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Lipton Richard B RB Departments of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA; Departments of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA; Montefiore Headache Center, Bronx, NY, - - 2014
In this review, we focus on migraine as a chronic disorder with episodic attacks (CDEA). We aim to review methodological approaches to studying trigger factors and premonitory features that often precede a migraine attack. Migraine attacks are sometimes initiated by trigger factors, exposures which increase the probability of an attack. ...
Ely Scott S Division of Hematopathology, Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, 525 East 68th Street, Starr Pavilion, 715, New York, NY, 10065, USA, - - 2014
Assessment of minimal residual disease (MRD) is becoming standard of care for potentially curable cancers, like some leukemias. For diseases not currently curable, like multiple myeloma (MM), the optimal methodology to assess MRD is much less clear, let alone the clinical significance. In this two-part series, we review each of ...
Mertz Marcel - - 2014
The systematic review of reasons is a new way to obtain comprehensive information about specific ethical topics. One such review was carried out for the question of why post-trial access to trial drugs should or need not be provided. The objective of this study was to empirically validate this review ...
Bonilha Heather Shaw HS Department of Health Science and Research, Medical University of South Carolina, Charleston, South Carolina; Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina. Electronic address: - - 2014
Laryngeal endoscopy with stroboscopy (LES) remains the clinical gold standard for assessing vocal fold function. LES is used to evaluate the efficacy of voice treatments in research studies and clinical practice. LES as a voice treatment outcome tool is only as good as the clinician interpreting the recordings. Research using ...
Arevalo-Rodriguez Ingrid - - 2014
BackgroundDementia includes a group of neurodegenerative disorders characterized by progressive loss of cognitive function and a decrease in the ability to perform activities of daily living. Systematic reviews of diagnostic test accuracy (DTA) focus on how well the index test detects patients with the disease in terms of figures such ...
Pangallo Antonio - - 2014
This systematic review presents findings from a conceptual and methodological review of resilience measures using an interactionist theoretical framework. The review is also intended to update findings from previous systematic reviews. Two databases (EBSCOHost and Scopus) were searched to retrieve empirical studies published up until 2013, with no lower time ...
Lee Hui-Young HY Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon-si, Gangwon-do 200-947, Republic of - - 2014
Bleomycin has been used most commonly in the treatment of Hodgkin's lymphoma, certain germ cell tumors (GCT) and for the sclerosis of recurrent pleural effusions. Bleomycin toxicity predominantly affects the skin and lungs. Skin toxicity includes Raynaud's phenomenon, hyperkeratosis, nail-bed changes and palmoplantar desquamation. Flagellate erythema is an unusual rash ...
Levy Jonathan - - 2014
Background:Wolf's isotopic response is the phenomenon of a new skin disease occurring at the site of another unrelated and already healed skin disorder. Most cases in the literature report herpes zoster (HZ) as the original disease; however, the isotopic responses vary greatly. Including this case, our literature search revealed 32 ...
Sauder Maxwell B MB Division of Dermatology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: - - 2014
Lichen sclerosus is an inflammatory skin condition characterized by inflammation of the papillary dermis that leads to white scarlike plaques. It occurs classically in the genitals but also has extragenital manifestations with a variety of clinical presentations including a bullous variant. The purpose of this review is to characterize extragenital ...
Adil Hala H *Department of Dermatology, Saint Louis University, St. Louis, MO; and †Cutaneous Pathology, WCP Laboratories, Inc, St. Louis, - - 2014
: Elastoderma is a rare cutaneous condition, which clinically presents as an acquired laxity and decreased recoil of skin. It is histologically characterized by an increase of pleomorphic and fragmented elastic fibers in the superficial dermis. A case of a 61-year-old woman with wrinkled lax skin on the anterior and ...
Tuffaha Sami H SH From the Department of Plastic and Reconstructive Surgery, Johns Hopkins Medical Institutions, Baltimore, - - 2014
Pyoderma gangrenosum (PG) is a rare cutaneous disorder that poses a diagnostic challenge in the postoperative period. A systematic literature review was performed to determine distinguishing characteristics of PG in the setting of breast surgery that can facilitate timely diagnosis and appropriate treatment. PubMed, EMBASE, Scopus, and Web of Science ...
