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Spielberg Leigh H - - 2013
Light-chain deposition disease (LCDD) is a rare condition characterised by deposition of monoclonal immunoglobulin light chains (LCs) in tissues, resulting in varying degrees of organ dysfunction. This study reports the characteristic clinical ocular findings seen in advanced LCDD upon development of ocular fundus changes. This is the first report to ...
Garrido-Ríos Anastasia Alejandra - - 2013
Depilation techniques have gain popularity in the last few decades. Nowadays there are available a wide variety of lasers as well as intense pulsed light for depilation. However, little is known about the long-term effects of these procedures when melanocytic nevi are affected by them. We report the cases of ...
Menchini Giovanni - - 2013
Efforts have been recently made to investigate simple, objective, accurate, and reproducible methods of clinical/noninvasive assessment of nonsegmental vitiligo. However, studies have mostly considered quantitative or semiquantitative parameters, almost neglecting the purely qualitative appearance of vitiligo lesions at a given moment and over time. The objective of this study was ...
Nagendran Sonali T - - 2013
Flashing lights (photopsia) and floaters are common visual phenomena and patients frequently present to hospital with these symptoms. This article provides a guide for the non-specialist to the different pathologies that may result in photopsia and floaters.
Vitório Rodrigo - - 2013
The purpose of the current study was to investigate the role of visual information on gait control in people with Parkinson's disease as they crossed over obstacles. Twelve healthy individuals, and 12 patients with mild to moderate Parkinson's disease, walked at their preferred speeds along a walkway and stepped over ...
Tan Christine M CM Department of Psychology, University of Essex, Colchester, CO4 3SQ, - - 2013
Tinnitus is strongly linked with the presence of damaged hearing. However, it is not known why tinnitus afflicts only some, and not all, hearing-impaired listeners. One possibility is that tinnitus patients have specific inner ear damage that triggers tinnitus. In this study, differences in cochlear function inferred from psychophysical measures ...
Manganelli Fiore - - 2013
Processing of time in the millisecond range seems to depend on cerebellar function and it can be assessed by using the somatosensory temporal discrimination threshold testing. No studies have yet investigated this temporal discrimination task in patients with cerebellar atrophy. Eleven patients with degenerative cerebellar ataxia and 11 controls underwent ...
McAnany J Jason - - 2013
ABSTRACT Purpose: To document a novel NYX gene mutation in a patient with X-linked complete congenital stationary night blindness and to describe this patient's electroretinogram (ERG) characteristics. Methods: ERGs were recorded from a 17-year-old male with a previously unreported NYX mutation (819G > A) that results in a missense codon change (Trp237Ter). ...
Ma Zong-Min ZM National Key Laboratory for Electric Measurement Technology, North University of China, No, 3, Xue Yuan Road, TaiYuan, Shanxi 030051, China. - - 2013
In this paper, the potential sensitivity in Kelvin probe force microscopy (KPFM) was investigated in frequency modulation (FM) and heterodyne amplitude modulation (AM) modes. We showed theoretically that the minimum detectable contact potential difference (CPD) in FM-KPFM is higher than in heterodyne AM-KPFM. We experimentally confirmed that the signal-to-noise ratio ...
Li Guang - - 2013
To provide an alternative device for immobilization of the head while easing claustrophobia and improving comfort, an "open-face" thermoplastic mask was evaluated using video-based optical surface imaging (OSI) and kilovoltage (kV) X-ray radiography. A three-point thermoplastic head mask with a precut opening and reinforced strips was developed. After molding, it ...
Rabuffetti Marco - - 2013
In the present study we explored the effect of prismatic adaptation (PA) applied to the upper right limb on the walking trajectory of a neglect patient with more severe neglect in far than in near space. The patient was asked to bisect a line fixed to the floor by walking ...
Poshusta Tanya L TL Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA. - - 2013
Light chain (AL) amyloidosis is a devastating disease characterized by amyloid deposits formed by immunoglobulin light chains. Current available treatments involve conventional chemotherapy and autologous stem cell transplant. We have recently concluded a phase III trial comparing these two treatments. AL amyloidosis patients who achieve hematological complete response (CR) do ...
