Search Results
Results 201 - 250 of 928
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Newman Simon D S SD Imperial College London, Level 7 East Wing, Charing Cross Hospital, Fulham Palace Road, London, W6 8RF, UK. - - 2013
The Ligament Augmentation and Reconstruction System (LARS) is a third generation of synthetic ligament, designed to overcome the issues of graft failure and synovitis which led previous generations of synthetic ligaments to fall out of favour. The theoretical benefits of LARS are appealing but this has not led to widespread ...
Hartling Lisa - - 2012
OBJECTIVES: To assess the reliability of the Cochrane Risk of Bias (ROB) tool between individual raters and across consensus agreements of pairs of reviewers and examine the impact of study-level factors on reliability. STUDY DESIGN AND SETTING: Two reviewers assessed risk of bias for 154 randomized controlled trials (RCTs). For ...
Wiffen Philip J - - 2012
ABSTRACT The Cochrane Library of Systematic Reviews is published quarterly as a DVD but monthly online. The April 2012 issue (second DVD for 2012) contains 5045 complete reviews, 2182 protocols for reviews in production, and 17,084 short summaries of systematic reviews published in the general medical literature. In addition, there ...
Yusuf Syed Wamique - - 2012
Endocarditis and myocarditis are conditions seen worldwide with considerable morbidity and mortality. Despite the improvements in diagnostic technologies, clinical diagnosis remains crucial as only prompt recognition will lead to appropriate investigations and timely intervention, which may be life saving. In this review, the authors provide a concise overview of endocarditis ...
Jhamb Aakarsh - - 2012
Fibrous dysplasia can present clinically in varied forms which may appear as collision of different pathologic processes. We report a rare case of craniofacial fibrous dysplasia with coexisting epithelial lined cyst and superimposed osteomyelitis with sequestrum formation. Its clinical features and management with possible hypotheses are described along with the ...
Jean Sherrie M - - 2012
Over a 5-y period, 3 chimpanzees at our institution experienced cerebrovascular accidents (strokes). In light of the increasing population of aged captive chimpanzees and lack of literature documenting the prevalence and effectiveness of various treatments for stroke in chimpanzees, we performed a retrospective review of the medical records and necropsy ...
Littlewood Chris - - 2012
The systematic review has become an increasingly popular method of synthesizing findings on a topic in order to inform clinical practice, commissioning of care, and future research. A central component of the systematic review is an assessment of study quality or risk of bias, i.e. an assessment of how near ...
Ha Kee-Yong - - 2012
Metastatic spine disease (MSD) is a complex disease entity requiring multi-discipline and multi-modality approach to obtain the most reasonable clinical outcomes. As one of these trials, radiofrequency ablation (RFA) has been tried. Here, we describe four cases of metastatic spine lesions (2 hepatomas, 1 lung cancer, 1 breast cancer) that ...
Sugarman Alan - - 2012
Despite a growing body of clinical literature advocating the thoughtful and judicious use of self-disclosure in psychoanalysis, there remains a reflexive reluctance to intervene in this way by many analysts of various theoretical persuasions. Why is this the case? Four motives for this reflexive reluctance to self-disclose are discussed: (1) ...
Kumar Mani Kant - - 2012
Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare neurodegenerative disease seen mainly in the Aggarwal community in India. It is characterized by early-onset macrocephaly with mild motor developmental delay, gradual onset ataxia, spasticity, seizures and usually late onset mild cognitive deterioration. Very few familial cases of MLC have been ...
Lobb Ryan - - 2012
The aim of this systematic review of systematic reviews was to critically appraise systematic reviews on Anterior Cruciate Ligament (ACL) reconstruction rehabilitation to determine which interventions are supported by the highest quality evidence. Electronic searches were undertaken, of MEDLINE, AMED, EMBASE, EBM reviews, PEDro, Scopus, and Web of Science to ...
Oomens Marjolijn A E - - 2012
Controversy exists about the efficacy of antibiotic prophylaxis in preventing complications after lower third molar surgery. For evidence-based recommendation, a review was performed on clinical trials reporting the use of antibiotic prophylaxis compared with no treatment or placebo with "infection" as outcome. Useful studies were identified using Embase, Cochrane, and ...
