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Chalhoub Walid M WM Georgetown University Hospital, Department of Medicine, Division of Gastroenterology, Hepatology Section , 3800 Reservoir Road, NW, Washington, DC 20007 , USA - - 2014
Introduction: The year 2013 continued to highlight numerous aspects of drug-induced liver injury (DILI), with new information communicated via > 1500 publications. New reports of DILI were described and FDA warnings and alerts were issued for a number of products, emphasizing the risks related to hepatotoxicity. Areas covered: We provide ...
Crepin Sabrina S Sabrina Crepin, Pharm.D., M.P.H., is Hospital Pharmacist, Department of Pharmacology-Toxicology, Pharmacovigilance; Bertrand Godet, M.D., is Neurologist, Department of Neurology; and Paul Carrier, M.D., is Hepatologist, Department of Hepatogastroenterology, Limoges University Hospital, Limoges, France. Claire Villeneuve, M.S.I., is Clinical Research Associate; Louis Merle, Ph.D., M.D., is Pharmacologist; and Marie-Laure Laroche, Ph.D., M.D., is Pharmacologist, Department of Pharmacology-Toxicology, Pharmacovigilance, Limoges University - - 2014
A case of probable drug-induced liver injury (DILI) attributed to use of the antihypertensive agent aliskiren is reported. A 61-year-old woman undergoing routine liver function monitoring in conjunction with long-term antiepileptic therapy was noted to have an asymptomatic acute hepatic cytolysis 1 month after the initiation of concomitant aliskiren therapy ...
Morimoto Tadatsugu T 1Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga, Japan 2Department of Orthopedic Surgery, Faculty of Medicine, Fukushima Medical University, School of Medicine, 1 Hikarigaoka, Fukushima, - - 2014
Study design. Case reportObjective. To report a case of an acute supratentorial subdural hemorrhage (SDH) of a previous head injury site and cerebellar hemorrhage (CH), following an incidental dural tear during spine surgery.Summary of Background Data. Intracranial hemorrhage, such as subdural, cerebellar, subarachnoid and epidural hemorrhage following a dural tear ...
Xie Jian-Xiang - - 2014
We report a rare case of teicoplanin- induced hepatocellular liver injury in a 49-year-old male patient with pulmonary infection. Liver function returned to normal after drug withdrawal. We reviewed 17 case reports of adverse reactions associated with teicoplanin in mainland China and found that (1) among all patients 15 were ...
Wat Heidi - - 2014
Background:Pyoderma gangrenosum (PG) is a neutrophilic dermatosis commonly associated with underlying systemic illness, typically of autoimmune origin. The association of PG with autoimmune hepatitis (AIH) has been reported but remains poorly recognized.Observations:We describe a case of PG manifesting 5 years following the diagnosis of AIH and conduct a literature review ...
Chen Yuanyuan Y From the Division of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, BC, - - 2014
Cryofibrinogenemia is a rare disorder in which plasma, not serum, forms a cryoprecipitate. Patients with cryofibrinogenemia may be asymptomatic, or they may have painful ulcers, purpura, livedo reticularis, Raynaud phenomenon, perniosis of the extremities, thrombosis, and arthralgia. Cryofibrinogenemia may be primary or secondary to an underlying disorder such as connective ...
Aslan Mehmet M Medical Faculty, Department of Internal Medicine, Yuzuncu Yil University, 65000, Van, Turkey, - - 2014
Hepatotoxicity may occasionally develop over the course of treatment with proton pump inhibitors (PPIs). Although skin reactions, interstitial nephritis, pancytopenia, anaphylaxis, and generalized edema have been reported to be associated with PPIs, hepatotoxicity associated with oral pantoprazole is very rare. In this report, we present a case of hepatotoxicity in ...
Kobayashi Yujin - - 2014
Although there are several case reports of human parvovirus B19 infection in patients with hereditary spherocytosis, no systematic reviews of adult patients with hereditary spherocytosis with human parvovirus B19 infection have been published as clinical case reports. In this study, we report a case of aplastic crisis due to human ...
