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Wu Shasha S Department of Neurology, Adult Epilepsy Center, University of Chicago Medical Center, Chicago, Illinois, - - 2014
To assess the role of ictal baseline shifts (IBS) and ictal high-frequency oscillations (iHFOs) in intracranial electroencephalography (EEG) presurgical evaluation by analysis of the spatial and temporal relationship of IBS, iHFOs with ictal conventional stereo-electroencephalography (icEEG) in mesial temporal lobe seizures (MTLS). We studied 15 adult patients with medically refractory ...
Nucci Paolo P University Eye Clinic, San Giuseppe Hospital, University of Milan, Via San Vittore 12, 20123, Milan, Italy, - - 2014
The cause of the anomalous head posture (AHP) has been mainly assigned to ocular, orthopedic, and neurologic causes. The AHP can take the form of head tilt, face turn, chin up, chin down, or combined, depending on the specific etiology. However, there are many variations, and the type of the ...
Lechner Corinna C Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, - - 2014
Direction changing horizontal positional nystagmus can be observed in a variety of central and peripheral vestibular disorders. We tested sixty subjects with horizontal positional nystagmus and vertigo on the Epley Omniax(®) rotator. Monocular video recordings were performed with the right or left ear down, in the supine and prone positions. ...
Gardiner Stuart K SK Devers Eye Institute, Legacy Research Institute, Portland, Oregon. Electronic address: - - 2014
Visual field testing uses high-contrast stimuli in areas of severe visual field loss. However, retinal ganglion cells saturate with high-contrast stimuli, suggesting that the probability of detecting perimetric stimuli may not increase indefinitely as contrast increases. Driven by this concept, this study examines the lower limit of perimetric sensitivity for ...
Tibbetts Michael D MD Department of Ophthalmology, Tufts Medical Center, Boston, - - 2014
IMPORTANCE Clinical trials indicate that visual impairment is significantly greater in patients receiving ocriplasmin than placebo. The mechanism of this symptom has not been explained. We report a patient with persistent darkening of her vision after intravitreal ocriplasmin and describe ancillary testing findings that may yield insights into the effects ...
Forbes Dorothy D Faculty of Nursing, University of Alberta, level 3, Edmonton Clinic Health Academy, Edmonton, Alberta, Canada, - - 2014
Rest-activity and sleep-wake cycles are controlled by the endogenous circadian rhythm generated by the suprachiasmatic nuclei (SCN) of the hypothalamus. Degenerative changes in the SCN appear to be a biological basis for circadian disturbances in people with dementia, and might be reversed by stimulation of the SCN by light. The ...
Bhole Malini V MV Department of Immunology, Russells Hall Hospital, The Dudley Group NHS Foundation Trust, Dudley, - - 2014
In the last decade, the introduction of the serum-free light-chain (sFLC) assay has been an important advance in the diagnosis and management of plasma cell dyscrasias, particularly monoclonal light-chain diseases. The immunoassay was developed to detect free light chains in serum by using anti-FLC antibodies which specifically recognised epitopes on ...
Hefferman Gerald M GM 1Neuromuscular Rehabilitation Engineering Laboratory, Department of Electrical, Computer, and Biomedical Engineering, University of Rhode Island, Kingston, - - 2014
Background and aim:In recent years, there has been an increased interest in recording high-quality electromyographic signals from within the sockets of lower-limb amputees. However, successful recording presents major challenges to both researchers and clinicians. This article details and compares four prototypical integrated socket-sensor designs used to record electromyographic signals from ...
Lowrey Catherine R CR 1Queen's - - 2014
Skin sensory input from the foot soles is coupled with vestibular input to facilitate body orientation in a gravitational environment. Anecdotal observations suggest that foot sole skin becomes hypersensitive following space flight. The veritable level of skin sensitivity and its impact on postural disequilibrium observed post space flight have not ...
Marta S N SN Dentistry School, Graduate Studies, Sacred Hearth University, Bauru, - - 2014
The aim of this study is to evaluate the light-touch sensation of the oral mucosa in leprosy patients. A cross-sectional study included 228 adults, 133 being leprosy patients and 95 normal controls. To assess light-touch sensation, the five-filament standard Semmes-Weinstein kit in eight regions of the oral mucosa was used. ...
Kim Hyo-Jung HJ Biomedical Research Institute, Seoul National University Bundang Hospital, Seongnam, - - 2014
Rebound nystagmus is a transient nystagmus that occurs on resuming the straight-ahead position after prolonged eccentric gaze. Even though rebound nystagmus is commonly associated with gaze-evoked nystagmus (GEN), development of rebound nystagmus in a different plane of gaze has not been described. We report a patient with episodic ataxia type ...
