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Arts Remo A G J RA Department of ENT/Head and Neck Surgery, Maastricht University Medical Centre, Maastricht, The - - 2014
Research on tinnitus suppression by intracochlear electrical stimulation has gained interest over the past few decades and it has become easier to apply since the introduction of cochlear implants (CI). This study attempted to gain more insight into optimal stimulation characteristics for tinnitus suppression. Eleven subjects with unilateral CI and ...
Rahman Mostafeezur M Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Moos Tower 18-186, 515 Delaware St. SE, Minneapolis, MN 55455, USA. Electronic address: - - 2014
Cornea-evoked eyeblinks maintain tear film integrity on the ocular surface in response to dryness and protect the eye from real or potential damage. Eyelid movement following electrical stimulation has been well studied in humans and animals; however, the central neural pathways that mediate protective eyeblinks following natural nociceptive signals are ...
Rollins Mark D MD From the Departments of Anesthesia and Perioperative Care and Surgery (M.D.R.), Department of Anesthesia and Perioperative Care (J.R.F.), Department of Anesthesia and Perioperative Care (M.L.), University of California, San Francisco, California; Department of Pediatrics, University of California, Fresno, California (J.M.L.); and Department of Anesthesia, University of California, San Diego, California - - 2014
The pupillary light reflex is a critical component of the neurologic examination, yet whether it is present, depressed, or absent is unknown in patients with significant opioid toxicity. Although opioids produce miosis by activating the pupillary sphincter muscle, these agents may induce significant hypercarbia and hypoxia, causing pupillary constriction to ...
Morales-Quezada Leon L aSpaulding Neuromodulation Center, Spaulding Rehabilitation Hospital, Harvard Medical School, Boston, Massachusetts, USA bSchool of Health Sciences, De Montfort University, Leicester, - - 2014
Defining optimal parameters for stimulation is a critical step in the development of noninvasive neuromodulation techniques. Transcranial pulsed current stimulation (tPCS) is emerging as another option in the field of neuromodulation; however, little is known about its mechanistic effects on electrical brain activity and how it can modulate its oscillatory ...
Chiang Chia-Chu CC Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, - - 2014
Electrical high frequency stimulation (HFS) has been shown to suppress seizures. However, the mechanisms of seizure suppression remain unclear and techniques for blocking specific neuronal populations are required. The goal is to study the optical HFS protocol on seizures as well as the underlying mechanisms relevant to the HFS-mediated seizure ...
Yan Hugen H IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598, United - - 2014
In the phenomenon of plasmon-induced transparency, which is a classical analogue of electromagnetically induced transparency (EIT) in atomic gases, the coherent interference between two plasmon modes results in an optical transparency window in a broad absorption spectrum. With the requirement of contrasting lifetimes, typically one of the plasmon modes involved ...
Quandt Gabriele - - 2014
Inhibition of mGAT1, the most abundant GABA transporter in the brain, enhances GABA signaling and alleviates symptoms of CNS disorders such as epilepsy assumed to be associated with low GABA levels. We have now developed a potent and subtype selective photoswitchable inhibitor of this transporter which for the first time ...
Lu Ying-Jie - - 2014
ZnO p-n homojunction light-emitting devices (LEDs) have been fabricated, and by introducing a p-type GaN as the hole-injection layer, the output power of the LEDs can reach 18.5 μW when the drive current is 60 mA, which is almost three orders of magnitude larger than the pristine LEDs without the ...
Maximino Caio C Departamento de Morfologia e Ciências Fisiológicas, Universidade do Estado do Pará, Marabá, PA, Brazil; Zebrafish Neuroscience Research Consortium. Electronic address: - - 2014
Alarm reactions to a substance secreted by the damaged skin of conspecifics and closely-related species are increasingly being recognized as fear-like responses in fish. The neurochemical underpinnings of these effects are so far unknown; however, given the role of the serotonergic system on defensive behavior, it is possible that the ...
