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Berardi Rossana R a Medical Oncology , Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria Ospedali Riuniti Umberto I-GM Lancisi-G Salesi , Ancona , - - 2015
The aim of the study was to determine the potential role of occupational exposures to chromium (Cr) in the onset of extragonadal germinal embryonal carcinoma. The first two cases of workers in a company with Cr exposure are reported. The published scientific literature regarding the topic in peer-reviewed journals including ...
Zhou Weimin W Department of Urology, Third Xiangya Hospital, Central South University, Changsha, Hunan 410013, P.R. China ; Department of Abdominal Surgery, Jiangxi Cancer Hospital, Nanchang, Jiangxi 330029, P.R. - - 2014
Metaplastic changes in the renal pelvis are infrequent and may be malignant transformations to adenocarcinoma. The current study reports a case of intestinal metaplasia in the right renal pelvis, which was associated with staghorn calculi, in a 56-year-old female. The patient underwent a percutaneous nephrolithotomy. Immunohistochemical assessment of the mucosa ...
Layfield Lester J LJ From the Department of Pathology & Anatomical Sciences, University of Missouri, Columbia. - - 2014
Certain laboratory tests are critical for patient care and must be communicated rapidly. Professional societies have developed guidelines for reporting of "critical values" and significant or unexpected surgical pathology findings. Urgent diagnoses requiring rapid reporting include new or unexpected diagnoses of malignancy. The University of Missouri established a "cancer-tracking" protocol ...
Hitchcock Thomas M TM Ulthera, Inc., Mesa, AZ, - - 2014
The Safety of Microfocused Ultrasound with Visualization (MFU-V) has been well established in both controlled clinical studies and in clinical use, showing only mild and transient anticipated side effects and only rare unanticipated adverse events (AEs). This publication discusses the safety profile of MFU-V based on data from a variety ...
Carruthers Jean D A JD Vancouver, British Columbia, Canada From the University of British - - 2014
Vascular occlusion causing blindness is a rare yet greatly feared complication of the use of facial aesthetic fillers. The authors performed a review of the aesthetic literature to ascertain the reported cases of blindness and the literature reporting variations in the vascular anatomy of the human face. The authors suggest ...
Zhang Kun - - 2014
BackgroundPatients with congenital absence of the portal vein (CAPV) often suffer from additional medical complications such as hepatic tumors and cardiac malformations.Case presentationCongenital absence of the portal vein (CAPV) is a rare malformation. We present a case of a 16-year-old Chinese girl with CAPV with multiple pathology-proven hepatic focal nodular ...
Chen Shumin S Shandong Provincial Institute of Dermatology, Shandong Provincial Academy of Medical Sciences Jinan, Shandong, - - 2014
Lichen planus pigmentosus-inversus is a rare variant of lichen planus. So far, only 24 cases from 12 reports have been documented in the published work. The prominent characteristics of the disease are dark-brown macules and patches confined to the non-sun exposed, flexural areas and skin folds with lichenoid pathological changes ...
Mathur Moses M Temple University Hospital, Department of Medicine, Section of Cardiovascular Diseases, Philadelphia, PA, - - 2014
Deep vein thrombosis related to immobilization is a common and extensively studied disorder, particularly in hospitalized patients. However, the phenomenon of iatrogenic venous compression (IAVC) and related deep venous thrombosis (DVT) is under-recognized and under-reported. In the absence of relieving the compressive pathology, the recanalization rates are expected to be ...
Bhagat Priyanka P Departments of Hematology and Internal Medicine, PGIMER, Chandigarh, - - 2014
Primary bone marrow lymphoma is a rare disease and remains undiagnosed due to deceptive clinical presentation. Here, we report four cases of primary bone marrow B-cell non-Hodgkin lymphoma, which presented with cytopenias without any lymphadenopathy or organomegaly. Bone marrow examination revealed large atypical B-cells with a reactive T-cell infiltrate with ...
Vaiman M M Department of Otolaryngology, Assaf HaRofeh Medical Center, Affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, - - 2014
The generally accepted definition of ecthyma gangrenosum (EG) states that this condition is pathognomonic of Pseudomonas septicemia (Pseudomonas aeruginosa) and that it should usually be seen in immunocompromised patients, particularly those with underlying malignant disease. The cases described in the literature present a somewhat different picture. Our objective was to ...
