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Shrivastav Rahul R Communicative Sci. and Disord., Michigan State Univ., East Lansing, - - 2014
Speech production in noise elicits the Lombard effect, characterized by an increase in vocal effort. In talkers with Parkinson's disease (PD), noisy environments are a stressor to speech production. Recently, the intelligibility of speech from PD talkers speaking in noisy (additive multi-talker babble) and reverberant environments was shown to be ...
Réfrégier Philippe - - 2014
The degree of coherence of scalar light remains constant when the fields are modified by the same random linear transformation, which can be represented by the multiplication by a random complex number. This shows that the coherence properties of scalar light at order two are not modified with the increase ...
Dasgupta Basudeb B International Centre for Theoretical Physics, Strada Costiera 11, 34014 Trieste, - - 2014
We show that sterile neutrinos with masses ≳1  eV, as motivated by several short baseline oscillation anomalies, can be consistent with cosmological constraints if they are charged under a hidden sector force mediated by a light boson. In this case, sterile neutrinos experience a large thermal potential that suppresses mixing between ...
Basak Shibaji S Department of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata - 700 032, India. - - 2014
A series of amphiphilic tyrosine based self-healable, multi-stimuli responsive metallo-hydrogels have been discovered. Formation of these hydrogels is highly selective to Ni(2+) ions. The self-healing property and the stiffness of these metallo-hydrogels can be tuned by varying the chain length of the corresponding gelator amphiphile.
Huang Chuan C Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA 02114; Department of Radiology, Harvard Medical School, Boston, MA 02115. Electronic address: - - 2014
Brain PET scanning plays an important role in the diagnosis, prognostication and monitoring of many brain diseases. Motion artifacts from head motion are one of the major hurdles in brain PET. In this work, we propose to use wireless MR active markers to track head motion in real time during ...
Ebana Hideaki H Division of Hematology/Oncology, Shirakawa Kosei General Hospital, 2-1 Toyochi Kamiyajirou, Shirakawa, Fukushima 961-0005, - - 2014
In the past decade, the serum free light chain (FLC) immunoassays have become widely available enabling greater sensitivity in the diagnosis and management of monoclonal light chain diseases. Here, we describe a rare case of serum free light chain only myeloma with cytoplasmic IgM. A 75-year-old woman presented with a ...
Lindholm Markus M Norwegian Institute for Water Research/NIVA, Gaustadalleen 23, 0349 Oslo, - - 2014
The essay discusses whether biotic and abiotic environments differ in their ability to speed up or slow down morphological change and the generation of new lineages. Examples from the class Branchiopoda show that morphological conservatism is associated with enemy free space in species-poor habitats dominated by abiotic factors, while Red ...
Farokhmanesh Khatere - - 2014
Based on clinical observations, foot hyperpronation is very common. Excessive pronation (hyperpronation) can cause malalignment of the lower extremities. This most often leads to functional and structural deficits. The aim of this study was to assess the effect of foot hyperpronation on lumbar lordosis and thoracic kyphosis. Thirty five healthy ...
Bai Yuanyuan Y Department of Design, Kyushu University, 4-9-1, Shiobaru, Minami-ku, Fukuoka-shi 815-8540, Japan; e-mail: - - 2014
The pursuit-pursuing illusion is a visual illusion where a circular object placed in the centre of a radial pattern consisting of thin sectors is seen to move in the pursuit eye movement direction. The present study investigates the role of the surrounding texture, replacing the sectors with random dots or ...
Plack Christopher J CJ University of Manchester, UK - - 2014
Dramatic results from recent animal experiments show that noise exposure can cause a selective loss of high-threshold auditory nerve fibers without affecting absolute sensitivity permanently. This cochlear neuropathy has been described as hidden hearing loss, as it is not thought to be detectable using standard measures of audiometric threshold. It ...
Leo Fabrizio F Max Planck Institute for Biological Cybernetics, Tübingen, Germany; Institute of Biological Psychology, Otto-von-Guericke University, Magdeburg, Germany; Department of Robotics, Brain and Cognitive Sciences, Istituto Italiano di Tecnologia, Genova, - - 2014
This psychophysics study investigated whether prior auditory conditioning influences how a sound interacts with visual perception. In the conditioning phase, subjects were presented with three pure tones ( =  conditioned stimuli, CS) that were paired with positive, negative or neutral unconditioned stimuli. As unconditioned reinforcers we employed pictures (highly pleasant, unpleasant ...