Varada Sowmya S Tufts Medical Center, Department of Dermatology, Boston, MA, - - 2014
Tinea versicolor (TV) is a common cutaneous fungal infection characterized by superficial scaling and a mild disturbance of skin pigmentation. It typically affects the chest, upper back, and shoulders. However, involvement of more unusual regions of the body such as the face and scalp, arms and legs, intertriginous sites, genitalia, ...
Wen Xiao-Heng XH Xiao-Heng Wen, Lan Wang, Jia-Ming Qian, Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, - - 2014
Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances in the gastrointestinal tract and skin. The aim of this study was to investigate the clinical features and potential therapies for CCS. Six patients with CCS admitted from December 1992 to July 2008 to Peking Union Medical ...
Yuenyongviwat Varah - - 2014
Calcific myonecrosis is a rare condition in which muscle in a limb compartment undergoes necrosis and becomes peripherally calcified with central liquefaction. The patient usually presents with a slowly progressive enlarged mass that sometimes can be misdiagnosed as soft tissue sarcoma. Most of the reported cases showed that the disease ...
Pielasinski U U Departments of - - 2014
primary effusion lymphoma is an unusual form of aggressive B-cell lymphoma universally associated with human herpesvirus 8 (HHV8) that involves mostly human immunodeficiency virus (HIV)-infected patients. Characteristically, it presents as a malignant serous effusion involving body cavities, but without associated tumor mass. Exceptionally, HHV8-positive lymphomas with features identical to primary ...
Tena Daniel D Sección de Microbiología, Hospital Universitario de Guadalajara, Guadalajara, Spain. Electronic address: - - 2014
Skin and soft-tissue infections (SSTIs) caused by Actinobaculum spp. are very rare. In the present study, we report two cases and review the literature. The first case was an immunocompromised patient with an extensive cellulitis secondary to an inguinal abscess, and the second case was a patient with a pilonidal ...
Dotan Miri M Departments of aPediatrics C bPediatric Intensive Care cPediatric Orthopedic Unit, Schneider Children's Medical Center of Israel, Petach Tikva dSackler Faculty of Medicine, Tel Aviv University, Tel Aviv, - - 2014
Acute hemorrhagic edema of infancy (AHEI) is a benign, self-limiting vasculitis that usually resolves completely without any sequelae or a need for active therapy. To our knowledge, compartment syndrome because of AHEI has not been reported. Chart data for a single case were reviewed and reported in a retrospective study. ...
Piraccini B M BM Division of Dermatology, Department of Experimental, Diagnostic and Specialty MedicineUniversity of Bologna, Bologna, Italy - - - 2014
Tazarotene is a topically-applied, receptor-selective retinoid that has been shown to modulate several major pathogenic factors of psoriasis. Adverse effects are those of topical application of retinoids, the most common being mild to moderate burning, itching, stinging, and erythema, due to mild to moderate local skin irritation. While pyogenic granuloma-like ...
Dayal Prakriti P Department of Oral Medicine and Radiology, Manipal College of Dental Sciences, Manipal University, Mangalore, - - 2014
Neurofibroma is a benign peripheral nerve sheath tumor, usually found in association with Von Recklinghausen's disease of the skin. The solitary variant commonly occurs in the head and neck region, mostly affecting young adults. They are characteristically slow-growing masses, often asymptomatic and have been found most commonly in the tongue ...
Manteghi Alexander A Division of Otolaryngology, Albert Einstein Medical Center, 5501 Old York Rd., Philadelphia, PA 19130, USA. - - 2014
Sebaceous carcinoma is a rare malignancy primarily affecting the periocular sebaceous glands. Sebaceous carcinoma of the parotid gland is exceedingly rare, with only 30 cases reported in the literature. Our case brings this total to 31. We present a case involving a 57-year-old man with a slowly enlarging, right tail-of-parotid ...
Fathi Khaled K Department of Pediatrics, Surgical Division, Tolna County Teaching Hospital, Szekszard, - - 2014
Granuloma annulare (GA) is an uncommon benign inflammatory skin condition, most often found on the extremities of young females. The subcutaneous variant of GA involving the penis is very rare. We report a case of subcutaneous GA associated with a urethral anomaly in a 15-year-old boy that persisted for a ...