Jones Elizabeth E From the *Department of Medicine, †Nathan Speare Regional Burn Treatment Center, and ‡Department of Pathology, Crozer Chester Medical Center, Upland, - - 2014
Purpura fulminans (PF) and toxic epidermal necrolysis (TEN) are rare and life-threatening diseases. TEN is a notorious epidermolytic condition, most cases of which are drug induced. TEN is a more severe variant of epidermal necrolysis than Stevens-Johnson syndrome, as it affects a greater percentage of skin surface area. PF occurs ...
Gunasekera Nicole N Harvard Medical School, Department of Pathology, Brigham and Women's Hospital, Boston, Mass., - - 2014
Inflammatory vitiligo with raised borders (IVRB) is a rare subtype of vitiligo described as having a rim of raised erythema at the periphery of the depigmented patches. The etiology is poorly understood, and there are few reports of successful treatment of the condition in the literature. We report a 38-year-old ...
Huemer Martina - - 2014
BackgroundThe cblC defect is a rare inborn error of intracellular cobalamin metabolism. Biochemical hallmarks are elevated homocysteine and low methionine in plasma accompanied by methylmalonic aciduria. Due to the heterogeneous clinical picture, patients with the late-onset form of the disease (onset >12 months) come to the attention of diverse medical specialists, ...
Berie M B MB Department of Internal Medicine, Meharry Medical College, 1005 Dr. DB Todd Jr BLVD, Nashville, TN, 37208, USA, - - 2014
We describe a 52-year-old female patient who developed cardiopulmonary arrest due to neuromuscular paralysis after initiation of polymyxin B for septicemia caused by extended spectrum β-lactamase-producing Klebsiella pneumoniae. Due to emerging antibiotic resistance patterns, use of polymyxins is increasing and an understanding of their toxicity is critical.
Wollina Uwe U Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Friedrichstrasse 41, 01067, Dresden, Germany, - - 2014
Advanced squamous cell carcinoma (SCC) is a challenge for treatment. It is also a risk factor for unintended infestation with diptera larvae (maggots) known as myiasis. We performed a retrospective investigation in our files from 2001 to 2014 and identified three patients with SCC-associated myiasis (three men). In all three ...
Patel Forum F Department of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA 95817, - - 2014
Pyoderma gangrenosum (PG) is an inflammatory disease characterized by painful skin ulcerations with undermined and erythematous borders. The etiology of PG is not well understood, but it is generally considered to be an aberrant immune response characterized by a dermal neutrophilc infiltrate. Given the existence of only a few PG ...
Weaver Meaghann S MS Departments of *Oncology ‡Pathology, Children's National Health System, Washington, DC †Department of Oncology, St Jude Children's Research Hospital, Memphis, - - 2014
Although solitary presentations of infantile myofibromatosis tend toward spontaneous regression, multicentric forms fare worse. Previous case reports have depicted observation, surgical resection, and systemic therapies as treatment options. This paper reports well-tolerated, successful outcomes in a series of patients with high-risk infantile myofibromatosis in need of life-sustaining interventions treated with ...
Chung Shimin J SJ Department of Infectious Diseases, Singapore General Hospital, Singapore; Department of Laboratory Medicine, Tan Tock Seng Hospital, Singapore; National Public Health Laboratory, Ministry of Health, Singapore; Communicable Diseases Centre, Institute of Infectious Diseases and Epidemiology, Tan Tock Seng Hospital, Singapore; Yong Loo Lin School of Medicine, National University, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore - - 2014
Early diagnosis of dengue has been made easier in recent years owing to the advancement in diagnostic technologies. The rapid non-structural protein 1 (NS1) test strip is widely used in many developed and developing regions at risk of dengue. Despite the relatively high specificity of this test, we recently encountered ...
Zhao HongMei H Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, People's Republic of - - 2014
The objective of this study was to review all cases in literature in which the clinical manifestations of ischemic stroke and immune thrombocytopenia (ITP) were presented in the same patient including a new case of our own and discuss the possible mechanism and management of this syndrome. We reviewed 12 ...
Sheremata William W University of Miami, Miller School of Medicine, Department of Neurology , 1120 NW 14th Street, Miami, FL 33136 , USA - - 2014
Introduction: Outcomes of two large double-blind placebo-controlled studies of oral dimethyl fumarate (DMF) in multiple sclerosis (MS) provided the basis for its marketing approval as Tecfidera® by the US FDA in early 2013 and the European Medicines Agency in February 2014. The safety of DMF is complemented by experience in ...
