Search Results
Results 1 - 50 of 1024
1 2 3 4 5 6 7 8 9 10 >
Qiu Lei L Institute of Microbiology, College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, People's Republic of - - 2014
Phytochromes (Phy) in filamentous fungi are Group VIII histidine kinases which share a unique N-terminal photosensory core but their functions are largely unknown. Here we show that Beauveria bassiana Phy (Bbphy) is functionally vital for growth, conidiation and multi-stress tolerance of the fungal entomopathogen lacking sexual stage. Colony growth of ...
Cyr Adam J AJ BioEngineering Graduate Program, University of Kansas, Lawrence, KS, - - 2014
The interrelationship that exists between multiple degrees of freedom to produce a net constraint across the range of passive motion of the knee is not fully understood. Manual joint laxity assessments were performed on 28 cadaveric specimens and used to develop a unified description of the passive laxity envelope that ...
Gutiérrez Jorge J Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC), Cordel de merinas 52, 37008 Salamanca, - - 2014
Light-grown Arabidopsis thaliana cell suspension culture (ACSC) were subjected to mild photooxidative damage with Rose Bengal (RB) with the aim of gaining a better understanding of singlet oxygen-mediated defence responses in plants. Additionally, ACSC were treated with H2O2 at concentrations that induced comparable levels of protein oxidation damage. Under low ...
Bennett Lea D LD Cell Biology, University of Oklahoma, HSC, Oklahoma City, 73104, United - - 2014
Purpose: Autosomal dominant Stargardt-like macular dystrophy (STGD3) is a juvenile-onset disease that is caused by mutations in ELOVL4 (elongation of very long fatty acids-4). ELOVL4 catalyzes the first step in the conversion of C24 and longer fatty acids (FAs) to very long-chain PUFAs (VLC-FAs, ≥C26). Photoreceptors are particularly rich in ...
Theelen-van den Hoek Femke L FL * Department of Clinical and Experimental Audiology, Academic Medical Center Amsterdam , Meibergdreef, Amsterdam , The - - 2014
Objective: In categorical loudness scaling (CLS), subjects rate the perceived loudness on a categorical scale with alternatives. ISO 16832 describes an internationally standardized CLS procedure for the acoustical domain. This study focuses on the reproducibility of CLS following the recommendations of ISO 16832 using electrical stimuli presented to cochlear implant ...
Sekiya Ryo R Department of Chemistry, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima, 739-8526 - - 2014
Graphene quantum dots (GQDs) have received considerable attention for their potential applications in the development of novel optoelectronic materials. In the generation of optoelectronic devices, the development of GQDs that are regulated in terms of their size and dimensions and are unoxidized at the sp(2) surfaces is desired. GQDs functionalized ...
Lee Tung-Cun - - 2014
Motility in living systems is due to an array of complex molecular nanomotors that are essential for the function and survival of cells. These protein nanomotors operate not only despite of, but also because of stochastic forces. Artificial means of realizing motility rely on local concentration or temperature gradients that ...
Zeng Ling-Li LL Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA - - 2014
Individual differences in brain metrics, especially connectivity measured with functional MRI, can correlate with differences in motion during data collection. The assumption has been that motion causes artifactual differences in brain connectivity that must and can be corrected. Here we propose that differences in brain connectivity can also represent a ...
Lorquet J C JC Department of Chemistry, University of Liège, Sart-Tilman (Bâtiment B6), B-4000 Liège 1, - - 2014
The objective of the present paper is to show the existence of motion coordination among a bundle of trajectories crossing a saddle point region in the forward direction. For zero total angular momentum, no matter how complicated the anharmonic part of the potential energy function, classical dynamics in the vicinity ...
Blasco Eva E Dpt. Química Orgánica, Facultad de Ciencias - Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC, Pedro Cerbuna 12, 50009, Zaragoza, - - 2014
The combination of dendritic and linear polymeric structures in the same macromolecule opens up new possibilities for the design of block copolymers and for applications of functional polymers that have self-assembly properties. There are three main strategies for the synthesis of linear-dendritic block copolymers (LDBCs) and, in particular, the emergence ...