Jin Guorui G Department of Mechanical Engineering, National University of Singapore, 2 Engineering Drive 3, Singapore, 117576; Center for Nanofibers and Nanotechnology, E3-05-14, Nanoscience and Nanotechnology Initiative, Faculty of Engineering, National University of Singapore, 2 Engineering Drive 3, Singapore, - - 2014
Tissue engineered skin grafts that mimic the native extracellular matrix (ECM) of skin has gained huge popularity among clinicians since they increase the survival rate of the patients. Phototherapy shows promising results with respect to acute and chronic pain relief, treatment of inflammatory conditions, and promotion of wound healing. Here, ...
Lyyra Pessi P Department of Psychology, University of Jyväskylä, Jyväskylä, Finland ; Human Information Processing Laboratory, School of Social Sciences and Humanities, University of Tampere, Tampere, - - 2014
Change blindness refers to the inability to detect visual changes if introduced together with an eye-movement, blink, flash of light, or with distracting stimuli. Evidence of implicit detection of changed visual features during change blindness has been reported in a number of studies using both behavioral and neurophysiological measurements. However, ...
Giannoni Alberto A International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College, London, United Kingdom ; Department of Cardiovascular Medicine, Fondazione Toscana G. Monasterio, Pisa, - - 2014
Clinicians are sometimes advised to make decisions using thresholds in measured variables, derived from prognostic studies. We studied why there are conflicting apparently-optimal prognostic thresholds, for example in exercise peak oxygen uptake (pVO2), ejection fraction (EF), and Brain Natriuretic Peptide (BNP) in heart failure (HF). Studies testing pVO2, EF or ...
Yang Shifeng S Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, P.R. - - 2014
To evaluate the feasibility of dose-modulated retrospective ECG-gated thoracoabdominal aorta CT angiography (CTA) assessing abdominal aortic intimal flap motion and investigate the motion characteristics of intimal flap in acute aortic dissection (AAD). 49 patients who had thoracoabdominal aorta retrospective ECG-gated CTA scan were enrolled. 20 datasets were reconstructed in 5% ...
Kraj Maria M Institute of Hematology and Transfusion Medicine, Warsaw, - - 2014
Immunofixation (IFE) is a standard method for detecting monoclonal immunoglobulins and characterizing its isotype. Recently clonality can also be determined by using immunoglobulin (Ig) heavy chain/light chain immunoassays - HLC, HevyliteTM. HLC separately measures in pairs light chain types of each intact Ig class generating ratios of monoclonal Ig/uninvolved polyclonal ...
Coste Christine Azevedo CA INRIA-LIRMM, Montpellier 34095, France. - - 2014
Freezing of gait (FOG) is a common symptom in Parkinsonism, which affects the gait pattern and is associated to a fall risk. Automatized FOG episode detection would allow systematic assessment of patient state and objective evaluation of the clinical effects of treatments. Techniques have been proposed in the literature to ...
Wunsch Alexander - - 2013
Abstract Objective: The purpose of this study was to investigate the safety and efficacy of two novel light sources for large area and full body application, providing polychromatic, non-thermal photobiomodulation (PBM) for improving skin feeling and appearance. Background data: For non-thermal photorejuvenation, laser and LED light sources have been demonstrated ...
Graziani Maria Stella - - 2013
The serum free light chain (FLC) assay is an important tool in the management of patients with monoclonal gammopathies. MEDLINE®, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews from January 2000 through July 2013, were used as data sources. The available evidence is rather ...
Jafari Zahra - - 2013
Human modalities play a vital role in the way the brain produces mental representations of the world around us. Although congenital blindness limits the understanding of the environment in some aspects, blind individuals may have other superior capabilities from long-term experience and neural plasticity. This study investigated the effects of ...
Bhorade Anjali M - - 2013
IMPORTANCE Patients often report greater visual difficulties at home than expected from vision testing in the clinic. Such discordance may be owing to worse vision in the home than measured in clinic. OBJECTIVE To compare vision measured between the clinic and home and evaluate factors, including lighting, associated with these ...
Jee T T Department of Mechanical Engineering, University of California, Berkeley, CA 94720, - - 2013
Time-dependent deformation of porcine skin was studied in vitro using specialized microprobe instruments. The deformation behavior of stratum corneum, dermis, and whole skin is examined in the context of results of creep strain, elastic stiffness, and viscoelastic constants obtained in terms of the hold time, loading/unloading rate, and maximum indentation ...
Korenbrot Juan I - - 2013
The ligand sensitivity of cGMP-gated (CNG) ion channels in cone photoreceptors is modulated by CNG-modulin, a Ca(2+)-binding protein. We investigated the functional role of CNG-modulin in phototransduction in vivo in morpholino-mediated gene knockdown zebrafish. Through comparative genomic analysis, we identified the orthologue gene of CNG-modulin in zebrafish, eml1, an ancient ...
