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Lamichhane Dronacharya - - 2014
Stroke is becoming a major cause of morbidity and mortality in the developing world while the trend is actually downward in the developed nations. This is mostly because of the better recognition, treatment options and secondary prevention in addition to changes in lifestyles. There have been significant developments in the ...
Quek Ruben G W RG Statistics and Evaluation Center, Intramural Research Department, American Cancer Society and Department of Health Policy and Management, Emory University, Atlanta, Georgia. Electronic address: - - 2014
Physician characteristics and changes in drug reimbursement rates have been shown to influence practice patterns regardless of clinical guidelines, patient, clinical, or sociodemographic factors. We concurrently examined the association between urologists׳ characteristics and non-evidence-based use of primary medical androgen deprivation therapy (ADT) for clinically localized patients with prostate cancer, before ...
Gies Inge I I Gies, Pediatric Endocrinology, UZ Brussel, Brussels, - - 2014
Klinefelter Syndrome (KS) is the most common sex chromosome disorder in males. Key findings in older adolescents and young men are small testes with variable hypo-androgenism but almost universal azoospermia, most frequently in combination with a history of learning difficulties and behavior problems. KS males may come to medical attention ...
Rahnema Cyrus D CD University of Tennessee Graduate School of Medicine, Knoxville, - - 2014
To develop an understanding of hypogonadal men with a history of anabolic-androgenic steroid (AAS) use and to outline recommendations for management. Review of published literature and expert opinions. Intended as a meta-analysis, but no quality studies met the inclusion criteria. Not applicable. Men seeking treatment for symptomatic hypogonadism who have ...
Banka Nusrat - - 2013
Androgenetic alopecia is a common cause of hair loss in both men and women. The exact pathogenesis of androgenetic alopecia is not well understood. As the name implies, the role of androgens and genetic susceptibility predisposes to pattern hair loss due to gradual conversion of terminal hair into vellus hair. ...
Hansson Mats G - - 2012
BACKGROUND: Medical registries serve patients as beneficiaries of quality standards and new treatment opportunities. However, it has been argued that registries threaten patient privacy interests and should therefore be more strictly regulated. METHODS AND RESULTS: With the European Treatment and Outcome Study for Chronic Myeloid Leukemia as a concrete example ...
Johnson Kimberly J - - 2012
Although a few previous studies have reported positive associations between adult myeloid leukemia and a history of certain medical conditions, the etiology of most cases remains largely unknown. Our purpose was to examine associations between certain medical conditions and adult myeloid leukemia. Using logistic regression, we evaluated associations between 16 ...
Levy Emmanuelle - - 2012
Objective: Poor adherence to medication is a major determinant of relapse following treatment of first-episode psychosis (FEP). However, medication-adherent patients also relapse. We examined what factors influence the risk of relapse after controlling for adherence. Method: We selected a sample of fully adherent patients (n = 65) who had achieved ...
De Angelis C - - 2012
Background. The event-free survival for pediatric leukemia in low-income Countries is much lower than in high-income countries. Late diagnosis, which is regarded as a contributing factor, may be due to "parental" or "medical" delay. Procedures. The present study analyses determinants of lag time from first symptoms to diagnosis of leukemia, ...
Beck Eva-Marina - - 2012
ABSTRACT: Attitudes toward medication are important predictors of medication adherence in schizophrenia. However, monitoring their strength and influence in clinical settings is challenged by the absence of assessments separating them from adherence and subjective response and distinguishing between attitudes toward pharmacotherapy in general and antipsychotic medications. This study examined the ...
Grimm O O Department of Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim/University Heidelberg, Mannheim, - - 2012
The occurrence of weight gain in schizophrenia (SZ) has profound clinical impact and interacts with antipsychotic medication, life style and disease severity. The functional neuroanatomy underlying altered nutritional behavior is unraveled, but dysregulated reward anticipation might be one of the involved neuronal mechanisms. The striatum, a core region of the ...
Krakowski Menahem I - - 2011
OBJECTIVE: Despite extensive experience with antipsychotic medications, we have limited capacity to predict which patients will benefit from which medications and for what symptoms. Such prediction is of particular importance for the proper treatment of violence. Our goal was to determine whether executive function predicts outcome of treatment for aggressive ...
