Anticoagulant drugs are among the most common medications that cause adverse drug events (ADEs) in hospitalized patients. We performed a 5-year retrospective study at Brigham and Women's Hospital to determine clinical characteristics, types, root causes, and outcomes of anticoagulant-associated ADEs. We reviewed all inpatient anticoagulant-associated ADEs, including adverse drug reactions ...

The European Conformity (CE) marking grants early market introduction to innovative high risk medical devices based on safety and device performance only, without any requirement to demonstrate clinical efficacy or effectiveness. Hence healthcare providers, patients and payers are informed neither about the added clinical value compared to an existing medical ...

FlyRNAi (http://www.flyrnai.org), the database and website of the Drosophila RNAi Screening Center (DRSC) at Harvard Medical School, serves a dual role, tracking both production of reagents for RNA interference (RNAi) screening in Drosophila cells and RNAi screen results. The database and website is used as a platform for community availability ...

ObjectiveTo evaluate the impact of a real-time computerized decision support tool in the emergency department that guides medication dosing for the elderly on physician ordering behavior and on adverse drug events (ADEs).DesignA prospective controlled trial was conducted over 26 weeks. The status of the decision support tool alternated OFF (7/17/06-8/29/06), ...

Hospitalised patients commonly experience adverse drug events (ADEs) and medication errors. Runciman reported that ADEs in hospitals account for 20% of reported adverse events and contribute to 27% of deaths where death followed an adverse event. Hughes recommends multidisciplinary hospital drug committees to assess performance and raise standards. The new ...

In the late 1990s, the World Health Organization (WHO) created the Medical Eligibility Criteria for Contraceptive Use (MEC), which provide evidence-based recommendations for safe and effective contraception in women with medical problems. The WHO MEC incorporate the best available evidence, are periodically updated, and are designed to be modified for ...

ABSTRACT: BACKGROUND: Medication errors (ME) are an important problem in all hospitalized populations, especially in intensive care unit (ICU). The aim of the study was to determine incidence, type and consequences of ME. Materials and methods: Prospective observational cohort study during six weeks in a Moroccan ICU. Were included all ...

OBJECTIVE: to examine the effect of medications with anticholinergic effects on cognitive impairment and deterioration in Alzheimer's dementia (AD). METHODS: cognitive function was measured at baseline and at 6- and 18-month follow-up using the Mini-Mental State Exam (MMSE), the Severe Impairment Battery (SIB) and the Alzheimer's Disease Assessment Battery, Cognitive ...

PubMed interface re-engineering has moved further steps with the latest changes in the MeSH - Medical Subject Headings database and in the MyNCBI homepage. Aim of this contribution is to present the most relevant added feature in order to improve your query efficiency.

This study examined the association between hypertension and AD by using a quantitative meta-analysis of longitudinal studies. EMBASE and MEDLINE were searched for articles published up to February 2011. All studies that examined the association of hypertension or antihypertensive medication use with the onset of AD were included. Pooled relative ...

High fractional concentrations of inspired oxygen (FiO(2)) delivered over prolonged periods produce characteristic histological changes in the lungs and airway of exposed animals. Modern medical anaesthetic machines are adapted to deliver medical air (FiO(2)=0.21) for the purpose of reducing FiO(2); anaesthetic machines designed for the veterinary market have not been ...

This study describes coping strategies that patients with heart failure (HF) use to manage adverse drug events (ADEs). The included coping strategies were social support seeking, information seeking, non-adherence and taking alleviating medication. The role of beliefs about medication and ADE perceptions in explaining these coping strategies was assessed using ...

In this study, the author analyzed the relevance of anatomical eponyms for medical education by researching 453 anatomical eponyms and their corresponding English or Latin terms in the Medline database. The number of hits in the database ranged from 0 to 34,490 per eponym (median 11). Almost a quarter (110) ...

BACKGROUND: Identifying patients with heart failure (HF) who are at risk of experiencing symptomatic adverse drug events (ADEs) is important for improving patient care and quality of life. Several demographic and clinical variables have been identified as potential risk factors for ADEs but limited knowledge is available on the impact ...

Objectives: Adverse drug events (ADEs) occur more frequently in pediatric patients than adults. ADEs frequently cause serious harm to children and increase the cost of care. The purpose of this study was to decrease ADEs by targeting the entire medication-delivery system for all high-risk medications. Methods: Thirteen freestanding children's hospitals ...

