Search Results
Results 351 - 400 of 862
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Abbas Ghulam - - 2009
INTRODUCTION: Cholangiocarcinoma (CCA) is an aggressive and nearly always fatal tumor of the biliary tract. PURPOSE: This review explores risk factors, epidemiology, current diagnostic approaches, and treatment of CCA arising in patients with primary sclerosing cholangitis (PSC). METHODS: We review latest recommendations about screening strategies to enable the early detection ...
Luesley David - - 2009
BACKGROUND: Colposcopy is a secondary screening test used after a cytological specimen is reported as abnormal. A negative or normal colposcopy is not an infrequent outcome, and clinicians need to be aware of the clinical value of a normal and satisfactory colposcopic assessment.To address this problem, the underlying causes need ...
Shousha S - - 2009
AIMS: To validate the use of the silver-enhanced in situ hybridization (SISH) technique in assessing HER2 status of breast carcinoma in excision biopsy specimens, and to assess its reliability in determining HER2 status in core biopsy specimens. METHODS AND RESULTS: Routinely processed paraffin sections of 65 excised breast carcinomas and ...
Hrisos Susan - - 2009
ABSTRACT: BACKGROUND: Accurate measures of health professionals' clinical practice are critically important to guide health policy decisions, as well as for professional self-evaluation and for research-based investigation of clinical practice and process of care. It is often not feasible or ethical to measure behaviour through direct observation, and rigorous behavioural ...
Renganathan Arasee - - 2009
AIMS: To review the quality of urodynamic traces collected as part of a multi-center Phase II drug trial of a medication for overactive bladder (OAB), in order to assess adherence to the Good Urodynamic Practice (GUP) guidelines. To assess inter-rater reliability (IRR) for the numerical cystometrogram variables, and for the ...
Leroy Nicolas - - 2009
The European project PSIP (Patient Safety through Intelligent Procedures in Medication) aims at semi-automatically identifying and preventing ADE. Automatically detected Adverse Drug Events have to be reviewed and validated by human experts. Existing methods usually have the experts review the cases and document their rating in a structured form. One ...
Toerien Merran M Department of Sociology, The University of York, Heslington, York, YO10 4PS, UK. - - 2009
Poor recruitment and retention of participants in randomised controlled trials (RCTs) is problematic but common. Clear and detailed reporting of participant flow is essential to assess the generalisability and comparability of RCTs. Despite improved reporting since the implementation of the CONSORT statement, important problems remain. This paper aims: (i) to ...
Parida Pradipta Kumar - - 2008
Rosai Dorfman disease or sinus histiocytosis is a rare, idiopathic, benign and self-limiting histiocytic proliferative disorder, usually seen in younger patients. It most commonly involves the cervical lymph nodes, with a predominant infiltration of sinusoidal histiocytes and classically presents with massive cervical lymhadenopathy. Extranodal disease occurs in about 43% of ...
Fidler Jeff L - - 2008
OBJECTIVE: Two-thirds of the US population is overweight or obese. Sedentary lifestyles and occupations are one factor in the development of obesity. Methods to help reduce sedentary work environments may help reduce obesity. The purpose of this study was to determine the feasibility of using a walking workstation during computed ...
Kieval J Z - - 2009
To evaluate the role and efficacy of portable X-ray in reliably identifying retained suture needles in ophthalmologic surgical cases. Ophthalmologic 10-0 nylon suture needles were placed into 10 of 20 porcine eyes positioned within the orbit of a human skull. Portable, plain film radiographs were taken of all eyes with ...
Murphy Michael E - - 2008
BACKGROUND: Errors can occur in the interpretation of Mohs histopathology sections. Errors in histology interpretation can lead to incomplete removal of cancer and cancer persistence or the unnecessary removal of uninvolved tissue. Extensive proctored training is necessary to reduce these errors to an absolute minimum level. OBJECTIVE: To analyze and ...
Mann Rachel - - 2009
BACKGROUND: There has been an increase in the number of systematic reviews of diagnostic tests, which has resulted in the introduction of two checklists: statement for reporting of diagnostic accuracy (STARD) and quality assessment of diagnostic accuracy studies (QUADAS). OBJECTIVE: To examine the validity and usefulness of QUADAS when applied ...