Roach B J BJ Northern California Institute for Research and Education, San Francisco, CA 94121, - - 2013
In electroencephalogram (EEG) studies of auditory steady-state responses (ASSRs), patients with schizophrenia show a deficit in power and/or phase-locking, particularly at the 40 Hz frequency where these responses resonate. In addition, studies of the transient gamma-band response (GBR) elicited by single tones have revealed deficits in gamma power and phase-locking ...
Ozerdema Ayşegül - - 2013
This report presents six cardinal results obtained with methods of oscillatory brain dynamics in euthymic and manic bipolar patients in comparison to healthy controls. Measurements include changes in oscillatory response activities in the theta, alpha, beta, and gamma frequency ranges. The analysis shows that spontaneous and response activities in the ...
Ishak Wan Syafira - - 2013
The general consensus on the roles of hearing loss in triggering tinnitus seems not applicable in patients with normal hearing thresholds. The absence of hearing loss on the audiogram in this group of patients poses a serious challenge to the cochlear theories in explaining tinnitus generation in this group of ...
Pataky Todd C TC Department of Bioengineering, Shinshu University, Ueda, Nagano, - - 2013
During power grasp, the number of local force maxima reflects either the central nervous system's preferential use of particular hand regions, or anatomical constraints, or both. Previously, both bimodal and trimodal force maxima have been hypothesized for power grasp of a cylindrical handle. Here we measure the number of local ...
Johnson J Michael JM Center for Musculoskeletal Research, University of Tennessee, 301 Perkins Hall, Knoxville, TN 37996, - - 2013
Current clinical evaluations often rely on static anatomic imaging modalities for diagnosis of mechanical low back pain, which provide anatomic snapshots and a surrogate analysis of a functional disease. Three dimensional in vivo motion is available with the use of digital fluoroscopy, which was used to capture kinematic data of ...
Grozdanic Sinisa D - - 2012
Objective  To develop fast and reliable testing routines for diagnosing retina and optic nerve diseases in canine cataract patients based on chromatic properties of the pupillary light reflex response. Procedures  Seventy-seven canine patients with a history of cataract and decreased vision (43 patients with cataracts and no evidence of retina ...
Fabijańska Anna - - 2012
The aim of this study was to evaluate distortion product otoacoustic emissions (DPOAEs) and extended high-frequency (EHF) thresholds in a control group and in patients with normal hearing sensitivity in the conventional frequency range and reporting unilateral tinnitus. Seventy patients were enrolled in the study: 47 patients with tinnitus in ...
Sharma Vinod Kumar - - 2012
Photodermatoses are a group of skin diseases primarily caused by, or exacerbated by exposure to ultraviolet and or visible radiation. The effect of sunlight on skin depends on a number of factors including skin colour, skin phototype and the content and type of melanin in the skin. There are only ...
Monaghan Gail M - - 2012
The biomechanical mechanisms that link foot structure to injuries of the musculoskeletal system during gait are not well understood. This study had two parts. The purpose of part one was to determine the relation between clinical rearfoot and forefoot angles and foot angles as they make contact with the ground. ...
Trivelli M - - 2012
The aim of the present study is to measure sound sensitivity of the saccule for low frequencies in a population of both young and adult prelingual deaf patients using cervical Vestibular Evoked Myogenic Potentials (cVEMPs) and to correlate the findings obtained with the phonological features. The sensitivity of the saccule ...
Hong Jong Soo - - 2012
Various methods of photodynamic therapy (PDT) for acne have been introduced. However, comparative studies among them are still needed. We performed this study to compare the effect of methyl aminolevulinate (MAL) PDT for acne between red light and intense pulsed light (IPL). Twenty patients were enrolled in this eight-week, prospective, ...
Su Zhong - - 2012
Purpose: To analyze prostate intrafraction motion using both non-gas-release (NGR) and gas-release (GR) rectal balloons and to evaluate the ability of GR rectal balloons to reduce prostate intrafraction motion.Methods: Twenty-nine patients with NGR rectal balloons and 29 patients with GR balloons were randomly selected from prostate patients treated with proton ...
Park Justin C - - 2012
Purpose: Understanding motion characteristics of liver such as, interfractional and intrafractional motion variability, difference in motion within different locations in the organ, and their complex relationship with the breathing cycles are particularly important for image-guided liver SBRT. The purpose of this study was to investigate such motion characteristics based on ...