Malla Gyanendra - - 2014
Impalement injury is an uncommon presentation in the emergency department (ED), and penetrating thoraco-abdominal injuries demand immediate life-saving measures and prompt care. Massive penetrating trauma by impalement in a pediatric case represents a particularly challenging presentation for emergency providers in non-trauma center settings. We report a case of 10 year ...
Stanley Sharon S SS Department of General Surgery, North Shore-Long Island Jewish Health System, Hofstra University School of Medicine, Manhasset, New - - 2014
The Morel-Lavallee lesion is a closed, internal degloving injury that results when a strong, shearing force is applied parallel to the plane of injury, as is common in vehicular trauma. It is an underdiagnosed entity that is often missed during the initial trauma workup as symptoms can be subtle. There ...
Gokce Gokcen G Department of Ophthalmology, Sarıkamis Military Hospital , Kars , Turkey - - 2014
Abstract Post-traumatic endophthalmitis comprises 25-30% of all endophthalmitis cases. Post-traumatic endophthalmitis is an important clinical condition that may have serious anatomical and functional consequences. The type of pathogenic microorganism, nature of the injury, the presence of a foreign body, and the geographical region in which the trauma occurred are all ...
Shasha David D 1 The Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center , Jerusalem, Israel - - 2014
Abstract Infective endocarditis and hepatosplenic abscesses are rare manifestations of cat scratch disease (CSD), especially among immunocompetent adults. An otherwise healthy woman who presented with fever and abdominal pain was diagnosed with multiple abscesses in the spleen and the liver, as well as a mitral valve vegetation. PCR on spleen ...
Kim Dong Hwi DH Department of Orthopaedic Surgery, Chosun University Hospital, Gwangju, - - 2014
Acute simultaneous rupture of the anterior cruciate ligament (ACL) and patellar tendon is a rare injury. We present a case report of a 32-year-old male patient with ruptured ACL and ipsilateral patellar tendon rupture sustained while playing baseball. Surgery was performed on the patellar tendon and the ACL simultaneously. The ...
Nassr Ahmad A Department of Orthopedic Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905. Electronic address: - - 2014
Complications associated with C1 lateral mass screw placement are relatively infrequent. The most commonly feared complications include neural or vascular injury. While both vertebral artery and internal carotid artery injury have been discussed in the literature, there have been no reports of injury of the posterior inferior cerebellar artery (PICA) ...
Deroux A A Service de médecine interne, CHU A. Michallon, 38700 La Tronche, France. Electronic address: - - 2014
Hepatitis E (HEV) is an emerging disease in our developed countries, but is not routinely tested for in case of liver cytolysis. However, a growing number of extra-hepatic manifestations of HEV infection associated with acute hepatitis are reported. In this article, we discuss two cases of HEV with neurological symptoms, ...
Damlaj Moussab M Royal Victoria Hospital, Division of Hematology, 687 des pins, C6.82, Montreal, Quebec, Canada H3A 1A1; - - 2014
Objectives: To examine laser microdissection and mass spectrometry (LMD-MS), which has emerged as a new tool to aid in typing amyloid proteins. Results: ALECT-2 is a potential cause of hepatic amyloidosis best detected by LMD-MS. Methods: One of the more recently reported proteins is ALECT-2 (leukocyte cell-derived chemotaxin 2) amyloid, ...
Ozkırış Mahmut M Department of Otolaryngology-Head and Neck Surgery, Köşk Mah. İncirli Sok. No: 36 Mühendisler Sitesi D Blok D:16, Melikgazi, Kayseri, Turkey. - - 2014
Electrical injuries can occur as a result of contact with low- or high-voltage electricity. Low-voltage injuries are more common, as they usually occur in the home, but reports in the literature are few. After exposure to electric current, almost every organ system in the body is affected. The severity of ...
Mishra Devendra D Associate Professor, Department of Pediatrics, Panineeya Institute of Dental Sciences , Hyderabad, India - - 2014
Post-traumatic headache is a recognized sequel of all types of head injuries and reported in up to 6.8% of children with head-injuries. Two varieties, acute (resolving within 3 months) and persistent have been described. We report three cases and discuss pertinent issues for the clinicians.