Chen Wen-Xiong - - 2008
OBJECTIVE: The objective of this study was to observe for efficacy, safety, and compliance of electroacupuncture for autism spectrum disorder (ASD). METHODS: Two (2) children with ASD received electroacupuncture for 24 sessions over 8 weeks and were assessed pre- and postacupuncture. We defined a positive or negative change as an ...
Gleeson Helena K - - 2008
AIM: To assess the benefits and practicalities of setting up a newborn screening (NBS) program in Australia for congenital adrenal hyperplasia (CAH) through a 2 year pilot screening in ACT/NSW and comparing with case surveillance in other states. METHODS: The pilot newborn screening occurred between 1/10/95 and 30/9/97 in NSW/ACT. ...
Kohl Katrin S - - 2008
We evaluated the applicability, reliability, sensitivity, and specificity of six standardized case definitions for adverse events following immunization (AEFI) (for fever, generalized convulsive seizure, hypotonic-hyporesponsive episode, intussusception, nodule, and persistent crying) developed by the Brighton Collaboration using the U.S. Vaccine Adverse Event Reporting System (VAERS). The evaluation included: (a) the ...
Kennie Natalie - - 2008
OBJECTIVE: To develop and test the reliability of a case-leveling framework for assigning level of difficulty of the pharmacist's task for initial medication assessments conducted by pharmacists integrated into family physician offices. DESIGN: Descriptive study. SETTING: Seven family practice sites in Ontario from June 2004 to July 2006. PATIENTS: Patients ...
Mishra Anupam - - 2008
We present a very unique case of a premaxillary chondrosarcoma arising in a relatively 'younger' female with apparently much 'better' disease free 7-year survival. The literature has been reviewed and a meaningful discussion regarding diagnosis and treatment is highlighted.
Accetta Nancy A - - 2008
Routine laboratory reporting of estimated glomerular filtration rate (eGFR) may help clinicians detect kidney disease. The current national prevalence of eGFR reporting in clinical laboratories is unknown; thus, the extent of the situation of laboratories not routinely reporting eGFR with serum creatinine results is not quantified. Observational analysis. National Kidney ...
Trudel Judith L - - 2008
OBJECTIVE: The purpose of this study was to determine the reliability and validity of the scores from "key feature" cases in the self-assessment of colon and rectal surgeons. BACKGROUND: Key feature (KF) cases specifically focus on the assessment of the unique challenges, critical decisions, and difficult aspects of the identification ...
Keen Andrew J A - - 2008
BACKGROUND: Postgraduate courses on cognitive-behavioural therapy (CBT) assess various competencies using essays, case studies and audiotapes or videotapes of clinical work. AIMS: To evaluate how reliably a well-established postgraduate course assesses CBT competencies. METHOD: Data were collected on two cohorts of trainees (n=52). Two examiners marked trainees on: (a) two ...
Patel Anand K - - 2008
PURPOSE OF REVIEW: This article reviews the literature from the last 12 months in the context of our existing knowledge base and reviews the contentious issue of the role of preoperative urodynamics for stress urinary incontinence, with particular reference to the choice of urodynamic investigations for diagnostic differentiation between intrinsic ...
Depuydt Christophe E - - 2009
The objective of this prospective study was to compare the number of CIN2+cases detected in negative cytology by different quality control (QC) methods. Full rescreening, high-risk (HR) human papillomavirus (HPV)-targeted reviewing and HR HPV detection were compared. Randomly selected negative cytology detected by BD FocalPoint (NFR), by guided screening of ...
Jha A - - 2008
Filariasis is a common disabling parasitic disease in this region and cytological diagnosis is often not required. Cytology has important role in diagnosis of sub-clinical filariasis. Most cases of cytologically diagnosed filariasis are clinically unanticipated. Microfilaria, ova and fragments of adult worm of Wuchereria bancrofti, in exfoliative as well as ...
Koperek O - - 2008
AIMS: To evaluate the reliability of desmoplasia as a reproducible morphological parameter indicating the metastatic potential of medullary thyroid carcinoma (MTC). METHODS AND RESULTS: One hundred and twenty cases of MTC of the Medical University of Vienna, Austria and 76 cases from the School of Medicine of Marseille, France were ...
Cao Hui - - 2008
Inter-case similarity metrics can potentially help find similar cases from a case base for evidence-based practice. While several methods to measure similarity between cases have been proposed, developing an effective means for measuring patient case similarity remains a challenging problem. We were interested in examining how abstracting could potentially assist ...
