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Konca Degertekin Ceyla C Department of Endocrinology and Metabolism, Gazi University Faculty of Medicine, Gazi Üniversitesi Hastanesi, 06100 Be┼čevler, Ankara, - - 2014
Polycythemia vera is a clonal proliferative disorder of the bone marrow that could possibly evolve into myelofibrosis in its natural course. Progression to myelofibrosis is usually a late stage complication and presents clinically with refractory cytopenias and extramedullary hematopoiesis (EMH). EMH can occur in any tissue during the course of ...
George Mathew M - - 2012
Reports describing methadone overdose in adult and pediatric patient populations are not uncommon. Reports in the preterm neonate patient population, however, are infrequent even though the utilization of methadone in that population continues to increase. Significant age-related pharmacokinetic differences complicate the management of methadone overdose in neonates, and literature involving ...
Wong Janice C - - 2012
Pallidonigroluysian atrophy is a rare neurodegenerative disease characterized by degeneration of the globus pallidus, substantia nigra, and subthalamic nucleus. Few studies have comprehensively documented the clinical and pathological features of pallidonigroluysian atrophy. A systematic review of all published cases of pallidonigroluysian atrophy in English since 1970 was performed. We also ...
Koma Yasuko - - 2012
Gefitinib and erlotinib, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), are widely used anticancer drugs for patients with non-small cell lung cancer (NSCLC), especially for those with EGFR-activating mutations. Both agents are considered to be less toxic compared with cytotoxic drugs; however, serious adverse events including interstitial lung ...
Haws Bryn - - 2012
We reviewed the data on external histopathology review for patients referred to our institution for sentinel lymph node biopsy (SLNB) associated with melanoma, Merkel cell carcinoma and adnexal carcinoma. We calculated the incidence of external histopathology review and the rate of discordance between internal and external histopathology diagnoses between January ...
Balaban Muhsin - - 2012
Hemangiopericytoma, which is derived from pericytes, is rarely seen in the kidney and adical nephrectomy with or without chemotherapy is the treatment of choice in most of the cases. We report a fifty-year-old male patient presenting with gross hematuria that radiologic evaluation confirmed due to a solid mass in the ...
Kikumoto Y - - 2012
Fabry disease (FD) is an Xlinked disorder resulting in a deficiency in α-galactosidase A (α-Gal) activity. FD is one of the causes of progressive renal dysfunction, but its diagnosis is often delayed or missed completely. We herein report the case of a 70-year-old male who had been receiving hemodialysis (HD) ...
Hu Honglin - - 2012
Context:We report on a case of adrenal angiomyolipoma.Objective:The aim was to present a case report and review of the literature about adrenal angiomyolipoma.Design:The case report includes a history of patient data and literature review.Setting:The patient was offered adrenalectomy with adrenal gland neoplasms and gave consent. The tumor was completely removed.Patient:We ...
Zhou Yu - - 2012
OBJECTIVE: Rhabdoid meningioma (RMs) is a rare sub-type of meningiomas, classified as WHO grade III with poor prognosis. Here we present our experience on RMs and reviewed relevant literatures in an attempt to investigate the clinical features, treatment and prognosis of these tumors. METHODS: 12 patients underwent surgical treatment for ...
Polci Rosaria - - 2012
A case of granulomatous interstitial nephritis (GIN) associated with Crohn's disease (CD) was reported. GIN is a rare pathological finding in renal biopsy specimens. In a patient affected by CD, granulomas may be found in various tissues and organs such as lymph nodes, mesentery, liver, and lungs and occasionally in ...
Vinchon Matthieu - - 2012
Sagittal craniosynostosis (SCS) is common and easily recognized and corrected surgically. However, rare cases of SCS are more complex: these associate closure of the metopic or delayed closure of the coronal suture, uni- or bilaterally. We reviewed the available literature on atypical sagittal craniosynostosis (ASCS). We also reviewed retrospectively our ...
Martín-Fuentes Ana María - - 2012
Neurofibromatosis (NF) type 1 is characterized by several skin, endocrine, central nervous system and musculoskeletal manifestations, spine deformities being the most common, affecting up to 64% of patients. Thoracic kyphoscoliosis is the most common deformity observed; however, high-grade spondylolisthesis and dural defects such as dural ectasia can also be found. ...
