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Wojtowicz Jeremy M - - 2014
ABSTRACTPurpura fulminans is a rare complication of septic shock, often associated with Streptococcus pneumoniae. Patients with anatomic or functional asplenia are at increased risk for infection because of impairment of their ability to defend against encapsulated pathogens. We report the case of a previously healthy, unimmunized 33-year-old female with functional ...
Li X-Y XY Department of Nephrology, University of Hong Kong Shenzhen Hospital, Shenzhen, - - 2014
Transverse myelitis (TM) is a relatively infrequent but severe complication in systemic lupus erythematosus (SLE). Owing to its rarity and unfavorable outcome, we investigated its general features on MRI and incidence in the context of lupus activity, to facilitate early recognition and treatment. We report a case of a young ...
Oda Ryo R Department of Orthopaedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , Kyoto , - - 2014
Spontaneous flexor tendon rupture is an unusual complication of systemic lupus erythematosus (SLE) and has not previously been reported. While tendon ruptures in association with SLE have been focused on the previous studies, upper extremity tendon ruptures are infrequently reported in the literature. Here, we present an uncommon case of ...
Shen Yi Y Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education and Chinese Ministry of Public Health; Department of Cardiology, Qilu Hospital, Shandong University, Jinan, - - 2014
We report a case of amiodarone-induced epididymitis and review the pertinent literature. This disease is currently a diagnosis of exclusion and is believed to be self-limiting. We found new evidence for the pathological diagnosis and identified amiodarone-like crystals in the epididymis as a pathological mechanism of this disease. This case ...
Chowdhury Mohammed Andaleeb MA Department of Internal Medicine, University of Toledo, Toledo, - - 2014
Neurotoxicity can develop as a side effect of intravenous acyclovir use in patients with renal impairment. It is underreported in clinical practice and often confused with worsening herpes encephalitis. We present a 69-year-old woman with end-stage renal disease on hemodialysis with acyclovir neurotoxicity treated with daily extended hemodialysis sessions. Daily ...
Northrop Michael S MS Department of Pediatrics, Vanderbilt University Medical Center, Nashville, - - 2014
Ceftriaxone is a frequently used empiric antibiotic in children. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with a high mortality rate. A 14-year-old boy suffering from Crohn disease developed bacterial pneumonia that was treated with ceftriaxone. We report successful management of ceftriaxone-induced hemolytic anemia (CIHA) in ...
Litjens Ruud P W RP Neurotoxicology Research Group, Toxicology Division, Institute for Risk Assessment Sciences (IRAS), Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80177 NL-3508 TD Utrecht, The Netherlands; Drug Monitoring, Netherlands Institute of Mental Health and Addiction, P.O. Box 725, NL-3500 AS Utrecht, The - - 2014
Hallucinogen persisting perception disorder (HPPD) is a drug-induced condition associated with inaccurate visual representations. Since the underlying mechanism(s) are largely unknown, this review aims to uncover aspects underlying its etiology. Available evidence on HPPD and drug-related altered visual processing was reviewed and the majority of HPPD cases were attributed to ...
Schjelderup P P Department of Nephrology, Aalborg University Hospital, Mølleparkvej 4, 9000, Aalborg, Denmark, - - 2014
We present a report of what we believe was an extremely rare case of hyperacute respiratory failure caused by first time exposure to cyclophosphamide in a 40-year-old woman with systemic lupus erythematosus. The patient was extensively evaluated for alternative etiologies with negative results. Treatment with methylprednisolone and high doses of ...
Abrahams Joshua M JM Resident, Department of Oral and Maxillofacial Surgery, Nova Southeastern University College of Dental Medicine and Broward Health Medical Center, Fort Lauderdale, FL, USA. Electronic address: - - 2014
Radiation-induced sarcomas of the head and neck are rare and tend to occur decades after treatment. We report a case of rapid-onset postchemoradiotherapy rhabdomyosarcoma of the maxillofacial region and briefly review the literature.