The objective of this study was to evaluate patients' real-world experiences with desonide hydrogel for the treatment of mild to moderate atopic dermatitis (AD). Physicians who participated in this patient-experience program identified eligible participants (age range, < 3 months to 91 years) for treatment with desonide hydrogel 0.05%. The medication ...

Objectives To determine what information can be helpful in prioritizing and presenting medication alerts according to the context of the clinical situation. To assess the usefulness of different ways of delivering medication alerts to the user. Design An international Delphi study with two quantitative rounds. 69 researchers with expertise in ...

Topical corticosteroids have been the mainstay of treatment for atopic dermatitis (AD) over the last decade, especially in the setting of acute flares. However, heavy and prolonged use of topical corticosteroid is undesirable as it is associated with side effects such as, skin atrophy, telangiectasia, striae, steroid-induced dermatoses, rosacea, acne ...

In its 2006 report "Preventing Medication Errors," the Institute of Medicine (IOM) estimated that more than 1.5 million preventable adverse drug events (ADEs) occur annually in the United States. Many organizations, including the IOM, the Institute for Safe Medication Practices, the US Food and Drug Administration, and the Leap Frog ...

The Liber medicine orinalibus (codex 69 Montecassino) of Hermogenes is the first known manuscript to have a Latin translation from the original Greek work of Magnus of Emesa (or Nisibis). The particular text here translated, from the so-called Commentatio, mentions direct transliteration of Greek concepts such as chyma and hypostasis, ...

As the first step of UCB banking, UCB collection has an important role in banking procedures. The aim of this study was to reveal the current status of UCB collection and discuss the management of the UCB bank. We conducted a questionnaire survey at medical centers collecting UCB, followed by ...

ABSTRACTThis study examines the importance of variables from the Theory of Planned Behaviour (i.e.,attitudes toward behaviour, subjective norms, and perceived control) for the prediction of consumption of anxiolytic and sedative-hypnotic (ASH) medications in a sample of older persons, aged 69 years on average, 62 consumers and 92 non-consumers. A favourable ...

Medical historiography deals with the concepts, theories, and approaches adopted in the reconstruction and discussion of the history of medicine. The expression has changed through time and according to different scholars and contexts, and it largely depends on the general standpoint from which the medicine of the past is examined. ...

In patients with Parkinson's disease with higher prevalence than in current population there appear pathological behaviours characterized by compulsion, repetitiveness and impulsivity, which are connected with material profit or pleasurable experience. They are, in particular, pathological gambling, hypersexuality, compulsive shopping and compulsive eating (in the literature they are collectively referred ...

As the medical education community celebrates the 100th anniversary of the seminal Flexner Report, medical education is once again experiencing significant pressure to transform. Multiple reports from many of medicine's specialties and external stakeholders highlight the inadequacies of current training models to prepare a physician workforce to meet the needs ...

To describe the economic burden of allergic rhinitis treatment and current guidelines for treatment. Review articles and original research were retrieved from MEDLINE, OVID, PubMed (1950-November 2009), personal files of articles, and bibliographies of located articles that addressed the topic of interest. Articles were selected for their relevance to the ...

Historical progression and the development of current teaching hospitals, medical schools and biomedical research originated from the people of many civilizations and cultures. Greeks, Indians, Syriacs, Persians and Jews, assembled first in Gondi-Shapur during the Sasanian empire in Persia, and later in Baghdad during the Golden Age of Islam, ushering ...

Twentieth-century medical education constructed medicine as biomedical science. Although bioscientific knowledge has brought large benefits to clinical practice, many have questioned the appropriateness of its domination of the medical curriculum. As the content of that curriculum is itself a historically mediated social construct, it can be changed to fit current ...

We describe a female patient with a giant venous thrombus that exhibited transcutaneous elimination. This thrombus elimination is probably a unique case in the medical literature.

The snake has served as a medical emblem for more than 2400 years, since its association with the ancient Greek god of medicine and healing, Asclepius, in the 4th century BC. Its symbolic background can be traced further back to the worship of gods of earth's blossom in ancient Egypt ...

Adverse Drug Events (ADEs) are injuries due to medication management rather than the underlying condition of the patient. They endanger the patients and most of them could be avoided and prevented. The detection of ADEs usually relies on spontaneous reporting or medical chart reviews. The first objective of the PSIP ...

Indian traditional medicine, Ayurveda has a great history. Researchers in India have tried to corroborate ancient wisdom with the modern scientific practices. Tailabindu pariksha is a diagnostic tool of urine examination developed by the medieval Ayurvedic scholars, and also throws a light on the prognosis of the disease condition. This ...