Feinkohl Arne A Cluster of Excellence Hearing4all, Animal Physiology and Behaviour Group, Department for Neuroscience, School of Medicine and Health Sciences, University of Oldenburg, D-26111 Oldenburg, Germany - - 2014
"Representational Momentum" (RM) is a mislocalization of the endpoint of a moving target in the direction of motion. In vision, RM has been shown to increase with target velocity. In audition, however, the effect of target velocity is unclear. Using a perceptual paradigm with moving broadband noise targets in Virtual ...
Cheng Min-Chi - - 2014
By up-shifting the relaxation oscillation peak and suppressing its relative intensity noise in a weak-resonant-cavity Fabry-Perot laser diode (WRC-FPLD) under intense injection-locking, the directly modulated transmission of optical 16 quadrature amplitude modulation (QAM) orthogonal frequency division multiplexing (OFDM) data-stream is demonstrated. The total bit rate of up to 20 Gbit/s ...
Zhang Tian-Zi TZ Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China; Affiliated Hospital of Inner MongonliaUniversity For the Nationalities, Inner Mongonlia, - - 2014
Autophagy, a conserved cellular self-degradation process, not only serves to protect cells at critical times during development and nutrient stress, but also contributes to cell death. Photoreceptor cells are unique neurons which when directly exposed to the light, transduces light stimuli into visual signal. However, intense light exposure can be ...
Tse Dennis Y DY Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, Texas, USA. Electronic address: - - 2014
A remarkable feature of neuronal glutamate transporters (EAATs) is their dual functions of classical carriers and ligand-gated chloride (CI(-)) channels. CI(-) conductance is rapidly activated by glutamate in subtype EAAT5, which mediates light responses in depolarizing bipolar cells (DBC) in retinae of lower vertebrates. In this study, we examine whether ...
Tejeda Hugo A HA Synaptic Plasticity Section, Cellular Neurobiology Research Branch, National Institute on Drug Abuse, Baltimore, MD 21224, - - 2014
Excessive sun tanning can result in addictive behavior. In this issue of Cell, Fell et al. utilize a combination of behavioral pharmacology and transgenic mice to demonstrate that chronic UV light exposure recruits p53 signaling in keratinocytes, subsequently increasing β-endorphin signaling at opioid receptors, and produces an endogenous opioid-dependent state.
Ozturk Murat M Department of Otolaryngology, Faculty of Medicine, Kocaeli University, KBB Anabilim Dali, Umuttepe, 41380 Kocaeli, - - 2014
Alprazolam, a widely used drug, has widespread, nonspecific depressant effects on the central nervous system, similar to other benzodiazepines. This inhibitor effect may cause changes in reflex thresholds by affecting the acoustic stapedial reflex (ASR) arc. This study was performed on 31 healthy volunteers. Initially, the basal ASR thresholds were ...
Guffey J Stephen JS J. Stephen Guffey, PT, EdD, is an Associate Professor of Physical Therapy; William Payne, MS, ASCP(MT), is an Assistant Professor of Clinical Laboratory Science; Leslie James, BS, is a Doctor of Physical Therapy Student; Zhuoyuan Qian, BS, is a Doctor of Physical Therapy Student; and Carly Dodson is a Clinical Laboratory Science Student; all at Arkansas State University, Jonesboro, Arkansas. Dr Guffey has disclosed that he is a consultant for Dynatronics Corporation. The coauthors have disclosed that they have no financial relationships related to this - - 2014
To determine the potential for visible light (405 or 624 nm) to produce an inhibitory effect on Candida albicans. In addition, the study sought to evaluate a series of doses in terms of their respective inhibiting capabilities. The authors have studied the effect of blue light on Staphylococcus aureus and ...