Sinha Priyank P Department of Neurosurgery, Leeds Teaching Hospitals NHS Trust, Leeds General Infirmary, Leeds, LS1 3EX, UK, - - 2014
Atypical teratoid rhabdoid tumour (ATRT) is a rare and highly aggressive malignant neoplasm of the central nervous system (CNS), which occurs predominantly in children less than 2 years of age. There are less than 50 cases described in adult. We report a case of primary spinal ATRT in a 65-year-old male ...
Wooten Candace C Department of Family Medicine, University of Louisville, Louisville, KY, - - 2014
Bilateral tracheal bronchus is a rare variation of the tracheobronchial tree. We present a 1-year 7-month-old male patient who presented with sepsis following endotracheal intubation. Upon review of multidetector computed tomography images, the patient was diagnosed with displaced bilateral tracheal bronchus. Imaging showed a right-sided anomalous bronchus arising 0.9 cm proximal ...
Frydrychowicz Clara C Clinic of Neurosurgery, University Hospital Leipzig, Leipzig, Germany; Department of Neuropathology, University Hospital Leipzig, Leipzig, - - 2014
We present two cases of atypical meningioma WHO grade II with a history of multiple local recurrences and late pulmonary metastases. Comparative cytogenetic analyses on 1p and 22q confirmed clonal origin of the primary intracranial meningiomas and the pulmonary metastases in both cases. These cases illustrate the importance of close ...
Hasan Syed Shafae SS Departments of 1Medicine and 2Pathology, University of Toledo Medical Center, Toledo, OH; and 3Department of Medicine, Division of Gastroenterology, University of Toledo Medical Center, Toledo, - - 2014
Autoimmune enteropathy (AIE) is a rare disease that causes intractable diarrhea not responsive to a gluten free diet and must be distinguished from refractory sprue. It is associated with circulating autoantibodies against goblet cells and enterocytes. AIE mainly involves the small intestines, with very few cases reported in adults. Because ...
Desai Stuti V SV Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, New Jersey, - - 2014
Inflammatory pseudotumor is a benign idiopathic inflammatory process often misdiagnosed as an infection or neoplasm. This review analyzes all reported cases of sinonasal and ventral skull base inflammatory pseudotumor to date, and provides a framework for evaluation and management of this uncommon condition. MEDLINE/PubMed database. A search for articles related ...
Mahajan Vrushali V Department of Histopathology, First Floor, SSRB Block, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, - - 2014
Angiosarcoma arising in a schwannoma is extremely rare with only fourteen cases having been reported in the literature to the best of our knowledge. Amongst these fourteen, only five cases developed from vagal schwannoma. We describe a case of epithelioid angiosarcoma arising in a long standing vagal schwannoma in a ...
Jordan Robert W RW Trauma & Orthopaedics, University Hospitals Coventry & Warwickshire, Coventry, United Kingdom - - 2014
External rotation (ER) bracing has been shown to improve labral reduction in cadaveric studies, but this has not translated to universal improvement in re-dislocation rates in clinical series. To systematically review and critically appraise the literature that investigates how well the labrum is actually reduced by ER in patients who ...
Zheng Yan Y Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. - - 2014
The present study reports a case of extranodal natural killer (NK)/T-cell lymphoma, nasal type, involving the skin. The clinical manifestations, pathological characteristics, treatment and prognosis of the case were analyzed to improve the clinical diagnosis and treatment for this disease. The patient was a 56-year-old male, presenting with dark red ...
Suojanen Juho J Department of Oral and Maxillofacial Diseases, Helsinki University Central Hospital, Helsinki FIN-00014, - - 2014
Renal cell carcinomas (RCCs) have a tendency to metastasize at an early stage, therefore, the patients frequently exhibit metastatic disease at the time of diagnosis. Common locations for the metastases are adjacent organs and abdominal lymph nodes; however, occasionally metastasis to the peripheral organs may be the initial clinical symptom. ...
Guo Liwen L Department of Surgical Oncology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. - - 2014
A 62-year-old female with neurofibromatosis type 1 (NF1; also von Recklinghausen's disease) was diagnosed with a giant, thick-walled tubular mass, mainly located in the right abdominal area on computed tomography, following an examination for intermittent abdominal pain and increasing abdominal distension. According to the clinical manifestations and imaging features, the ...
Wushou Alimujiang A Department of Oncology, Cancer Research Institute, Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University, Shanghai 200032, P.R. China ; Department of Oral and Maxillofacial Surgery, College and Hospital of Stomatology, Xi'an Jiao Tong University, Xi'an, Shaanxi 710004, P.R. - - 2014
Synovial sarcomas (SS) are high-grade soft-tissue sarcomas, predominantly found in the deep soft tissues of the lower extremities, with only 3-5% occurring in the head and neck region. Primary SS of the infratemporal fossa (ITF) is exceptionally uncommon. The present study reports the case of a 23-year-old female with an ...
