysis and argument-to provide a reasoned account of and to identify ethically justified responses by the psychiatrist to psychiatric inpatients' refusal of medical or surgical diagnostic work-up. There are three relevant ethical considerations when psychiatric inpatients refuse medical or surgical diagnostic tests: balancing ...

To make informed decisions, patients must have adequate knowledge of key decision-relevant facts. To determine adults' knowledge about information relevant to common types of medication, screening, or surgery decisions they recently made. National sample of US adults identified by random-digit dialing. Cross-sectional survey conducted between November 2006 and May 2007. ...

ERNST J., WEISSFLOG, G., BRÄHLER E., NIEDERWIESER D., KÖRNER A. & SCHRÖDER C. (2010) European Journal of Cancer Care Participation of haemato-oncological patients in medical decision making and their confidence in decisions Increasingly more clinical care and research acknowledge the patients' interest in participating in medical decision making. However, for ...

There are effective medications available for the treatment of rheumatoid arthritis (RA); yet, medication adherence remains a problem. In this study, grounded theory methodology was used to investigate the decision-making process used by 30 women with RA when deciding to participate in an evidence-based treatment regimen for this disease. From ...

We tested the usability of a patient-directed decision aid (DA), intended for patients with early stage papillary thyroid carcinoma (PTC) deciding to accept or reject adjuvant radioactive iodine (RAI) treatment. This decision is complicated by uncertainty of the medical evidence relating to potential treatment benefits. The DA was tested by ...

This paper focuses on psychiatric medication experiences among a sample of North American university students to explore a new cultural and social landscape of medication 'compliance.' In this landscape, patients assume significant personal decision-making power in terms of dosages, when to discontinue use and even what medications to take. Patients ...

Many analyses of medical treatments entail the aggregation of health outcomes over patients and over time. This study assessed the extent to which voters, medical administrators, and physicians consider such aggregation to be appropriate. In addition, the study assessed whether this perceived fungibility of outcomes moderates the difference between treatment ...

The task of medical diagnosis is a complex one, considering the level vagueness and uncertainty management, especially when the disease has multiple symptoms. A number of researchers have utilized the fuzzy-analytic hierarchy process (fuzzy-AHP) methodology in handling imprecise data in medical diagnosis and therapy. The fuzzy logic is able to ...

Assistance for patients faced with medical decisions has largely focussed on the clarification of information and personal values. Our aim is to draw on the decision research describing the role of emotion in combination with health behaviour models to provide a framework for conceptualizing patient decisions. A review of the ...

OBJECTIVE: This paper reports on a brief survey of clinicians' judgements when making treatment decisions in the context of diagnostic uncertainty. Specifically, attitudes and opinions were sought from practising consultant psychiatrists regarding two key areas of clinical decision-making in first episode psychosis (FEP), namely, when to initiate medication and, how ...

"Decision making" in many fields of human activity is often carried out in typically stressful situations and in a brief space of time. The basis of decision making has been studied under different aspects, taking mainly into account the uncertainty underlying the decision, and all the risks that every decision ...

BACKGROUND: In recent years, there has been significant interest and investment in conducting comparative effectiveness research (CER) of medical treatments to improve the quality of care and reduce costs. The Agency for Healthcare Research and Quality (AHRQ) has been leading this effort and has invested a significant amount of resources ...

Decision-making in clinical practice is complex and getting more complex. There are a large range of alternative actions possible, all with different consequences and trade-offs. The complexity of medical decision-making is best illustrated using a clinical scenario.

Current models of the medical consultation emphasize shared decision-making (SDM), whereby the expertise of both the doctor and the patient are recognised and seen to equally contribute to the consultation. The evidence regarding the desirability and effectiveness of the SDM approach is often conflicting. It is proposed that the conflicts ...

OBJECTIVE: To evaluate the modes of death and treatment offered in the last 24 h of life to patients dying in 10 Brazilian intensive care units (ICUs) over a period of 2 years. DESIGN AND SETTING: Cross-sectional, multicentre, retrospective study based on medical chart review. The medical records of all ...

The law recognises the right of a competent adult to refuse medical treatment even if this will lead to death. Guardianship and other legislation also facilitates the making of decisions to withhold or withdraw life-sustaining treatment in certain circumstances. Despite this apparent endorsement that such decisions can be lawful, doubts ...

It is sometimes necessary for courts to appoint guardians for adult, incapacitated patients. There are few data describing how medical decisions are made for such patients before and during the guardianship process. To describe the process of medical decision-making for incapacitated, hospitalized adults for whom court-appointed guardians are requested. Retrospective, ...

The potential of computer based tools to assist physicians in medical decision making, was envisaged five decades ago. Apart from factors like usability, integration with work-flow and natural language processing, lack of decision accuracy of the tools has hindered their utility. Hence, research to develop accurate algorithms for medical decision ...

Patient involvement is required before patients' preferences can be reflected in the medical care they receive. Furthermore, patients are a vital link between physicians' assessments of patients' needs and actual implementation of appropriate care. Yet no study has specifically examined how and when a representative sample of patients considered, discussed, ...

Most clinicians take for granted a simple, reductionist understanding of medical knowledge that is at odds with how they actually practice medicine; routine medical decisions incorporate more complicated kinds of information than most standard accounts of medical reasoning suggest. A better understanding of the structure and function of knowledge in ...

The primary goal of evidence-based medicine (EBM) has been to change the way clinicians make decisions. But EBM has inappropriately privileged the results of clinical research for medical decision making and has undermined the importance of other kinds of medical knowledge, pathophysiologic understanding and clinical experience, to clinical practice. Here, ...

Evidence from well-designed clinical trials may guide clinicians, reduce regional variation, and lead to improved outcomes. Many physicians choose to ignore evidence-based practice guidelines. Using unproven therapies outside of a randomized trial slows recruitment in clinical trials that could yield information on clinical and economic efficacy. Using acute stroke therapy ...

BACKGROUND: The Current Procedural Terminology (CPT) coding system for office visits, which has been in use since 1995, has not been well studied, but it is generally agreed that the system contains much room for error. In fact, the available literature suggests that only slightly more than half of physicians ...

Despite the wide and daunting array of cross-cultural obstacles that the formulation of a global policy on advance directives will clearly pose, the need is equally evident. Specifically, the expansion of medical services driven by medical tourism, just to name one important example, makes this issue urgently relevant. While ensuring ...

Ear, nose and throat conditions make up a large amount of a Medical Officer's clinical workload. The examples given here illustrate some principles that should be employed when dealing with such problems.

This paper explains the role of Bayes Theorem and Bayesian networks arising in a medical negligence case brought by a patient who suffered a stroke as a result of an invasive diagnostic test. The claim of negligence was based on the premise that an alternative (non-invasive) test should have been ...

The evaluation of medical decision-making capacity and provision of emergency treatment in the acute care setting may present a significant challenge for both physicians-in-training and attending physicians. Although absolutely essential to the proper care of patients, recalling criteria for decision-making capacity may prove cumbersome during a medical emergency. Likewise, the ...

INTRODUCTION: Toxicological studies of accident pilots frequently find the presence of over-the-counter (OTC) drugs. While many of these drugs are approved for use while flying, others are not. To better understand how pilots come to use unapproved OTC drugs, this study explored psychological and behavioral factors that might influence pilots' ...

Legislation governing advance directives has been enacted in six Australian jurisdictions. As evidenced by parliamentary debates, the goal of enacting legislation was to enshrine the common law and to remove any doubt about whether a competent individual was entitled to complete an advance directive that refused life-sustaining medical treatment. The ...