Propafenone hydrochloride was approved for marketing by the United States (U.S.) Food and Drug Administration (FDA) in November 1989. During U.S. clinical trials of propafenone, one case of agranulocytosis was seen. Seven additional cases have been reported outside the U.S. One German report of profound but reversible granulocytopenia appeared in ...

For 1990, the number of traffic fatalities (44,529) reported in the United States was the lowest number reported since 1985 (1). However, limited studies appear to indicate that the proportion of female drivers involved in fatal crashes and the proportion arrested for driving while intoxicated may be increasing (2-4). This ...

A publishable case report in the field of lactation consulting informs readers about some new or unexpected facet of lactation (the production of milk) or breastfeeding (the act of infant feeding). It increases our understanding of this physiological process and improves our ability to resolve breastfeeding problems. The Introduction should ...

Ainhum is the spontaneous autoamputation of toes as a result of the formation of a constricting band. It usually affects the fifth toe bilaterally and predominantly affects blacks in tropical regions, but has been uncommonly reported in temperate regions as well, including the United States. Of the 29 cases identified ...

The first cases of acquired immunodeficiency syndrome (AIDS) were reported in June 1981. From 1981 through December 1987, 50,000 AIDS cases had been reported to CDC, and by August 1989, 100,000 cases had been reported. From September 1989 through November 1991, state and territorial health departments reported 100,000 additional cases. ...

The article presents a review of current Governmental family welfare program information, education and communications (IEC) activities in Uttar Pradesh, the most populous state in India (139 million in 1991). The review is based on available literature. The extent of general outreach of mass media as well as constraints and ...

Mathematical models have projected increasing numbers of pesticide poisoning throughout the world, rising from 500,000 cases/yr in 1972 to 25,000,000 cases/yr in a 1990 estimate. Among 148 outbreaks (excluding Bhopal and three probable epidemics of pesticide-related suicide) reported between 1951-90, the known number of cases was 24,731 with 1065 deaths ...

Looking ahead to the abolition of many intra-European frontiers the Authors offer this contribution to the discussion of the medico-legal aspects of gynecological activity in the United Europe of 1993. It is to this end that they present the data from a review of the material which has been the ...

Following resurgence in Bihar of epidemic kala-azar, outbreaks of the disease were identified simultaneously in two separate foci about 500 km apart in West Bengal in 1980. While the outbreak in one of these foci, in northern West Bengal, was the result of a direct extension of the Bihar epidemic, ...

Since the Public Health Service began recording statistics on trichinosis in 1947, the number of cases reported by state health departments each year has declined. In the late 1940s, health departments reported an average of 400 cases and 10-15 deaths each year; from 1982 through 1986, the number declined to ...

From August through October 1991, three persons, one each in Texas, Arkansas, and Georgia, died from rabies. Including these three cases, 16 cases of human rabies have been reported to CDC from 1980 through 1991; seven of these are believed to have been acquired in the United States. This report ...

To define the incidence of trichinosis associated with foreign travel and characterize the epidemiologic and clinical features of cases acquired abroad, all case report forms submitted to the Centers for Disease Control through state health departments and the National Morbidity Reporting System from 1975 to 1989 were reviewed. Twenty-six cases ...

Lyme disease is a tick-borne illness that primarily occurs in the United States in three endemic areas: the northeast, upper midwest, and pacific coastal regions. Although Oklahoma is considered a non-endemic area of Lyme disease, other tick-borne infections such as Rocky Mountain spotted fever, ehrlichiosis, and tularemia occur at endemic ...

A survey has been carried out to investigate the extent of non-reporting and delayed reporting of plain radiographs in UK hospitals. The survey took the form of a confidential postal questionnaire to all consultant radiologists in the UK. Five hundred and sixty-five replies were included in the study, representing 45% ...

The number of reported cases of syphilis, including primary, secondary and congenital syphilis, has been rapidly rising since 1987. The greatest increases have occurred in urban areas. An association between human immunodeficiency virus infection and syphilis has been established. Primary syphilis is manifested by a clean, painless ulcer called a ...

Through June 26, 1991, cholera has been reported from seven countries in the Western Hemisphere: Brazil, Chile, Colombia, Ecuador, Mexico, Peru, and the United States. In the United States, a total of 14 confirmed cases of epidemic-associated cholera have been reported among persons in Florida (one) (1), Georgia (one) (2), ...

Thyrotoxic periodic paralysis (TPP) is a dramatic complication of thyrotoxicosis usually seen in young men with untreated Graves' disease. We report the case of a 29-year-old active duty man with TPP attacks atypical in that they occurred during and after resolution of the hyperthyroidism. Our literature review revealed only two ...