O'Connell Casey L CL From Jane Ann Nohl Division of Hematology and Center for the Study of Blood Diseases, University of Southern California-Keck School of Medicine, Los Angeles, - - 2014
Venous thromboembolism (VTE) is a frequent clinical complication of cancer and its treatment. Although much of the epidemiologic data regarding this complication have been based on symptomatic events, the use of multidetector row CT scanner technology has led to increased identification of VTE on scans ordered primarily for staging or ...
Adhikari Subodh S Cancer Center and Blood Institute, St Joseph Regional Medical Center, Lewiston, ID, - - 2014
Neurotoxicity is a dose-limiting side-effect of vincristine therapy. Blindness is a rare central neurotoxicity of vincristine with few case reports. In the present article, we report a rare case of vincristine-induced blindness in a patient with diffuse large B cell lymphoma. Literature search identified eleven published cases of vincristine-induced blindness. ...
Batthish Michelle M From the Division of Rheumatology, Department of Pediatrics, McMaster Children's Hospital, McMaster University, Hamilton; Division of Rheumatology, Department of Pediatrics, Department of Medicine, The Hospital for Sick Children; Dalla Lana School of Public Health; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada. M. Batthish, MD, Division of Rheumatology, Department of Pediatrics, McMaster Children's Hospital, McMaster University; S.M.L. Tse, MD, Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto; B.M. Feldman, MD, Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, Dalla Lana School of Public Health, University of Toronto; G.R. Baker, PhD, Institute of Health Policy, Management and Evaluation, University of Toronto; R.M. Laxer, MD, Division of Rheumatology, Departments of Pediatrics and Medicine, The Hospital for Sick Children, University of Toronto. Address correspondence to Dr. M. Batthish, Division of Rheumatology, McMaster Children's Hospital, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4K1, Canada. E-mail: batthim@mcmaster.ca. Accepted for publication August 1, - - 2014
To describe the frequency and types of reported adverse events and system improvement recommendations in the Morbidity and Mortality Conference (M&MC) within the Division of Rheumatology at The Hospital for Sick Children, Toronto, Ontario, Canada (SickKids). A 5-year retrospective review of the M&MC within the Division of Rheumatology at SickKids ...
Grippaudo Cristina C From the Catholic University of Rome, Rome, - - 2014
Asymptomatic idiopathic condylar resorption is a rare disease of difficult diagnosis and treatment. We review the literature about this rare condition and report a case of a patient, affected by Down syndrome, who underwent a complete untreated bilateral condylar resorption in adolescence and then developed pain on chewing only 20 ...
Bawazeer Naif A NA Faculty of Medicine, Umm Alqura University, PO Box 1129, Makkah 21955, Kingdom of Saudi Arabia. Tel. +966 (12) 5556644. E-mail. - - 2014
The malignant transformation of persistent endometriotic implants into endometrioid adenocarcinoma is rare, especially after remote hysterectomy and salpingo-oophorectomy (TAH-BSO), and there are few cases reported in the English language literature. Patients receiving estrogen replacement therapy are common among the reported cases. We present a case that demonstrates the possibility of ...
Lains-Mota Renato R Centro Hospitalar de Lisboa Ocidental. Lisboa. - - 2014
Undescended testis or cryptorchidism is a pathology usually presenting in the newborn or during childhood, rarely diagnosed in the adult man. This article pretends to perform a review of its management in the adulthood. We present two cases of man with bilateral congenital cryptorchidism diagnosed in the adult. We made ...
Tarnutzer A A AA Department of Neurology, University Hospital Zurich, Frauenklinikstr. 26, 8091, Zurich, Switzerland, - - 2014
The combination of progressive cerebellar degeneration, hypogonadotropic hypogonadism and chorioretinal dystrophy defines the rare Boucher-Neuhäuser syndrome (BNS), which has recently been linked to autosomal-recessive mutations in the PNPLA6 gene in four index patients. Here we present two novel unrelated patients with BNS, where we identified four recessive PNPLA6 mutations (3 ...
Chalayer Emilie E Service de Médecine Interne, Hôpital Nord, CHU de Saint-Étienne, 42055, Saint-Etienne Cedex 2, France, - - 2014
Peripheral cytopenias are common in systemic lupus erythematosus, but bone marrow involvement is rarely reported. Aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and characterized by an empty bone marrow. This rare but serious disease has been described as an unusual manifestation of systemic ...
