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Bakr Farrah F St John's Institute of Dermatology, St Thomas' Hospital, London. Electronic address: - - 2014
Intralymphatic histiocytosis (IH) is a rare condition often associated with systemic disease. A benign condition, clinical presentations can vary greatly and its cause is largely unknown. Histologically, there are macrophages within distended lymphatic vessels, although this can be an incidental finding or the primary abnormality. We present a series of 7 ...
Joshi Heman M N HM Liverpool Heart and Chest Hospital, Liverpool, United Kingdom. Electronic address: - - 2014
Giant pulmonary hamartomas are rare. We describe a case of a 59-year-old female patient with a giant chondroid hamartoma in the lower lobe of the right lung presenting with acute right heart failure. To the best of our knowledge such a unique presentation has not been previously described in the ...
Ghaemi Nosrat N Department of Pediatrics, School of Medicine, Mashhad University of Medical sciences, Mashhad, - - 2014
Thyroid gland is well known to resist infections by rich blood supply and lymphatic drainage, high glandular content of iodine which can be bactericidal and separation of the gland from other structures of neck. Primary thyroid abscess resulting from acute suppurative thyroiditis (AST) is an unusual type of head and ...
Zhou Xiao-Nong XN National Institute of psitic Diseases, Shanghai, China CDC. - - 2014
The editors of Infectious Diseases of Poverty would like to thank all our reviewers who have contributed to the journal in Volume 2 (2013).
Amadei Enrico Maria EM Department of Otorhinolaryngology, Head and Neck Surgery, S. Orsola-Malpighi University Hospital, Via Pietro Albertoni 15, 40138 Bologna, - - 2014
Several are the causes of cervical masses and among them a spontaneous hemorrhage presents a rare and life-threatening condition. Sometimes hemorrhage develops from a previous silent neck lesion as in the case of an anaplastic thyroid carcinoma associated with bleeding. We present two cases: a 70-year-old woman suffering from enlarging ...
Schwartz Emily N EN Family Medicine Physician at the Los Angeles Medical Center in CA. - - 2014
One of the challenges in the treatment of plantar fasciitis is that there are very few high-quality studies comparing different treatment modalities to guide evidence-based management. Current literature suggests a change to the way that plantar fasciitis is managed. This article reviews the most current literature on plantar fasciitis and ...
Warpe Bhushan M BM Department of Pathology, Indira Gandhi Government Medical College, Nagpur, - - 2014
Rosai-Dorfman disease (RDD) is also known as Sinus Histiocytosis with Massive Lymphadenopathy (SHML). It is a rare, benign, self-limiting disease of phagocytic histiocytes affecting a young age group presenting with massive painless cervical lymphadenopathy. RDD has nodal and also extra-nodal involvement with episodes of exacerbation and remissions, whose aetiology remains ...
Chadha Nisha N Department of Ophthalmology, The George Washington University, Washington, DC, - - 2014
Cyclodialysis cleft is a rare clinical finding and therefore, reports on surgical repair techniques in the literature are limited. Additionally, hypotony can make repair technically challenging. We share a novel, simple surgical approach to management of a case of chronic traumatic cyclodialysis cleft with a successful outcome.
Mookkappan Sudhagar S Department of General Medicine, Pondicherry Institute of Medical - - 2014
Scrub typhus appears throughout the Asia-Pacific rim. This disease is known for its diverse clinical manifestations and complications. There is no literature on the association of scrub typhus with adrenal insufficiency. Relative bradycardia has been reported in scrub typhus during the febrile phase but not during convalescence. We report the ...
Papastefanou V P VP Ocular Oncology Service, St Bartholomew's and Moorfields Eye Hospital, London EC1A 7BE, - - 2014
Choroidal metastases from follicular thyroid carcinoma are uncommon and usually present as an amelanotic lesion against a background of known systemic disease. We present the case of a 56-year-old woman with a thyroid metastatic focus with unusual clinical presentation, systemic involvement, and early response to systemic treatment. A review of ...