From June 1989 to March 1990 there were eight cases of Legionnaires' disease caused by Legionella pneumophila serogroup 1 in a renal transplant unit. There were seven cases of pneumonia and one case of pleural effusion. A study was conducted to identify the source of the outbreak. Legionella anisa was ...

Surveillance for Lyme disease (LD) was initiated by CDC in 1982 (1), and in January 1991, LD became nationally reportable (2). Forty-six states reported cases in 1989 and 1990 (Figure 1), but the occurrence in nature of the causative bacterium, Borrelia burgdorferi, has not been documented in all of these ...

In 1981, 189 cases of acquired immunodeficiency syndrome (AIDS), a newly recognized condition, were reported to CDC from 15 states and the District of Columbia; 76% of cases were reported from New York and California. Ninety-seven percent of cases reported were among men, 79% of whom reported being homosexual/bisexual (i.e., ...

As of May 10, 1991, local and state health departments reported a provisional total of 27,672 measles cases in the United States for 1990--a 52.1% increase over the 18,193 cases reported for 1989--and 89 suspected measles-associated deaths. Cases were reported from 49 states and the District of Columbia. The overall ...

Since the early 1980s the incidence of gonorrhea has been declining worldwide, as well as in Israel. This decline has been attributed to the fear of AIDS. We report an outbreak of penicillin-resistant Neisseria gonorrhoea that occurred in the last quarter of 1988 and throughout 1989 in southern Israel. During ...

In March 1990, a large measles outbreak began in New York City. Through December 1990, approximately 2500 cases and eight measles-associated deaths were reported. However, since January 1991, transmission has increased; through May 7, more than 2000 cases and nine deaths were reported to the New York City Department of ...

Through April 30, 1991, epidemic cholera has been reported from five countries in South America: Brazil, Chile, Colombia, Ecuador, and Peru. In addition, in the United States a total of 10 confirmed cases of epidemic-associated cholera have been reported in Georgia, New Jersey, and Florida. This report summarizes information regarding ...

New York State has reported more AIDS cases (26,576) through November 1989 than any other state, accounting for 23 percent of all reported cases in the nation at the time. New York City has reported 22,231 (84 percent) of the statewide cases. The epidemiology of AIDS in New York State ...

Within the United States, blastomycosis is primarily endemic in the Mississippi and Ohio River valleys, but reliable figures as to its prevalence and incidence are scarce. A review of pathology department files and medical records from three hospitals in Rockford, Illinois, revealed 32 documented cases of blastomycosis in an eight ...

From January 1 through April 19, 1991, at least nine outbreaks of rubella, involving more than 400 cases, have been reported in Amish communities in the United States. These outbreaks have been reported from Mecosta and Montcalm counties, Michigan; Allegany, Cattaraugus, Chautauqua, and St. Lawrence counties, New York; Geauga, Knox, ...

Extrophic lesions of the ventral abdominal wall are represented by a range of anomalies of which the most severe is cloacal extrophy. By 1986, only 190 cases were reported in the world literature and it is estimated that only 15 cases are seen in the United States of America per ...

On June 5, 1990, a 22-year-old man died of rabies encephalitis in Hidalgo County, Texas, along the Mexican border. This was the fourth case of human rabies known to be acquired in the United States since 1980 and the first case in Texas since 1985. This report summarizes the case ...

A total of 1,355 cases of tularemia observed between 1924 and 1987 in Japan were viewed on the basis of clinical manifestations and the results were compared with those in the United States. The incubation period varied from one day to over one month. In 75.5% of cases, the symptoms ...

Over a 3-month period, seven patients in a paediatric oncology unit developed Pseudomonas pickettii septicaemias. The outbreak was difficult to recognize since the cases occurred at widely spaced intervals and problems were experienced with the identification of the isolates. Many of the isolates were initially misidentified on the basis of ...

In the United States, occupational illness and injury cases meeting specific reporting criteria are recorded on company Occupational Safety and Health Administration (OSHA) 200 logs; case description data are submitted to participating state agencies for coding and entry in the national Supplementary Data System (SDS). We evaluated completeness of reporting ...

Measles morbidity and mortality have declined in Israel since the introduction of routine vaccination in 1967. The reported incidence of civilian cases of measles declined from 50/100,000 in 1968-72, to 27/100,000 in 1983-87. There was also a decrease from 108 to 49 measles deaths, and from 84 to 29 cases ...