Ewe Shaun Yp SY Tasmanian Eye Institute, Ophthalmology Registrar & Clinical Research Fellow, South Launceston, TAS, Australia - - 2014
We report a rare case of bilateral maculopathy that developed with the initiation of sertraline. We conducted a case report and review of the literature. A 23-year-old man rapidly developed maculopathy with associated visual blurring after the initiation of sertraline. Treatment was ceased with the patient subsequently reporting mild improvement ...
Colangeli Marco M Department of Muscolo-Skeletal Oncology, Rizzoli Orthopaedic Institute, Via Pupilli 1, 40136, Bologna, Italy, - - 2014
We report the case of an 11-year-old boy who came to our observation with localized pain in the left arm for nearly 5 months. No previous history of trauma was referred in an otherwise healthy patient. Radiographs, isotope bone-scan, computed tomography, and magnetic resonance imaging of the lesion involving the left ...
Mitchell Scott S Walsall Healthcare NHS Trust, Walsall Manor Hospital, Walsall, WS2 9PS, UK, - - 2014
Suppurative perichondritis of the pinna is a serious condition with potentially long-term cosmetic sequelae. Literature regarding the optimal treatment of these abscesses is scarce with most case series containing low numbers. This work reports the largest series from the UK to date; along with a review of recent literature. A ...
Patel Ruchi R Hackensack University Medical Center, Hackensack, NJ, USA - - 2014
To review the literature on the pharmacotherapy of bloodstream infections (BSI) caused by vancomycin-resistant enterococci (VRE). A MEDLINE literature search was performed for the period 1946 to May 2014 using the search terms Enterococcus, enterococci, vancomycin-resistant, VRE, bacteremia, and bloodstream infection. References were also identified from selected review articles. English-language ...
Asahi Takashi T Department of Neurosurgery, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Toyama, - - 2014
Background: Writer's cramp is a specific movement disorder with hand muscle cramps in writing, being classified into focal and action-specific dystonia. Stereotactic surgery, such as thalamotomy and deep brain stimulation (DBS), has been reported for writer's cramp; however, the number of reported cases is still scarce and surgical procedures are ...
Parra Marcelo M Thoracic Surgery Department, Hospital Padre Hurtado, Santiago, Chile - - 2014
We describe the rare case of a 71-year-old man with a chest mass that was found to be an intrathoracic gossypiboma left 52 years earlier during an emergency lung bilobectomy. This mass was complicated by extension across the chest wall. There are no reports in the literature of a patient ...
Zajkowska Joanna J From the 1 Department of Infectious Diseases and - - 2014
Lyme neuroborreliosis (LNB) is a rare cause of vasculitis and stroke. It may manifest as subarachnoid hemorrhage, intracerebral hemorrhage, and most often ischemic stroke due to cerebral vasculitis. The vast majority of reported cases have been described by European authors. A high index of suspicion is required in patients who ...
Maillot C C Department Ortho Rachis 2, Pellegrin Hospital, Place Amélie Raba Léon, 33076, Bordeaux, - - 2014
Gorham-Stout syndrome is an aggressive, non-heritable skeletal disease characterized by osteolysis following minor trauma. The primary involvement of the spine is less common (10 %) and has been described in only about 20 cases; there is no consensus about the best way to treat this condition. To report a case of ...
Tugcu Ali Ulas AU Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Ankara Hospital, Ankara, - - 2014
When conventional methods for treating complicated problems such as acute and chronic renal failure or metabolic diseases fail, the therapy of choice is peritoneal dialysis (PD) in neonatal period. However, in cases that involve technical difficulties, such as bulky lesions in the abdomen or complications from previous abdominal surgeries, it ...
Suero Molina Eric Jose EJ Departments of 1 Neurosurgery - - 2014
Patients with Gorham-Stout disease (GSD), a rare disease of poorly understood etiopathophysiology, suffer from progressive osteolysis. Destruction of bone matrix is caused by lymphatic vessels, which can lead to CSF leakage if parts of bony structures adjacent to CSF spaces are involved. So far, fewer than 200 patients have been ...
Leal Rui Filipe - - 2014
Uterine inversion is a rare obstetric emergency that can lead to hypovolemic shock or even maternal death. There are many management strategies, but they are poorly described and dispersed in the medical literature. The purpose of this article is to describe a case of complete acute uterine inversion and a ...
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