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Rai Ruju R *Department of Ophthalmology, David G. Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye and Ear Infirmary; †Department of Ophthalmology, Harvard Medical School; and ‡ Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, - - 2014
Ocular tick infestation is a rare occurrence. The authors report a case that is unique for being the first published example from New England, for its chronic presentation, and for the inclusion of histopathologic analysis in its diagnostic workup. A 75-year-old man was evaluated for a persistent eyelid growth secondary ...
Matthys Erin E From the *Department of Medicine, Mercy Medical Center, Baltimore, MD; †School of Medicine and Health Sciences, and ‡Department of Dermatology, Medical Faculty Associates, George Washington University, Washington, - - 2014
Foot dermatitis is a widespread condition, affecting men and women of all ages. Because of the location, this condition may present as a debilitating problem to those who have it. Allergic contact dermatitis involving the feet is frequently due to shoes or socks. The allergens that cause shoe dermatitis can ...
Sutton Jared J Madigan Army Center, Department of Emergency Medicine, Tacoma, - - 2014
A 2 year old fully immunized male with no personal history of chicken pox presented to the emergency department with a chief complaint of a rash for one week after returning from a hiking trip in a remote island in Canada. After initially being diagnosed with contact dermatitis, a diagnosis ...
Contino Christopher C Atlantic Emergency Associates, Atlantic City, New Jersey (Mr Contino); Virtua Atlantic Shore Family Practice, Northfield, New Jersey (Dr Bradbury-Golas); and Graduate Nursing, APRN Program, Felician College, Lodi, New Jersey (Dr - - 2014
Rashes are one of the most common presenting symptoms in the emergency department setting; they may be a primary diagnosis or a symptom of systemic disease. Accurate diagnosis of a rash may be challenging and requires clinical acumen, systematic history and physical examination, and judicious use of diagnostic testing. This ...
Kemp Ann M AM aDepartment of Family Medicine bDivision of Clinical Immunology and Allergy, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, - - 2014
This review aims to provide an evidence-based overview of several pharmacotherapeutic options available for refractory anaphylaxis when intramuscular epinephrine, the drug of choice, fails to provide resolution of signs and symptoms. The evidence base for the therapy of anaphylaxis is comparatively weak and is largely based on consensus expert recommendations ...
Morshedi Maud M MM Department of Radiology, University of California, San Diego Medical Center, 200 West Arbor Drive, San Diego, CA 92103-8756. Electronic address: - - 2014
Placement of a prophylactic retrievable inferior vena cava (IVC) filter was requested in a 73-year-old woman with nickel hypersensitivity resulting in a clinical dilemma. Given that all retrievable filters contain nickel, the published literature and the Manufacturer and User Facility Device Experience (MAUDE) database were reviewed; no documented case of ...
Manchette Anastasia M AM Department of Pharmacy, Massachusetts General Hospital, Boston, - - 2014
No published information exists to support the safe use of ticagrelor in patients with a clopidogrel allergy. This study involved an institutional review board-approved retrospective review of patients with a documented clopidogrel allergy who subsequently received ticagrelor between July 2011 and February 2014. We report the cases of two patients ...
Erdogan Seyda S Department of Pathology, School of Medicine, Cukurova University, Adana, - - 2014
Well-differentiated papillary mesothelioma is an uncommon tumor of the testes that usually presents as a hydrocele. Here, we present the case of one patient who did not have a history of asbestos exposure. The tumor was localized in the tunica vaginalis and was composed of three pedunculated masses macroscopically. Microscopically, ...
Laftah Z Z St John's Institute of Dermatology, Guys and St Thomas' Hospital, Westminster Bridge Road, SE1 7EH, - - 2014
allergic contact dermatitis to metals including gold is well recognised, however pseudolymphoma reactions remain rare with only a small number of cases reported in the literature. Cutaneous pseudolymphoma, also known as cutaneous lymphoid hyperplasia, is characterised by an inflammatory response to a known or unknown stimulus resulting in a benign ...
Moscato Gianna G aDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia bOccupational Physician's Division, Local Health Authority of Sassari, Sassari cDepartment of Cardiologic, Thoracic and Vascular Sciences, University of Padua, Padua dFormerly Occupational Allergology Unit, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, - - 2014
Anaphylaxis is a severe form of allergic reaction that may cause death. Main triggers of anaphylaxis have been reported to also cause occupational anaphylaxis (OcAn). The purpose of this article was to summarize the current scientific evidence on OcAn and review the specific literature published in 2012 and 2013. Allergens ...