Li J J Laboratory of Anatomy of Domestic Animal, College of Animal Medicine, China Agricultural University, Beijing, 100193, China; Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, - - 2014
Previously, the different monochromatic lights have been demonstrated to affect splenocyte proliferation and melatonin (MEL) secretion in broilers. The present study was designed to evaluate the effects of different monochromatic lights on the development and immune function of broiler cecal tonsils, and to disclose the mechanisms underlying these phenomena. A ...
Orlov Tanya T Neurobiology Department, Life Sciences Institute, The Interdisciplinary Center for Neural Computation and The Edmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel, and FMRIB Centre, Nuffield Department of Clinical Neuroscience, University of Oxford, Oxford OX3 9DU, United - - 2014
Regions in the occipitotemporal cortex (OTC) show clear selectivity to static images of human body parts, and upper limbs in particular, with respect to other object categories. Such selectivity was previously attributed to shape aspects, which presumably vary across categories. Alternatively, it has been proposed that functional selectivity for upper ...
Shcherbina O A - - 2014
Images of semiconductor "dot-in-rods" and their small clusters are studied by measuring the second-order correlation function with a spatially resolving intensified CCD camera. This measurement allows one to distinguish between a single dot and a cluster and, to a certain extent, to estimate the number of dots in a cluster. ...
Kuchenbecker James A - - 2014
The electroretinogram (ERG) provides information about outer retina function in both clinical and research applications. ERG components elicited by light increments and decrements can be separated using a long-flash paradigm in which periods of light ON and OFF are alternated. Here, the ON-OFF ERG is combined with a silent substitution ...
Cooper Bonnie - - 2014
Here we test interactions of luminance and chromatic input to spatial hyperacuity mechanisms. First, we tested alignment of luminance and chromatic gratings matched or mismatched in contrast polarity or grating type. Thresholds with matched gratings were low while all mismatched pairs were elevated. Second, we determined alignment acuity as a ...
Vishwanath Dhanraj D University of St. - - 2014
Humans can obtain an unambiguous perception of depth and 3-dimensionality with 1 eye or when viewing a pictorial image of a 3-dimensional scene. However, the perception of depth when viewing a real scene with both eyes is qualitatively different: There is a vivid impression of tangible solid form and immersive ...
Yoshizawa Susumu S Atmosphere and Ocean Research Institute, University of Tokyo, Chiba 277-8564 - - 2014
Light-activated, ion-pumping rhodopsins are broadly distributed among many different bacteria and archaea inhabiting the photic zone of aquatic environments. Bacterial proton- or sodium-translocating rhodopsins can convert light energy into a chemiosmotic force that can be converted into cellular biochemical energy, and thus represent a widespread alternative form of photoheterotrophy. Here ...
Diomede Luisa L Department of Molecular Biochemistry and Pharmacology, IRCCS-Istituto di Ricerche Farmacologiche "Mario Negri", Milan, - - 2014
Poor prognosis and limited therapeutic options characterize immunoglobulin light chain (AL) amyloidosis with major heart involvement. Reliable experimental models are needed to study light chains (LC)-heart interactions and to explore strategies for prevention of cardiac damage. We have exploited the nematode C. elegans as a novel tool, since its pharynx ...
Hutson Joel David JD Department of Biological Sciences, Northern Illinois University, DeKalb, - - 2014
A recent study hypothesized that avian-like wrist folding in quadrupedal dinosaurs could have aided their distinctive style of locomotion with semi-pronated and therefore medially facing palms. However, soft tissues that automatically guide avian wrist folding rarely fossilize, and automatic wrist folding of unknown function in extant crocodilians has not been ...
Rane Swati S Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, TN, USA. Electronic address: - - 2014
While spontaneous BOLD fMRI signal is a common tool to map functional connectivity, unexplained inter- and intra-subject variability frequently complicates interpretation. Similar to evoked BOLD fMRI responses, spontaneous BOLD signal is expected to vary with echo time (TE) and corresponding intra/extravascular sensitivity. This may contribute to discrepant conclusions even following ...
