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Liu Hongyun H Department of Pathology, Municipal Hospital, Qingdao University Medical College, Qingdao, Shandong 266071, P.R. - - 2014
Epithelioid angiosarcoma (EAS) is a rare disease which presents a great diagnostic challenge. The present study reports a case of EAS in the kidney in a 75-year-old male who presented with gross hematuria. An abdominal computed tomography scan revealed space-occupying lesions of the right kidney and renal cell carcinoma was ...
Chen Hua H Department of Surgical Oncology (Interventional Therapy), Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. - - 2014
Hepatocellular carcinoma (HCC) is a globally common neoplasm, with regional metastasis associated with >50% of the tumors. Extrahepatic metastasis is also common, with the lungs, diaphragm, abdominal lymph nodes and bone being the most frequently affected regions. However, to the best of our knowledge, HCC metastasis to the lacrimal gland ...
Mandato Vincenzo Dario VD Unit of Obstetrics and Gynaecology, IRCCS-Arcispedale Santa Maria Nuova, Reggio Emilia, Italy - - 2014
Primary diffuse large B-cell lymphoma of the cervix is a very rare disease, with non-specific clinical presentation. Its prognosis depends on accurate and timely diagnosis and therapy. Moreover, the management of this tumour has never been standardized. Herein we present a rare case of primary diffuse large B-cell lymphoma of ...
Sanders Brian P BP From the Wake Forest University School of Medicine, Winston-Salem, NC, - - 2014
We report the sixth case of osseous metaplasia that has occurred in the last 5 years, after a deceased-donor renal transplant was performed on a young man. While its clinical significance is unclear and probably irrelevant, osseous metaplasia is one of the most relevant principles of regenerative medicine, where every ...
Magnoli Francesca F Department of Surgical and Morphological Sciences, University of Insubria , Varese , Italy - - 2014
Abstract Metastases to the pituitary occur more frequently in patients with widespread cancer and mainly involve the posterior lobe. A few cases of metastatic carcinoma to a pituitary adenoma have been described so far. Here, the authors present an additional case of a clear cell renal cell carcinoma (CCRCC) metastatic ...
Zhang Gui-Ming - - 2014
Desmoplastic small round cell tumor (DSRCT) is an uncommon and highly aggressive malignancy with undetermined histogenesis and poor prognosis. To date, no case of testicular DSRCT has been reported in the literature.Case: A 42-year-old Chinese man presented with painless swelling of his left testis and a painless palpable nodule in ...
Watanabe Kenichi K Department of Otolaryngology, Sendai Social Insurance Hospital, Sendai, Japan Department of Otorhinolaryngology-Head and Neck Surgery, Tohoku University School of Medicine, Sendai, Japan - - 2014
Clear cell carcinoma (CCC) is a rare, low-grade malignant neoplasm of minor salivary glands. Clear cell carcinoma is composed of monomorphic clear cells that contain glycogen within a hyalinized stroma. The microscopic diagnosis can be challenging, and the treatment strategy has not been established. We report a case of a ...
Tong Liping L Department of Thoracic Surgery, Tangdu Hospital of the Fourth Military Medical University, Xi'an, Shaanxi 710038, P.R. - - 2014
Malignant fibrous histiocytoma (MFH) is rare in the chest wall, particularly in patients who have undergone radiotherapy for primary nasopharyngeal cancer. In the present study, a case of MFH of the upper chest wall that appeared four years after initial radiotherapy for squamous cell carcinoma of the nasopharynx is reported. ...
Wong W K WK Department of Otolaryngology,North Shore Hospital,Auckland,New - - 2014
Background: Immunoglobulin G4 related disease is an inflammatory condition characterised by the presence of fibrotic lesions infiltrated by immunoglobulin G4 positive plasma cells. It can arise from almost any region of the body and it is being increasingly recognised in the head and neck. Regardless of the site of involvement, ...
Mishra Sudhansu Sekhar SS Department of Neurosurgery, Shrirama Chandra Bhanj Medical College and Hospital, Cuttack, Odisha, - - 2014
Cerebellar glioblastoma multiforme (GBM) is a rare tumor that accounts for only 1% of all cases of GBM and its giant cell variant is even much rarely encountered in adults. A case of cerebellar giant cell GBM managed at our institution reporting its clinical presentation, radiological and histological findings, and ...