Van Strater Annelies C P - - 2011
St John's wort (Hypericum perforatum) is notorious for its ability to induce the enzymes of the P450 system. Especially, it induces CYP1A2 and CYP3A4, enzymes that are closely involved in the metabolism of clozapine. We present a patient with schizophrenia, who was stable on a fixed dose with stable plasma ...
Adelufosi Adegoke Oloruntoba - - 2011
OBJECTIVE: The aim of this study was to examine medication adherence among outpatients with schizophrenia in relation to their subjective quality of life and other sociodemographic, clinical and service related factors. METHODS: Three hundred and thirteen consecutive outpatient clinic attendees with a Diagnostic and Statistical Manual of Mental Disorders Fourth ...
Pai N B - - 2011
Pai NB, Vella SC. Reason for clozapine cessation. Objective:  Approximately 30% of individuals diagnosed with schizophrenia suffer from treatment-resistant or refractory schizophrenia. The gold standard for treatment of refractory schizophrenia is clozapine. However, a significant number of patients cease clozapine therapy; therefore this study explores patient's motives for cessation. Method:  ...
Moilanen J - - 2011
OBJECTIVE: To estimate the prevalence of non-medicated subjects having schizophrenia spectrum disorder and to study how they differ from medicated subjects in terms of sociodemographic and illness-related variables. We also aim to find the predictors for successful antipsychotic withdrawal. METHODS: Data of 70 subjects with schizophrenic psychoses (mean duration of ...
Serafini G - - 2011
ACCESSIBLE SUMMARY: •  Genetic explanation of schizophrenia was frequently associated with stigmatizing attitudes. •  Medical students and doctors expressed higher levels of perceived stigmatization than other groups of subsects. •  Participants perception of other people stigmatizing attitudes was associated with genetic explanation of schizophrenia. ABSTRACT: Stigmatization of schizophrenia is widespread ...
Brnabic A J M - - 2011
Aims:  This study compared all-cause medication discontinuation (any switch, augmentation or medication discontinuation) in matched cohorts of patients with schizophrenia who were initiated on depot or oral antipsychotics. Other objectives included between-group comparisons of resource use, and clinical and functional outcomes. Methods:  This post hoc analysis of a one-year, multicentre, ...
Kane John M - - 2011
Nonadherence to antipsychotic medications is an enormous challenge for clinicians and patients in the treatment of schizophrenia. Nonadherence and partial adherence are associated with high rates of relapse, rehospitalization, and suicide attempts. Assessing adherence can be difficult because patients are likely to overestimate their medication adherence and may not report ...
Meszaros Zsuzsa Szombathyne ZS Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY 13210, United States. - - 2011
Schizophrenia and alcohol dependence (AD) are both major risk factors for a variety of medical problems, yet little is known about the medical status of patients in whom both conditions coexist. The objectives of this study are to assess accuracy of self-reported medical problems and to compare the accuracy reports ...
Misdrahi David - - 2011
Background: Poor adherence is one of the leading problems affecting the effectiveness of treatment in schizophrenia. It is an identified factor for relapse and hospitalizations with major social and economic consequences. Various determinants of poor adherence have been identified but few studies investigate the role of therapeutic alliance on medication ...
Beck Eva-Marina - - 2011
BACKGROUND: Despite the fact that medication adherence is among the most important health related behaviors in relapse prevention and recovery in schizophrenia, it is often not sufficiently endorsed by patients. Poor insight and negative attitudes towards medication are risk factors for non-adherence. Their relationship and the influence of more general ...
Tranulis Constantin - - 2011
Objective: Discontinuation of antipsychotic medication is a pervasive clinical problem in the treatment of patients suffering from psychosis. The aim of this study was to complement a largely quantitative body of research by focusing on patients' perspectives on the topic. Methods: In-depth semistructured interviews were conducted with 20 persons who ...
Magliano Lorenza - - 2011
PURPOSE: Negative attitudes toward mental illness among medical professionals can influence the quality of medical care they provide. The authors examined the impact of causal explanations and diagnostic labeling on medical students' views of schizophrenia. METHOD: Medical students in their fifth and sixth years at the Second University of Naples ...