Schoonderwaldt Erwin E Institute of Music Physiology and Musicians' Medicine, Hanover University of Music, Drama and Media, Hanover, - - 2014
We present a study of coordination behavior in complex violin-bowing patterns involving simultaneous bow changes (reversal of bowing direction) and string crossings (changing from one string to another). Twenty-two violinists (8 advanced amateurs, 8 students with violin as major subject, and 6 elite professionals) participated in the experiment. We investigated ...
Wu Jianghong J Inner Mongolia Prataculture Research Center, Chinese Academy of Science, Hohhot, China; Animal Husbandry Institute, Inner Mongolia Academy of Agricultural & Animal Husbandry Sciences, Hohhot, China; Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, - - 2014
Stimulated by retinoic acid 6 (STRA6) is the receptor for retinol binding protein and is relevant for the transport of retinol to specific sites such as the eye. The adaptive evolution mechanism that vertebrates have occupied nearly every habitat available on earth and adopted various lifestyles associated with different light ...
Riecke Lars L Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The - - 2014
Auditory selective attention plays an essential role for identifying sounds of interest in a scene, but the neural underpinnings are still incompletely understood. Recent findings demonstrate that neural activity that is time-locked to a particular amplitude-modulation (AM) is enhanced in the auditory cortex when the modulated stream of sounds is ...
Kaleta Erin - - 2013
Abstract Background: The objective of this study was to evaluate the performance of the heavy/light chain and free light chain immunoassays in patients with heavy chain disease, and to assess the ability of the heavy/light chain assay to measure and confirm the abnormal, truncated heavy chain. Methods: Frozen serum samples ...
Sievert Lynnette Leidy - - 2013
Up to 75% of women in the US report having experienced hot flashes during the menopausal transition. The purpose of this review is to describe the physiology of hot flashes, and the ways in which hot flashes have been examined by subjective report and by objective measurement. Hot flashes occur ...
Zemlin Annalise E - - 2013
Monoclonal serum free light chain measurements are used to follow up and manage patients with monoclonal gammopathies, and abnormal serum free light chain ratios are associated with risk of progression in certain diseases. We aimed to validate the reference intervals in our population. Reference intervals for κ and λ free ...
Hubbard Timothy L - - 2013
If an observer sees a flashed (briefly presented) object that is aligned with a moving target, the perceived position of the flashed object usually lags the perceived position of the moving target. This has been referred to as the flash-lag effect, and the flash-lag effect has been suggested to reflect ...
Uzoigwe Ossie Ferdinand - - 2013
Handedness remains an enigmatic phenomenon. There is no definitive explanation as to why man should have single rather than dual handedness. Intuitively it would seem advantageous in almost every context to have the benefit of equally dextrous hands. Either in context of warfare or hunting, using two hands equally as ...
van den Bos R A J M - - 2013
To investigate the cold and hot re-ignition properties of High Intensity Discharge (HID) lamps in more detail an automated setup was designed in such a way that HID lamps of various sizes and under different background pressures can be tested. The HID lamps are ignited with a ramped sinusoidal voltage ...
Picken Maria M - - 2013
Among the various systemic amyloidoses, deposits derived from the immunoglobulin light chain (AL) account for 85% of cases. In this issue, Nasr et al. report 16 cases of renal heavy and light+heavy chain amyloidosis and compare them with renal light chain amyloidosis. While additional studies are needed to shed light ...
Haywood Jessica J Department of Pharmaceutical Chemistry, 2095 Constant Avenue, University of Kansas, 2095 Constant Avenue, Lawrence, Kansas 66047, - - 2013
The exposure of IgG1 in aqueous solution to light with λ = 254 nm or λ > 295 nm yields products consistent with Trp radical cation formation followed by (α)C-(β)C cleavage of the Trp side chain. The resulting glycyl radicals either are reduced to Gly or add oxygen prior to ...
Brebner Judith A - - 2013
Free light chains are proteins produced by B lymphocytes during the process of antibody synthesis. Their production, as a reflection of B cell activation, can give insight into the activity of the adaptive immune system. In recent years, an automated immunoassay that provides quantitative measurement of free light chains in ...
Komatsuda Atsushi - - 2013
A 45-year-old man presented with moderate proteinuria and hematuria. A renal biopsy showed mesangial/endocapillary proliferative glomerulonephritis, linear deposition of monoclonal immunoglobulin γ1 C(H) 2 heavy chain along glomerular and tubular basement membranes (GBMs and TBMs), granular deposition of κ light chain within the mesangial area, and continuous linear deposits of ...
