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Preuß Annegret A Department of Physics, Humboldt - Universität zu Berlin, Newtonstraße 15, 12489 Berlin, Germany. Electronic address: - - 2014
The photodynamic effect, originally used in photodynamic therapy (PDT) for the treatment of different diseases, e.g. of cancer, has recently been introduced for the inactivation of bacteria. Mold fungi, which provoke health problems like allergies and diseases of the respiratory tract, are even more resistant and their biology is also ...
Pruß Sonja S Karlsruhe Institute of Technology (KIT) - South Campus, Institute for Applied Biosciences, Dept. of Microbiology, Hertzstrasse 16, D-76187 Karlsruhe, - - 2014
Alternaria alternata is a filamentous fungus that causes considerable loss of crops of economically important feed and food worldwide. It produces more than 60 different secondary metabolites among which alternariol (AOH) and altertoxin (ATX) are the most important mycotoxins. We found that mycotoxin production and spore formation are regulated by ...
Trauth Stephanie S Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg, Germany; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, - - 2014
Fluorescent protein promoter reporters are important tools that are widely used for diverse purposes in microbiology, systems biology and synthetic biology and considerable engineering efforts are still geared at improving the sensitivity of the reporter systems. Here we focus on dark noise, i.e. the signal that is generated by the ...
Hardeman Lotte C LC Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 114, 3584 CM Utrecht, The - - 2013
In the treatment of laminitis, reducing deep digital flexor muscle (DDFM) activity might diminish its pull on the distal phalanx, thereby preventing displacement and providing pain relief. Injection of Clostridium botulinum toxin type A into the DDFM of horses is potentially therapeutic. However, the effects of C. botulinum toxin type ...
Heimer-McGinn Victoria V School of Biochemistry and Cell Biology, University College Cork, Cork, Ireland; Department of Cognitive, Linguistic and Psychological Sciences, Brown University, Providence, RI 02912, USA. Electronic address: - - 2013
Tetanus toxin light chain has been used for some time as a genetically-encoded tool to inhibit neurotransmission and thereby dissect mechanisms underlying neural circuit formation and function. In addition to cleaving v-SNARE proteins involved in axonal neurotransmitter release, tetanus toxin light chain can also block activity-dependent dendritic exocytosis. The application ...
Baysal Ayse Handan - - 2013
In the present study, the effect of short wave ultraviolet light (UV-C) on the inactivation of Alicyclobacillus acidoterrestris DSM 3922 spores in commercial pasteurized white grape and apple juices was investigated. The inactivation of A. acidoterrestris spores in juices was examined by evaluating the effects of UV light intensity (1.31, ...
Turpin Alex - - 2013
Type I and type II second harmonic generation (SHG) of a beam transformed by the conical refraction phenomenon are presented. We show that, for type I, the second harmonic intensity pattern is a light ring with a point of null intensity while, for type II, the light ring possesses two ...
Murdoch L E - - 2013
This study assessed the effects of high-intensity violet light on selected yeast and mould fungi. Cell suspensions of Saccharomyces cerevisiae, Candida albicans, and dormant and germinating spores (conidia) of the mould Aspergillus niger were exposed to high-intensity narrow band violet light with peak output at 405 nm generated from a light-emitting ...
Rutala William A - - 2013
We tested the ability of an ultraviolet C (UV-C)-reflective wall coating to reduce the time necessary to decontaminate a room using a UV-C-emitting device (Tru-D SmartUVC). The reflective wall coating provided the following time reductions for decontamination: for methicillin-resistant Staphylococcus aureus, from 25 minutes 13 seconds to 5 minutes 3 ...
Guan Jiewen - - 2013
This study evaluated the influence of temperature and organic load on the effectiveness of domestic bleach (DB), Surface Decontamination Foam (SDF), and Virkon in inactivating Geobacillus stearothermophilus spores, which are a surrogate for Bacillus anthracis spores. The spores were suspended in light or heavy organic preparations and the suspension was ...
O'Malley Sean - - 2013
A novel method for applying high-throughput docking to challenging metalloenzyme targets is described. The method utilizes information-based virtual transformation of library carboxylates to hydroxamic acids prior to docking, followed by compound acquisition, one-pot (two steps) chemical synthesis and in vitro screening. In two experiments targeting the botulinum neurotoxin serotype A ...