Wong Daniel Fu Keung - - 2011
Objective: The study reported in this paper was aimed at developing understanding of schizophrenia-related knowledge and preferences surrounding professional help, medication, and treatment methods among Chinese living in Shanghai, China. Method: A multi-stage cluster sampling method in which participants were taken from six of the 20 districts in Shanghai was ...
Walterfang Mark - - 2011
Although historically gray matter changes have been the focus of neuropathological and neuroradiological studies in schizophrenia, in recent years an increasing body of research has implicated white matter structures and its constituent components (axons, their myelin sheaths and supporting oligodendrocytes). This article summarizes this body of literature, examining neuropathological, neurogenetic ...
Puri Basant K - - 2011
Evaluation of: Ho BC, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. Arch. Gen. Psychiatry 68(2), 128-137 (2011). Schizophrenia is associated with progressive brain changes, including progressive brain tissue decreases and lateral ventricular volume increases for up to ...
Farley Joel F - - 2011
Objective: The purpose of this study was to examine whether medication refill behavior varies by the number of prescribers of antipsychotic medication a patient has. Methods: A total of 7,868 patients with schizophrenia were identified from North Carolina Medicaid records for the period 2001-2003. Medication switching and adherence outcomes in ...
Swerdlow Neal R NR School of Medicine, University of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093-0804, United States. - - 2011
New findings are rapidly revealing an increasingly detailed image of neural- and molecular-level dysfunction in schizophrenia, distributed throughout interconnected cortico-striato-pallido-thalamic circuitry. Some disturbances appear to reflect failures of early brain maturation, that become codified into dysfunctional circuit properties, resulting in a substantial loss of, or failure to develop, both cells ...
Lam Annie Y - - 2011
To assess pillbox fill accuracy and cognition among community-dwelling older adults. A descriptive, cross-sectional study. Retail pharmacy. Convenience sample of English-speaking adults older than 60 years of age without dementia, taking more than four medications, and naive to Mediset use. In face-to-face interviews, subjects provided demographic, medical, and medication information, ...
Demler Tammie Lee TL Buffalo Psychiatric Center, Buffalo, New York, - - 2011
Clozapine is an atypical antipsychotic agent used for refractory schizophrenia. It has a relatively low affinity for D2 receptors and thus is associated with a lower incidence of extrapyramidal side effects when compared with typical antipsychotics. Clozapine as monotherapy can induce a rare, but serious, blood dyscrasia called agranulocytosis; however, ...
Casey David A - - 2011
Schizophrenia is a devastating and common psychiatric disorder which is associated with a high degree of medical morbidity and reduced life span in addition to psychosis. In this article, these problems will be discussed in the context of schizophrenia and aging. The recent literature was reviewed using Pubmed, Medline, and ...
Mayer G - - 2011
Clinical Dilemma: 'An 18-year-old patient, who has been suffering from a prolonged psychotic state, is hospitalized for the first time in his life in our department. We diagnose his condition as schizophrenia, and start anti-psychotic medication and supportive psychotherapy. His parents join the psycho-educational group for families in our department. ...
Bola John J Department of Applied Social Studies, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong SAR, Hong - - 2011
Long-term treatment with antipsychotic medications in early episode schizophrenia spectrum disorders is common, but both short and long-term effects on the illness are unclear. There have been numerous suggestions that people with early episodes of schizophrenia appear to respond differently than those with multiple prior episodes. The number of episodes ...
Kwiatkowski Mercedes - - 2011
Ileus can result from the combined activity of antipsychotic and anticholinergic medications. Despite frequent use, case reports in the literature are sparse. We present a patient who developed a paralytic ileus requiring extended hospitalization. Providers should minimize antipsychotic and concurrent anticholinergic medications, consider prophylactic bowel regimens and monitor for constipation.
Rungruangsiripan Malatee - - 2011
The purpose of this cross-sectional research study was to examine factors affecting medication adherence in Thai individuals with schizophrenia. The Common-Sense Model of Illness Representation was used to guide the study. Two hundred twenty-five subjects met the inclusion criteria and were interviewed. Variables of interest focused on experience of medication ...