Alfadda Assim A AA Department of Medicine, College of Medicine, King Saud University, P.O. Box 2925 (38), Riyadh 11461, Saudi - - 2014
Few studies have been reported from the Kingdom of Saudi Arabia (SA) to describe the clinical presentation and long term outcomes of subacute thyroiditis (SAT). Our aim was to review the demographic, anthropometric, clinical presentation, laboratory results, treatment, and disease outcome in Riyadh region and to compare those with results ...
Tsitskaris Konstantinos K University College Hospital, London, - - 2014
We report the case of an osteoid osteoma in the dorsal talar neck of a healthy long-distance runner, masquerading as anterior ankle impingement syndrome. We discuss the diagnosis and successful treatment using percutaneous CT-guided laser photocoagulation. A concise review of the principles of the management of osteoid osteomas is also ...
Akinbami Akinsegun A Department of Haematology and Blood Transfusion, College of Medicine, Lagos State University, PMB 21266, Ikeja, Lagos, Lagos State, - - 2014
The Kikuchi-Fujimoto is a rare, self-limiting disease, which is characterized by regional lymphadenopathy. It occurs worldwide with a higher prevalence among Asians and women below the age of forty years. We present 41-year-old Nigerian woman who was investigated extensively for unilateral left cervical lymphadenopathy. She was eventually diagnosed as having ...
Bird Nicholas Te NT General Surgery, University Hospital Aintree, Lower Lane, Liverpool L97AL, - - 2014
Lemierre's disease is characterized by sepsis, often with an oropharyngeal source, secondary septic emboli and internal jugular vein thrombosis (Lancet 1:701-3, 1936. Clin Microbiol Rev 20(4):622-59, 2007). Septic emboli affecting many bodily sites have been reported, including the lungs, joints, bones, and brain. The case report describes an unusual case ...
Rahimi Saeed S Dental and Periodontal Research Center, Dental School, Tabriz University of Medical Sciences, Tabriz, - - 2014
Microorganisms play a major role in initiation and perpetuation of pulpal and periapical diseases. Therefore, elimination of the microorganisms present in the root canal system is the fundamental objective of endodontic treatment. The use of mechanical debridement, chemical irrigation or other antimicrobial protocols and intra-canal medicaments are critical to attain ...
J Ashok Raja AR Department of Neonatology, ICH & RC, Madurai, Tamil Nadu, - - 2014
Sternal cleft is a rare anomaly comprising 0.5% of chest wall malformations. We present a case of a neonate with a 'V'-shaped upper partial sternal cleft at birth. A hyperpigmented cutaneous nevi was present over the cleft. Primary approximation and closure of the defect was performed at 1 week of life. ...
Najib Jaafar J Service de Neurochirurgie, CHU Beaujon, Paris, - - 2014
Forestier's disease, also known as diffuse idiopathic skeletal hyperostosis (DISH), is a pathology of vertebral bodies characterised by exuberant osteophytis formation. Forestier's disease is usually managed conservatively. Surgical resection of the osteophytes is reported to be an effective treatment for severe cases and/ or cases with airway obstruction. We report ...
Ciorba Andrea A ENT and Audiology Department, University Hospital of Ferrara, Via Aldo Moro, Cona, 8 44124 Ferrara, - - 2014
Background. Carcinosarcoma is an extremely rare malignant neoplasm, with both a malignant epithelial and mesenchymal component, that rarely affects the larynx. Aim. Aim of this paper is to describe the case of a patient affected by a larynx carcinosarcoma treated by endoscopic horizontal partial laryngectomy with CO(2) laser and particularly ...
McDonnell O O NIISWA, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Perth, WA 6009, - - 2014
Localised nasopharyngeal Castleman disease has rarely been reported. We present a case involving a 23-year-old female, describe the clinical, imaging, and histopathologic features of this challenging diagnosis, and review the literature.