Beynat-Mouterde Caroline C CHU Le Bocage, Dijon, - - 2014
To the Editor:We identified six patients with clinical, radiographic and physiological features typical of pleuroparenchymal fibroelastosis (PPFE). In the six cases, PPFE may have been causally related to prior alkylating drugs used to treat malignacy, namely cyclophosphamide in five of the cases and carmustine (BCNU (1,3-bis-(2-chloroethyl)-1-nitrosourea)) in one. Based on ...
Aynalı Giray G Department of Otolaryngology, Medical Faculty of Süleyman Demirel University, 32200 Çünür, Isparta, Turkey. - - 2014
Hemangiomas are the most common masses of the major salivary glands in parotid glands in childhood particularly. They occur more frequently in the parotid gland and rarely the submandibular gland. Changes in blood flow dynamics within hemangiomas may induce thrombus formation and phleboliths. Cavernous hemangioma may lead to thrombophlebitis in ...
Haddad Housam H Staten Island University Hospital, 475 Seaview Ave, Staten Island, NY 10305, United States. Electronic address: - - 2014
Bendamustine is an alkylating agent approved for the treatment of chronic lymphocytic leukemia (CLL) and B-cell non-Hodgkin lymphoma. There are scant reports on bendamustine-induced immune hemolytic anemia occurring mainly in CLL patients. We report a case of immune hemolytic anemia that developed after exposure to bendamustine in a 70-year-old female ...
Fallahi Sasan S Internal Medicine Division, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran and Rheumatology Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. - - 2014
This paper presents a 54-year-old female with lupus whom severe anaemia due to pure red cell aplasia (PRCA) was the first manifestation. There was seven years interval between PRCA onset and diagnosis of lupus. Thymectomy due to thymoma had been carried out six years before but anaemia sustained. Hypothyroidism and ...
Kaloshi Gentian G Department of neurosurgery, University Hospital Center "Mother Theresa", Tirana, - - 2014
Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, ...
Pecker Lydia H LH Children's National Medical Center, Division of Oncology, Center for Cancer and Blood Disorders, 111 Michigan Avenue, NW, Washington, DC, 20010, USA, - - 2014
All-trans retinoic acid (ATRA), a component of standard therapy for acute promyelocytic leukemia (APL), is associated with potentially serious but treatable adverse effects involving numerous organ systems, including rare skeletal muscle involvement. Only a handful of cases of ATRA-induced myositis in children have been reported, and none in the radiology ...
Taneja Atul K AK Musculoskeletal Radiology Division, Imaging Department, Hospital Israelita Albert Einstein, São Paulo, Brazil, 05652-900, - - 2014
We report a rare case of Kager's fat pad atrophy and fibrosis in a 60-year-old woman 1 year after a steroid injection for Achilles tendinopathy. There are few published reports of steroid-induced atrophy affecting deeper layers of fat tissue. To our knowledge, this case report is the first to illustrate its ...
Doshi Rishi R RR The Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, - - 2014
To present 3 cases of tamoxifen-induced foveal cavitation and review previous prospective and cross-sectional studies. Observational case series. Retrospective analysis of patients presenting to a single institution with evidence of tamoxifen-induced maculopathy. Three patients presented with pseudocystic foveal cavitation similar in appearance to macular telangiectasia type 2 on spectral domain ...
Geoffroy Pierre Alexis PA The University of Lille Nord de France, F-59000 Lille, France (PAG, RB, OC, BR)?>; Department of Psychiatry, Centre Hospitalier Universitaire de Lille (CHRU), F-59037. Electronic address: - - 2014
The gamma-aminobutyric acid type B receptor agonist baclofen is approved for spasticity and is used off-label for diverse types of addictive disorders, notably alcohol dependence. Baclofen may induce numerous neuropsychiatric adverse drug reactions, including behavioral disinhibition. However, this precise adverse drug reaction has never been assessed using either a validated ...
Forcello Nicholas P NP 1School of Pharmacy, University of Saint Joseph, Hartford, CT, - - 2014
Oxaliplatin is a third-generation platinum antineoplastic agent that commonly causes diarrhea, nausea, vomiting, myelosuppression, and peripheral neuropathy. Less common adverse effects that are increasingly being reported include acute immune-mediated thrombocytopenia, hemolytic anemia, and pancytopenia. Here, we report a patient case of suspected oxaliplatin-induced immune-mediated thrombocytopenia and a thorough literature evaluation ...
