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Abdulla Farah Rukhsana - - 2010
BACKGROUND: Amelanotic lentigo maligna is not clinically suspected and is often mistaken for a basal cell carcinoma, squamous cell carcinoma, or dermatitis. OBJECTIVE: Our objective was to review previously reported cases of amelanotic lentigo maligna and compare them with our 3 cases. METHODS: The clinical presentation and histologic findings of ...
Fine Jo-David - - 2009
It is well known, primarily via case reports and limited case series, that nonepithelial tissues may become injured in patients with epidermolysis bullosa. Only recently, however, have there been data generated from large, well characterized cohorts. Our objective is to provide dermatologists with a comprehensive review of each of these ...
Park Sung Hye - - 2009
Primary ovarian choriocarcinoma arising from a germ cell is an extremely rare occurrence, especially in postmenopausal women, and the prognosis is poor. Non-gestational choriocarcinoma of the ovary (NGCO) accounts for 0.6% or less of all ovarian neoplasms. It is important to distinguish gestational choriocarcinomas of the ovary (GCO) from other ...
Sirikanjanapong Sasis - - 2010
Merkel cell carcinoma (MCC), a rare aggressive primary cutaneous neuroendocrine carcinoma, occurs on sun-damaged skin, especially in the elderly. Its unique co-expression of cytokeratin 20 (CK20) and neuroendocrine markers, including neuron-specific enolase (NSE), is diagnostic. Most MCCs are located in the dermis, rarely has an intraepidermal component been reported. We ...
Yiotakis J - - 2009
INTRODUCTION: Verrucous carcinoma is a variant of well differentiated squamous cell carcinoma characterised by an exophytic, warty growth which is slowly but locally invasive and which can cause extensive local destruction if left untreated. CASE REPORT: We report the first known case of veruccous carcinoma of the paranasal sinuses with ...
Gupta Narmada P - - 2010
We describe a very rare congenital anomaly of the inferior vena cava in a case who presented with renal calculi and transitional cell carcinoma on the right side. The diagnosis of 'periureteric venous ring' was made on preoperative imaging and confirmed on surgical exploration. We also review the literature and ...
Bellew Susun - - 2009
Primary carcinosarcoma is a very rare neoplasm comprising two intermingling malignant components-epithelial and mesenchymal. The authors report a new case of primary cutaneous carcinosarcoma involving the helix of the ear. Immunohistochemical analysis revealed epithelial components of both basal cell and squamous cell carcinomas with a partially ossified sarcomatous-like component.Cutaneous carcinosarcoma ...
Hedgepeth Ryan C - - 2009
We report the case of a 5-year-old girl with metastatic renal cell carcinoma (RCC) diagnosed 19 months after treatment for neuroblastoma. Immunostaining of the secondary tumor was consistent with Xp11 translocation morphology. This is the second report of this translocation RCC presenting after neuroblastoma and the most rapid onset of ...
Bahig H - - 2009
Small cell carcinomas of the endometrium are rare and carry an ominous prognosis. Most patients present with advanced disease. The histopathological diagnosis requires immunohistochemistry confirmation and the tumor should be positive for a neuroendocrine marker. This article reports a new case and reviews the pertinent literature on the subject.
Sidell Douglas - - 2009
OBJECTIVES/HYPOTHESIS: Describe a rare pediatric malignancy. Discuss the clinical, diagnostic, and therapeutic differences between squamous cell carcinoma (SCC) of the adult and pediatric population. STUDY DESIGN: Case report including a detailed radiological and histopathologic analysis and review of the literature. METHODS: A case report is described from a tertiary care ...
George A - - 2010
OBJECTIVE: We report the first documented case in the world literature of primary extra-pulmonary small cell carcinoma occurring in the neopharynx following laryngectomy. METHOD: We present a case report and a review of the world literature regarding the management of tumours of the neopharynx and extra-pulmonary small cell carcinoma. RESULTS: ...
Chang H - - 2010
Hepatocellular carcinoma (HCC) presenting with obstructive jaundice due to bile duct tumour thrombi is classified as icteric-type hepatoma. This report describes a case of unusual icteric-type HCC with common bile duct thrombus, which is herein named 'occult HCC', as no detectable primary lesion in liver was defined pre-operatively and intra-operatively. ...