Jung Wonsug W *Department of Anatomy, School of Medicine, Gachon University, Inchon, Korea; †Division in Anatomy and Developmental Biology, Department of Oral Biology, BK21 PLUS Project, Human Identification Center, Yonsei University College of Dentistry, Seoul, Korea; ‡Department of Occupational Therapy, College of Health and Welfare, Woosong University, Daejeon, Korea; §Department of Anatomy, Department of Oral Anatomy, Dankook University College of Dentistry, Cheonan, - - 2014
The middle temporal vein (MTV) traverses the temporal fossa between the superficial and deep layers of the deep temporal fascia. During filler injection into a deficient temporal fossa, filling agents may be inadvertently injected into the MTV, which results in vascular complications. To investigate the course of the MTV to ...
Nakajima Takahito - - 2014
Photoimmunotherapy (PIT) is a highly cell-selective cancer therapy, which employs monoclonal antibodies conjugated to a potent photosensitizer (mAb-IR700). Once the conjugate has bound to the target cell, exposure to near infrared (NIR) light induces necrosis only in targeted cells with minimal damage to adjacent normal cells in vivo. Herein, we ...
Christie John J a Psychology and Neuroscience, Dalhousie University , Halifax , NS , - - 2014
Christie and Klein [2005. Does attention cause illusory line motion? Perception & Psychophysics, 67(6), 1032-1043] published line motion ratings consistent with illusory line motion (ILM) after peripheral endogenous cues but not central arrow cues. When attention was directed endogenously on the basis of the shape of one of two peripherally ...
Delgado Ricardo R Department of Biology, Faculty of Sciences, University of Chile, 7800024 Santiago, Chile, Biotechnology Center D. Alkalay L., Technical University Federico Santa María, 2340000 Valparaíso, Chile, and Max Planck Institute of Molecular Plant Physiology, 14776 Potsdam, - - 2014
Drosophila light-dependent channels, TRP and TRPL, reside in the light-sensitive microvilli of the photoreceptor's rhabdomere. Phospholipase C mediates TRP/TRPL opening, but the gating process remains unknown. Controversial evidence has suggested diacylglycerol (DAG), polyunsaturated fatty acids (PUFAs, a DAG metabolite), phosphatidylinositol bisphosphate (PIP2), and H(+) as possible channel activators. We tested ...
Xu Yameng - - 2014
An asymmetric directional coupler scheme for the efficient injection of light into slow light slot photonic crystal waveguide modes is proposed and investigated using finite-difference time-domain simulation. Coupling wavelengths can be flexibly controlled by the geometrical parameters of a side-coupled subwavelength corrugated strip waveguide. This approach leads to a ~1dB ...
Hisatomi Osamu O Osaka University, - - 2014
Aureochrome-1 (AUREO1) is a blue light (BL) receptor that mediates the branching response in stramenopile alga, Vaucheria frigida. AUREO1 contains a basic leucine zipper (bZIP) domain in the central region and a light-oxygen-voltage-sensing (LOV) domain at the C-terminus, and has been suggested to function as a light-regulated transcription factor. We ...
Nishimura Takayuki - - 2014
Previous reports have shown that higher altitudes can alter human perception. We add further evidence to this claim, describing a new finding in which higher altitudes inhibit the perception of illusory self-motion, i.e., vection. We compared vection strength under both normal and high altitude (hypobaric hypoxia) conditions. In the high ...
Tsakmakidis Kosmas L KL Blackett Laboratory, Department of Physics, Imperial College London, London SW7 2AZ, United - - 2014
We introduce a scheme where a time-dependent source excites "complex-frequency" modes in uniform plasmonic heterostructures, enabling complete and dispersionless stopping of light pulses, resilient to realistic levels of dissipative, radiative, and surface-roughness losses. Using transparent conducting oxides at telecommunication wavelengths we show how, without increasing optical losses, multiple light pulses ...
Jayaswal G - - 2014
Weak measurements have recently allowed for the observation of the spin-Hall effect of light in reflection or transmission, which is a spin-dependent light beam shift orthogonal to the plane of incidence. We report here the observation of the Imbert-Fedorov (IF) shift via a weak value amplification scheme. The IF effect ...