Pierson Elizabeth H - - 2014
Ultrasound imaging of rhabdomyolysis has previously been reported in the literature, but differing descriptions of its appearance exist. In this report, we describe a relatively rare case of exertional rhabdomyolysis of the anterior arm muscles. This injury may appear sonographically different than more severe cases of rhabdomyolysis. Our patient was ...
Mellinger Jessica L JL Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Michigan Health System, 3912 Taubman Center, 1500 E. Medical Center Drive, SPC 5362, Ann Arbor, MI, 48109-0362, - - 2014
Acute liver failure (ALF) is a rare clinical syndrome associated with a high case fatality rate. Asymptomatic primary infection with Epstein-Barr virus (EBV) is common in the general population while acute hepatitis and jaundice are much less common and ALF has been rarely reported. We reviewed the presenting features as ...
Ekegren Christina L CL Department of Epidemiology and Preventive Medicine, Monash University, , Melbourne, Victoria, - - 2014
The use of text messaging or short message service (SMS) for injury reporting is a recent innovation in sport and has not yet been trialled at the community level. Considering the lack of personnel and resources in community sport, SMS may represent a viable option for ongoing injury surveillance. The ...
Ihama Yoko Y Department of Legal Medicine, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan. Electronic address: - - 2014
A 40s-year-old woman with previous history of injury due to contact with crown-of-thorns starfish, Acanthaster planci, was stung on the right middle finger. After immediately losing consciousness, she died 13h after injury despite intensive medical treatment. Examination of the respiratory system revealed narrowing due to severe edema of the laryngopharynx, ...
Kaar Courtney R J CR Saint Louis University Medical School, St. Louis, MO (Ms - - 2014
"Noodling" is an ancient form of hand fishing recently gaining in popularity as a hobby and sport. We present one of the first case reports of a noodling injury in an adolescent male seeking to land a large catfish, and also review the literature on catfish-related injuries.
Côté-Daigneault J J Hepatology Service, Department of Medicine, Saint-Luc Hospital, CHUM, University of Montreal, Montreal, Quebec, - - 2014
Herpes simplex virus (HSV) hepatitis is an uncommon cause of liver failure, but may have a dramatic outcome. We herein present a case report of a liver graft infection by HSV-1 associated with liver failure and encephalitis. A complete hospital chart review of the case and a literature search were ...
Quigley Alan J AJ In-Patient Radiology Department, Aberdeen Royal Infirmary, NHS Grampian, Aberdeen, AB25 2ZN, UK, - - 2014
Radiology plays a key part in the investigation of non-accidental injury. Many normal variants and artefacts can simulate an abnormality associated with non-accidental injury. It is essential that radiologists reporting skeletal surveys in cases of suspected child abuse are aware of these. We present a pictorial essay to aid the ...
Coehlo Fernanda Hack - - 2014
Malignant melanoma (MM) with multiple metastases (including the oral mucosa) is an extremely rare condition that is difficult to manage due to its complexity. This article presents the case of a 27-year-old man who first developed MM on the scalp, which subsequently metastasized to the mandible, parotid gland, infratemporal fossa, ...
Gomes Manuel Mendes MM Serviço de Medicina Interna, Centro Hospitalar e Universitário de Coimbra, Coimbra, - - 2014
Q fever is a zoonosis caused by Coxiella burnetii. It often manifests as a flu-like syndrome; other common manifestations are pneumonia, hepatitis and endocarditis. Its course may be acute or chronic. The authors present two clinical cases of Q fever with rare manifestations. Case 1: A 55-year-old man admitted due ...
Patsatsi Aikaterini A 2nd Department of Dermatology and Venereology, Aristotle University School of Medicine, Thessaloniki, - - 2014
Ichthyoses are a heterogeneous group of cutaneous keratinization disorders that can be congenital or acquired. Apart from neoplastic disorders, the acquired form of ichthyosis (AI) has been associated with a variety of diseases including infections, autoimmune/inflammatory and endocrine/metabolic diseases as well as nutritional conditions, medications and others. However, malignancy accounts ...