Lin Harrison W - - 2010
OBJECTIVE: The objective is to present an uncommon case of squamous cell carcinoma (SCC) arising from extensive recurrent respiratory papillomatosis (RRP) involving the upper and lower airway and temporal bone. STUDY DESIGN: This is a case report and a review of the literature. METHODS: We describe a case of a ...
Toll Adam D - - 2011
Acinar cell carcinoma of the pancreas is rare, accounting for less than 1% of carcinomas arising in the exocrine pancreas. Patients are typically between the fifth and seventh decade of life and show a 2:1 male predominance. Symptoms tend to be nonspecific, and approximately 50% of the patients have metastases ...
Sileri Pierpaolo - - 2009
Metastatic lesions of the spleen are a rare finding and are generally associated with widespread disease. Moreover, solitary metastases of the spleen are exceptional. In this paper, we describe the case of a patient who developed an isolated splenic metastasis from colon carcinoma five years after surgery, and was successfully ...
Ruan Joseph H - - 2009
Merkel cell carcinoma is a rare and aggressive malignancy of the skin. Approximately 2000 cases of Merkel cell carcinoma have been reported since its first published description in 1972. Owing to its rarity, scientific studies have been difficult. Our current knowledge is based on retrospective case studies and case reports. ...
Chappell Jeaneen A - - 2009
Sorafenib, a multitargeted kinase inhibitor used for the treatment of unresectable hepatocellular carcinoma and advanced renal cell carcinomas, received FDA approval in 2005. Since its introduction to the market, there have been various dermatologic side effects reported in the literature, the most well known being hand-foot skin reaction. This article ...
Haddad Jamie L - - 2009
Squamous cell carcinoma (SCC) is a neoplastic proliferation of epithelial cells undergoing squamous differentiation and represents a diagnostic challenge in non-human primates (NHP), especially in baboons with perineal SCC. Fourteen SCC (13 baboons, 1 spider monkey) were identified over a 20-year period. A literature search identified 86 additional published cases ...
Kulahci Y - - 2009
OBJECTIVE: We report an extremely rare case of distant metastasis to the rectus femoris muscle from a laryngeal squamous cell carcinoma. METHOD: We present a case report and a review of the world literature concerning distant skeletal muscle metastasis from head and neck squamous cell carcinoma. RESULTS: The patient showed ...
Ramos Lara Maria A - - 2009
Keratoacanthoma (KA) is a self-limited benign epithelial proliferative lesion that eventually presents with very similar clinical features to squamous cell carcinoma. Many KA appear in the vermilion border of the lips and therefore dental professionals must be familiar of the disease. This article reports the case of a 40-year-old female ...
Garcia Jorge A - - 2009
PURPOSE OF REVIEW: This review is intended to provide information on recent advancements in renal cell carcinoma (RCC) treatments as well as give insight on present-day clinical and molecularly based biomarker studies. RECENT FINDINGS: A review of recent literature regarding RCC epidemiology and clinical prognostic factors will be provided. Information ...
Wilkins Benjamin J - - 2009
Parathyroid carcinoma is a rare malignancy, and only accounts for 0.5-2% of cases of primary hyperparathyroidism. Less than 10% of parathyroid carcinomas are non-functional, and as such, they have been rarely reported in the literature. Importantly, margin status at resection is related to prognosis, and only a handful of case ...
Okudela Koji - - 2010
We present a case of a polypoid tumor located in the right middle lobe bronchus. The tumor was composed of bi-layered glandular or ductular structures consisting of inner cuboidal cells and outer multipolar cells. Immunohistochemical examinations confirmed epithelial and myoepithelial differentiation in the inner and outer components, respectively. Consequently, the ...
Coli Antonella - - 2010
Reports about adrenocortical carcinomas (AC) mixed with sarcomatous areas are very rare. The terminology and pathogenesis of such biphasic tumors remain controversial. Herein, we report a case of sarcomatoid carcinoma of the adrenal gland in a 75-year-old woman who presented with left abdominal pain of one month's standing. The results ...