Chen Horng-Shyang - - 2014
A reverse-biased voltage is applied to either device in the vertical configuration of two light-emitting diodes (LEDs) grown on patterned and flat Si (110) substrates with weak and strong quantum-confined Stark effects (QCSEs), respectively, in the InGaN/GaN quantum wells for independently controlling the applied voltage across and the injection current ...
Guaraldi Pietro P IRCCS Istituto delle Scienze Neurologiche di Bologna , Bologna , Italy - - 2014
Circadian rhythms were recently proposed as a measure of physiological state and prognosis in disorders of consciousness (DOC). So far, melatonin regulation was never assessed in vegetative state (VS). Aim of our research was to investigate the nocturnal melatonin levels and light-induced melatonin suppression in a cohort of VS patients. ...
Wietek Jonas J Institute for Biology, Experimental Biophysics, Humboldt Universität zu Berlin, D-10115 Berlin, - - 2014
The field of optogenetics utilizes channelrhodopsins (ChRs) for light-induced neuronal activation. Optimized tools for cellular inhibition at moderate light levels are however lacking. We found that replacement of E90 in the central gate of ChR with positively charged residues produces chloride-conducting ChRs (ChloCs) with only negligible cation conductance. Molecular dynamics ...
Otsmane Belkacem B The Mediterranean Institute of Neurobiology, Inmed, Marseille, - - 2014
A receptor-ligand interaction can evoke a broad range of biological activities in different cell types depending on receptor identity and cell-type-specific post-receptor signaling intermediates. Here, we show that the TNF family member LIGHT, known to act as a death-triggering factor in motoneurons through LT-βR, can also promote axon outgrowth and ...
Sharkhuu Altanbadralt A Department of Biological and Environmental Science and Engineering, King Abdullah University of Science and Technology, Thuwal, 23955-6900, Jeddah, Kingdom of Saudi Arabia; Department of Horticulture and Landscape Architecture, Purdue University, 47907, West Lafayette, Indiana, - - 2014
Glyphosate is a widely applied broad-spectrum systemic herbicide that competitively inhibits the penultimate enzyme, 5-Enolpyruvylshikimate 3-Phosphate Synthase (EPSPS), of the shikimate pathway thereby causing deleterious effects. A glyphosate resistant Arabidopsis mutant (gre1) was isolated and genetic analyses indicated a dysfunctional red (R) and far-red (FR) light receptor, phytochrome B (phyB), ...
Narimatsu Toshio T Laboratory of Retinal Cell Biology; Department of Ophthalmology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, - - 2014
Exposure to light contributes to the development and progression of retinal degenerative diseases. However, the mechanisms underlying light-induced tissue damage are not fully understood. Here, we examined the role of angiotensin II type 1 receptor (AT1R) signaling, which is part of the renin-angiotensin system (RAS), in light-induced retinal damage. Light-exposed ...
Marshak Tal T Unit of Otoneurology, Lin Medical Center, Haifa, - - 2014
To examine the role of intratympanic Dexamethasone (ITD) in the prevention of Cisplatin-induced hearing loss. Prospective randomized controlled clinical trial. Tertiary referral center. Twenty-six patients suffering from a neoplastic disease for which the treatment protocol included Cisplatin were recruited. Prior to each Cisplatin treatment session ITD was injected to the ...
Beiert Thomas T Institute of Physiology I, Life & Brain Center, University of Bonn, - - 2014
Investigation of Gq-signaling with pharmacological agonists of Gq-coupled receptors lacks spatio-temporal precision. The aim of this study was to establish melanopsin, a light-sensitive Gq-coupled receptor, as a new tool for the investigation of spatial and temporal effects of Gq-stimulation on pacemaking in cardiomyocytes at an early developmental stage.Methods and ResultsA ...