Pillai Gopal S - - 2012
Intraocular gnathostomiasis is a rare parasitic infection caused by the third-stage larvae of spiruroid nematode Gnanthostoma spp. seen mostly in tropical and subtropical regions. It is a food-borne zoonosis caused by ingestion of raw or undercooked freshwater fish, amphibians, reptiles, birds, and mammals, all of which are known to harbor ...
Kumar Sumir - - 2012
The Bardet-Biedl syndrome (BBS) is a rare ciliopathic human autosomal-recessive disorder, affecting multiple organ systems. Less than 15 cases have been reported from India. The authors present a classical case of BBS presenting to dermatology outpatient with hypogonadism and features such as marked central obesity, retinal dystrophy, polydactyly, structural renal ...
Senthilkumaran Subramanian - - 2012
We report a case of gas gangrene (GG) in a non-diabetic HIV seronegative man who died within 60 hours following an intramuscular injection in rural India. The occurrence of GG after intramuscular injection is rare and only a few cases have been reported in the published literature.
Poetker David M - - 2012
BACKGROUND: Corticosteroids are a mainstay of treatment in the management of sinonasal inflammatory disease. Despite their common use, many practitioners are not well versed in their potential complications or the medico-legal ramifications of their use. The objectives of this review were to outline the existing data of the medico-legal implications ...
Seyler Thomas - - 2012
In 2006, several southern states in India reported outbreaks of chikungunya. In the metropolis of Chennai, the first laboratory-confirmed chikungunya cases had an onset of symptoms at the end of May 2006. The authors reviewed surveillance data in which a suspected case of chikungunya was defined as a patient presenting ...
Meerpohl Joerg J - - 2012
[This corrects the article on p. e35732 in vol. 7.].
Alshurafa Mohamad - - 2012
Authors of randomized trial reports seem to hold a variety of views regarding the relationship between missing outcome data (MOD) and intention to treat (ITT). The objectives of this study were to systematically investigate how authors of methodology articles define ITT in the presence of MOD, how they recommend handling ...
Kongsted Hans Christian - - 2012
Increasing the scope of an evidence based approach to areas outside healthcare has renewed the importance of a long-standing discussion on randomised versus observational study designs in evaluating the effectiveness of interventions. We investigate statistically if an increasing recognition of the role of certain nonrandomised studies to support or generalize ...
Houry Debra - - 2012
Prior efforts to train medical journal peer reviewers have not improved subsequent review quality, although such interventions were general and brief. We hypothesized that a manuscript-specific and more extended intervention pairing new reviewers with high-quality senior reviewers as mentors would improve subsequent review quality. Over a four-year period we randomly ...
Schiller Petra - - 2012
Non-inferiority and equivalence trials require tailored methodology and therefore adequate conduct and reporting is an ambitious task. The aim of our review was to assess whether the criteria recommended by the CONSORT extension were followed. We searched the Medline database and the Cochrane Central Register for reports of randomised non-inferiority ...
Rubin Mark N - - 2012
Background: The use of two-way audio-visual technology for delivery of acute stroke is supported by a well established literature base. The use of telemedicine for general neurologic consultation has been reported across most subspecialties within the field, but a comprehensive systematic review of these reports is lacking. Purpose: To conduct ...
Turner Lucy L Ottawa Hospital Research Institute, Ottawa, Canada. - - 2012
An overwhelming body of evidence stating that the completeness of reporting of randomised controlled trials (RCTs) is not optimal has accrued over time. In the mid-1990s, in response to these concerns, an international group of clinical trialists, statisticians, epidemiologists, and biomedical journal editors developed the CONsolidated Standards Of Reporting Trials ...
Faillace César - - 2011
Demyelinating diseases were described in patients receiving anti-TNF agents. Optic neuritis (ON) induced by TNF blockers was already described in 22 cases in the literature. In this article, the authors report a 53-year-old woman with refractory rheumatoid arthritis that developed neuritis optica after the fourth dose of infliximab and had ...
Sun Yong-Xu - - 2011
Anemone raddeana, usually called as'"Toujian Liang" in China, is an Anemone herb belonging to the Ranunculaceae family. Until now there are in total 67 of chemical components identified including triterpenoids, steroids, lactones, fats and oils, saccharide and alkaloids. A broad spectrum of pharmacological activity of A. raddeana compounds have been ...