Heuser Cara C - - 2010
Most data regarding conditions associated with or contributing to stillbirth are derived from fetal death certificates. Our purposes were to compare stillbirth data recorded in vital statistics with those in the medical record and to investigate whether diagnostic evaluations differed in tertiary care and community hospitals. In this cross-sectional study, ...
Quantin Catherine - - 2011
The purpose of our multidisciplinary study was to define a pragmatic and secure alternative to the creation of a national centralised medical record which could gather together the different parts of the medical record of a patient scattered in the different hospitals where he was hospitalised without any risk of ...
- - 2010
Among those standards The Joint Commission reports offer the most difficult compliance challenges for hospitals, the three that have the greatest impact on EDs involve complete lab records, complete and accurate patient records, and egress. Install an electronic medical record, and verify that results have been reviewed. If you use ...
Aberdeen John - - 2010
Medical records must often be stripped of patient identifiers, or de-identified, before being shared. De-identification by humans is time-consuming, and existing software is limited in its generality. The open source MITRE Identification Scrubber Toolkit (MIST) provides an environment to support rapid tailoring of automated de-identification to different document types, using ...
Singh J A JA Birmingham VA Medical Center, University of Alabama, Birmingham, AL, USA. - - 2010
To examine the validity of International Classification of Diseases-Ninth Revision (ICD-9) and Current Procedural Terminology (CPT) codes for knee replacement and hip replacement in Veterans Affairs (VA) databases. From a cohort of veterans who received health care at Minneapolis VA Medical Center and/or affiliated medical facilities, we obtained four random ...
Alexander Emily L R - - 2011
The University of British Columbia Hospital Clinic for Alzheimer Disease and Related Disorders (UBCH-CARD) invests significant effort to obtain medical records for the confirmation of patient-reported family histories of dementia. The effectiveness of requesting these records was assessed through a review of the 275 requests made by UBCH-CARD genetic counselors ...
Charlton Rachel A - - 2010
Postmarketing teratogen surveillance is essential and requires a data source that can reliably capture a wide range of congenital malformations. The UK General Practice Research Database (GPRD) may have the potential to be used for this kind of surveillance. To assess the extent to which this database can be used ...
Ajami Sima - - 2012
Medical Records Department (MRD) is an important unit for evaluating and planning of care services. The goal of this study is evaluating the performance of the Medical Records Departments (MRDs) of the selected hospitals in Isfahan, Iran by using Analytical Hierarchy Process (AHP). This was an analytic of cross-sectional study ...
Wekre Liv Johanne - - 2010
The objective of this study was to investigate whether implementation of multidose drug dispensing (MDD) for elderly outpatients is associated with a change in the number of discrepancies in the medication record at the general practitioners (GPs) and at the community home-care services. A controlled follow-up study with paired design ...
Szatkowski Lisa - - 2010
the process of registering new patients in primary care provides an ideal opportunity to assess their smoking status systematically and record this in electronic medical records; this identification then allows smokers to be targeted with effective cessation interventions. to use a dataset of electronic primary care medical records to assess ...
Schaum Kathleen D - - 2010
Before providers order pressure-reducing support surfaces for Medicare beneficiaries, they should obtain and read (1) the LCD and attached articles that pertain to their DME MAC jurisdiction and (2) the Special Edition SE1014 educational article released by the Medicare Learning Network of CMS. Providers should be sure that the patient's ...
Uzuner Ozlem - - 2010
We describe semantic relation (SR) classification on medical discharge summaries. We focus on relations targeted to the creation of problem-oriented records. Thus, we define relations that involve the medical problems of patients. We represent patients' medical problems with their diseases and symptoms. We study the relations of patients' problems with ...
Lie D A - - 2010
Presents a 55-word story about a missed diagnosis of labor by a medical student. (PsycINFO Database Record (c) 2010 APA, all rights reserved).
Fisher Deborah A - - 2010
BACKGROUND: Administrative procedure code data can estimate colonoscopy utilization; however, determining colonoscopy indication is more difficult as procedure codes do not inherently reflect the purpose (screening, surveillance, diagnosis) of the colonoscopy. AIM: To improve the reported sensitivity (70%) and specificity (72%) of a published algorithm for identifying screening colonoscopies using ...
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