D'Hue Zandra - - 2008
BACKGROUND: Onychomycosis is a common cause of deformed nails. Periodic acid-Schiff (PAS) stains are more sensitive than fungal cultures for diagnosing onychomycosis. We performed a retrospective study comparing the use of PAS and Gomori methenamine silver (GMS) stains for histopathologic diagnosis of onychomycosis. METHODS: GMS stains were performed on 20 ...
Weller J M - - 2008
A reliable assessment of clinical performance requires multiple cases, as performance varies between cases depending on previous experiences and knowledge of the case. However, behavioural attributes, including communication and teamwork, may be expected to be less dependent on specific case knowledge and thus be more stable across cases. This has ...
Barton James C - - 2008
There are few descriptions of young adults with self-reported hemochromatosis or iron overload (H/IO). We analyzed initial screening data in 7,343 HEmochromatosis and IRon Overload Screening (HEIRS) Study participants ages 25-29 years, including race/ethnicity and health information; transferrin saturation (TS) and ferritin (SF) measurements; and HFE C282Y and H63D genotypes. ...
Kaldjian Lauris C - - 2008
BACKGROUND: Collecting data on medical errors is essential for improving patient safety, but factors affecting error reporting by physicians are poorly understood. METHODS: Survey of faculty and resident physicians in the midwest, mid-Atlantic, and northeast regions of the United States to investigate reporting of actual errors, likelihood of reporting hypothetical ...
Lammers T - - 2008
For thrombophilia should be screened, if a first thromboembolic event has occurred at the age of less than 45 years, if family history indicates thrombophilia, or in the case of a special clinical condition. To get valid diagnostic results a few pecularities concerning the physiology of coagulation and laboratory medicine ...
Wójcik Janusz - - 2008
Thoracic splenosis of the left lung and upper abdominal area was described. Left minithoracotomy was performed due to unclear results from a fine needle biopsy and following the suggestion to obtain a tissue sample. Clinical findings were similar to neoplasmatic disease; intraoperative extension of the disease was larger than CT ...
Policarpio-Nicolas Maria Luisa C - - 2008
Pulmonary cytology has progressed over the past decades because of advancement in imaging studies and increased confidence of pathologists in cytomorphologic diagnosis. It has an overall sensitivity and specificity ranging from approximately 60 to 96%. However, even with the most conscientious laboratories, false-positive diagnoses of malignancy do occur in respiratory ...
Friedlin Jeff - - 2008
We examined whether using a natural language processing (NLP) system results in improved accuracy and completeness of automated electronic laboratory reporting (ELR) of notifiable conditions. We used data from a community-wide health information exchange that has automated ELR functionality. We focused on methicillin-resistant Staphylococcus Aureus (MRSA), a reportable infection found ...
Huettig M - - 2008
PURPOSE: Sonographic reports are examiner-dependent and may not always be reliable. We investigated concordance between documented findings and diagnostic conclusions--not the objective correctness of both--with the help of a knowledge-based documentation system. MATERIALS AND METHODS: The knowledge-based documentation system SonoConsult (SC) is routinely used in the ultrasound unit of a ...
Maeck Lienhard - - 2008
AIM: To investigate whether primary-care physicians' competency regarding dementia diagnostics improved from 1993 to 2001. METHODS: In a representative follow-up survey 122 out of 170 (71.8%) family physicians (FPs) were randomly assigned to 2 written case samples presenting patients with slight memory impairment (case 1a: female vs. case 1b: male) ...
Passamonti Basilio - - 2007
OBJECTIVE: To evaluate the FocalPoint Location-Guided Screening (FPGS) performance in computer-assisted primary screening of Papanicolaou-stained cervicovaginal smears. STUDY DESIGN: A total of 37,306 routine consecutive conventional Pap slides were prospectively processed on the FPGS. Each slid designated by the instrument as Review was reported according to results obtained using a ...
Li Xinxia - - 2008
To assess the feasibility, including diagnostic accuracy and time cost, of a real-time telepathology system with pathologic slides, 600 cases covering a wide spectrum of lesions from 16 organ systems were tested. The "correct" diagnosis (gold standard) was established as a consensus by 2 experienced pathologists. The cases were first ...
Middleton E M - - 2008
PURPOSE: The association between psychological difficulties and accommodative insufficiency in children and young adults has been previously reported. The authors give their experiences with such cases and address the research and service developments required to deal with these problems. METHODS: When no other organic pathology was found in full ophthalmological ...