Pacheco Compaña F J FJ Servicio de Cirugía Plástica, Complexo Hospitalario Universitario A Coruña (CHUAC), A Coruña, - - 2014
The incidence of contrast medium extravasation at the venipuncture site has increased with the generalized use of automatic injectors. Most extravasations only cause slight edema and erythema. Nevertheless, in some cases extravasation can result in severe skin lesions or even in compartment syndrome. Lesions caused by extravasation usually resolve spontaneously ...
Gladsjo Julie Akiko - - 2014
Biobrane is a biosynthetic wound dressing that has been widely used in burn treatment and as a skin graft donor site dressing. Our aim for this review was to establish whether Biobrane serves as a useful tool for the field of Dermatology and Dermatologic surgery. It has been frequently used ...
Kamel Haytham H Department of Urology, Alexandria University, Alexandria, - - 2014
Necrotizing fasciitis is a progressive, rapidly spreading, inflammatory infection located in deep fascia. It may cause necrosis of skin and subcutaneous tissue and can even results in involvement of adjacent soft tissues such as muscles resulting in necrotizing myositis. We report the case of an adult male presenting with necrotizing ...
Maiwald Matthias M Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, - - 2014
Chlorhexidine has attracted increasing attention for its role in skin antisepsis in recent years. It was tested in several prominent clinical trials and subsequently recommended in important guidelines for blood culture collection, vascular catheter insertion and surgical skin preparation. We noticed and subsequently reported a widespread misinterpretation of evidence surrounding ...
Buote N J NJ Nicole J Buote, DVM DACVS, 1818 South Sepulveda Blvd, Los Angeles, CA 90025, United States, Phone: +1 310 473 2951, E-mail: - - 2014
The medicinal leech, Hirudo medicinalis, has been used for hundreds of years in human medicine for a variety of diseases, most recently including venous congestion following reconstructive surgeries (skin flaps and reimplantations), excessive lingual and periorbital swelling, and non-traditional treatments for osteoarthritis, compartment syndrome and sialoadenitis. The treatment of venous ...
Macía-Villa Cristina C CC Rheumatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain, - - 2014
Multicentric reticulohistiocytosis (MRH) is a rare systemic and devastating disease with main involvement of skin and joints, frequently related with malignancies. Macrophages and TNFα are the main targets of multiple treatment options with variable results. Although MRH has the tendency of self-resolve in an average of 8 years, treatment must be ...
Nambudiri Vinod E VE Department of Dermatology, Boston Children's Hospital and Harvard Medical School, Boston, - - 2014
Milia are benign, superficial keratinaceous cysts that present as fine, small white papules. Milia en plaque is a rare, challenging-to-treat variant most often seen in the posterior auricular region. A total of 9 cases of milia en plaque have been reported in the pediatric literature to date. We report a ...
Kempf Werner W *Kempf und Pfaltz, Histologische Diagnostik, Zürich, Switzerland; †Department of Pathology, Faculty of Medicine in Pilsen, Charles University in Prague, Prague, Czech Republic; and ‡Department of Dermatology, University of Münster, Münster, - - 2014
: Mycosis fungoides (MF) displays a broad spectrum of clinical, histological, and phenotypic variants with different prognostic impact. CD8CD56 MF is very rare. So far, only 5 patients with CD8CD56 MF were reported to date. All of the previously described patients with this phenotypic variant were adults at the time ...
Chen Sheng S Department of Pathology and Laboratory Medicine and Department of Dermatology, Hofstra North Shore-LIJ School of Medicine, NY, - - 2014
Although rare isolated cases of adenocarcinoma in situ of skin have been reported in the literature, adenocarcinoma in situ of skin as a concept and as a diagnostic category has not been established in the field of dermatopathology. In this work, four cases of papillary adenocarcinoma in situ of the ...
Sharma Mayur M Department of Neurosurgery, 4 floor, Main Hospital Building, Grant Medical College and Sir J.J Group of Hospitals, Byculla, Mumbai, Maharashtra, - - 2014
To report a rare case of basal encephalocele (spheno-orbital encephalocele), managed successfully in our institute. This is one of the rarest type of encephaloceles with very little literature available. In this case, sphenoid dysplasia was not associated with type 1 Neurofibromatosis. Grant Medical College and Sir J.J Group of Hospitals, ...