Zhu Mingyao M Department of Radiation Oncology, Washington University School of Medicine, Saint Louis, MO 63110, - - 2013
Using real-time electromagnetic (EM) transponder tracking data recorded by the Calypso 4D Localization System, we report inter- and intrafractional target motion of the prostate bed, describe a strategy to evaluate treatment adequacy in postprostatectomy patients receiving intensity modulated radiation therapy (IMRT), and propose an adaptive workflow. Tracking data recorded by ...
Mroczkowska Stephanie - - 2012
Purpose:  To investigate the coexistence of ocular microvascular and systemic macrovascular abnormalities in early stage, newly diagnosed and previously untreated normal tension glaucoma patients (NTG). Methods:  Retinal vascular reactivity to flickering light was assessed in 19 NTG and 28 age-matched controls by means of dynamic retinal vessel analysis (IMEDOS GmbH, ...
Ryu In Sun - - 2012
OBJECTIVE: To verify that tinnitus itself could disturb speech perception and to evaluate the effects of masking noise on speech perception ability in the patients with normal hearing but unilateral chronic tinnitus using the hearing in noise test. STUDY DESIGN: Prospective, nonrandomized study. MATERIALS AND METHODS: Between June 2009 and ...
Bani Monireh Ahmadi - - 2012
Background: Mechanical orthoses are used for standing and walking after neurological injury. Most orthoses such as the advanced reciprocating gait orthosis typically use solid ankle-foot orthoses.Objectives: The goal of this study was to test the effects of ankle dorsiflexion assistance in patients with spinal cord injury when ambulating with an ...
De Sá Teixeira Nuno - - 2012
When people are shown a moving object that suddenly disappears and are instructed to locate its vanishing position, systematic errors in the direction of motion and in the direction of gravity are usually observed. Entitled, respectively, Representational Momentum (RepMo) and Representational Gravity, these phenomena seem to be influenced by low-level ...
Godara Pooja P Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI, - - 2012
To examine retinal structure and changes in photoreceptor intensity after dark adaptation in patients with complete congenital stationary night blindness and Oguchi disease. Prospective, observational case series. We recruited 3 patients with complete congenital stationary night blindness caused by mutations in GRM6, 2 brothers with Oguchi disease caused by mutations ...
Rong Panying - - 2012
A multimodal approach combining acoustics, intelligibility ratings, articulography and surface electromyography was used to examine the characteristics of dysarthria due to cerebral palsy (CP). CV syllables were studied by obtaining the slope of F2 transition during the diphthong, tongue-jaw kinematics during the release of the onset consonant, and the related ...
Schardt Dieter - - 2012
Light flashes (phosphenes) are reported by most of the astronauts during spaceflight and patients treated with radiotherapy for brain tumors. They are induced by cosmic ray traversals, but the target area is unknown. With a correlation analysis of the visual sensation and the position of the beam in patients treated ...
Rosenfelder Nicola Abigail NA Department of Clinical Oncology, Royal Marsden NHS Foundation Trust, London, United Kingdom. Electronic address: - - 2013
Prospectively compare patient setup accuracy and intrafraction motion of a standard 3-point thermoplastic mask with the Gill-Thomas-Cosman relocatable stereotactic frame, during fractionated cranial radiation therapy using the ExacTrac system (Brainlab AG Feldkirchen, Germany) for daily online correction. The number of fractions with all postcorrection and post-treatment errors <2 mm was ...
He Xin - - 2012
The study sample consisting of 429 people (207 males, 222 females) of Han nationality in Shaanxi, China. Five types of tongue movements were investigated, including tongue rolling, tongue folding, tongue twisting, pointed tongue and clover-leaf tongue. The results revealed that the frequencies of tongue rolling, tongue folding, tongue twisting, pointed ...
Chen Yi-An - - 2013
A mild, micropapular eruption previously coined as "solar dermatitis" on the extensor of the forearm is a common form of photodermatitis in Taiwan. This study aimed to investigate the clinicopathologic findings of "solar dermatitis", the micropapular type of photodermatitis. We characterized the features of this photodermatitis by retrospectively reviewing and ...
Crary Michael A - - 2012
Spontaneous swallowing is considered a reflexive, pharyngeal clearance mechanism. Reductions in spontaneous swallow frequency may be a sensitive index for dysphagia and related morbidities. This study evaluated an acoustic recording technique as a measure to estimate spontaneous swallow frequency. Initially, a multichannel physiologic (surface electromyography, swallow apnea, cervical auscultation) recording ...