Wick Jane M - - 2012
Early-onset scoliosis presents at birth and up to five years of age. Growing rods are a treatment option when early-onset scoliosis cannot be controlled by serial casts or braces. The function of a growing rod is to allow a child's spine to continue to grow under controlled conditions until a ...
Furr Joe C - - 2012
Sepsis and respiratory failure are uncommon complications of infection with H1N1 influenza. In the majority of cases of H1N1-associated sepsis and respiratory failure found in the literature, evidence of pneumonia or the acute respiratory distress syndrome was seen on chest radiography. This case report describes the clinical characteristics of a ...
Davis James S - - 2012
Segmental absence of the intestinal musculature (SAIM) is a known but clinically rare entity involving partial or complete absence of the intestinal muscularis propria. Clinical presentation is consistent with peritonitis, and treatment involves an emergent laparotomy, bowel resection, and reanastamosis or possible ostomy creation. Diagnosis results from histopathologic evaluation of ...
Anderson J L - - 2012
BACKGROUND: The intestinal microbiota is involved in the pathogenesis of inflammatory bowel disease (IBD). Faecal microbiota transplantation (FMT) has been used for the management of IBD as well as infectious diarrhoea. AIM: To undertake a systematic review of FMT in patients with IBD. METHODS: The systematic review followed Cochrane and ...
Hernández-Martín Angela - - 2012
BACKGROUND: Eosinophilic pustular folliculitis (EPF) of infancy is characterized by the presence of pustular lesions containing eosinophils. It is the least well-characterized of the EPF diseases. OBJECTIVES: We sought to define the clinical and histopathologic features of the condition. METHODS: We conducted a retrospective review of the clinical data and ...
Penders Thomas M - - 2012
In published reports of hallucinatory delirium following use of "bath salts" analytic laboratory testing has demonstrated the synthetic cathinone derivative methylenedioxypyrovalerone (MDPV). MDPV can cause a false-positive screening immunoassay result for phencyclidine (PCP). Patients using MDPV are prone to development of the syndrome of excited delirium (ExD), a condition also ...
Swapp Ryan E - - 2012
Context.-Original surgical pathology materials from external sources are reviewed by our pathologists for referred patients before their clinical evaluation and treatment. Objective.-To identify the rate of major disagreements with diagnoses from external institutions and to characterize the nature and impact of discordant diagnoses on patient care. Design.-We identified and reviewed ...
Antinori Spinello - - 2012
OBJECTIVES: The aim of this study was to highlight the increasing chance of Western physicians encountering patients (both immigrants and expatriates/travelers) seeking help for loiasis. METHODS: We describe three cases of imported loiasis observed at two hospitals in Italy and France, and present a review of all previously published cases ...
Irwin Richard Bruce RB Cardiovacular Division, Department of Cardiology, North West Heart Centre, University Hospital of South Manchester, Southmoor Road, Manchester M23 9LT, UK. - - 2013
Cardiac magnetic resonance (CMR) imaging benefits from a large field of view, but consequently captures incidental extra-cardiac findings (IEFs). There is a relative paucity of data for CMR in this regard. Our objectives were to assess the frequency and significance of IEFs reported from clinically indicated CMR scans, and additionally ...
Zaraa Inès - - 2012
Inflammatory Tinea capitis (TC) is a rare form of TC. The aim of this study was to review epidemiological, clinical and mycological profile of inflammatory TC. We present a retrospective study (1999-2010), enrolled all the cases of inflammatory TC observed at a referral hospital in the northern Tunisia. One hundred ...
Hassadia Ayman - - 2012
To highlight the clinical presentation, treatment, histological review and outcome of patients referred to the Sheffield Centre with possible ectopic gestational trophoblastic disease (GTD). A retrospective case note review of patients with possible ectopic GTD referred to the Sheffield Centre between 1997 and 2010 was performed. During the 13 years ...
Linnell Joshua D - - 2012
Ultraviolet (UV) dyes are used as inks in garment printing. Hypersensitivity reactions to these compounds have been reported in the literature. The authors report a case of reaction to UV ink in a patient already on corticosteroid therapy. The patient's clinical course was reviewed along with images of wounds that ...
Masood Syed Asif - - 2012
The haematologic disorder b-thalassemia major is common in Pakistan. We describe a patient with undiagnosed thalassemia presenting with hypertension and convulsions and found to have cerebral haemorrhage on neuro-imaging. He had been transfused 2 weeks before this illness. Our experience is similar to a few case reports described in literature ...