Marmottant Philippe - - 2013
Equisetum plants (horsetails) reproduce by producing tiny spherical spores that are typically 50 µm in diameter. The spores have four elaters, which are flexible ribbon-like appendages that are initially wrapped around the main spore body and that deploy upon drying or fold back in humid air. If elaters are believed ...
St Denis Tyler G TG Department of Chemistry, Columbia University, New York, NY, - - 2013
This article is a highlight of the study by Maclean et al. in this issue of Photochemistry and Photobiology describing the sporicidal effects 405 nm visible light alone on endospores of the Clostridium and Bacillus genera. 1.73 kJ cm(-2) was capable of reducing endospore colony-forming units by up to 4-log(10). ...
Berstad Maria Brandal - - 2012
Photochemical internalization (PCI) is a modality for cytosolic release of drugs trapped in endocytic vesicles. The method is based upon photosensitizers localized in the membranes of endocytic vesicles which create membrane rupture upon light exposure by generating reactive oxygen species (ROS), predominantly singlet oxygen ((1)O(2)). The human epidermal growth factor ...
Banerjee Indrani - - 2012
AIM: The objective of this study was to develop porphyrin-based formulations to inactivate Bacillus spores. We probed the effect of porphyrins alone and in combination with germinants against both Bacillus cereus and B. anthracis spores in the presence of light. METHODS AND RESULTS: We tested the effect of two different ...
Parapatits Lukas - - 2012
A Steiner type formula for continuous translation invariant Minkowski valuations is established. In combination with a recent result on the symmetry of rigid motion invariant homogeneous bivaluations, this new Steiner type formula is used to obtain a family of Brunn-Minkowski type inequalities for rigid motion intertwining Minkowski valuations.
Rossi Tommaso - - 2012
Knowledge of vitreous motion in response to saccades is a prerequisite for understanding vitreous rheology. Purpose of present paper is to introduce Ultrasound Image Velocimetry of the human eye, measure scleral and vitreous velocity fields and test the reproducibility of the proposed technique. Twelve patients with varying diagnosis underwent Ocular ...
Babiloni Claudio - - 2011
It has been shown that frontocentral electroencephalographic (EEG) alpha rhythms (about 10-12Hz) were higher in amplitude in expert golfers in successful than unsuccessful putts, possibly reflecting the idea that amplitude regulation of frontocentral alpha rhythms is a physiological mechanism implied in motor control and golfer's performance (Babiloni et al., 2008). ...
Meister David W - - 2011
The purpose of this study was to determine biomechanical factors that may influence golf swing power generation. Three-dimensional kinematics and kinetics were examined in 10 professional and 5 amateur male golfers. Upper-torso rotation, pelvic rotation, X-factor (relative hip-shoulder rotation), O-factor (pelvic obliquity), S-factor (shoulder obliquity), and normalized free moment were ...
Yun Dongwon - - 2011
In this paper, a novel caudal fin for actuating a robotic fish is presented. The proposed caudal fin waves in a vertical direction with a specific spatial shape, which is determined by a so-called shape factor. For a specific shape factor, a traveling wave with a vertical phase difference is ...
Mills Chris - - 2011
This study used a single-subject design to establish a valid and reliable protocol for monitoring soft tissue motion under compression garments during drop landings. One male participant performed six 40cm drop landings onto a force platform, in three compression conditions (none, medium high). Five reflective markers placed on the thigh ...
Lorenzo Danilo De - - 2011
BACKGROUND: Force feedback in robotic minimally invasive surgery allows the human operator to manipulate tissues as if his/her hands were in contact with the patient organs. A force sensor mounted on the probe raises problems with sterilization of the overall surgical tool. Also, the use of off-axis gauges introduces a ...
Chen Wen-Ming - - 2011
Identification of the localized mechanical response of the plantar soft tissue pads underneath the metatarsal heads (i.e., sub-MTH pad) to external loading is key to understand and predict how it functions in a gait cycle. The mechanical response depends on various parameters, such as the external load (direction and rate), ...
Gordon J J JJ Department of Radiation Oncology, Virginia Commonwealth University, PO Box 980058, Richmond, VA 23298, USA. - - 2011
In intensity modulated radiation therapy (IMRT) of cervical cancer, uterine motion can be larger than cervix motion, requiring a larger clinical target volume to planning target volume (CTV-to-PTV) margin around the uterine fundus. This work simulates different motion models and margins to estimate the dosimetric consequences. A virtual study used ...