Li Bo B Key Laboratory of Magnetic Resonance in Biological Systems and State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China; University of the Chinese Academy of Sciences, Beijing 100049, - - 2014
Blood oxygenation level dependent functional magnetic resonance imaging (BOLD-fMRI), one of the most powerful technologies in neuroscience, measures neural activity indirectly. Therefore, systematical correlation of BOLD signals with other neural activity measurements is critical to understand and then to use the technology. Numerous studies have revealed that the BOLD signal ...
Scheinost D D Department of Diagnostic Radiology, Yale University, New Haven, CT. Electronic address: - - 2014
We present a novel method for controlling the effects of group differences in motion on functional connectivity studies. Resting-state functional magnetic resonance imaging (rs-fMRI) is a powerful tool that allows for the assessment of whole-brain functional organization across a wide range of clinical populations. However, as highlighted by recent studies, ...
Hamamé Carlos M CM Lyon Neuroscience Research Center, Brain Dynamics and Cognition Team, INSERM U1028, CNRS UMR5292, Lyon, France; University Lyon 1, Lyon, France; Laboratoire de Psychologie Cognitive, CNRS UMR6146, Aix-Marseille Université, Marseille, France. Electronic address: - - 2014
Eye movements are a constant and essential component of natural vision, yet, most of our knowledge about the human visual system comes from experiments that restrict them. This experimental constraint is mostly in place to control visual stimuli presentation and to avoid artifacts in non-invasive measures of brain activity, however, ...
Jin Honglei H State Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, 510275 Guangzhou, People's Republic of - - 2014
Under high-irradiance conditions, plants must efficiently protect photosystem II (PSII) from damage. In this study, we demonstrate that the chloroplast protein HYPERSENSITIVE TO HIGH LIGHT1 (HHL1) is expressed in response to high light and functions in protecting PSII against photodamage. Arabidopsis thaliana hhl1 mutants show hypersensitivity to high light, drastically ...
Biswas Atanu A Chemistry Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata-700032, West Bengal, India. - - 2014
Micropatterned surfaces with Tris-NTA and biotin functionalities both in the same micropattern as well as individually in adjacent micropatterns are generated by UV light illumination through photo-masks. These surfaces are extremely useful for the immobilization of oligohistidine and biotin tagged multiple biomolecules/proteins.
Wang Hui H Nano-organic Photoelectronic Laboratory and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of - - 2014
Integrating vertically aligned nanowires (NWs) on a functional substrate is important for the application of NWs in wafer scale assemblies and functional devices. However, vertically aligned NWs via the current epitaxial growth route can only be prepared on crystalline wafers. A convenient method is thus presented to overcome NW substrate ...
Huster René J RJ Experimental Psychology Lab, Carl von Ossietzky University, Oldenburg, Germany; Research Center Neurosensory Science, Carl-von-Ossietzky University Oldenburg, Oldenburg, Germany. Electronic address: - - 2014
Behavioral inhibition often is studied by comparing the electroencephalographic responses to stop and to go signals. Most studies simply assess amplitude differences of the N200 and P300 event-related potentials, which seem to best correspond to increased activity in the theta and delta frequency bands, respectively. However, neither have reliable indicators ...
Fernandez de Castro Juan J University of Louisville, Louisville, 40202, United - - 2014
Purpose. Human and swine retinas have morphological and functional similarities. In the absence of primate models, the swine is an attractive model to study retinal function and disease, with its cone rich visual streak, our ability to manipulate their genome, and the differences in susceptibility of rod and cone photoreceptors ...
Scott Patrick A PA Department of Ophthalmology and Visual Sciences, University of Louisville, 301 East Muhammad Ali Blvd, Louisville, KY, 40202, United - - 2014
Purpose: Functional studies have detected deficits in retinal signaling in asymptomatic children from families with inherited autosomal dominant retinitis pigmentosa (RP). Whether retinal abnormalities are present earlier during gestation or shortly after birth in a subset of children with autosomal dominant RP is unknown and no appropriate animal RP model, ...
Amaral Fernanda G FG Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of São Paulo, - - 2014
Internal temporal organization properly synchronized to the environment is crucial for health maintenance. This organization is provided at the cellular level by the molecular clock, a macromolecular transcription-based oscillator formed by the clock and the clock-controlled genes that is present in both central and peripheral tissues. In mammals, melanopsin in ...
den Dunnen Johan T JT Human and Clinical Genetics, Leiden University Medical Center, Leiden, - - 2014
Currently, we use the term "pathogenicity" to indicate whether a variant in a gene has an influence on the phenotype or not. Since this term is confusing, not neutral, and incorrectly refers to a disease state, it seems better to use a more neutral term. The suggestion is to use ...