Zhang Pengpeng - - 2013
To develop an optimization algorithm for volumetric modulated arc therapy which incorporates an electromagnetic tracking (EMT) guided gating strategy and is robust to residual intra-fractional motion uncertainties. In a computer simulation, intra-fractional motion traces from prior treatments with EMT were converted to a probability distribution function (PDF), truncated using a ...
de Boer-Schellekens Liselotte - - 2013
Here, we examined sensitivity of visual, auditory, and audiovisual temporal order in five age-groups (20 to 70 years old). We also measured multisensory integration (MSI) using a phenomenon known as "temporal ventriloquism," in which click sounds improve sensitivity of visual temporal order. Results showed that sensitivity of visual, auditory, and audiovisual ...
Baldwin Margaret - - 2013
This study examined the ability of click auditory brainstem response (ABR) undertaken below the age of 6 months (from expected date of delivery) to differentiate between conductive and sensorineural hearing loss (SNHL), using the latency of wave V measured 20 dB above threshold. Subjects were recruited if they had an ...
Ye Yun - - 2013
The study aimed to evaluate the levels of serum free kappa (κ) and lambda (λ) light chains in patients with rheumatoid arthritis (RA) as well as exploring the association between serum free κ and λ light chains and activity of RA. For this purpose, healthy individuals and patients with active RA ...
Alexis A F - - 2013
Ethnic skin or 'skin of colour', which is characterized by increased epidermal melanin, labile melanocytes and reactive fibroblast responses, poses special challenges for the use of laser and light-based therapies. These therapies are associated with a greater risk of dyspigmentation and scarring in ethnic skin and therefore require careful selection ...
Mamalis A D - - 2013
Keloids are an overgrowth of fibrotic tissue outside the original boundaries of an injury and occur secondary to defective wound healing. Keloids often have a functional, aesthetic, or psychosocial impact on patients as highlighted by quality-of-life studies. Our goal is to provide clinicians and scientists an overview of the data ...
Zopf Lydia M - - 2013
The spectral sensitivity of adult male Cupiennius salei Keys, a nocturnal hunting spider, was studied in a behavioural test. As known from earlier behavioural tests, C. salei walks towards a black target presented in front of a white background. In this study a black target (size 42 x 70 cm) ...
Kelemen Oguz - - 2013
Schizophrenia is characterized by anomalous perceptual experiences (e.g., sensory irritation, inundation, and flooding) and specific alterations in visual perception. We aimed to investigate the effects of short-term antipsychotic medication on these perceptual alterations. We assessed 28 drug-naïve first episode patients with schizophrenia and 20 matched healthy controls at baseline and ...
Tronstad Christian - - 2013
The shapes of skin conductance (SC) and skin potential (SP) responses are often similar, but can also be very different due to an unexplained cause. Using a new method to measure SC and SP simultaneously at the same electrode, this difference was investigated in a new way by comparing their ...
Lin Yuting - - 2013
The objective of this work is to characterize and quantify the impact of respiratory-induced prostate motion. Real-time intrafraction motion is observed with the Calypso 4-dimensional nonradioactive electromagnetic tracking system (Calypso Medical Technologies, Inc. Seattle, Washington). We report the results from a total of 1024 fractions from 31 prostate cancer patients. ...
Muhammed Louwai L Green Templeton College, Oxford, - - 2013
It has been suggested that undiagnosed epilepsy profoundly influenced the lives of several key figures in history. Historical sources recounting strange voices and visions may in fact have been describing manifestations of epileptic seizures rather than more supernatural phenomena. Well-documented accounts of such experiences exist for three individuals in particular: ...
Bronstein Adolfo M - - 2013
The normal vestibular system may be adversely affected by environmental challenges which have characteristics that are unfamiliar or ambiguous in the patterns of sensory stimulation they provide. A disordered vestibular system lends susceptibility even to quotidian environmental experiences as the sufferer becomes dependent on potentially misleading, nonvestibular sensory stimuli. In ...
Emmanouilidou Dimitra - - 2013
Lung sound auscultation in non-ideal or busy clinical settings is challenged by contaminations of environmental noise. Digital pulmonary measurements are inevitably degraded, impeding the physician's work or any further processing of the acquired signals. The task is even harder when the patient population includes young children. Agitation and/or crying are ...
Feng Chunliang - - 2013
By comparing faces with Chinese characters, the category-sensitive and orientation-sensitive N170 adaptation effects were examined when the stimuli were adapted by category (within vs. between) and orientation (same vs. different). The category-sensitive N170 adaptation was present for both faces and characters, supporting the assertion that the perception of faces and ...