Abramian Miganoosh M Graduate School of Biomedical Engineering, University of New South Wales, Sydney, - - 2014
Objective. In this study we investigated the feasibility of quasi-monopolar (QMP) electrical stimulation for retinal implant devices, using a computational model of the retinal ganglion cell layer. Approach. When used with hexagonally arrayed multiple electrodes, QMP stimulation is a hybrid of hexapolar and conventional monopolar stimulus modes. In hexapolar mode, ...
Lindsay Jonathan H JH Department of Biochemistry and Cellular and Molecular Biology, University of Tennessee, Knoxville, - - 2014
Ethanol (EtOH) triggers cellular adaptations that induce tolerance in many brain areas, including the suprachiasmatic nucleus (SCN), the site of the master circadian clock. EtOH inhibits light-induced phase shifts in the SCN in vivo and glutamate-induced phase shifts in vitro. The in vitro phase shifts develop acute tolerance to EtOH, ...
Zheng Yan Y Department of Military Hygiene, Faculty of Naval Medicine, Second Military Medical University, 800 Xiang Yin Road, Shanghai, China; Department of Nutrition, Tong Ren Hospital Affiliated to Shanghai JiaoTong University School of Medicine, 1111 Xian Xia Road, Shanghai, China. Electronic address: - - 2014
Low-dose dexamethasone has been widely used for the prevention of nausea and vomiting after chemotherapy and surgical procedures and to treat motion sickness due to its minimal adverse effects, but the mechanisms underlying its anti-motion sickness effects are poorly understood. Previous studies have demonstrated that the endocannabinoid system is suppressed ...
Gu Xiao-Jing XJ State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China ; University of Chinese Academy of Sciences, Beijing, - - 2014
The idea of retinal and ex-retinal sources of saccadic suppression has long been established in previous studies. However, how they are implemented in local circuit remains unknown. Researchers have suggested that saccadic suppression was probably achieved by contrast gain control, but this possibility has never been directly tested. In this ...
Takamizawa Akifumi - - 2014
In this study, incoherent light with a spectral linewidth of 7 nm and 140 mW of power was generated from a laser diode (LD) into which incoherent light emitted from a superluminescent diode was injected with 2.7 mW of power. The spectral linewidth of the light from the LD was broadened to 12 nm ...
Cheron G G Laboratory of Electrophysiology, Université de Mons, 7000 Mons, Belgium; Laboratory of Neurophysiology and Movement Biomechanics, CP601, ULB Neurosciences Institut, Université Libre de Bruxelles, 1070 Brussels, Belgium. Electronic address: - - 2014
Purkinje cell (PC) firing represents the sole output from the cerebellar cortex onto the deep cerebellar and vestibular nuclei. Here, we explored the different modes of PC firing in alert mice by extracellular recording. We confirm the existence of a tonic and/or bursting and quiescent modes corresponding to UP and ...
Chung Seok Jong SJ Department of Neurology (SJC), Yonsei University College of Medicine, Seoul, Korea; Department of Neurology (S-HP, J-SK, SWO, HJK, JHP, YEH), Seoul National University Bundang Hospital, Seongnam-si, Korea; and Department of Neurology (S-HP, J-SK), Seoul National University College of Medicine, Seoul, - - 2014
: A 43-year-old man with a high-grade glioma involving the cerebellar nodulus showed a near-complete suppression of periodic alternating nystagmus (PAN) in the lateral decubitus position to either side. This positional modulation of PAN is consistent with suppression of the velocity storage mechanism by head position changes (tilt dumping) and ...