Janik Martin M Institute of Forensic Medicine and Medicolegal Expertises, Jessenius Faculty of Medicine, Comenius University, University Hospital, Martin, Slovak Republic. Electronic address: - - 2014
Spontaneous hemothorax is a well-known yet seldom-reported entity in forensic literature. While trauma-related hemothorax is frequently encountered in a medicolegal setting, non-traumatic and spontaneous hemothorax are relatively uncommon entities. The wide range of causes that can trigger fatal intrathoracic bleeding include thoracic aortic dissection, followed by vascular malformations, various oncological ...
Mukherjee Anirban A Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, - - 2013
Erdheim-Chester disease (ECD) is a rare non-Langerhan's cell histiocytosis affecting multiple organ systems. The most common systemic manifestations are bone lesions, infiltration of the pituitary stalk sometimes leading to diabetes insipidus, pulmonary fibrosis, cardiac failure and exophthalmus. Neurological symptoms as the first clinical manifestations of ECD have been reported in ...
Rizkallah Jacques - - 2013
Eosinophilic myocarditis is a rare and often under-diagnosed subtype of myocarditis with only around 30 cases published in the medical literature. In this article we present two patients with eosinophilic myocarditis with the aim to demonstrate the often elusive nature of the disease and present the current scientific literature on ...
Mankovecky Michael R MR Postgraduate Year III Resident, Gundersen Medical Foundation, La Crosse, - - 2013
Septic arthrosis of the ankle is a rare, often devastating, infection, with a high potential for morbidity and mortality. Delay in treatment can lead to cartilage erosion, painful synovitis, and osteomyelitis. Septic ankle arthrosis deserves prompt recognition and intervention. However, quality, sound, protocol-directed arthroscopic treatment of septic ankle arthrosis of ...
Iqbal Saima - - 2013
This is the report of a case of methotrexate nephrotoxicity for which glucarpidase was used. We use the case to review a number of teaching points related to this new treatment option.
Jiang Yajian Y Department of Hematology, Bone Marrow Transplant Center, The First Affiliated Hospital of Zhejiang University Medical School, Hangzhou, Zhejiang 310003, P.R. China ; Program in Clinical Medicine, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310029, P.R. - - 2014
Neutropenia is a common side-effect in hyperthyroid patients with long-term use of antithyroid drugs. This may be caused by drug-induced immune dysfunction or increased thyroxine hematologic toxicity, which usually returns to normal after medication is discontinued or the hyperthyroidism becomes well controlled. However, hyperthyroidism with pancytopenia is extremely rare. The ...
Bagley Jacob H - - 2013
Arachnoiditis ossificans is a rare disorder characterized by the development of calcifications of the arachnoid membrane of the thoracic and lumbar spines. It is an extremely rare cause of spinal canal stenosis and consequent neurological compromise, and its origins and optimal management remain unclear. We review of the literature that ...
Zawawi Faisal F Department of Otolaryngology - Head and Neck Surgery, McGill University, Montreal, QC, Canada; King Abdulaziz University, Jeddah, Saudi Arabia. Electronic address: - - 2013
Castleman's Disease is a rare lymphoproliferative disorder. In the literature, only 29 cases, associated with the neck presentation in children, have been reported. This is another case report regarding a 5-year old child who presented with a persistent cervical lymphadenopathy. Final pathology, after undergoing exploratory neck dissection and surgical excision, ...
Matano Fumihiro - - 2013
Cases of moyamoya disease or intracranial arterial stenosis around the circle of Willis (M/IAS) associated with hyperthyroidism have been reported. However, most of these previous reports were of the ischemic form of M/IAS and primary hyperthyroidism. To the best of our knowledge, no studies have documented therapy for M/IAS associated ...