Iype S - - 2009
Primary neuroendocrine tumours (NETs) of the gallbladder are rare. In the absence of any randomised controlled trials or prospective case series, we sought trends for clinical presentation and management based on 60 patients from published literature over the last 15 years, as well as three patients from our experience, and ...
Mayer W A - - 2009
Synchronous metastasis of renal cell carcinoma (RCC) to the ureter or the bladder represents an extremely rare event. We report one case of synchronous metastasis of RCC to the ipsilateral ureter and one case of solitary synchronous metastasis of RCC to the urinary bladder. We review the literature and discuss ...
Fraga Garth R - - 2010
Background: Keratoacanthoma is interpreted by many dermatopathologists in the United States as a form of squamous cell carcinoma that can spontaneously involute. Rare examples arising in tattoos have been reported in the literature. Materials and methods: We retrospectively reviewed all cases from our institution received between 2000 and 2008 for ...
Alsharif Mohd Jamal - - 2009
Squamous cell carcinoma is a malignant neoplasm of epithelium, most frequently occurring in intraoral tumors. In this article we describe a rarely reported, because the frequency of oral cancer in young people is extremely low, case of a 16-year-old Chinese girl with squamous cell carcinoma of anterior mandibular gingiva. The ...
Ajibode H A - - 2009
AIM: To review the current literature on squamous cell carcinoma [SCC] of the conjunctiva and report 2 presentations in Sagamu, Nigeria since the availability of histopathological services. METHODS: The available literature using e-medicine and pubmed internet websites were summarized. The 2 cases seen by the first author since histopathological services ...
Xu Gang - - 2009
Renal small cell carcinoma is a rarely seen malignant neoplasm with high propensity for distant metastasis and aggressive behaviour showing combined characteristics of neuroendocrine and epithelial neoplasia in terms of immunohistochemistry and ultrastructure. To the best of our knowledge this is the first report of primary small cell carcinoma of ...
Sabri Alain - - 2009
Leishmaniasis of the auricle has been rarely reported in our region of the world, where it is labeled as "Old World Leishmaniasis." It may mimic other pathologies, such as malignancies or other infectious processes. We present a case of an auricular Leishmania lesion which was first suspected to be a ...
Rogers Heather D - - 2009
Epidermodysplasia verruciformis (EV) is a rare autosomal recessive genodermatosis with an increased susceptibility to specific human papillomavirus (HPV) genotypes. Classically, this viral infection leads to the development of tinea versicolor-like macules on the trunk, neck, arms, and face during childhood, and over time, these lesions can progress to squamous cell ...
Katz Ryan D - - 2009
This is a report of a patient with squamous cell carcinoma discovered in a bed of longstanding (>20 years) hidradenitis suppurativa. A literature search demonstrates this to be an entity with potentially devastating sequelae if not expediently diagnosed and treated. In light of the possibility of malignant transformation, the hidradenitis ...
Woo Victoria L - - 2009
Squamous cell carcinoma (SCC) is a rare finding in the adolescent population, with most cases occurring in patients with underlying heritable diseases or immunologic conditions. Moreover, the incidence of oral SCC in this age group is extremely low. While isolated cases of adolescent oral SCC have been documented, most have ...
Chadrawar Shivani - - 2009
In this case report we present an unusual appearance of myocardial uptake of Tc-99m HDP in a 59-year-old renal transplant patient who was imaged while looking for metastases from adenocarcinoma of the prostate. Subsequent investigation demonstrated no obvious cause for this appearance, such as myocardial disease or metastatic cancer. The ...
Trivedi Priti - - 2009
Hepatocellular carcinoma rarely metastasizes to skull base. We report an extremely rare case of solitary skull base metastasis without metastasis to any other site, with right third, fourth, and sixth cranial nerve palsy as the initial manifestation of the disease. The biopsy specimen of skull base lytic lesion suggested metastatic ...
Okamoto Norihiro - - 2009
Metachronous multiple carcinomas at the site of a stoma is a rare condition after surgery. A 67-year-old man with a second tumor at the stoma site 15 years after abdominoperineal resection for rectal carcinoma is reported herein with a review of the Japanese literature. The patient visited our hospital 20 ...