Lamesch Sylvain - - 2012
The impact that vowels have on the variation across voice range profiles (VRPs) is studied along with three factors: fundamental frequency, singer's gender, and laryngeal vibratory mechanism used to sing. VRPs of 21 advanced singers were established by recording, in separate takes, vocal productions using laryngeal vibratory mechanisms M1 and ...
Valentine Susie - - 2012
PURPOSE: To determine whether reduced audible bandwidth associated with hearing loss contributes to difficulty benefiting from an onset asynchrony between sounds. METHOD: Synthetic double-vowel identification was measured for normal-hearing listeners and listeners with hearing loss. One vowel (target 2) was 250 ms in duration and one (target 1) varied in ...
Tanaka N - - 2012
Summary  Disuse atrophy of swallowing-related organs is suspected when decreased swallowing frequency is seen in the elderly. However, swallowing frequency has not been examined in elderly people during daily life. We developed a swallowing frequency meter containing a laryngeal microphone that does not restrict the subject's ability to perform daily ...
Awan Shaheen N - - 2012
The purpose of this study was to specifically examine the effects of vocal loudness/intensity condition and vowel type on cepstral analysis measurements. Experimental, mixed design. Sustained vowel samples of /i/, /ɑ/, /u/, and /æ/ were elicited from 92 healthy male and female subjects between the ages of 18 and 30 ...
Lee Wai-Sum - - 2012
The study investigates the quantal nature of two sets of Cantonese point vowels, the long [i: u:] in CV open syllables and the medium-long [i u] in CVS closed syllables, where S = stop consonant, by determining the articulatory-acoustic relations in the production of the four Cantonese point vowels. It ...
Cho Sandy - - 2012
This study contrasts the production of Cantonese words between native (Hong Kong) immigrant speakers of the language and native first or second generation American-born Cantonese speakers. The word lists were constructed to sample across the tone space and vowel space. Multiple recordings were recorded at different intervals in order to ...
Derrick Donald - - 2012
This research demonstrates that North American English speakers with faster syllable iterance rates are more likely to produce reduced /t/ and /d/ as taps, which have two directions of motion, than flaps, which have one. Using B/M mode ultrasound to capture tongue motion direction, coupled acoustic recordings to capture syllable ...
Reichard Rachel - - 2012
There are two ways to produce an `s' in English: apical and laminal. They are almost identical perceptually and the reason for choosing one type is not well understood. This study questions whether one type is preferred in certain conditions, such as high vs low palate height or in post ...
Chang Charles - - 2012
This study presents a detailed acoustic characterization of the contrast between the two voiceless coronal fricatives of Korean, variously described in the literature as a lenis/fortis or aspirated/fortis contrast. In utterance-initial position, the fricatives were found to differ in centroid frequency, frication duration, aspiration duration, following vowel duration, and several ...
Dhananjaya N - - 2012
In this paper, the acoustic-phonetic characteristics of steady apical trills-trill sounds produced by the periodic vibration of the apex of the tongue-are studied. Signal processing methods, namely, zero-frequency filtering and zero-time liftering of speech signals, are used to analyze the excitation source and the resonance characteristics of the vocal tract ...
Matuz Tamara T Institute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Germany. - - 2012
In this study we aimed to develop a habituation paradigm that allows the investigation of response decrement and response recovery and examine its applicability for measuring the habituation of the visually evoked responses (VERs) in neonatal and fetal magnetoencephalographic recordings. Two paradigms, one with a long and one with a ...
Humbert Ianessa A IA Department of Physical Medicine and Rehabilitation, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA. - - 2012
Before a bolus is pushed into the pharynx, oral sensory processing is critical for planning movements of the subsequent pharyngeal swallow, including hyoid bone and laryngeal (hyo-laryngeal) kinematics. However, oral and pharyngeal sensory processing for hyo-laryngeal kinematics is not fully understood. In 11 healthy adults, we examined changes in kinematics ...
Russell T - - 2012
Laryngoscopy can induce stress responses that may be harmful in susceptible patients. We directly measured the force applied to the base of the tongue as a surrogate for the stress response. Force measurements were obtained using three FlexiForce Sensors(®) (Tekscan Inc, Boston, MA, USA) attached along the concave surface of ...
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