Charter Richard A - - 2007
KR-21 provides a lower limit for the computed value of KR-20. KR-20 is equivalent to coefficient alpha when a test is composed of dichotomous items scored 0 or 1. Therefore, KR-21 coefficients, computed from simple summary statistics, can be used in cases in which journal authors do not provide the ...
Carreon Joseph D - - 2007
We wished to compare the relative reproducibility and validity of cervical intraepithelial neoplasia (CIN) 2 and CIN3 diagnoses. In a population-based cohort study (1993-2001) of human papillomavirus (HPV) and cervical neoplasia in Costa Rica, we compared community pathologists' diagnoses with those of the 2 independent reviewers from the United States ...
Wood Benjamin - - 2007
AIMS: To compare immunohistochemical staining for oestrogen receptor, progesterone receptor and HER-2 between core biopsy and matched subsequent excisional specimens. METHODS: One hundred consecutive core biopsy cases and subsequent excisional specimens were retrieved and immunohistochemical staining performed. Proportion and intensity of staining for hormone receptors and HercepTest score were recorded ...
Perry Linda - - 2007
Excavations at Guilá Naquitz and Silvia's Cave, two dry rockshelters near Mitla, Oaxaca, Mexico, yielded the remains of 122 chili peppers dating to the period A.D. 600-1521. The chilies can be assigned to at least 10 cultivars, all belonging to the species Capsicum annuum or Capsicum frutescens. The specimens are ...
Lilford Richard - - 2007
OBJECTIVE: The quality of clinical care is often assessed by retrospective examination of case-notes (charts, medical records). Our objective was to determine the inter-rater reliability of case-note audit. METHODS: We conducted a systematic review of the inter-rater reliability of case-note audit. Analysis was restricted to 26 papers reporting comparisons of ...
Geijer M - - 2007
BACKGROUND: Computed tomography (CT) for evaluation of sacroiliitis has a higher diagnostic accuracy than radiography. There is a high degree of interobserver variation in evaluating sacroiliitis on radiographs. PURPOSE: To evaluate interobserver variation in CT of the sacroiliac joints for evaluation of sacroiliitis in a large number of patients. MATERIAL ...
Johnson Zoë K - - 2007
OBJECTIVE: To evaluate the quality of reporting of diagnostic accuracy studies using optical coherence tomography (OCT) in glaucoma. DESIGN: Descriptive series of published studies. PARTICIPANTS: Published studies reporting a measure of the diagnostic accuracy of OCT for glaucoma. METHODS: Review of English language papers reporting measures of diagnostic accuracy of ...
Forster Alan J - - 2007
OBJECTIVES: Adverse events (AEs) are poor patient outcomes, resulting from medical care. We performed this study to quantify the misclassification rate obtained using current AE detection methods and to evaluate the effect of combining physician AE ratings. STUDY DESIGN AND SETTING: Three physicians independently rated poor patient outcomes. We used ...
Straub Jürg Oliver - - 2007
An environmental risk assessment (ERA) was made for the common nonsteroidal anti-inflammatory drug naproxen. The ERA was performed according to deterministic and probabilistic methods, based on different predicted environmental concentrations (PECs) and measured environmental concentrations (MECs) on the exposure side as well as on published and newly elaborated acute ecotoxicity ...
Smith Albert F - - 2007
To compare two approaches to analysing energy- and nutrient-converted data from dietary validation (and relative validation) studies - conventional analyses, in which the accuracy of reported items is not ascertained, and reporting-error-sensitive analyses, in which reported items are classified as matches (items actually eaten) or intrusions (items not actually eaten), ...
Adler Mark D - - 2007
OBJECTIVE: Pediatric residency programs need objective methods of trainee assessment. Patient simulation can contribute to objective evaluation of acute care event management skills. We describe the development and validation of 4 simulation case scenarios for pediatric resident evaluation. METHODS: We created 4 pediatric simulation cases: apnea, asthma, supraventricular tachycardia, and ...
Sandhaus Linda M - - 2007
CONTEXT: Despite the widespread practice of pathologist review of blood and body fluid smears, little is known about its impact on improving patient care. OBJECTIVE: To assess the clinical usefulness of pathologist review of blood and body fluid smears. DESIGN: Survey study. Pathology residents contacted the ordering physician after pathologist ...
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