Zouboulis Christos C CC Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Dessau, - - 2014
Sarcoidosis is a rare, systemic disease that is characterized by the formation of granulomas in various organs, including the skin. As the etiology remains unknown, the treatment of sarcoidosis is challenging. We present a 47-year-old female patient with progressive, multi-organ sarcoidosis who had a complete clinical improvement of the skin ...
Geller S S Departments of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, - - 2014
IgA pemphigus (IGAP) is a rare distinct variant of pemphigus, currently classified into subcorneal pustular dermatosis (SPD) type and intraepidermal neutrophilic IgA dermatosis (IEN) types based upon histological features, immunofluorescence staining pattern and autoantibodies profile. In a patient with a widespread blistering disease of the skin resembling SPD-type IGAP, we ...
Lynde Carrie - - 2014
Background:Optimal management of skin pathology demands accurate anatomic description, especially in the orbit and periorbital region.Case Report:This brief article reviews the clinically important surface anatomy of the orbit and periorbital region for the dermatologist.
Arunachalam Meena M Department of Critical Care Medicine and Surgery, Division of Dermatology, University of Florence, Florence, - - 2014
Lipoatrophia semicircularis is characterised by band-like horizontal skin depressions involving the anterior and lateral sides of the lower limbs. Whether this occurrence is rare or is just not well known or simply underreported because it does not cause patient distress is still under discussion. In a 1-year period we observed ...
Lai Jonathan H JH Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, Capital District Health Authority and Dalhousie University, Halifax, NS, - - 2014
A 65 year old male with known hypertension and hypercholesterolemia sought medical attention because of a three month history of skin swelling on his upper back. Histopathology and molecular techniques were employed and identified an organism in the Onchocerca genus. This represents a very uncommon example of cutaneous infection by ...
Mayor Jessica J Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, - - 2014
The ephemeral effects of neurotoxins and fillers are well described for facial remodeling and rejuvenation. Less is known about their long-term effects on skin rejuvenation and neocollagenesis. This article aims to review current available science and literature to support the use of these cosmetic procedures as lasting antiaging treatments.
Al Aranji Ghassan G Rheumatology Department, Waikato Hospital, Hamilton, New Zealand. - - 2014
Systemic sclerosis (SSc) is a chronic multisystem autoimmune disorder characterised by progressive functional and structural abnormalities in blood vessels leading to microvascular dysfunction, excessive production and deposition of collagen leading to the fibrosis of skin and internal organs. The aetiology of the disease is unknown. However, exposure to various environmental ...
Rysgaard Carolyn C University of Iowa Department of - - 2014
A 62-year-old male presented with a 10-day history of a diffuse, erythematous papular rash sparing the palms and soles. Histopathologic examination of a skin lesion demonstrated loose non-caseating granulomas in a lymphoplasmacytic background. Scattered spirochetes were identified by T. pallidum immunohistochemistry, in keeping with a diagnosis of secondary syphilis. Granulomatous ...
Jian Xin-Chun XC Department of Oral and Maxillofacial Surgery, Affiliated Haikou Hospital, Central South University, Haikou 520208, Hainan, People's Republic of China; Department of Oral and Maxillofacial Surgery, Xiangya Hospital, Central South University, Changsha 410008, Hunan, People's Republic of China. Electronic address: - - 2014
Median cleft lip is a midline vertical cleft through the upper lip. This is a very rare anomaly described in the literature. Median cleft lip is caused by the failure of fusion of the medial nasal prominences. In this case report, a 4-month-old boy with a median cleft associated with ...
Ozer Pinar A PA Department of Ophthalmology, Sami Ulus Children's Hospital , Altindag Ankara , Turkey - - 2014
ABSTRACT Keratoglobus is a rare condition of bilateral corneal ectasia, which results in high myopia, irregular astigmatism, scarring, and rarely spontaneous globe rupture. Globoid protrusion of a clear, diffusely thin cornea is the pathology. The congenital form has been associated with blue sclera in which there is a systemic connective ...