To assess the impact of administration errors when transcribing treatments to nurses' administration forms, and to estimate the impact of electronically assisted prescription (EAP) in minimising these errors. A prospective, observational study in hospitalised patients. In a representative sample changes in treatment in the 24 h before the examination are ...

The development and implementation of a new pharmacy practice model at an academic medical center are described. Before the model change, decentralized pharmacists responsible for order entry and verification and clinical specialists were both present on the care units. Staff pharmacists were responsible for medication distribution and sterile product preparation. ...

Changes in medical practice and a greater emphasis on lifelong learning are prompting a closer look at the efficacy of continuing medical education (CME). This article outlines the shortcomings of the current CME system, describes findings from two recent reports about its status, and presents recommendations for a new system ...

The next time you have a drill for your department, you might consider enlisting some local talent to play the patients. Valley Medical Center in Renton, WA, used actors from the community to prepare ED staff for a recent move into new facilities, and the ED leaders say it made ...

Healthcare workers need to be protected during a severe influenza outbreak; therefore, we evaluated 4 different antiviral strategies: (1) using antiviral medication for outbreak prophylaxis of all hospital employees; (2) using antiviral medication for postexposure prophylaxis (PEP) or treatment of all hospital employees; (3) using a combination of antiviral medication ...

BACKGROUND: While family presence during resuscitation has been researched extensively in the international and especially American medical literature, in Israel this subject has rarely been researched. Because such policies have become common practice in many countries, it is important to investigate the attitudes of health care staff in Israeli emergency ...

In response to feedback from the medical community, The Joint Commission has revised its medical staff standard. If the medical staff wants to have the associated details of all elements in the bylaws they can, but they can also reference them in rules and regulations or policies and procedures. The ...

Good feedback is rare. That is because it takes considerable time, effort, skill, and know-how to be able to provide and use feedback effectively. This article explores why feedback is a frequently misused and underused practice management tool. It describes the tenets of useful feedback and five common medical practice ...

If every doctor is a teacher, then every doctor should be an examiner too. Assessment has a huge impact on learning; more so than most realise. Whilst there have been seemingly endless changes to current assessment strategies, there are some fundamental tenets to fair assessment that have changed little in ...

A hospital uses a medical staff dashboard to promote quality improvement.

This document is the second of a series of policy statements being issued by the Asia-Oceania Federation of Organizations for Medical Physics (AFOMP). The document was developed by the AFOMP Professional Development Committee (PDC) and was released by the AFOMP Council in 2009. The main purpose of the document is ...

Background: Some psychiatric patients are presented as hopeless, burned out, and devoid of social graces. Staff of mental health centers and hospitals are not encouraged to view these people differently. A narrative perspective allows anyone to emerge as a richly complex human being.Method: A course presented students with the opportunity ...

This article outlines current safe harbors in the law for healthcare practitioners who work in a disaster setting. It reviews available legal protection in crisis situations with respect to the Emergency Medical Treatment and Labor Act (EMTALA), criminal liability, and licensure.

The article examines the significance of the integration of medical clowns as an intervention strategy with adult outpatients suffering from chronic illnesses. The study is based on content analysis of the documentation of the work of two medical clowns over two years. The dominant theme involves the definition of the ...

The Hospital Inpatient Enquiry (HIPE) system is currently used as a principle source of national data on discharges from acute hospitals. The Casemix Programme is used to calculate funding for patient care (HIPE activity and Specialty Costs Returns). Th coding is usually undertaken by clerical personnel. We were concerned that ...

BACKGROUND: Professional staff engaged in medical education research was important for enhancing the quality of medical education. AIM: To look at the current condition of professional staff in medical education research units in China. METHODS: A total of 46 related-to-insiders in 46 medical schools completed a questionnaire including the affiliation ...

Established in 1902, the West African Medical Staff (WAMS) brought together the six medical departments of British West Africa. Its formation also followed the foundation of schools of tropical medicine in London and Liverpool. While the 'white' dominions were at the centre of Joseph Chamberlain's ambitions of erecting a system ...

PURPOSE: To explore the perceptions of medical staff on the rehabilitation of spinal cord injured individuals, who became disabled from street violence. METHOD: A total of 16 medical staff members from two rehabilitation hospitals were interviewed, using a semi-structured interview. The interview recorded demographic information about the staff and probed ...