Hamman Michael Shane MS *Both authors are affiliated with the Division of Dermatology, San Diego Medical Center, University of California, San Diego, - - 2014
Trichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm with outer root sheath differentiation. Most cases have been treated by surgical excision with a few recurrences. There have been 6 case reports of TC treated with Mohs micrographic surgery (MMS). To perform an updated review of the literature regarding management ...
Kang Sun-Young SY Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, - - 2014
Congenital leukemia is very rare, and its prevalence according to recently published papers is from 1 to 5 per million live births. This can be often diagnosed in postpartum throughout bone marrow biopsy, showing abnormal proliferation of immature blasts and granulocytic precursors. Hepatosplenomegaly is the most common feature which is ...
Faye-Petersen Ona Marie OM a University of Alabama at Birmingham, Department of Pathology (NP - - 2014
Abstract We report a case of a Trisomy 21 male newborn with transient abnormal myelopoiesis (TAM) at birth whose placenta showed extravasated fetal blasts in the perivillous (maternal) space. Concern for possible maternal spread of fetal malignancy prompted a Kleihauer-Betke test and flow cytometric analysis of the maternal peripheral blood, ...
Glicksman Jordan T - - 2014
Objectives: Metastasis of laryngeal squamous cell carcinoma (SCC) to the intra-abdominal gastrointestinal tract is exceedingly rare. The objectives of this case report are to describe a case involving a perforated metastasis of a laryngeal SCC to the ileum and to review the literature pertaining to other similar cases. A review ...
Kfoury Hala H Department of Pathology, King Saud University , Riyadh , Saudi - - 2014
ABSTRACT Background/Aim: Effacement of the epithelial cell foot processes of glomerular podocytes are thought to be diffuse in the primary form of focal and segmental glomerulosclerosis (FSGS). In contrast, effacements that occur in the secondary form of FSGS are thought to be focal. To evaluate this theory, the extent of ...
Zwerdling Ted T *Miller Children's Hospital, Long Beach †Department of Pediatrics, University of California, Irvine, CA ‡Children's Hospital of Pittsburgh of UPMC, Pittsburgh, - - 2014
Langerhans cell sarcoma is a rare malignancy with only 1 pediatric case (less than 15 y of age) reported. Here, we report the second case of Langerhans cell sarcoma in a child who presented with cord compression. This patient was treated with extensive surgical resection, postoperative chemotherapy, and involved-field radiation ...
Seifert Robert P RP Department of Pathology and Cell Biology, University of South Florida Morsani College of Medicine, Tampa, - - 2014
Myeloid sarcoma involving soft tissue is rare and may present a pathologic diagnostic challenge, particularly when it precedes or coincides with hematological malignancies. Furthermore, it may mimic non-Hodgkin lymphoma, poorly differentiated carcinoma, melanoma, or round blue cell tumors, which is a potential diagnostic pitfall. In addition to a retrospective review ...
Hamman Michael Shane MS *Both authors are affiliated with the Division of Dermatology, San Diego Medical Center, University of California, San Diego, - - 2014
Trichilemmal carcinoma (TC) is a rare malignant adnexal neoplasm with outer root sheath differentiation. Most cases have been treated by surgical excision with a few recurrences. There have been 6 case reports of TC treated with Mohs micrographic surgery (MMS). To perform an updated review of the literature regarding management ...
Cacciato Insilla Andrea A Andrea Cacciato Insilla, Monnalisa Granai, Grazia Gallippi, Daniela Campani, Department of Surgical Pathology, University Hospital of Pisa, 56124 Pisa, - - 2014
Deep infiltrating endometriosis is an often-painful disorder affecting women during their reproductive years that usually involves the structures of the pelvis and frequently the gastrointestinal tract. We present the case of a 37-year-old female patient with an endometrial growth on the sigmoid colon wall causing pain, diarrhea and the presence ...
Iori A P AP Dipartimento di Ematologia, Oncologia, Anatomia Patologica e Medicina Rigenerativa, Azienda Policlinico Umberto I, Sapienza University, Rome, - - 2014
Strongyloides stercoralis infections may be documented in low-endemicity areas, particularly in immigrants from endemic areas. The case of a patient from Bangladesh, an immigrant to Italy who developed a S. stercoralis infection after allogeneic stem cell transplant, is described, and 7 further cases are reviewed. Because of the atypical clinical presentation, ...