Muñoz José L P - - 2011
Information regarding melatonin production in molluscs is very limited. In this study the presence and daily fluctuations of melatonin levels were investigated in hemolymph, retina and nervous system-related structures in the cephalopod Octopus vulgaris. Adult animals were maintained in captivity under natural photoperiod and killed at different times in a ...
O'Daly Brendan J - - 2011
This study evaluates high power low frequency ultrasound transmitted via a flat vibrating probe tip as an alternative technology for meniscal debridement in the bovine knee. An experimental force controlled testing rig was constructed using a 20 kHz ultrasonic probe suspended vertically from a load cell. Effect of variation in ...
Foreman Julia - - 2011
Accurate development of the gynoecium, the female reproductive organ, is necessary to achieve efficient fertilization. In Arabidopsis, the correct patterning of the apical-basal axis of the gynoecium requires the establishment of a morphogenic gradient of auxin. This allows the production of specialized tissues, whose roles consist of attracting pollen, allowing ...
Johnsen Sönke - - 2011
Because light in the pelagic environment is partially polarized, it has been suggested that the polarization sensitivity found in certain pelagic species may serve to enhance the contrast of their transparent zooplankton prey. We examined its potential during cruises in the Gulf of Mexico and Atlantic Ocean and at a ...
Castillo Catherine - - 2011
Circadian rhythms are physiological and behavioral oscillations that have period lengths of approximately 24 hours. In mammals, circadian rhythms are driven by a master pacemaker in the hypothalamic suprachiasmatic nucleus (SCN). These rhythms can be entrained to light:dark cycles through photic and non-photic cues. Current research suggests that the SCN ...
Cui Shaoguo - - 2011
Ultrasonic elastography is an imaging technique providing information about the relative stiffness of biological tissues. In general, elastography suffers from noise artifacts, which degrade lesion detectability and increase the likelihood of misdiagnosis. This paper proposes a method called transmit- side frequency compounding for elastography (TSFC). Beamforming is modified to transmit ...
Li Weiyang - - 2011
This paper describes the use of Au nanocages covered with smart, thermally-responsive polymers for controlled release with high-intensity focused ultrasound (HIFU). HIFU is a highly precise medical procedure that uses focused ultrasound to heat and destroy pathogenic tissue rapidly and locally in a non-invasive or minimally invasive manner. The released ...
Bulkin David A - - 2011
We investigated the functional architecture of the inferior colliculus (IC) in rhesus monkeys. We systematically mapped multiunit responses to tonal stimuli and noise in the IC and surrounding tissue of six rhesus macaques, collecting data at evenly placed locations and recording nonresponsive locations to define boundaries. The results show a ...
Tsai Tsung-Yuan - - 2011
Biomechanics of the knee during stair-ascent has mostly been studied using skin-marker-based motion analysis techniques, but no study has reported a complete assessment of the soft tissue artifacts (STA) and their effects on the calculated joint center translation, angles and moments at the knee in normal subjects during this activity. ...
Bourne Roger - - 2011
This study investigates the hypothesis that shallow edge lifting force in high-level rock climbers is more strongly related to fingertip soft tissue anatomy than to absolute strength or strength to body mass ratio. Fifteen experienced climbers performed repeated maximal single hand lifting exercises on rectangular sandstone edges of depth 2.8, ...
Santi Peter A - - 2011
Light sheet fluorescence microscopy (LSFM) functions as a non-destructive microtome and microscope that uses a plane of light to optically section and view tissues with subcellular resolution. This method is well suited for imaging deep within transparent tissues or within whole organisms, and because tissues are exposed to only a ...
Marzec E - - 2011
This paper reports on the effect of paracetamol on the dielectric behavior of the rabbit lens. Measurements were performed over the frequency range of 100 Hz-100 kHz in air and at the temperature of 35°C. The frequency dependencies of the relative permittivity and dielectric loss for the control and paracetamol-control ...
Chen Hong - - 2011
Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. ...
Zhen Shu Jun - - 2011
A novel type of leaf-like poly (p-phenylenediamine) (PpPD) microcrystal was prepared under mild conditions, which was successfully applied to the visual detection of Co(2+)in vitro and in tissue based on the extinction and light scattering features owing to the special etching effect of Co(2+) on the surface of the leaf-like ...