Thomakos Nikolaos - - 2009
Choroidal metastases from gynaecological primary are extremely rare. There is no documented case in the literature of choroid metastasis in a patient with primary peritoneal carcinoma (PPC). We describe the first case of a 54-year-old woman with a history of borderline mucinous tumour who presented 17 months later with PPC ...
McKenzie Bruce J - - 2009
Axillary nodal metastasis is very rare in head and neck squamous cell carcinoma. The few cases reported in the literature all involve patients who have previously undergone either neck dissection alone, or neck dissection and radiotherapy to the neck, and subsequently develop delayed recurrences of disease, with axillary nodal involvement. ...
Kyriazi Maria A - - 2009
INTRODUCTION: Pancreatic tumors usually display either a ductal, an acinar or an endocrine differentiation. Mixed exocrine and endocrine pancreatic tumors are extremely rare. There have been a few reports of the rare entity of mixed acinar-endocrine carcinoma of the pancreas, where the endocrine cells represent more than 30% of the ...
Li M - - 2009
The sign of Leser-Trélat (LT) is defined as the sudden eruption of multiple seborrhoeic keratoses (SKs), or increase in the number and size of existing SKs, associated with an underlying malignancy. A 75-year-old man was admitted to our hospital with dyspnoea and multiple verrucous papules that had been developing gradually ...
Pinchot Scott N - - 2009
Pituitary carcinomas are rare neuroendocrine tumors affecting the adenohypophysis. The hallmark of these lesions is the demonstration of distant metastatic spread. To date, few well-documented cases have been reported in the literature. Here, we report the case of a fatal pituitary carcinoma evolving within two years from an adrenocorticotrophic hormone ...
Efron Philip A - - 2008
Basal cell carcinoma (BCC) is a rare disease in the pediatric population that usually presents in children with predisposing genetic conditions. It is often diagnosed on final pathology of an excisional biopsy, and the treatment may be delayed in younger populations because of a physician's low index of suspicion. Increased ...
Kapoor Anil - - 2008
Renal cell carcinoma (RCC) with rhabdoid features is an uncommon and highly aggressive malignancy. We report a case of adult clear-cell RCC with extensive rhabdoid features treated with the tyrosine kinase inhibitor sorafenib. A review of the literature summarizes important aspects of this malignancy. We discuss clinical and histological findings ...
Joos Beth - - 2009
Squamous cell carcinoma (SCC) of the larynx is extremely rare in adolescents and typically has an aggressive nature. The mechanism of laryngeal oncogenesis is complex and little is known about the role that human papillomavirus (HPV) plays in SCC in adolescents. We report a case of invasive laryngeal SCC that ...
Autelitano L - - 2009
Pilomatrix carcinoma, the malignant equivalent of pilomatrixoma, is rare among skin cancers. In the literature, there have been 80 cases of pilomatrix carcinoma reported, and among them nine were with metastases. The clinical presentation of this case is suggestive for the biology and of the usual history of this neoplasm. ...
Duprat J P - - 2009
INTRODUCTION: Merkel cell carcinoma (MCC) is a very rare and aggressive neoplasm. Due to its rarity, therapeutic guidelines are not well established, especially for regionally advanced disease. Hyperthermic isolated limb perfusion (HILP) with Melphalan and either with or without tumor necrosis factor-alpha (TNF-alpha) is becoming more common in clinical practice, ...
Draganova-Tacheva Rossitza Anguelova - - 2009
Large cell neuroendocrine carcinoma (LCNEC) of the ovary is a rare entity and is frequently associated with ovarian surface epithelial tumors. However, its association with serous carcinoma has only been described recently in one case. We report another case of such with mucin production in a 68-year old woman. Immunohistochemistry ...
Altaykan Asli - - 2008
Nevus sebaceous usually occurs as a solitary lesion located mostly on the scalp and the face. The potential for nevus sebaceous to develop malignancy is well recognized, though it is generally thought that this transformation occurs only postpubertally or later. However, few cases of basal cell carcinoma arising in nevus ...
DeAmbrosis Kathryn - - 2008
Four cases of vulval basal cell carcinoma were identified in multiparous females aged 46-78 years. Symptoms included discomfort and pruritus ranging from 6 weeks to 4 years in duration. Such symptoms occurred in the context of a pink vulval plaque. The non-specific symptoms, in the context of the particular anatomical ...
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