Hu Jinwei J Department of Otolaryngology - Head & Neck Surgery, United - - 2013
Intranasal glial heterotopia is an uncommon congenital nasal lesion of neuroectoderm origin. Involvement of the parapharyngeal space is extremely rare. We present a case report of a newborn with life-threatening respiratory distress and feeding difficulty caused by a nasal glial heterotopia in a rare location involving the nasopharynx and parapharyngeal ...
Wallace Zachary S ZS Division of Allergy, Immunology, and Rheumatology, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, - - 2013
IgG4-related disease (IgG4-RD) is an inflammatory disorder responsible for fibrosing, tumefactive lesions that can involve the lacrimal gland as well as the extraocular muscles, orbital soft tissues, sclera, and local nerves. We reviewed IgG4-related ophthalmic disease (IgG4-ROD), including the natural history, pathology, and treatment, based on our center's experience and ...
Yeoh Ester Chai Kheng - - 2013
The cribriform morular variant of papillary thyroid carcinoma (CMV-PTC) is a rare morphologic entity that is associated with familial adenomatous polyposis (FAP). We report a case of a young lady with an incidentally discovered right-sided neck nodule on ultrasonography with a diagnosis of CMV-PTC confirmed on thyroidectomy and review the ...
Harvey Aaron M - - 2013
Context.-The current study compares data from our hospital system before and after the 2008 implementation of the Bethesda System for Reporting Thyroid Cytology (BSRTC). Objective.-To show the effects the BSRTC has had on the reporting rates and outcomes for thyroid lesions. Design.-A search for thyroid fine-needle aspiration biopsies (FNABs) was ...
Leiser Yoav Y Clinical Instructor, Technion Faculty of Medicine, Department of Oral and Maxillofacial Surgery, Rambam Medical Center; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Electronic address: - - 2013
Controversies exist in the current literature regarding the treatment of lymphoepithelial carcinoma (LEC). The presented study summaries the literature controversies in the treatment of LEC and present a case of a rare LEC diagnosed in the sublingual gland of an otherwise healthy 21-year-old Arab woman. The patient was admitted for ...
Maraj Amisha - - 2013
Thyroid abscesses are rare, and Staphylococcus aureus is the main causative organism. Abscesses caused by other organisms are even rarer. This report describes a case of salmonella thyroiditis in an HIV-positive patient. Fine-needle aspiration cytology was performed and Salmonella sp. were cultured. The patient was successfully treated with antibiotics and incision and ...
Colletti Giacomo - - 2013
To review the literature on vascular malformations and to clarify their diagnosis, clinical presentation, and treatment options. The authors reviewed the current literature on vascular malformations looking for more innovative and credited diagnostic criteria and treatment protocols. The review is divided in 4 sections (capillary, venous, arteriovenous, and lymphatic malformations). ...
Mehta Rohtesh S - - 2013
Hemophagocytic lymphohistiocytosis (HLH) is a rare disease in children and an exceptionally rare occurrence in adults. It is categorized broadly into primary (familial) or the secondary types; the latter being associated most commonly with an underlying malignancy. HLH carries a high rate of mortality, and the treatment itself is associated ...
Zhao Wenxue - - 2013
Pegylated interferon alpha (Peg IFN-α) in combination with ribavirin is the backbone of treatment in chronic hepatitis C (CHC). Cardiotoxicity due to interferon therapy is rare. The most frequent cardiovascular complications are arrhythmias and ischemic manifestations. Cardiomyopathy is extremely rare but can be life threatening. We present the case of ...
Triggiani Vincenzo - - 2013
The clinical occurrence of ectopic thyroid gland is an infrequently encountered condition, resulting from the developmental abnormality during the migration of the thyroid anlage from the floor of the primitive foregut to its final position in the neck. It can be found along the way of thyroid descent, in the ...
Farhat Nada A - - 2013
Mucoepidermoid carcinoma is the most common salivary gland malignancy and it may arise anywhere that salivary tissue is present. Mucoepidermoid carcinoma has been reported to arise de novo within the thyroid gland, and here, we describe three cases of primary mucoepidermoid carcinoma of the thyroid, including clinical presentation, diagnostic evaluation, ...