Slater Lee-Anne LA Interventional Neuroradiology Unit, Department of Diagnostic Imaging, Monash Medical Center; Melbourne, Australia - - - 2014
Muslin-induced foreign body granulomas are rare delayed complications after wrapping of intracranial aneurysms. Few small case series have been reported, with a paucity of documented MRI findings. In addition, there are no reports on long-term radiological appearances or temporal evolution of conservatively managed patients. We thus report on the long-term ...
Ito Takamichi T Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, - - 2014
Chronic expanding hematoma (CEH) is a rare, slow-developing disease that occurs months to years after trauma or surgery. Most CEH in soft tissue occurs in the thigh or upper extremities and can occur with or without an inducible cause. Ninety-one cases of CEH in soft tissue have been reported previously ...
Internullo M M Department of Public Health and Infectious Diseases, "Sapienza" University of Rome, Rome, Italy. - - 2014
Hydroxyurea is a cytotoxic agent widely used in the treatment of myeloproliferative disorders. It is considered a-well-tolerated antineoplastic drug, with a dose-related bone marrow suppression as main adverse effect. This report describes a patient with essential thrombocythemia who developed an interstitial pneumonitis and respiratory failure within 4 years from beginning ...
Singh Shivinder S Department of Anesthesiology and Critical Care, Armed Forces Medical College, Pune, Maharashtra, - - 2014
Two cases of Acquired Methemoglobinemia are presented. The significance of a high index of suspicion for diagnosisis emphasized, especially in the presence of a "saturation gap". The various causes of acquired methemoglobinemia are enumerated and the management reviewed.
Shafqat Hammad H 0000-0001-5842-4322 Memorial Hospital of Rhode Island, 111 Brewster Street, Pawtucket, RI 02860, USA ; The Warren Alpert Medical School of Brown University, Providence, RI 02912, - - 2014
Chlorambucil is an alkylating agent commonly used in treatment of chronic lymphocytic leukemia (CLL). We report a case of interstitial pneumonitis developing in an 83-year-old man 1.5 months after completing a six-month course of chlorambucil for CLL. The interstitial pneumonitis responded to therapy with prednisone. We performed a systematic review ...
Eskazan Ahmet Emre AE Division of Hematology, Department of Internal Medicine, Cerrahpasa Faculty of Medicine, Istanbul University, - - 2014
Brucellosis is a worldwide zoonotic disease associated with hemolytic complications, including thrombotic microangiopathy (TMA) and hemolytic anemia. Autoimmune hemolytic anemia (AIHA) is a rare clinical presentation of this disease. In this report, we describe the cases of two patients with brucellosis who presented with Coombs-positive AIHA. We also include a ...
Kim Kyung Soo - - 2014
Concha bullosa is characterized by pneumatization of the middle turbinate and is one of the most common variations of the sinonasal anatomy. It is most often asymptomatic. A fungus ball in the concha bullosa is extremely rare, with only two reported cases in the English literature. This article describes a ...
Pothineni Naga Venkata NV Departments of 1Internal Medicine and 2Cardiology, University of Arkansas for Medical Sciences, Little Rock, - - 2013
Eptifibatide is a commonly and widely used drug for management of acute coronary syndrome and during percutaneous coronary intervention. It is usually well tolerated with no major adverse effects. We report a rare case of life-threatening thrombocytopenia secondary to eptifibatide along with a literature review of available evidence.
Tan Seng Kiong - - 2013
Objective : To present a case of pituitary apoplexy secondary to thrombocytopenia associated with dengue hemorrhagic fever (DHF).Methods : In this case study we review the presentation, evaluation, diagnosis and management of a case of pituitary apoplexy in the setting of DHF. We also searched the literature for cases of ...