Mirza M Kamran - - 2011
Encephalitis associated with autoantibodies directed against the N-methyl-D-aspartate receptor (NMDAR) is usually a paraneoplastic syndrome that presents in young females with ovarian teratomas. We report a case of a previously healthy 14-year-old girl with sudden-onset paranoia, hallucinations, hyperactivity, increased speech, decreased sleep, seizures, and violent behavior deteriorating to catatonia. Her ...
Shiau Chii-Shinn - - 2011
Ovarian stimulation is a unique aid for patients treated for anovulation and an important tool in various assisted reproduction treatments. Clomiphene citrate, an orally active, non-steroidal triphenylethylene derivate, is a commonly prescribed agent for ovulation induction. Clomiphene citrate is considered a safe agent and has rarely been associated with significant ...
Shoimer Ilya - - 2011
Background:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous disorder characterized by giant cells in the dermis phagocytosing damaged elastin fragments.Objective:We report a case of a 71-year-old man presenting with erythematous plaques in predominantly sun-exposed areas.Method:A diagnosis of AEGCG was made based on the clinical and histologic picture, and ...
Kleinberger Andrew J - - 2011
The relationship between systemic corticosteroids and central serous chorioretinopathy (CSCR) has been well established; however, there also appears to be an association with intranasal corticosteroids. A search of the English literature revealed only three reported cases of CSCR linked to intranasal corticosteroid use, and in each, clinical improvement was observed ...
Shah Sanket D - - 2011
Steroid-responsive encephalopathy with autoimmune thyroiditis is a relatively uncommon entity in the pediatric population. Although the pathogenesis of steroid-responsive encephalopathy with autoimmune thyroiditis is uncertain, an autoimmune mechanism is suspected to be the most likely cause. Seizures of unknown etiology are a common presenting sign in the pediatric intensive care ...
Barbour Thomas D - - 2011
Glomerulonephritis occurs in 1% of Hodgkin's lymphoma patients. In the even rarer setting of rapidly progressive glomerulonephritis, lymphoma may go unrecognized. We describe a case of necrotizing glomerulonephritis in which treatment with cyclophosphamide and steroids led to resolution of lymphadenopathy. Two years later, recrudescent lymphadenopathy was shown to be Hodgkin's ...
Gupta Rahul - - 2011
Steroids are one of the most commonly prescribed medications for a variety of medical conditions, often long term. Spinal epidural lipomatosis (SEL) is a state of pathological fatty tissue overgrowth in the vertebral canal. It is a rare and dangerous complication of chronic steroid therapy that may lead to back ...
Popescu Alexandra - - 2011
BACKGROUND AND PURPOSE: To describe a growing number of cases associated with spinal cord and posterior circulation ischemia as a complication of cervical epidural steroid injection (CESI). METHODS: Case report and review of literature. RESULTS: Sixteen cases of spinal cord and posterior circulation ischemia were analyzed. Two cases had transient ...
Samala Renato V - - 2011
Amidst the ubiquitous use of steroids, psychiatric side-effects are not uncommon, though the presentation may be curiously diverse. The case of an elderly lady who had 40 mg of methylprednisolone injected in each knee for treatment of suprapatellar bursitis is presented. After 3 days, she reported visual hallucinations, which resolved ...
Azzopardi Silvan - - 2011
Complicated infantile hemangiomas require early intervention. With the advent of an improved understanding of the pathophysiology of the condition, and the serendipitous discovery of the effects of propranolol, available treatment options have expanded from the traditional use of steroids. This article reviews the current literature on the treatment of complicated ...
Guan Hui - - 2011
Mullerianosis of the urinary bladder is a rare entity characterized by the presence of an admixture of at least two types of mullerian tissue in the muscularis propria of the bladder. We report a case of mullerianosis of the urinary bladder in a 28-year-old nulliparous woman with no history of ...
Wilson Liam C - - 2011
• To review the urological literature regarding the management of Post-Prostatectomy Incontinence (PPUI). • A Pubmed literature search was performed. • The definition of Post-Prostatectomy Incontinence varied widely. • The artificial urinary sphincter has proven efficacy and durability. • Newer devices, in particular the AdVance sling, lack quality studies despite ...