Jones Rebecca S RS Dominick P. Purpura Department of Neuroscience and Department of Ophthalmology and Visual Sciences, Albert Einstein College of Medicine, The Rose F. Kennedy Center, Bronx, New York - - 2014
Retinal ganglion cells (RGCs) receive glutamatergic input from bipolar cells through NMDA- and AMPA-type glutamate receptors. Both GluA2-containing, Ca(2+)-impermeable AMPA receptors (CI-AMPARs) and GluA2-lacking, Ca(2+)-permeable AMPA receptors (CP-AMPARs) contribute to light-evoked responses in ON RGCs; however, specific roles for each subtype are not well understood. Here, we present evidence that ...
Janson Jolanda J Carl von Ossietzky University, Oldenburg, - - 2014
The attentional blink (AB) is a deficit in conscious perception of the second of two targets if it follows the first within 200-500 msec. The AB phenomenon has been linked to pretarget oscillatory alpha activity. However, this is based on paradigms that use a rapid serial visual presentation (RSVP) stimulus ...
Trenado Carlos C Department of Neurology and Neurophysiology, Albert-Ludwigs-University Freiburg, - - 2014
Modern attempts to improve human performance focus on stochastic resonance (SR). SR is a phenomenon in non-linear systems characterized by a response increase of the system induced by a particular level of input noise. Recently, we reported that an optimum level of 0-15 Hz Gaussian noise applied to the human ...
Chung Charles Y L CY The School of Optometry and Vision Science, The University of New South Wales, Kensington NSW, - - 2014
In the present study we addressed whether the processing of global form and motion was dependent on visual awareness. Continuous flash suppression (CFS) was used to suppress from awareness global dot motion (GDM) and Glass pattern stimuli. We quantified the minimum time taken for both pattern types to break suppression ...
Hothersall Becky B School of Veterinary Science, University of Bristol, Bristol, United - - 2014
Lameness is common in commercially reared broiler chickens but relationships between lameness and pain (and thus bird welfare) have proved complex, partly because lameness is often partially confounded with factors such as bodyweight, sex and pathology. Thermal nociceptive threshold (TNT) testing explores the neural processing of noxious stimuli, and so ...
Usubuchi Hajime H Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, Sendai, Miyagi, - - 2014
The auditory steady state response (ASSR) is an oscillatory brain response, which is phase locked to the rhythm of an auditory stimulus. ASSRs have been recorded in response to a wide frequency range of modulation and/or repetition, but the physiological features of the ASSRs are somewhat different depending on the ...
McCracken Clinton B CB Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, - - 2014
High-frequency electrical stimulation of specific brain structures, known as deep brain stimulation (DBS), is an effective treatment for movement disorders, but mechanisms of action remain unclear. We examined the time-dependent effects of DBS applied to the entopeduncular nucleus (EP), the rat homolog of the internal globus pallidus, a target used ...
Iliopoulos Fivos F MPI for Human Cognitive and Brain - - 2013
While noise is usually considered to be harmful for signal detection and information transmission, Stochastic Resonance (SR) describes the counterintuitive phenomenon of noise enhancing the detection and transmission of weak input signals. In mammalian sensory systems SR related phenomena may arise both in the peripheral and the central nervous system. ...
Gannon Robert L RL Department of Biology, Valdosta State University, Valdosta, Georgia, USA. Electronic address: - - 2013
Many physiological systems in mammals are linked to the body's master circadian rhythm in the sleep/wake cycle and dysfunctions in this rhythm has been associated with neurological diseases such as major depression, Alzheimer's Disease and schizophrenia. There is some evidence that nicotinic cholinergic input to the master circadian pacemaker, the ...
Newman Ehren L EL Center for Memory and Brain, Department of Psychology, Boston University, Boston, Massachusetts 02215 and Graduate Program, Division of Biological Sciences and Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San Diego, La Jolla, California - - 2013
Large-scale neural activation dynamics in the hippocampal-entorhinal circuit local field potential, observable as theta and gamma rhythms and coupling between these rhythms, is predictive of encoding success. Behavioral studies show that systemic administration of muscarinic acetylcholine receptor antagonists selectively impairs encoding, suggesting that they may also disrupt the coupling between ...
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