Jow Tiffany T From the *Department of Dermatology, New Jersey Medical School, Newark, NJ; and †Elixir Institute of Regenerative Medicine, San Jose, - - 2014
Melasma is an acquired cutaneous disorder caused by an overproduction of melanin by the enzyme tyrosinase. Melasma remains a therapeutic challenge and no definitive standard therapy exists. Although hydroquinone (HQ) has emerged as the most common treatment, its popularity has recently waned because of concerns about its potential carcinogenicity and ...
Nigam Aruna A Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, New Delhi, - - 2014
Endometriosis is a growth of endometrial tissue outside the uterine cavity which is responsive to hormonal stimulation. Extrapelvic endometriosis is less common of which skin is the most common site. The patient presents with mass, pain and cyclic symptoms. Subcutaneous endometriosis is very rare and has been reported only thrice ...
Saluja Harish - - 2014
Benign fibrous histiocytoma (BFH) is a mesenchymal tumor which commonly affects the skin of extremities. Histologically, BFH of soft tissues and bone shows similar features, but BFH of the bone is rare with less than 100 cases reported worldwide and usually it involves tibia, femur, and pelvic bone. As far ...
Torbeck Richard - - 2014
Background: Cantharidin is a topical vesicant that causes intraepidermal acantholysis with clinical application that includes the removal of warts, molluscum contagiosum (MC), calluses, and acquired perforating dermatoses. Objective: To provide a comprehensive literature review of the efficacy and safety of cantharidin in the management of various cutaneous conditions. Methods: A ...
Mafra Rogério Saint-Clair Pimentel RS Instituto Metropolitano de Ensino Superior-IMES, Ipatinga, MG, - - 2014
Melanoma is a cancer that originates from melanocytes, is predominant in adults with white skin, represents 4% of skin cancers, and has high possibility of forming metastasis. This review reports on the case of a young man, age 36 years, previously diagnosed with melanoma. The patient complained of obstructive urinary ...
Nussbaum Eric S ES Department of Neurosurgery, National Brain Aneurysm Center at the John Nasseff Neuroscience Institute, St. Paul, Minnesota, USA ; Minnesota Neurovascular and Skull Base Surgery, Minneapolis, Minnesota, - - 2014
Fusiform intracranial aneurysms (FIAs) are uncommon lesions representing less than 15% of all intracranial aneurysms in most large series. Their etiology has been linked to a variety of causes including atherosclerosis, fibromuscular dysplasia, cystic medial necrosis, connective tissue disease, hypertension, diabetes, hyperlipidemia, infection, cardiac myxoma, oral contraceptive use, vasculitis, and ...
Hathaway James A JA From Occupational Medicine Consultant (Dr Hathaway), Kendall Park, NJ; VA Medical Center (Dr Molenaar), Minneapolis, Minn; Medical College of Wisconsin (Dr Cassidy), Milwaukee, Wis; and Bayer Material Science (Mr Feeley and Ms Cummings), Pittsburgh, - - 2013
To identify possible cases of occupational asthma and assess accidental skin and inhalation exposures to aliphatic diisocyanates. Seventy-three employees from two plants, manufacturing or producing aliphatic diisocyanates, were surveyed using a detailed respiratory history questionnaire with additional questions on accidental skin and inhalation exposures. Further reviews of medical records and ...
Scognamiglio J - - 2013
A toxicologic and dermatologic review of 1-spiro[4.5]dec-7-en-7-yl-4-pent-1-one when used as a fragrance ingredient is presented. 1-Spiro[4.5]dec-7-en-7-yl-4-pent-1-one is a member of the fragrance structural group Alkyl Cyclic Ketones. These fragrances can be described as being composed of an alkyl, R1, and various substituted and bicyclic saturated or unsaturated cyclic hydrocarbons, R2, ...
Lubahn Jordon G - - 2013
To report a single case of acquired sessile hemangioma of the conjunctiva which resolved after treatment with topical timolol. Case report and literature review. A 77-year-old African American woman developed an acquired sessile hemangioma of the conjunctiva of the right eye. She was followed for primary open-angle glaucoma, and the ...
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