Komeya Mitsuru - - 2012
A 70-year-old man presented with a left scrotal swelling. A computed tomography scan showed an 8-cm left scrotal mass and no metastasis. Radical orchiectomy with high ligation of the spermatic cord was performed. The tumor was classified as a high-grade leiomyosarcoma of the left testis. An intensive follow-up including repeated ...
Patel Sandeep M - - 2012
Pulmonary alveolar proteinosis (PAP) is a disease of alveolar accumulation of phospholipoproteinaceous material that results in gas exchange impairment leading to dyspnea and alveolar infiltrates. There are three forms of PAP: congenital, acquired and idiopathic; of which the latter two are predominant in the adult population. Previous case studies have ...
Hernández-Bel P - - 2012
Syphilitic alopecia occurs in only 4% of patients with syphilis. We present 5 cases of this uncommon manifestation and review the corresponding literature. All of the patients in our series were men aged between 31 and 46 years. The lesions, which were located mainly in the parieto-occipital area of the ...
Albuquerque Andreia - - 2012
We report a case of a cirrhotic patient who developed a spontaneous bacterial empyema due to Clostridium perfringens. To our knowledge, only two cases of spontaneous bacterial empyema due to C. perfringens in cirrhotic patients were previously reported in literature. It should be suspected in a Child C cirrhotic patient, ...
Maillet Jean Michel - - 2012
Infectious aortitis has become a rare disease thanks to the widespread use of antibiotics. We report the case of a patient who, 15 days after initiation of antibiotics for bacteraemia due to methicillin-resistant Staphylococcus aureus (MRSA), developed acute chest pain followed by haemodynamic instability. A tamponade due to a rupture ...
Duggan Joan - - 2012
AIDS-related cryptococcal meningitis can result in significant vision loss, but the risk factors, prognostic features, and optimal management of patients with ocular complications is unknown. We present 2 cases of blindness associated with cryptococcal meningitis and review the literature for associated cases. Twenty-six additional cases of vision deterioration or loss ...
Liang Conan - - 2012
Abstract Extramedullary acute megakaryoblastic leukemia (AMKL) is a rare neoplasm with complex clinical presentations and is frequently confused with other small blue cell tumors (SBCT) in pediatric patients. Primary mastoid manifestation of AMKL has never been reported. The extreme rarity of mastoid AMKL combined with the tendency of extramedullary AMKL ...
Castro José Guillermo - - 2012
The purpose of the study was to evaluate the clinic prevalence and clinical characteristics of patients with LGV since 2007 when active clinic surveillance started. We review all the reports of rectal Chlamydia trachomatis and LGV testing of those samples. Chlamydia trachomatis LGV DNA was detected by Nucleic Acid Amplification/ompA ...
Bhole M V - - 2012
Local anaesthetic (LA) agents have been routinely used in dentistry, ophthalmology, minor surgery, and obstetrics since the late nineteenth century. Reports relating to adverse reactions and LA allergy have appeared in the published literature for several years. However, the incidence of true, IgE-mediated LA allergy remains uncertain and is presumed ...
Mushtaque Majid - - 2012
A biloma is an encapsulated bile collection outside the biliary tree. Most cases are caused mainly by iatrogenic injury and trauma, and are usually located in the sub-hepatic space. Spontaneous biloma is an uncommon entity. We report three rare cases of spontaneous hepatic subcapsular biloma formation in association with choledocholithiasis ...
Ranger Adrianna M - - 2012
This study aimed to identify the causes and contributing factors, neurologic presentation, and outcomes of central pontine and extrapontine myelinolysis and to examine any trends in the presentation and course of these disorders over the past 50 years. Seventy-six pediatric cases were identified in the literature. Age, sex, decade of ...
Nash R - - 2012
Background:Spontaneous pneumocephalus is a rare condition that has been reported infrequently. Alien limb syndrome is an uncommon phenomenon most often seen in patients with frontal and callosal lesions.Method:Case report of a patient with pneumocephalus presenting with alien limb syndrome. The patient underwent successful surgical management. A literature review and discussion ...
Omair Mohammed A - - 2012
Tumor necrosis factor inhibitors (TNFI) are novel therapies used to treat ankylosing spondylitis (AS). Demyelinating disease is a rare but serious complication of TNFI. We report a patient with a case of AS who developed demyelinating disease secondary to TNFI and was treated successfully with rituximab.