Ozkol Hatice Uce HU Department of Dermatology, Faculty of Medicine, Yuzuncu Yil University, Van, - - 2013
Chemotherapy-induced acral erythema (CIAE) is a cutaneous response to diverse chemotherapeutic drug administration. These drugs cause symmetrical and painful erythema of palmoplantar surfaces. Bulla formation, desquamation, and subsequent reepithelialization may occur. Commonly, the lesions slowly resolve over 7-15 days, through desquamation, followed by regeneration of the skin. Here, we described ...
Kosgallana Athula D AD Athula D Kosgallana, Shreyashee Mallik, Vishal Patel, Department of Neurology, Liverpool Hospital, Liverpool, NSW 2170, - - 2013
We report a case of heat stroke induced acute cerebellar dysfunction, a rare neurological disease characterized by gross cerebellar dysfunction with no acute radiographic changes, in a 61 years old ship captain presenting with slurred speech and gait ataxia. A systematic review of the literature on heat stroke induced cerebellar ...
Harnett David T DT Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: - - 2013
The presentation of drug-induced lupus erythematosus (DILE) is typically mild, with a significantly lower incidence of life-threatening end-organ dysfunction relative to idiopathic systemic lupus erythematosus. DILE is an uncommon cause of cardiac tamponade but has been reported in patients treated with procainamide, isoniazid, hydralazine, sulfasalazine, and carbamazepine. We present a ...
Ganesan Sivaraman S Fellow in Head and Neck, Department of Surgical Oncology, Regional Cancer Center , Trivandrum, India - - 2013
Radiation - Induced Sarcomas(RIS) are rare clinical entity. They arise from the previously irradiated areas with a prolonged latency period. In this case report we present a rare case of radiation induced sarcoma with a brief review of literature. We report radiation-induced sarcoma in a 67-year-old male, involving the left ...
Unterstell Natasha N Rio de Janeiro State University, Pedro Ernesto University Hospital, Dermatology Program, Rio de JaneiroRJ, - - 2013
The antagonists of tumor necrosis factor alpha (TNF-α) are increasingly being used in the treatment of inflammatory and autoimmune diseases. Several adverse effects of these drugs have been reported, including the paradoxical development of sarcoidosis, especially with the use of etanercept. We present the first Brazilian case report of systemic ...
Desborough M J - - 2013
To review the incidence and clinical features of intravenous immunoglobulin (IVIg)-induced haemolysis. Haemolysis can be a severe complication of IVIg administration. It is due to the passive transfer of blood group antibodies and may result in significant anaemia and renal failure. We report a case of severe IVIg-induced haemolysis; review ...
Tarantino Roberto - - 2013
There are only three cases of arachnoid cysts inducing twelfth nerve paresis described in English medical literature. We herein report one more instance. Six weeks after surgery, the patient has almost fully recovered. This case underlines the importance of considering the arachnoid cyst as a possible cause of twelfth nerve ...
Johnson Adam S - - 2013
A three year old male from the Democratic Republic of the Congo was admitted to Monroe Carell Jr. Children's Hospital at Vanderbilt with a 10-day history of fever, emesis, and diarrhea. Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale. Immunohematology ...
Skeik Nedaa - - 2013
Congenital anomalies of the inferior vena cava (IVC) are rare and are estimated to be present in 0.07-8.7% of the general population. IVC agenesis (IVCA) is found in approximately 5% of cases of unprovoked lower extremity deep vein thrombosis in patients <30 years of age. Renal vein thrombosis (RVT) is an ...
Dos Santos Lucas Vieira - - 2013
Imatinib mesylate represents a revolution in the management of patients with metastatic gastrointestinal stromal tumors (GISTs). More recently, postoperative imatinib has been shown to improve both disease-free and overall survivals in patients with a high risk of recurrence. This article presents a well-documented case of a patient with painful and ...
Kulkarni Ranganath R RR Department of Psychiatry, SDM College of Medical Sciences and Hospital, Dharwad, Karnataka, - - 2013
Linezolid is a synthetic antimicrobial agent of the oxazolidinone class with weak, nonspecific inhibitor of monoamine oxidase enzymes. Concomitant therapy with an adrenergic or serotonergic agent or consuming tyramine (>100 mg/day) may induce serotonin syndrome (SS). We present a case report of near-fatal adverse interaction between linezolid and escitalopram inducing ...