Giridhar Venkatesh - - 2011
Primary leiomyosarcoma of testis is a rare entity with few cases reported in literature. Primary leiomyosarcoma of testis usually occurs following radiotherapy or long-term anabolic steroid use. Without these predisposing factors, its occurrence is rare. In the present study, we present a rare case of primary leiomyosarcoma of testis occurring ...
Al-Qattan Mohammad M - - 2011
Dorsal dimelia is a rare form of duplication along the dorsoventral axis as opposed to polydactyly and hyperphalangism which are duplications along the radioulnar and proximodistal axes, respectively. All previous cases of dorsal dimelia involved the ulnar digits. We report the first human case of dorsal dimelia of a radial ...
Bohn Olga L - - 2011
Abstract Bladder paraganglioma (BP) is a rare entity, and is exceedingly uncommon in childhood. Pheochromocytomas/Paragangliomas are components of several hereditary cancer syndromes, and up to 30% may be associated with germ line mutations of genes including VHL, RET and SDH. We present a 16-year-old female who was admitted with macroscopic ...
Robinson Lisa M - - 2012
The purpose of this literature review is to report the effectiveness of trials using the Transtheoretical Model of Change for achieving smoking cessation among adolescents. An integrative literature review was performed. Two reviewers searched the Internet for randomized, controlled trials or observational studies of adolescent smoking cessation trials reported between ...
Tsai Chia-Chun - - 2011
Pheochromocytomas and paragangliomas (extra-adrenal pheochromocytomas) are catecholamine-secreting tumors. The paraganglioma of the urinary bladder is an uncommon neoplasm with a higher malignancy rate. Only about 60% of bladder paragangliomas presented with hematuria, and most of them were microscopic hematuria. Herein, we report two cases of bladder paraganglioma with bladder bloody ...
Perrott David H - - 2011
The publisher regrets that this article is an accidental duplication of an article that has already been published, doi:10.1006/ijom.2003.0514. The duplicate article has therefore been withdrawn.
Ohba Tetsuro - - 2011
Symptomatic spinal epidural lipomatosis is a rare disorder characterized by overgrowth of fat in the extradural space. Most patients have an underlying endocrine disorder, such as Cushing's syndrome, or have taken exogenous steroids chronically. Although less common, obesity alone is thought to be a cause of spinal epidural lipomatosis, representing ...
Biondi-Zoccai G - - 2011
The hierarchy of evidence based medicine postulates that systematic reviews of homogenous randomized trials represent one of the uppermost levels of clinical evidence. Indeed, the current overwhelming role of systematic reviews, meta-analyses and meta-regression analyses in evidence based heath care calls for a thorough knowledge of the pros and cons ...
Singh Jitendra K - - 2011
Covered exstrophy is a rare variant of the exstrophy-epispadias complex. We report a female newborn with covered exstrophy, absent anal opening and duplication of the introitus and the lower vagina. This rare, previously unreported, combination of anomalies highlights the complexity of the embryological events in the caudal area during separation ...
Grubišić Igor - - 2011
There is a well-documented relationship between urinary bladder diverticula and intradiverticular neoplasms. The great majorities of these tumors are urothelial carcinomas, but may also be of glandular or squamous type. Sarcomas occurring within bladder diverticula are exceptionally rare and highly malignant lesions, with only 20 well documented cases published in ...
O'Connell M - - 2010
Tenascin-X is a large extracellular matrix glycoprotein that is widely distributed within connective tissues and is associated with an autosomal recessive type of Ehlers-Danlos syndrome (EDS). Tenascin-X represents the first EDS susceptibility gene that does not code for a fibrillar collagen or collagen-processing enzyme. We describe a paediatric case of ...
Joshi Milind - - 2010
Mayer-Rokitansky-Kuster-Hauser (MRKH) is a characteristic syndrome in which the mullerian structures are absent or rudimentary. It is also associated with anomalies of the genitourinary and skeletal systems. There are very few cases reported regarding its association with anorectal malformations, particularly perineal fistulas. To the best of our knowledge, there have ...
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