Bando Hideki - - 2012
OBJECTIVES/HYPOTHESIS: We report the first case of laryngeal stenosis with granuloma in a patient with severe congenital neutropenia (SCN). STUDY DESIGN: Case report and retrospective review. METHODS: Review of medical records. RESULTS: A 6-year-old female who was diagnosed with SCN presented with a cough and wheezing. An endoscopic study revealed ...
Abreu Cândida - - 2012
Listeria monocytogenes is an aerobic gram positive intracellular bacillus, predominantly affecting pregnant women, immunocompromised patients and old individuals. Invasive listeriosis, meningitis and meningoencephalitis, bacteraemia with or without joint, eye or heart focalization are clinical manifestations of the disease. Anti-TNF-α drugs blocking the host's response against various microorganisms, particularly intracellular agents ...
Gooskens S L M - - 2012
Clear cell sarcoma of the kidney (CCSK) is a rare renal tumour that is observed most often in children under 3years of age. Only a few large series of CCSK have been reported and patients with CCSK are often included among patients with other types of childhood renal tumours. The ...
Spiliopoulou Anastasia - - 2012
Rhodotorula species are commensal yeasts that have emerged as a cause of life-threatening fungemia in severely immunocompromised patients. A case of Rhodotorula mucilaginosa fungemia in a 48-year-old woman that had undergone consecutive abdominal surgeries due to ovarian cancer and bowel necrosis while she was receiving fluconazole prophylaxis is presented. Several ...
Guleri Achyut - - 2012
Abstract Background: Anaphylactic reactions to chlorhexidine are rare but are being reported increasingly in association with a variety of products. Methods: We report three cases of anaphylaxis to chlorhexidine in patients presenting for cardiac surgery. Results: In each case, anaphylaxis was precipitated by the insertion of a central venous catheter ...
Livovsky Dan M DM - - 2012
Bordetella holmesii is a slow-growing, gram-negative, non-oxidizing, brown soluble pigment-producing bacillus, originally described by Wayant et al. as CDC nonoxidizer group 2 (NO-2) (Weyant et al., 1995). It has recently been shown that B. holmesii may be isolated from nasopharyngeal specimens of up to 20% of patients with pertussis-like symptoms ...
Abdelrahman M Z - - 2012
INTRODUCTION: Strongyloides stercoralis infection can persist in the host for several decades, and patients with cancer and other clinical conditions who are exposed to immunosuppressive therapy are at risk of developing hyperinfection. CASE REPORT: This is a case of angioimmunoblastic T-cell lymphoma (AITL) in a patient with lymphadenopathy and bulky ...
Wang Chenglin C Department of Medical Imaging, Peking University Shenzhen Hospital, Shenzhen, - - 2012
This article is about 3 cases of accessory lobes of the liver. Case One involved a pedunculated accessory lobe of the liver (ALL), Case Two involved a true ectopic liver, and Case Three involved a sessile accessory lobe of the liver. All 3 cases were diagnosed by computed tomography (CT) ...
Goyal Tarun - - 2012
Involvement of upper cervical and craniovertebral junction is rare but might lead to lethal consequences if the diagnosis is delayed. We present a case of atlantoaxial joint tuberculosis, resulting in gross instability of the joint. The patient was treated with antitubercular medication combined with posterior decompression and transarticular screw fixation. ...
Zadroga Rebecca J - - 2012
Streptococcus pneumoniae is an uncommon cause of pyomyositis. It is unclear if the clinical presentation and outcome of pneumococcal pyomyositis differ depending on underlying host immune status. We report 2 patients with pneumococcal pyomyositis, review all published cases and compare patient characteristics in apparently normal and at-risk hosts.A total of ...
Ud Din Nasir - - 2012
AimsTo report the exceedingly rare occurrence of oligodendroglioma in the glial component of ovarian teratomas.MethodsSix cases of oligodendrogliomas arising in the glial component of ovarian teratomas were studied and the literature was reviewed. Immunohistochemistry was performed by the Flex technique.ResultsThe ages of the patients ranged from 12 to 28 years ...
Gómez-Laencina Ana M - - 2012
Neurofibromatosis within the female genital tract is uncommon. The vulva is the most frequent genital location, but it has rarely been reported in the context of the vagina, uterine cervix or ovaries. In spite of its rarity, neurofibroma is a neoplasm that should be considered in the differential diagnosis of ...
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