Makatsori Melina M aSection of Allergy and Clinical Immunology, Imperial College London bNational Heart and Lung Institute, Royal Brompton Hospital, London, - - 2014
Allergen immunotherapy has been shown to be an effective treatment for respiratory allergies and Hymenoptera venom allergy. However, concern regarding its potential to cause anaphylaxis may limit its use. This review aims to assess whether anaphylaxis is still a worry when administering subcutaneous (SCIT) and sublingual immunotherapy (SLIT). Retrospective surveillance ...
Yu Ryan R Department of Pathology and Molecular Medicine, McMaster University , Hamilton, ON, - - 2014
We report a case of cutaneous lymphadenoma on the posterior left ear of a 67-year-old woman. Although it is benign, recognition of cutaneous lymphadenoma is important as it presents a diagnostic pitfall to the unsuspecting dermatologist and general surgical pathologist, who may readily misdiagnose the lesion because it is not ...
Joseph R H RH Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, - - 2014
SUMMARY Orf virus has a worldwide distribution among sheep and goats. The hypersensitivity reaction erythema multiforme (EM) is a known complication of orf infection in humans; however, its occurrence is poorly understood and has not been extensively reviewed. We present two unrelated cases of orf-associated EM, and a review of ...
de Groot Anton C AC Acdegroot Publishing, Schipslootweg 5, 8351 HV, Wapserveen, The - - 2014
Octocrylene is an ultraviolet (UV)B and UVAII absorber that was introduced some 15 years ago, and is now widely used in sunscreen agents and skin care cosmetics. Since 2003, several studies, notably from France, Belgium, Spain, and Italy, have reported an increasing number of patients with photocontact allergy to octocrylene. This ...
Sajic Dusan - - 2014
Expert diagnosis of cutaneous pathology requires precise anatomic description. This brief report will review the clinically relevant surface anatomy of the ear.
Vaidya Madhuri - - 2014
Anaphylactic-like reaction or anaphylactoid reaction resembles generalized anaphylaxis but is not caused by immunoglobulin E-mediated allergic reaction. This reaction is caused by a non-immunologic mechanism even after first exposure to antigen. Prostaglandin E2 (dinoprostone) gel is commonly used for pre-induction cervical ripening. We report a case of anaphylactiod reaction after ...
Weiss Vivian L VL Department of Pathology, Vanderbilt University Medical Center, Nashville, - - 2014
Juvenile xanthogranuloma (JXG) is a common histiocytic disorder of infancy and early childhood, most frequently presenting with cutaneous lesions. Whereas involvement of several visceral sites is well documented, only 4 cases of primary testicular JXG have been reported. Although this benign disorder typically presents with a favorable clinical outcome, the ...
Veraldi Stefano S Department of Pathophysiology and Transplantation, University of Milan, Cà Granda Ospedale Maggiore Policlinico, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) (Italian Research Hospital Foundation), Milan, - - 2014
Centipedes are arthropods belonging to the class Chilopoda. Approximately 3000 species have been described. Centipedes are found more commonly in tropical and subtropical countries. Centipedes possess venomous fangs. The Scolopendra represent the best-known genus of centipede. We describe two cases of severe skin reactions caused by Scolopendra subspinipes bites. Both ...
Loredana Asztalos Manuela M Department of Pediatrics, St. Christopher's Hospital, Philadelphia, - - 2014
Jellyfish envenomation often causes an immediate painful vesiculopapular eruption. Less commonly it can cause a type IV allergic hypersensitivity that manifests with delayed or recurrent cutaneous lesions at the primary site or distant from the primary site. These secondary reactivations may be related to high antijellyfish immunoglobulin levels, intracutaneously sequestered ...
Lachapelle Jean-Marie JM Department of Dermatology Catholic University of Louvain Cliniques Universitaires Saint-Luc 10, Avenue Hippocrate B-1200 Brussels - - 2014
Over recent years, interest in the use of antiseptics has been reinforced as these molecules are not concerned by the problem of bacterial resistance. Whereas the in vitro efficacy of antiseptics has been well-studied, much less is known regarding their irritant and allergenic properties. This review provides an update on ...