Johnston Peter S - - 2013
Os acromiale is a common finding in shoulder surgery. We review the anatomy, prevalence, pathophysiology, and treatment options for this diagnosis. In addition, we report on a case series of 6 patients with a symptomatic meso os acromiale who were treated with a new technique involving arthroscopic acromioplasty in conjunction ...
Park Tina Keun Nan - - 2013
Cleidocranial dysplasia (CCD), an autosomal dominant disorder with a prevalence of 1 in 1,000,000 individuals, is mainly caused by mutations in Runx2, a gene required for osteoblastic differentiation. It is generally characterized by hypoplastic clavicles, narrow thorax, and delayed or absent fontanel closure. Importantly, its orofacial manifestations, including midfacial hypoplasia, ...
Agarwal Vratika - - 2013
Floating right heart thrombus, also known as "emboli in transit" is a potentially fatal condition, which may be attributed to several different etiologies and usually co-exists with massive pulmonary embolism. Although, the mortality rate is as high as 40%, there are no therapeutic guidelines established. A case is presented of ...
Upadhyay Jagriti - - 2013
Objective: We report a case of thyrotoxicosis following minimally invasive parathyroidectomy.Methods: Case report with review of literature.Results: A 70-year-old woman with primary hyperparathyroidism developed thyrotoxicosis 2 weeks following minimally invasive radio-guided parathyroidectomy. The diagnosis of post-parathyroidectomy thyrotoxicosis (PTT) was made after excluding other causes of thyrotoxicosis. She reverted back to ...
Zaman Rashid - - 2013
This short paper reviews the case for the use of Transcranial magnetic stimulation in the treatment of Adult-ADHD, summarising present knowledge and making the case for future studies.
Shah Mamta - - 2013
Thyrotoxic Hypokalemic Periodic Paralysis (THPP) is a rare complication of thyrotoxicosis and can sometimes be fatal. It needs early recognition for proper management and prevention of recurrences. Here we describe two cases presenting with acute onset of paresis, low potassium levels, low levels of thyroid-stimulating hormones (TSH), and elevated thyroid ...
Hong Jae Won JW Division of Endocrinology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, - - 2013
Acromegaly is a slowly progressive disease caused by excessive growth hormone (GH), which is related to a GH secreting pituitary tumor in most cases. Herein, we describe the epidemiology, clinical characteristics, and treatment of acromegaly in Korea with a literature review. The average annual incidence of acromegaly in Korea was ...
Hunn Benjamin H M - - 2013
Idiopathic granulomatous hypophysitis (IGH) is a rare inflammatory disease of the pituitary. There is debate in the scientific literature as to whether IGH represents a continuum of disease with lymphocytic hypophysitis or has a distinct pathogenesis. Due to the rare nature of the disease, previous descriptions have been limited to ...
Kim Young-Kyun - - 2013
Adventitial cystic disease of the common femoral vein is a rare condition. We herein report the case of a 50-year-old woman who presented with painless swelling in her left lower leg that resembled deep vein thrombosis. She underwent femoral exploration and excision of the cystic wall. The presentation, investigation, treatment, ...
Raghunath B V - - 2013
Skip segment Hirschsprung's disease is a condition where an area of normally ganglionated intestine is interspersed proximally and distally by aganglionic segments. The occurrence of skip segment has no clear embryological explanation, contrary to the present concept of failure of cranio-caudal migration of neural crest-derived cells in Hirschsprung's disease. Only ...
Blackburn Spiros L - - 2013
The use of Onyx has become the mainstream for the treatment of cranial dural arteriovenous fistulas (AVFs) and arteriovenous malformations, but the reported success for type I spinal dural arteriovenous fistulas (sDAVFs) remains limited. We review our experience with Onyx and report its limitations in the treatment of spinal AVFs. ...
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