Lu Connie C Protein Analytical Chemistry, Genentech Inc., South San Francisco, CA, USA. - - 2013
Size exclusion chromatography (SEC) is the most commonly used method to separate and quantify monoclonal antibody (mAb) size variants. MAb-A is an IgG1 subtype humanized monoclonal antibody recombinantly produced in Chinese hamster ovary (CHO) cells. SEC analysis of MAb-A resolved a peak, named Peak 1, which elutes between monomer and ...
Clark Robin J H - - 2012
The key contributions of the four great Nobel Laureates - Lord Rayleigh, Sir William Ramsay, Lord Rutherford and Sir Chandrasekhara Raman - to the understanding of light scattering, to the identification and classification of the rare gases, and to the discovery in 1928 of the Raman effect are outlined. The ...
van Velzen Jeroen F - - 2012
BACKGROUND: Multicolor flow cytometry (MFC) is increasingly important for the diagnosis and minimal residual disease (MRD) assessment of patients with plasma cells (PC) dyscrasias, like multiple myeloma. Recently published information shows that immunophenotype of myeloma PC can change over time and normal PC are heterogeneous in the expression of CD19 ...
Sanders Paul W - - 2012
The tubular nephron is responsible for reabsorption and catabolism of filtered low molecular weight proteins that include Ig free light chains. In the setting of a plasma cell dyscrasia, significant amounts of free light chains, now monoclonal proteins, present to the tubular nephron for disposal. The result may be clinical ...
Nitschke Udo - - 2012
The potential of algae to acclimate to environmental stress is commonly assessed using chlorophyll a fluorescence, with changes in parameters of photosynthesis versus irradiance (P/E) curves measured either as rapid light curves (RLC) or steady-state light curves (LC). Here, effects of emersion on primary photosynthesis of four brown macroalgae (Ascophyllum ...
Schlerf John E - - 2012
The cerebellum is critically important for error-driven adaptive motor learning, as evidenced by the fact that cerebellar patients do not adapt well to sudden predictable perturbations. However, recent work has shown that cerebellar patients adapt much better if the perturbation is gradually introduced. Here we explore physiological mechanisms that underlie ...
Fairhurst Merle T - - 2012
Cooperation is intrinsic to the human ability to work together toward common goals, and depends on sensing and reacting to dynamically changing relationships between coacting partners. Using functional magnetic resonance imaging (fMRI) and a paradigm in which an adaptive pacing signal simulates a virtual partner, we examined the neural substrates ...
Macdermid Paul William - - 2012
Abstract The purpose was to assess the mechanical work and physiological responses to cross country mountain bike racing. Participants (n = 7) cycled on a cross country track at race speed whilst [Formula: see text]O(2), power, cadence, speed, and geographical position were recorded. Mean power during the designated start section (68.5 ± 5.5 s) was ...
Robinson Alan E - - 2012
Prolonged viewing of a flickering region reduces sensitivity to a subsequently flickered test patch of identical extent, but the spatial properties of this adaptation are unknown. What happens to the sensitivity to a smaller flickered test patch completely contained in, but inset from, the adapted region? We show that sensitivity ...
Chandrasekhar Vadapalli - - 2012
A new water-soluble, multisite-coordinating ligand LH(7) was prepared by the condensation of tris(hydroxymethyl)aminomethane with 2,6-diformyl-p-cresol. LH(7) is a selective chemosensor for Cu(2+), under physiological conditions, with visual detection limits of 20 ppm (ambient light conditions) and 4 ppm (UV light conditions). LH(7) can also be used in biological cell lines ...
Culumber Z W - - 2012
Local adaptation is often invoked to explain hybrid zone structure, but empirical evidence of this is generally rare. Hybrid zones between two poeciliid fishes, Xiphophorus birchmanni and X. malinche, occur in multiple tributaries with independent replication of upstream-to-downstream gradients in morphology and allele frequencies. Ecological niche modelling revealed that temperature is ...
Hummel Dennis - - 2012
Visual perception can be strongly biased due to exposure to specific stimuli in the environment, often causing neural adaptation and visual aftereffects. In this study, we investigated whether adaptation to certain body shapes biases the perception of the own body shape. Furthermore, we aimed to evoke neural adaptation to certain ...
Thomas Monika M Institute of Physiology and Anatomy, German Sport University Cologne, Am Sportpark Müngersdorf 6, 50933 Cologne, Germany. - - 2012
The human sensorimotor system can concurrently adapt to two different distortions without interference when the distortions are cued by different contexts. We investigated whether this holds with four distortions as well. Subjects were exposed to an interlaced sequence of +30°, -30°, +60°, and -60° visuomotor rotations as the adaptation phase, ...