Zwank Michael D - - 2013
Ischemic strokes in children and young adults are fortunately rare. Contrasted with adult ischemic strokes, pediatric stroke etiologies vary greatly and are often unknown. Childhood lacunar strokes and trauma-induced strokes represent particularly uncommon subsets and have been reported infrequently in the literature. It is unique to find a combination of ...
Yeter Kc - - 2013
Azathioprine-induced aplastic anemia and fatal myelosuppression is a rare occurrence in patients with systemic lupus erythematosus (SLE). We report a case of a 53-year-old female with a normal thiopurine S-methyltransferase (TPMT) level who developed aplastic anemia within 4 weeks of azathioprine initiation, resulting in death. Physicians should be vigilant in ...
Slae Mordechai - - 2013
Systemic lupus erythematosus (SLE) occurs more commonly in females than in males. Recent evidence suggests that genetic factors transmitted by the X-chromosome may confer increased risk for autoimmune disease in general, and for SLE in particular. It is therefore possible that X-chromosome polysomy might confer further increased risk for lupus. ...
Wiznia Lauren E LE Department of Dermatology, Yale University School of Medicine, New Haven, - - 2013
Several chemotherapeutic agents have been reported to induce subacute cutaneous lupus erythematosus (SCLE). To our knowledge, this is the first report to date of SCLE induced by monotherapeutic gemcitabine hydrochloride and includes a comprehensive review of all published cases of chemotherapeutic drug-induced SCLE. We describe a patient who developed a ...
Teah Melvin J - - 2013
This is a case study of a patient with multiple myeloma presenting with bisphosphonate-associated osteonecrosis of the jaw after an extraction of tooth #18 while receiving intravenous bisphosphonates. The class of drugs known as bisphosphonates is discussed. The patient's presenting signs and symptoms are reviewed. Bisphosphonate induced osteonecrosis definition, management ...
Malinvaud David - - 2013
Bamboo nodules of the glottis are of late being described as a distinct entity seen in patients with autoimmune diseases. We report the symptoms, clinical features, and management of a case of bamboo nodules of the glottis in a patient with systemic lupus erythematosus. We discuss the pathogenesis and management ...
Stuhec Matej - - 2013
Solifenacin-induced cognitive adverse effects have not been reported frequently, but solifenacin-induced delirium and hallucinations with successful switching to darifenacin, without additional drug, have not been reported in the literature. In this case report, we present an 80-year-old Caucasian male with insomnia and anxiety symptoms and overactive bladder who developed delirium ...
Wood N H - - 2013
Patients with oculocutaneous albinism are more prone to sun-induced damage due to the lack of melanin. Actinic cheilitis is a potentially malignant disorder that occurs due to chronic UV-B radiation to the vermillion region of the lip, a region that is already at risk due to its morphology. A case ...
Kumar Kamal K Department of Anesthesia, Schulich School of Medicine, London Health Sciences, Victoria Hospital, London, Ontario, - - 2013
Pruritus is a troublesome side-effect of neuraxial (epidural and intrathecal) opioids. Sometimes it may be more unpleasant than pain itself. The prevention and treatment still remains a challenge. A variety of medications with different mechanisms of action have been used for the prevention and treatment of opioid-induced pruritus, with mixed ...
Copeland William R - - 2013
Objective We report a case of spontaneous thrombosis of an extremely complex dural arteriovenous fistula (DAVF), believed to be previously incurable, after the development of a radiation-induced meningioma resulting from prior attempts to treat the fistula with radiosurgery.Methods A very large DAVF was treated over the course of 3 decades ...
Benson Brian C - - 2013
GOALS:: The objective of this study was to better understand the presenting signs and symptoms of angiotensin converting enzyme (ACE) inhibitor-induced gastrointestinal angioedema, review the medical literature related to this condition, and bring this diagnosis to the attention of clinicians. BACKGROUND:: Angioedema occurs in 0.1% to 0.7% of patients treated ...
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