Chen Shing-Jye - - 2011
Background: Soft-tissue movement has challenged the use of noninvasive skin-based markers that are assumed to be rigidly attached to the underlying bony landmarks. We assessed soft-tissue movement in multiple foot segments by calculating the relative changes in the intermarker distances of the hindfoot, midfoot, and forefoot segments during the early, ...
Zañartu Matías M School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907, USA. - - 2011
Different source-related factors can lead to vocal fold instabilities and bifurcations referred to as voice breaks. Nonlinear coupling in phonation suggests that changes in acoustic loading can also be responsible for this unstable behavior. However, no in vivo visualization of tissue motion during these acoustically induced instabilities has been reported. ...
Ellison Cory T - - 2011
The phytohormone ethylene differentially regulates plant architecture and growth in both a light- and nutrient-dependent fashion. The modulation of plant development by ethylene in response to both external and internal signals can also generate tissue-specific differential responses. Here, we report that XAP5 CIRCADIAN TIMEKEEPER (XCT) is involved in blue light-dependent ...
Asavasanti Suvaluk - - 2011
  Pulsed electric fields (PEF) nonthermally induce cell membrane permeabilization and thereby improve dehydration and extraction efficiencies in food plant materials. Effects of electrical field strength and number of pulses on plant tissue integrity have been studied extensively. Two previous studies on the effect of pulse frequency, however, did not ...
Geiser Eveline - - 2010
Auditory metre perception refers to the ability to extract a temporally regular pulse and an underlying hierarchical structure of perceptual accents from a sequence of tones. Pulse perception is widely present in humans, and can be measured by the temporal expectancy for prospective tones, which listeners generate when presented with ...
Vergara Margarita - - 2011
The aim of this work is to determine the influence of multisensory (visual-haptic) integration and the level of interaction (seeing photographs, seeing the actual product, touching it and using it) on the perception of products, including perceived ergonomics. The product selected for the experiment was the hammer, as this will ...
Nakatani Masashi M Graduate School of Information Science and Technology, The University of Tokyo, Bunkyo, Tokyo, Japan. - - 2011
The sense of touch is believed to provide a reliable perception of the object's properties; however, our tactile perceptions could be illusory at times. A recently reported tactile illusion shows that a raised form can be perceived as indented when it is surrounded by textured areas. This phenomenon suggests that ...
Ferrè Elisa Raffaella ER Department of Psychology, University of Pavia, Piazza Botta 6, 27100 Pavia, Italy. - - 2011
Caloric vestibular stimulation (CVS) is a physiological technique demonstrated to transiently improve hemianaesthesia in right brain-damaged patients (Bottini et al. in Exp Brain Res 99(1):164-169, 1994, Nature 376:778-781, 1995, Neurology 65(8):1278-1283, 2005). Recent studies suggest that these effects are based on the anatomical overlapping between vestibular and tactile projections (Bottini ...
Spering Miriam - - 2011
Many neurophysiological studies in monkeys have indicated that visual motion information for the guidance of perception and smooth pursuit eye movements is - at an early stage - processed in the same visual pathway in the brain, crucially involving the middle temporal area (MT). However, these studies left some questions ...
Bogerd Cornelis P - - 2011
We report the effects of full-face motorcycle helmet ventilation systems on heat, airflow, noise, and comfort perception for ventilation changes on the scalp. Eight subjects (aged 28.0 ± 5.4 years) underwent two experimental trials at ambient temperatures of 23.7 ± 0.4°C or 27.5 ± 0.3°C. In each trial, the thermally ...
Tiest Wouter M Bergmann - - 2010
This paper reviews tactual perception of material properties such as roughness, compliance, coldness and friction. Psychophysical functions relating physical properties to perception are discussed, as well as discrimination thresholds. Also, the neural codes mediating some of these sensations are discussed. Furthermore, we take a look into how sensation of these ...
Beets I A M - - 2010
Perception self-evidently affects action, but under which conditions does action in turn influence perception? To answer this question we ask observers to view an ambiguous stimulus that is alternatingly perceived as rotating clockwise or counterclockwise. When observers report the perceived direction by rotating a manipulandum, opposing directions between report and ...
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