Hsi Eric D ED *Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH †Department of Pathology, University of California Los Angeles, Los Angeles, CA ‡Department of Anatomic Pathology ¶Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN §Department of Pathology, Brigham and Women's Hospital, Boston, MA ∥British Columbia Cancer Agency, Vancouver, BC, - - 2014
The diagnosis of peripheral T-cell and NK-cell lymphomas (PTNKCL) is difficult with few standards for required ancillary studies. We evaluated a series of PTNKCLs using a tiered approach to immunohistochemistry and molecular genetic characterization to document diagnostic accuracy and clinical relevance. Seven hematopathologists reviewed 374 cases that included PTNKCL and ...
Bedir Recep R Faculty, Department of Pathology, Recep Tayyip Erdogan University School of Medicine , Rize, Turkey - - 2014
Atypical fibroxanthoma (AFX) is a superficial variant of pleomorphic malignant fibrous histiocytoma. Clear cell atypical fibroxanthoma (CCAFXA) is a rare variant of atypical fibroxanthoma. A 74-year-old male patient presented with a rapidly growing nodule on the shoulder, which had appeared over a 5-months period. Lesion was excised by the plastic ...
Sun Yan - - 2014
Solitary metastatic renal tumors are rarely encountered. We report the case of a 63-year-old man who developed a solitary renal metastasis after undergoing an esophagectomy for esophageal squamous cell carcinoma and subsequent nephrectomy of the right kidney.
Vija Lavinia - - 2014
Testicular morphology and immunohistochemical studies have never been reported in genetically documented adult patients with 5 alpha-reductase type 2 deficiency (5alpha-R2 deficiency). We describe the testicular histopathology of a 17-year-old XY subject with 5alpha-R2 deficiency caused by the recurrent homozygous Gly115Asp loss of function mutation of the SRD5A2 gene.We also ...
Paluri Ravi R Hematology & Oncology, University of Alabama at Birmingham, AL, - - 2014
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematological malignancy derived from precursors of plasmacytoid dendritic cells. Very few cases of BPDCN have been described with lack of skin manifestations at the time of diagnosis. Here we report two rare non-cutaneous presentations of BPDCN without obvious ...
Gathings Robert R School of Medicine, University of Mississippi Medical Center, 39216 Jackson, - - 2014
Melanoma-associated leukoderma (MAL) is a relatively uncommon phenomenon in the literature that can present at various times during the detection of melanoma (e.g. before melanoma detection, after detection and before treatment, after treatment with immunotherapeutic agents). We report a case of MAL in an 83-year-old man after treatment with high ...
Walton Benjamin B Departments of Otolaryngology, University of Texas Medical Branch , Galveston, TX, - - 2014
While there is an intimate anatomical and embryological relationship between the inferior parathyroid gland and thymus, concurrent pathology is rare. Three cases have been reported in the literature of a parathyroid adenoma in conjunction with a thymoma. We present a case report of a 60-year-old female with a past medical ...
Macesic N N Victorian Infectious Diseases Service, Royal Melbourne Hospital, Parkville, Victoria, - - 2014
Prototheca species are achlorophyllus algae. Prototheca wickerhamii and Prototheca zopfii cause human disease. In immunocompetent individuals, they cause soft tissue infections and olecranon bursitis, but in transplant recipients, these organisms can cause disseminated disease. We report a fatal case of disseminated P. zopfii infection in an hematopoietic stem cell transplant (HSCT) ...
Montgomery Nathan D ND Dept of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, CB #7525, Brinkhous-Bullitt Bldg, Chapel Hill, NC 27599-7525; - - 2014
Objectives Syringomatous adenoma of the nipple (SAN) is a rare benign infiltrative neoplasm that may be confused with low-grade breast carcinomas. We report the case of 71-year-old woman with a fungating left breast mass and subareolar calcifications in the contralateral breast. Methods Histomorphologic features were evaluated with standard H&E-stained sections. ...
Zhao Jiyu J Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, P.R. - - 2014
Postoperative spindle cell nodule (PSCN) of the bladder is a rare condition. It is a type of benign lesion frequently misdiagnosed as sarcomatoid carcinoma on the basis of similar cell morphology. The present report describes a tumor affecting a 71-year-old male who had undergone three transurethral resections. Pathological results suggested ...