Pyomyositis is a purulent infection of skeletal muscle caused predominantly by Staphylococcus aureus. Although not often encountered in the continental United States, pyomyositis is frequently seen in tropical areas. Pyomyositis is difficult to diagnose as it may mimic other diseases. Delay in diagnosis may lead to septicemia, shock, and death. ...

Between 1981 and 1989, the incidence of primary and secondary syphilis in the United States increased 34%, from 13.7 to 18.4 cases per 100,000 persons, the highest since 1949. The populations affected most by syphilis also changed substantially. From a peak of 10.0 cases per 100,000 persons in 1982, the ...

A giardiasis outbreak from a chlorinated, unfiltered surface water supply in Penticton, British Columbia (pop. 25,000) from June to August 1986 resulted in 362 laboratory-confirmed cases. A telephone survey estimated an attack rate of over 12%. A reservoir pond containing Giardia-infected beaver was implicated as the source. A case-control study ...

Rates of leprosy cases newly reporting during 1986 are examined for a region of south-eastern Nigeria. Figures reveal that in the part of the region which was designated in 1987 as a new state, half of the administrative units had new case reporting rates higher than in adjacent areas, while ...

We have studied the prevalence of an underlying myeloproliferative state in 20 patients with either hepatic or portal vein thrombosis. Using conventional clinical and laboratory criteria, an underlying myeloproliferative state was identified as the cause of the thrombosis in five patients (25%). A further 10 of the remaining 15 cases ...

Reports of melioidosis in residents of European countries are rare. We describe a case of reactivation of latent melioidosis in a United Kingdom resident. The case demonstrates the lack of clinical response to chemotherapy despite proven in vitro sensitivity of the organism to the drugs used. It is important to ...

Human infection with brucellosis appears to be very uncommon in Kentucky. Only three cases have been reported to the Kentucky Department of Health, Frankfort, in the last 4 years. It is suspected, however, that brucellosis is severely underdiagnosed and under-reported in the United States. A patient recently diagnosed with acute ...

The clinical and serologic diagnosis of syphilis in the human immunodeficiency virus-infected patient may be difficult to make. We have recently seen a case of symptomatic neurosyphilis in such a patient presenting with positive serum and CSF syphilis serology. On the basis of this case and similar cases reported in ...

An epidemiological and entomological survey was conducted in Badohi town of Varanasi district of Uttar Pradesh (India) from where an outbreak of kala-azar was reported. Serological and clinical results showed 83 cases who responded to sodium antimony gluconate. Phlebotomus argentipes and P. papatasi could be detected in area of outbreak. ...

The authors reviewed anthropological reports of skull trepanation (trephination) among the early Indians of Canada and the United States of America. Published reports of 20 trepanations in 19 skulls are reviewed. All were believed to have been performed ante mortem. Most were from the pre-Columbian era. Eleven were from Canada ...

Hansen's disease presents a large public health problem throughout much of the world but it occurs infrequently in the United States. Only 8,501 cases have been reported since 1921 and 81 percent of these have been from just six states. Typical of many states, North Carolina has had only twenty-two ...

In 1870, Ansil L. Robinson was charged with the murder of his mistress, Mary Lunsford, in Mansfield, Ohio, U.S.A. Evidence against Robinson included an attempt to match his teeth to bite marks on the victim's arm. Robinson was acquitted after a 3-week trial despite the evidence linking his teeth to ...

Primary hepatocellular carcinoma (HCC) has a high incidence rate worldwide with an extremely grave prognosis, but, fortunately, accounts for only 2% of all cancers in the United States. Yet, a unique subset of HCC fibrolamellar hepatocellular carcinoma (FLHC) is reported only from the United States. Five cases of FLHC from ...

We used data reported to Medicare from 1983 through 1986 to determine the incidence of end-stage renal disease (ESRD) among Native Americans and Whites in the United States. The 1,075 Native American cases represented an annual incidence, age-adjusted to the White population, of 269 per million, 2.8 times the rate ...

"As part of a current concern among geographers to identify the local specificity of labour markets...and the regional impacts of international migration from [the United Kingdom], this paper considers one case of regional specificity--the Port of Liverpool--and how the traditional skills of the port and associated activities, on and off-shore, ...

We present the case of an otherwise healthy woman with noduloulcerative ("malignant") syphilis, the first female patient reported with this dermatosis in fifty years. This rare form of secondary syphilis is characterized by noduloulcerative lesions with rupioid crusts that dramatically involve the face while usually sparing the palms and soles. ...

A 25-year-old man developed classical hydrophobic rabies 3 months after being bitten on the face. We present his involuntary movements on videotape and discuss the clinical and epidemiological features of rabies. Though rabies is seen in tropical countries commonly and in North America occasionally, recording of the clinical features is ...