Kaufman A Y AY Endodontics and Dental Traumatology Department, Graduate School of Dentistry, Rambam Health Care Campus, Haifa, - - 2014
Allergy to materials used during root canal treatment is well recognized in the endodontic literature. However, allergy to Ledermix paste, a compound containing triamcinolone (a corticosteroid) and demeclocycline (a tetracycline antibiotic), has not been reported apart from one very recent case in a Letter to the Editor of a journal. ...
Curtis Susanna S Department of Medicine, Montefiore Medical Center, Bronx, - - 2014
Gemcitabine is a chemotherapeutic agent used for treatment of a variety of malignancies. It has been associated with multiple cutaneous reactions including rash, alopecia, and pruritus. Less commonly, gemcitabine has been associated with "pseudocellulitis," a noninfectious skin inflammatory reaction, which resembles cellulitis. The majority of cases reported in the literature ...
Thankachen Jincy J Departments of 1Medicine and 2Cardiovascular Diseases,St Luke's Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, - - 2014
We describe the presentation, diagnosis, management, and treatment of a 62-year-old woman with a medical history of gout who presented with a maculopapular rash, facial and tongue edema. Her initial presentation, coupled with a history of recent allopurinol use for systematic relief, led to the diagnosis of allopurinol-induced drug rash ...
Altman Katherine A KA Northwest Asthma and Allergy Center and University of Washington, Seattle, WA - - 2014
Abstract Background: Angioedema is a serious medical condition characterized by recurrent non-pitting tissue edema. Hereditary (HAE) forms of this disorder are potentially fatal. Methods: PubMED, Up to Date and Cochrane Library databases were used to identify scholarly peer reviewed original research or review articles on angioedema. Search terms used were: ...
Li Ning N Department of Laboratory Medicine, Yale University School of Medicine, New Haven, - - 2014
Transfusion reactions in pediatric populations have not been well studied. We investigated the incidence and type of transfusion reactions to platelets (PLTs) in a pediatric inpatient population. Over 1 year, a retrospective review of all PLT transfusions given to pediatric inpatients (≤18 years old) was performed at a single institution with ...
Vitaliti G G Paediatric Operative Unit and Emergency Room, Policlinico-Vittorio Emanuele Hospital, University of Catania, Italy. Electronic address: - - 2014
In the past few decades, the prevalence of allergic diseases has deeply increased, with a key role played by food allergies. Legumes seem to play a major role towards the overall increase in the scenario of food allergy, since they are an appreciated source, consumed worldwide, due to their high ...
Gokalp Hilal H Ministry of Health. Malatya Government Hospital, Malatya, - - 2014
Allergic contact dermatitis related to para-phenylendiamine (PPD) from temporary black henna tattoos and hair dyes has become an epidemic in recent years. Several cases of adverse skin reactions to PPD have been reported in the literature. Herein, we present a case of angioedema-like allergic contact dermatitis related to hair coloring ...
Abbiati Giorgio G Dipartimento di Scienze Farmaceutiche, Sezione di Chimica Generale e Organica "A. Marchesini", Università degli Studi di Milano, Via Venezian, 21 - 20133 Milano, - - 2014
Silver and gold salts and complexes mainly act as soft and carbophilic Lewis acids even if their use as σ-activators has been rarely reported. Recently, transformations involving Au(I)/Au(III)-redox catalytic systems have been reported in the literature. In this review we highlight all these aspects of silver and gold-mediated processes and ...
Wood Andrew A *Department of Pathology, Western General Hospital, Edinburgh, United Kingdom; †Department of Plastic Surgery, St Johns Hospital, Livingston, United Kingdom; and ‡Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, United - - 2013
: The application of decorative tattoos to the skin is an ancient practice, which continues to be popular in the present day. Increasingly, a number of complications of tattoo application are recognized, including a diverse variety of cutaneous hypersensitivity reactions to tattoo pigments. Herein we describe an unusual case of ...