Pircher Andreas A Department of Internal Medicine V, Medical University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria. - - 2014
Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive subtype of peripheral T-cell lymphoma with unique clinical, pathological and genetic features. Clinical diagnosis is often hampered as typical lymphoma-associated symptoms may not be found at the time of first presentation and only occur later during disease progression. However, as AITL leads to ...
Takeuchi Satoru S Department of Neurosurgery, National Defense Medical College, Saitama, - - 2014
Hypertrophic pachymeningitis is an uncommon disorder that causes a localized or diffuse thickening of the dura mater. Recently, the possibility that IgG4-related sclerosing disease may underlie some cases of intracranial hypertrophic pachymeningitis has been suggested. We herein report the tenth case of IgG4-related intracranial hypertrophic pachymeningitis and review the previous ...
Gui Wei W Department of Hematology, Shanxi Tumor Hospital, - - 2014
To evaluate the treatment of primary pulmonary NK/T cell lymphoma. A case report and review of the literature.The tissue material was obtained by transbronchial biopsy and the diagnosis was confirmed by pathology. He received 5 cycles of chemotherapy with L-asparaginase based regimen. He remained CR for two years following the ...
Qiu Xiaoming - - 2014
Reports of primary diffuse large B-cell lymphomas of the chest wall are extremely rare in the literature. We report the case of a 62-year-old Chinese woman presenting with left-sided chest pain. A computed tomography scan showed a solid, round mass in the left anterior chest wall, involving the second and ...
Lu Lucy X LX Vanderbilt University School of Medicine, Nashville, - - 2014
IMPORTANCE IgG4-related hypertrophic pachymeningitis (IgG4-RHP) is an increasingly recognized manifestation of IgG4-related disease, a fibroinflammatory condition that can affect virtually any organ. It is estimated that IgG4-RHP may account for a high proportion of cases of hypertrophic pachymeningitis once considered idiopathic. OBJECTIVE To summarize the current knowledge on IgG4-RHP including ...
Alexander John J Department of Pathology, College of Medicine, Wexner Medical Center, The Ohio State University, 405 Doan Hall, 410 West 10th Avenue, Columbus, OH, 43210, - - 2014
We present an example of clear cell chondrosarcoma (CCC) arising in the thyroid cartilage, and review the literature regarding this neoplasm in the larynx. This patient has no evidence of disease 3 years post hemilaryngectomy. Although rare and morphologically distinct, CCC follows the same benign clinical course as conventional laryngeal chondrosarcoma.
Reiersen David A DA LSU-Shreveport HSC Department of Otolaryngology/Head & Neck Surgery, United States. Electronic address: - - 2014
Review of a case of paraosseous extramedullary hematopoiesis (EMH) affecting the maxillary sinuses and retro-orbital spaces imitating bilateral orbital cellulitis. Maxillofacial EMH causes diagnostic/therapeutic challenges. This case report describes a 4-year-old African American male with sickle cell disease (HbSS) who presented with bilateral orbitofacial swelling. Diagnosis was made with imaging ...
Bowen Joslin M JM Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, - - 2014
Few studies have examined the value of a mandatory second review of outside pathology material for haematological malignancies. Therefore, we compared diagnoses on biopsies referred to an academic medical centre to determine the rate and therapeutic impact of revised diagnoses resulting from a second review. We reviewed 1010 cases referred ...
Lladó Ana Cristina Amorim Oliveira Gaia AC Hospital Santo António dos Capuchos, Lisbon, Portugal; Centro Hospitalar de Lisboa Central, Lisbon, Portugal. Electronic address: - - 2014
Mastocytosis refers to a group of disorders characterized by the infiltration of clonally derived mast cells to the skin or extracutaneous tissues resulting in a heterogeneous clinical picture. It is a rare hematologic disorder in all its forms. The exact incidence is unknown; it affects patients of any age and ...
