The case histories and blood pictures of two patients who had cardiac lesions, septicaemia, and renal failure and terminally developed a leucoerythroblastic anaemia with megloblastic features associated with multinucleate erythroblasts, are described. Though folate deficiency may have made a minor contribution to the blood abnormalities, it is considered that some ...

Haematological as well as biochemical parameters assessing anaemia associating protein energy malnutrition PEM were estimated. Data revealed that controls studied have a relatively lower Hb, Ht, and R.B.C.S. count than European standards. Hypochromic anaemia was predominant in 83.3% of moderate Kwashiorkor being normocytic in 50% and microcytic in 33.3%. In ...

A case of hemolytic disease secondary to anti-Fya in a neonate requiring exchange transfusion is presented. A review of the literature reveals 18 previous cases, with 32 per cent requiring exchange transfusion and a 16 per Fya-b- or Fya-b+ blood can be obtained for exchange transfusion if indicated.

Initial reports of patients with laminin α2 chain (merosin) deficiency had a relatively homogeneous phenotype, with classical congenital muscular dystrophy (CMD) characterised by severe muscle weakness, inability to achieve independent ambulation, markedly raised creatine kinase, and characteristic white matter hypodensity on cerebral magnetic resonance imaging. We report a series of ...

The histological features of the buccal mucosa have been examined in 50 cases of iron-deficiency anaemia, 14 cases of megaloblastic anaemia, and 50 normal subjects. Differences between the anaemic and normal groups have been found and in some anaemic patients striking morphological changes have been seen. These might be due ...