Beurskens Rainer R Department of Kinesiology & Health Education, University of Texas, Austin, TX 78712, - - 2014
Lower limb amputation substantially disrupts motor and proprioceptive function. People with lower limb amputation experience considerable impairments in walking ability, including increased fall risk. Understanding the biomechanical aspects of the gait of these patients is crucial in improving their gait function and their quality of life. In the present study, ...
Hariadi Rizal F RF Department of Cell and Developmental Biology, Department of Biophysics, and Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI - - 2014
The molecular motor myosin teams up to drive muscle contraction, membrane traffic, and cell division in biological cells. Myosin function in cells emerges from the interaction of multiple motors tethered to a scaffold, with surrounding actin filaments organized into 3D networks. Despite the importance of myosin function, the influence of ...
Chow James C JC Department of Orthopaedic Surgery, M/C 844, University of Illinois at Chicago, 835 S. Wolcott Avenue, Chicago, IL 60612-3748 - - 2014
The A2 and A4 pulleys have been shown to be important in finger flexor tendon function. Other authors have suggested either reconstruction or venting of portions of these pulleys in an attempt to preserve finger function in certain clinical situations. This study examines the effects of partial incision of these ...
Talagala Dumidu S DS Research School of Engineering, College of Engineering and Computer Science, Australian National University, Canberra, Australia Capital Territory 0200, - - 2014
The spectral localization cues contained in the head-related transfer function are known to play a contributory role in the sound source localization abilities of humans. However, existing localization techniques are unable to fully exploit this diversity to accurately localize a sound source. The availability of just two measured signals complicates ...
Roverud Elin E Department of Speech, Language, and Hearing Sciences, Purdue University, West Lafayette, Indiana - - 2014
The mechanisms of forward masking are not clearly understood. The temporal window model (TWM) proposes that masking occurs via a neural mechanism that integrates within a temporal window. The medial olivocochlear reflex (MOCR), a sound-evoked reflex that reduces cochlear amplifier gain, may also contribute to forward masking if the preceding ...
Schwarzkopf Manti M 1 Technische Universitat Munchen, Lehrstuhl fur - - 2014
Cyanobacteria combine the photosynthetic and respiratory electron transport in one membrane system, the thylakoid membrane. This feature requires an elaborate regulation mechanism to maintain a certain redox status of the electron transport chain, hence, allowing proper photosynthetic and respiratory energy metabolism. In this context, metabolic adaptations, as seen in the ...
Wininger Michael M 1Prosthetics & Orthotics Program, University of Hartford, West Hartford, CT, - - 2014
Background:At the age of 18 years, jazz guitarist Django Reinhardt (1910-1953) sustained significant burns to his left-hand ring and little fingers; yet, subsequently, he relearned to play and achieved international fame, despite his injuries.Case description and methods:Archive film footage and novel motion analysis software were used to compare movements of ...
Luo Xin X Department of Speech, Language, and Hearing Sciences, Purdue University, 500 Oval Drive, West Lafayette, IN 47907, USA. Electronic address: - - 2014
Native Mandarin normal-hearing (NH) listeners can easily perceive lexical tones even under conditions of great voice pitch variations across speakers by using the pitch contrast between context and target stimuli. It is however unclear whether cochlear implant (CI) users with limited access to pitch cues can make similar use of ...
Schatz Andreas A Centre for Ophthalmology, University of Tübingen, Tübingen, Germany; Department of Ophthalmology, Katharinenhospital Stuttgart, Stuttgart, Germany. Electronic address: - - 2014
As impaired S-cone function has been reported psychophysically this study assessed S-cone function during high altitude exposure using electroretinography (ERG) and investigated a possible association with severity of acute mountain sickness (AMS). This work is related to the Tübingen High Altitude Ophthalmology (THAO) study. Standard ERG equipment was used (Diagnosys ...