Chang Ernest W - - 2013
Efficient transfer of sound by the middle ear ossicles is essential for hearing. Various pathologies can impede the transmission of sound and thereby cause conductive hearing loss. Differential diagnosis of ossicular disorders can be challenging since the ossicles are normally hidden behind the tympanic membrane (TM). Here we describe the ...
Starrfelt Randi - - 2013
Pure alexia is a selective deficit in reading, following lesions to the posterior left hemisphere. Writing and other language functions remain intact in these patients. Whether pure alexia is caused by a primary problem in visual perception is highly debated. A recent hypothesis suggests that a low level deficit - ...
Messias Katharina - - 2013
PURPOSE: The purpose of this study is to describe the relationships between full-field stimulus threshold (FST), electroretinography (ERG), and visual field (VF) outcomes in retinitis pigmentosa (RP). METHODS: Data from 47 patients with RP (n = 94 eyes) were evaluated. Patients were submitted to comprehensive ophthalmological examination including measurement of best-corrected visual ...
Radford C A CA Leigh Marine Laboratory, University of Auckland, Warkworth 0941, New Zealand. - - 2013
The New Zealand bigeye, Pempheris adspersa, is a nocturnal planktivore and has recently been found to be an active sound producer. The rostral end of the swim bladder lies adjacent to Baudelot's ligament which spans between the bulla and the cleithrum bone of the pectoral girdle. The aim of this ...
Maus Gerrit W - - 2013
Adaptation is one of the longest-studied phenomena in perception and neuroscience. Adaptation generally results in negative perceptual aftereffects: after prolonged exposure to a specific feature, perception of a neutral stimulus is biased in the opposite direction [1,2]. A recent paper in Current Biology[3] challenged this view by proposing that, additionally, ...
Kulik Gerit - - 2013
PURPOSE: Neurophysiological monitoring aims to improve the safety of pedicle screw placement, but few quantitative studies assess specificity and sensitivity. In this study, screw placement within the pedicle is measured (post-op CT scan, horizontal and vertical distance from the screw edge to the surface of the pedicle) and correlated with ...
Cha Yoon-Hee - - 2013
BACKGROUND: Chronic rocking dizziness, often described as the feeling of being on a boat, is classically triggered by prolonged exposure to passive motion. Patients with this motion-triggered sensation of rocking, which is also known as MAL DE DEBARQUEMENT SYNDROME , often develop new onset headaches along with the dizziness. Chronic ...
McNamara Joseph E - - 2013
Purpose: Real-time tracking of respiratory target motion during radiation therapy is technically challenging, owing to rapid and possibly irregular breathing variations. The authors report on a method to predict and correct respiration-averaged drift in target position by means of couch adjustments on an accelerator equipped with such capability.Methods: Dose delivery ...
Nordin Steven - - 2013
Previous research has indicated that sensory sensitivity/intolerance to a specific modality may be part of a more general environmental hypersensitivity, and possibly mediated by stress. This study investigated the relationship between noise sensitivity, perceived stress, and odor sensitivity in a group of men. A quasi-experimental design was used. One-hundred and ...
Barboni Mirella Telles Salgueiro - - 2013
The study investigated possible asymmetric dysfunction of the ON and OFF visual mechanisms in DMD (Duchenne muscular dystrophy) patients associated with specific genetic alterations. Methods: nineteen DMD patients and 7 heterozygous dmd carriers were tested, as well as 19 age-matched controls.Full-field ergs were recorded using mesopic (1 cd/m(2)) and photopic ...
Yang S-W - - 2013
This study aimed to investigate the clinical efficacy of using broadband white light (BWL) to observe morphologic appearance, narrow-band imaging (NBI) to observe intraepithelial microvasculature, and both BWL and NBI for the detection of high-grade dysplasia and carcinoma in oral leukoplakia. Among 317 patients (274 males and 43 females; aged ...
Al-Khassaweneh Mahmood - - 2013
Abstract Asthma is not very easy to be correctly diagnosed by physicians where asthma is considered a common chronic inflammatory disease. Distinguishing of cough sound can be used to diagnose asthma. The use of signal processing techniques of cough sound for detecting asthma will be addressed in this paper to ...
Lima Fabiana Benites Vaz de - - 2013
Visual processing deficits have been reported for patients with schizophrenia. Previous studies demonstrated differences in early-stage processing of schizophrenics, although the nature, extent, and localization of the disturbance are unknown. The magnocellular and parvocellular visual pathways are associated with transient and sustained channels, but their respective contributions to schizophrenia-related visual ...
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