Harvey Nathan T NT *Department of Anatomical Pathology, PathWest Laboratory Medicine, QEII Medical Centre, Nedlands, Australia; †School of Pathology and Laboratory Medicine, University of Western Australia, Perth, Australia; ‡CliniPath Pathology, West Perth, Australia; §Healthscope Pathology, Queensland, Australia; and ¶Dermatopathology WA, Cottesloe, - - 2014
To describe the features of 4 cases of basal cell carcinosarcoma and systematically review previously reported cases. Four cases of basal cell carcinosarcoma were identified from the practice of the authors. A search of the literature revealed an additional 40 cases, variously described in small series and single case reports. ...
Lv Meiling M Department of Clinical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi 710061, P.R. - - 2014
Splenic metastasis of ovarian cancer appears to be more common in serous cystadenocarcinomas. Splenic metastasis usually occurs postoperatively and simultaneously with dissemination to the greater omentum and pelvic cavity. Compared with other ovarian cancer subtypes, ovarian clear cell adenocarcinoma (OCCA) is rare, accounting for <5% of all ovarian malignancies. OCCA ...
Lapresto Lindsay - - 2014
Porphyria cutanea tarda (PCT) is a blistering skin disorder that occurs most commonly in middle-aged individuals. It is caused by decreased uroporphyrinogen decarboxylase (UROD) activity, which results in elevated levels of uroporphyrinogen. Occurrence remains very rare in children with some sources quoting as few as 50 reports of childhood cases.1 ...
Mayson E E Haematology Department, Wollongong Hospital, Wollongong, New South Wales, - - 2014
Follicular lymphomas are the most common of the clinically indolent non-Hodgkin lymphomas. The immunophenotypic pattern of follicular lymphoma classically demonstrates the B-cell markers CD19, CD20, CD22, CD79a, surface immunoglobulin and CD10. The tumour cells are usually negative for CD5. We described two cases of CD5-positive follicular lymphoma. This finding has ...
Moriyama Shingo S Department of Urology, Saitama Red Cross Hospital, Saitama, Saitama 338-8553, - - 2014
Metastasis from renal cell carcinoma (RCC) to the testis is rare. This case report presented an extremely rare case of simultaneous bilateral testicular metastases from RCC in a 65-year-old man who had experienced indolent scrotal enlargement over a period of several months. Scrotal ultrasonography showed 4.0- and 2.0-cm-sized masses in ...
Song Jin Ho - - 2014
Mucosa-associated lymphoid tissue (MALT) lymphoma is frequently reported in the gastrointestinal tract (GIT), but the incidence is low in the upper aerodigestive tract. In particular, MALT lymphoma of the tongue is very rare. Only four cases have been reported in the English literature to date. We report a case of ...
Al-Hussain Turki T Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia, - - 2014
Follicular dendritic cell sarcoma (FDCS) of the parapharyngeal space is a rare malignant tumor. Only eleven cases of FDCS of the parapharyngeal space have been reported in English literature. Most of the reported cases developed tumor recurrence within 1 year or had metastasis. Because of the rarity of FDCS in the ...
Lee Pristine W PW Department of Dermatology, Kaiser Permanente, San - - 2014
Noninvoluting congenital hemangioma (NICH) is a distinct vascular tumor of infancy. We describe the clinical characteristics, histopathology, imaging, and natural history of NICH and compare our findings with previous reports. We conducted a retrospective review of charts and photographic databases from 2 vascular anomaly centers over a 15-year period. Thirty ...
Phillips Katherine K a University of Florida, Pathology, Immunology, and Laboratory - - 2014
Abstract We report the postmortem findings of two siblings with gross and microscopic features consistent with IMAGe association (Intrauterine growth retardation, Metaphyseal dysplasia, Adrenal hypoplasia congenita, and Genital anomalies) with an emphasis on the histopathology of the adrenal gland in this rare syndrome. The first sibling was an 8-week old ...
Takahama Ademar A - - 2014
Oral squamous cell carcinoma (SCC) is considered a primarily localized disease, and distant metastasis is not common. An increasing number of case reports involving unusual sites for distant metastasis from oral carcinoma have been reported in the literature. This is likely due to the improved control of cancer at the ...
Shahid Mohammad M Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, - - 2014
Schwannomas are benign nerve sheath tumors composed of Schwann cells, which normally produce the insulating myelin sheath covering the peripheral nerves. Common locations include the head, neck, mediastinum, and retroperitoneum. These tumors are usually asymptomatic until they become large and compress the surrounding tissues. Most schwannomas occur during the third ...
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