Maier J K JK UCL Ear Institute, London, United - - 2012
Many neurons adapt their spike output to accommodate the prevailing sensory environment. Although such adaptation is thought to improve coding of relevant stimulus features, the relationship between adaptation at the neural and behavioral levels remains to be established. Here we describe improved discrimination performance for an auditory spatial cue (interaural ...
De La Garza Bryan H - - 2012
To employ functional manganese-enhanced MRI (MEMRI) to image layer-specific changes in calcium-dependent activities in the rat retina during light versus dark adaptation. Functional MEMRI at 20 × 20 × 700 μm was used to study light and dark adaptation in the same animals (N = 10) in which one eye ...
Brown Andrew D - - 2012
Human listeners' sensitivity to interaural time differences (ITD) was assessed for 1000 Hz tone bursts (500 ms duration) preceded by trains of 500-ms "adapter" tone bursts (7 s total adapter duration, frequencies of 200, 665, 1000, or 1400 Hz) carrying random ITD, or by an equal-duration period of silence. Presentation ...
Patel Rita R - - 2012
OBJECTIVE: To clinically evaluate changes in vocal fold vibration and voice production caused by voice therapy in hoarseness resulting from contact granuloma. DESIGN: Single-subject before-after prospective study using multiple measures of vocal function. A 6-week program of vocal function exercises (VFEs) was conducted using multiple assessments of vocal function to ...
Bailey Susan F - - 2012
Abstract Abundant ecological opportunity is thought to drive adaptation and diversification. The presence of multiple opportunities leads to divergent selection, which can slow adaptation when niche-specific beneficial mutations have antagonistically pleiotropic effects. Alternately, competition for multiple opportunities can generate divergent selection, which leads to high rates of adaptive differentiation. Which ...
Hoshii Yoshinobu - - 2012
For the purpose of investigating the carboxy terminus distribution of immunoglobulin κ light chain in Aκ amyloid deposits in tissue sections, we examined the immunostaining pattern of Aκ amyloidosis with conventional rabbit clonal antibody against peptide derived from the C-terminal sequence of human κ light chain. This antihuman kappa light ...
Kristjánsson Arni - - 2012
The range of variation in environmental stimuli is much larger than the visual system can represent. It is therefore sensible for the system to adjust its responses to the momentary input statistics of the environment, such as when our pupils contract to limit the light entering the eye. Previous evidence ...
Koshelskaja E V - - 2012
Physiological and biomechanical characteristics of the kick and goal technique in football were studied in athletes of different qualification. The formation of technological skills of football players kicking the ball from the standard position requires coordinated movements and high differentiation of muscular activity.
Buckeridge John S - - 2012
Cirripede-like organisms have their origins in the Palaeozoic, but until the Cainozoic, were represented primarily by pedunculated forms, such as the Scalpelliformes. Acorn barnacles (Balanomorpha) are first recorded after the Cretaceous-Tertiary extinction event. During the late Palaeogene, rapid radiation of cirripedes resulted in sufficient diversification for them to occupy most ...
Bakalar M - - 2012
When conducting optical imaging experiments, in vivo, the signal to noise ratio and effective spatial and temporal resolution is fundamentally limited by physiological motion of the tissue. A three-dimensional (3D) motion tracking scheme, using a multiphoton excitation microscope with a resonant galvanometer, (512 × 512 pixels at 33 frames s(-1)) ...
Saraiva J L - - 2012
The inter-populational variation in the reproductive behaviour of the peacock blenny Salaria pavo (Risso 1810), particularly the influence of the ecologic environment, was reviewed in the present work. Two populations of this species inhabiting contrasting environments were studied: the Ria Formosa population, a coastal lagoon with sandy/muddy substrate located in ...
García-Sánchez Marta - - 2012
The macroalga Caulerpa prolifera colonized the Mar Menor coastal lagoon after the enlargement of the main inlet in 1972, coexisting now with the previous Cymodocea nodosa meadows. The physiological response and the photoacclimation capacity of both species were studied. For this purpose in vivo chlorophyll a fluorescence, photoprotective mechanisms and ...
Frank Marion E - - 2012
Little is known about coding of taste mixtures in complex dynamic stimulus environments. A protocol developed for odor stimuli was used to test whether rapid selective adaptation extracted sugar and salt component tastes from mixtures as it did component odors. Seventeen human subjects identified taste components of "salt + sugar" ...
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