Marques Evelyne Gsc EG Division of Plastic Surgery, Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo - - 2014
Victims of electrical burns account for approximately 5% of admissions to major burn centers. The first case of visceral injury caused by electrical burns was described in 1927 by Simonin, who reported perforation of the small intestine. Other rare cases were reported over the following years. The colon and small ...
Thompson Meghan C MC Center for Injury Research and Policy, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America; The Ohio State University College of Medicine, Columbus, Ohio, United States of - - 2014
To evaluate the National Electronic Injury Surveillance System's (NEISS) comparability with a data source that uses ICD-9-CM coding. A sample of NEISS cases from a children's hospital in 2008 was selected, and cases were linked with their original medical record. Medical records were reviewed and an ICD-9-CM code was assigned ...
Boynton James R - - 2014
Traumatic dental injuries are common among children in the mixed dentition. A case is described outlining treatment of avulsion of immature maxillary and mandibular incisors in an 8-year-old child. Resources to aid the dentist to easily locate the most recent evidence-based treatment recommendations are described.
Limani Perparim P Division of Visceral and Transplantation Surgery, Department of Surgery, University Hospital Zurich, Zurich, - - 2014
Patients diagnosed with neuroendocrine tumors (NETs) with hepatic metastases generally have a worse prognosis as compared with patients with nonmetastasized NETs. Due to tumor location and distant metastases, a surgical approach is often not possible and nonsurgical therapeutic strategies may apply. The aim of these systematic reviews is to evaluate ...
Tompkins Andrew J - - 2014
Bowel-related injuries are known complications of suprapubic tube (SPT) catheterization placement. A literature review was conducted to determine identifiable risk factors for bowel injury. Results on the analysis of 25 cases are presented along with a proposed algorithm to aid in choosing between open, percutaneous, and image-guided methods of placement.
Hafez Mahmoud A MA The Orthopaedic Department, October 6 University, Giza 11787, - - 2014
Gluteal compartment syndrome is a serious but rare condition that has recently been increasingly reported in literature. This report presents two cases that followed neurological and vascular injuries (first case: an injury of the superior gluteal artery; second case: neurological injury bilaterally). A high index of suspicion and attention is ...
Dayal Madhukar M Department of Radiodiagnosis (Madhukar Dayal, Raju Sharma, Kumble Seetharama - - 2014
Rupture into the portal vein is a rare complication of a pancreatic pseudocyst. Only 15 cases of such an incidence have been described in the literature. Only one of these was diagnosed with magnetic resonance imaging (MRI), the rest being diagnosed using other invasive diagnostic modalities or at surgery. We ...
Kayalar Murat M Hand Microsurgery Orthopedics and Traumatology (EMOT) Hospital, İzmir, Turkey. - - 2014
Traumatic hemipelvectomy is a severe, life-threatening injury, mainly occurring due to machinery injury or traffic accident. Few cases have been published in the literature. Treatment requires a rapid, multidisciplinary team approach which will result in the saving of the patient's life. We present the outcome of a male patient with ...
Schulman Joshua M JM Department of Dermatology, University of California, San Francisco, CA, - - 2013
Graft-vs-host disease (GVHD) is a rare and often fatal complication of orthotopic liver transplantation (OLT). The skin is frequently involved early in disease progression, but clinical and histopathological features may be nonspecific, presenting a diagnostic challenge. While the detection of peripheral blood chimerism has been proposed as a diagnostic criterion ...
Villaverde Doménech M E ME Department of Plastic and Reconstructive Surgery, La Fe Hospital, Bulevar Sur s/n, Valencia, Spain. Electronic address: - - 2013
With this case report we want to emphasize the importance of performing a thorough physical examination of the burn and detailed review of the patient's history. This is a challenging case because it deals with an uncommon disease nowadays, pellagra, which presents lesions with an appearance very similar to burns; ...
Douros Antonios A Department of Clinical Pharmacology and Toxicology, Charité-Universitätsmedizin Berlin, Berlin, - - 2013
The hepatotoxic potential of the analgesic flupirtine has attracted increased attention over the past years. Recently, risk minimisation measures such as maximum treatment duration of 2 weeks have been requested by the European Medicines Agency (EMA). This study was conducted to further elucidate the clinical pattern of flupirtine-induced liver injury (FILI). ...