Pino F F Laboratorio de Fisica Nuclear, Universidad Simon Bolivar, Apartado 89000, 1080A Caracas, Venezuela. Electronic address: - - 2014
The light output response and the neutron and gamma-ray detection efficiency are determined for liquid scintillator EJ-309. The light output function is compared to those of previous studies. Experimental efficiency results are compared to predictions from GEANT4, MCNPX and PENELOPE Monte Carlo simulations. The differences associated with the use of ...
Huarte Alicia - - 2014
Custom Sound EP™ (CSEP) is an advanced flexible software tool dedicated to recording of electrically evoked compound action potentials (ECAPs) in Nucleus(®) recipients using Neural Response Telemetry™ (NRT™). European multi-centre studies of the Freedom™ cochlear implant system confirmed that CSEP offers tools to effectively record ECAP thresholds, amplitude growth functions, ...
Stockman Andrew A Institute of Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL, United - - 2014
Purpose: In this study, we characterize and model changes in visual performance associated with a Tyr99Cys substitution in the guanylate cyclase activating protein (GCAP1) in four family members aged between 39 and 55 years. Guanylate cyclase and its activating protein are molecules in the visual transduction pathway that restore cyclic ...
Romaní Anna M AM Group of Continental Aquatic Ecology, Institute of Aquatic Ecology, University of - - 2014
Biofilms are dynamic players in biogeochemical cycling in running waters and are subjected to environmental stressors like those provoked by climate change. We investigated whether a 2°C increase in flowing water would affect prokaryotic community composition and heterotrophic metabolic activities of biofilms grown under light or dark conditions. Neither light ...
Tochitsky Ivan I Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, - - 2014
Retinitis pigmentosa (RP) and age-related macular degeneration (AMD) are blinding diseases caused by the degeneration of rods and cones, leaving the remainder of the visual system unable to respond to light. Here, we report a chemical photoswitch named DENAQ that restores retinal responses to white light of intensity similar to ...
Huang Wei Chieh WC Department of Ophthalmology, Perelman School of Medicine at the University of Pennsylvania, Scheie Eye Institute, Philadelphia, PA, 19104, United - - 2014
ABSTRACT PURPOSE. To investigate in vivo inner and outer retinal microstructure and effects of structural abnormalities on visual function in patients with retinal degeneration caused by ABCA4 mutations (ABCA4-RD). METHODS. Patients with ABCA4-RD (n=45; age range, 9-71 years) were studied by spectral-domain optical coherence tomography (OCT) scans extending from the ...
Pierce Russell S RS Visual Cognition and Human Performance Laboratory, Department of Psychology, University of California, Riverside, United States of America. Electronic address: - - 2014
In the present study we assessed whether the limits in visual-spatial attention associated with aging affect the spatial extent of attention in depth during driving performance. Drivers in the present study performed a car-following and light-detection task. To assess the extent of visual-spatial attention, we compared reaction times and accuracy ...
Pinheiro M B MB Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil - - - 2014
Background: Respiratory muscular weakness and associated changes in thoracoabdominal motion have been poorly studied in stroke subjects, since the individuals' functional levels were not previously considered in the investigations. Aim: To investigate the breathing patterns, thoracoabdominal motion, and respiratory muscular strength in chronic stroke subjects, who were stratified into two ...
Pan Xiaoyang X State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou, 350002, P.R. China. - - 2014
Zinc oxide (ZnO) nanostructured materials have received significant attention because of their unique physicochemical and electronic properties. In particular, the functional properties of ZnO are strongly dependent on its morphology and defect structure, particularly for a semiconductor ZnO-based photocatalyst. Here, we demonstrate a simple strategy for simultaneous morphology control, defect ...
Barneche Fredy F Environmental and Evolutionary Genomics Section, Ecole Normale Supérieure, Institut de Biologie de l'ENS, IBENS, Paris, F-75005 - - 2014
Research on the functional properties of nucleosome structure and composition dynamics has revealed that chromatin-level regulation is an essential component of light signalling and clock function in plants, two processes that rely extensively on transcriptional controls. In particular, several types of histone post-translational modifications and chromatin-bound factors act sequentially or ...
1 2 3 4 5 6 7 8 9 10 >