Zhang Chao C Department of Urology, Daping Hospital, Institute of Surgery Research, Third Military Medical University, Chongqing, 400042, China, - - 2013
Intra-peritoneal bladder and visceral injuries from impalement of the perineum in women are exceedingly rare. This kind of injury has not been previously reported in a pregnant woman. The evaluation and surgical management of a pregnant woman is a challenging surgical problem. Preoperative evaluation of the uterus and fetus is ...
Gheju I I 3rd Department of Surgery, Clinical Emergency Hospital, Bucharest, - - 2013
The authors present a case of grade IV traumatic spleen rupture (AAST-OIS) and an Injury Severity Score of 21 and a Revised Trauma Score RTS=7.841, which was managed without surgery, but with proximal splenic angioembolization (SAE), with a positive outcome. Indications, types and side-effects of SAE are also discussed with ...
Atiee Genna G Department of Small Animal Clinical - - 2013
Histoplasmosis is the second most common fungal infection reported in the cat. The disseminated form involving lung, liver, lymph nodes, spleen, and bone marrow is a frequent manifestation of the disease. Limited information is available in the literature regarding the ultrasonographic appearance of the spleen in cats with disseminated or ...
Oteir Ala'a O - - 2013
Cervical spinal cord injuries may result in life-threatening situations and long-term disability. Prehospital spinal immobilisation is the standard of care for patients with potential spinal cord injury (SCI). It aims to prepare patients for transport, achieve neutral spinal alignment, and reduce movement and secondary injuries in potentially unstable spines. However, ...
Ward Christina M CM Department of Orthopaedic Surgery, Regions Hospital, University of Minnesota, 640 Jackson St., St. Paul, MN 55130 - - 2013
We present a rare injury involving a volar dislocation of the distal capitate with secondary median nerve compression. The injury was not recognized on the initial radiographs resulting in a delayed diagnosis and treatment. A satisfactory outcome was achieved following open reduction and internal fixation via dorsal and palmar approaches. ...
Cha Jae Hwang JH Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, - - 2013
Glycogenic hepatopathy (GH) is an uncommon cause of serum transaminase elevation in type I diabetes mellitus (DM). The clinical signs and symptoms of GH are nonspecific, and include abdominal discomfort, mild hepatomegaly, and transaminase elevation. In this report we describe three cases of patients presenting serum transaminase elevation and hepatomegaly ...
van Marcke C C Department of Gastroenterology, Clinique St Luc, Bouge, Namur, Belgium. - - 2013
We present the case of a patient who died from multiple organ failure due to acute liver failure as a result of malignant hepatic infiltration by an adenocarcinoma. A review of the literature revealed that the clinical picture, laboratory examination, and imaging studies do not contribute to the diagnosis of ...
Porcel Chacón Rocío - - 2013
Neonatal lupus erythematosus is an infrequent disease seen in newborns. It is caused by transplacental maternal autoantibody passage. Cutaneous involvement and congenital heart block (CHB) are the most common affections, although it may involve multiple organs like the liver, lungs, blood, nervous or digestive systems. This article present a review ...
Zheng Lin - - 2013
Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. Although metformin-associated gastrointestinal upset and metabolic acidosis is widely recognized side effect of this drug, metformin-induced liver injury has been rarely reported in the literature. In most cases reported, metformin-induced liver injury ...
Rubio-Palau Josep - - 2013
Pseudoaneurysm of the superficial temporal artery is an uncommon complication of a blunt trauma. It usually presents as a pulsating mass in the frontotemporal area a few weeks after the injury. Doppler ultrasonography, angiography, or computed tomographic angiography can aid or confirm the diagnosis. The treatment of choice is the ...
Liu Daren D Department of Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang, Hangzhou 310009, P.R. - - 2014
Perivascular epithelioid cell tumor (PEComa) is a rare tumor that originates from mesenchymal tissues. Cases of PEComa in the liver are extremely rare. The present study aimed to analyze the clinical features of PEComa in the liver and discuss its management. Here we report a 25-year-old female with multiple lesions ...
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