Seok Jae Yeon JY Department of Pathology, Gachon University Gil Medical Center, Incheon, - - 2013
The Prototheca species is achlorophyllic algae and rarely causes human infection. Human protothecosis presents clinically as a cutaneous infection, olecranon bursitis, and disseminated systemic disease. We report a case of human cutaneous protothecosis involving the left wrist. A 68-year-old man presented with an ill-defined erythematous lesion with crust at the ...
Kheir Fayez - - 2013
Phenytoin was introduced in 1938 for the control of seizure disorders and remains widely used today. Since that time, many cases of phenytoin-induced allergic reactions and clinical pulmonary disease have been reported. However, pulmonary vascular pathology from phenytoin use has been only very rarely described. We report a case of ...
Shlyankevich Julia - - 2013
: Scleromyxedema is a rare and frequently disabling disease characterized by generalized waxy papules, skin induration, and cardinal histological features of dermal fibroblastic proliferation, thickened collagen, and mucin deposition. A monoclonal gammopathy is almost always present with rare progression to multiple myeloma. We describe the case of a 54-year-old man ...
Fuchs Joan - - 2013
Literature on bird spider or tarantula bites (Theraphosidae) is rare. This is astonishing as they are coveted pets and interaction with their keepers (feeding, cleaning the terrarium or taking them out to hold) might increase the possibility for bites. Yet, this seems to be a rare event and might be ...
Li Wenfei - - 2013
: We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and feet for 2 ...
Lessa Priscila Pacheco PP University of Taubaté, University Hospital of Taubaté, Dermatology Service, TaubatéSP, - - 2013
The authors describe a case of a female patient with Acral Pseudolymphomatous Angiokeratoma of Children, known as APACHE. It is a rare benign cutaneous disease, of unknown etiology, characterized by multiple, asymptomatic erythematous-violaceous papules and nodules, usually located unilaterally with acral distribution. Today, this denomination is questionable, since there are ...
Azari Amir A AA Department of Ophthalmology and Visual Sciences, University of Wisconsin, - - 2013
Conjunctivitis is a common problem. To examine the diagnosis, management, and treatment of conjunctivitis, including various antibiotics and alternatives to antibiotic use in infectious conjunctivitis and use of antihistamines and mast cell stabilizers in allergic conjunctivitis. A search of the literature published through March 2013, using PubMed, the ISI Web ...
Merika E E - - 2013
Primary cutaneous amyloidosis of the penis is a rare entity. We describe two cases of primary penile cutaneous amyloidosis presenting as localized lesions on the penis and not associated with systemic amyloidosis. A comprehensive literature review of all published cases shows that the rarest form of cutaneous amyloidosis, nodular amyloidosis, ...
Lightner Donita D - - 2013
Mannitol is used for increased intracranial pressure and prevention of nephrotoxicity. We present a case report of a patient who experienced an anaphylactic response to mannitol and review the literature.
Kong L M - - 2013
5-aminosalicylates (5-ASA) remain an important strategy in the induction and maintenance of remission of inflammatory bowel diseases especially in ulcerative colitis. The prototypical drug of this class, sulfasalazine is generally well tolerated with severe hypersensitivity reactions and hepatotoxicity also described within the literature. When approaching a patient with an adverse ...
Khan Nadeem Ullah - - 2013
Anaphylaxis is a potentially fatal condition requiring immediate resuscitation. Data regarding the epidemiology of anaphylaxis are limited and inconsistent. A reason for the variability was unavailability of a universally acceptable case definition till 2005. We reviewed cases using this new definition AIM: To review the incidence, clinical presentation, cause and ...
Palmiere Cristian - - 2013
In forensic pathology routine, fatal cases of contrast agent exposure can be occasionally encountered. In such situations, beyond the difficulties inherent in establishing the cause of death due to nonspecific or absent autopsy and histology findings as well as limited laboratory investigations, pathologists may face other problems in formulating exhaustive, ...
Bose Sumit - - 2013
Proton pump inhibitors (PPIs) are widely used for the treatment of gastroesophageal reflux disease and peptic ulcer disease. PPIs are well tolerated, but they can cause hypersensitivity reactions (HSRs). Although simply avoiding a PPI after an HSR is appropriate for most patients, there are clinical scenarios that require treatment with ...
Nakajima Akira - - 2013
Hypersensitivity pneumonitis is defined as an allergic lung disease that occurs in response to inhalation of fungal antigens, bacterial antigens, chemicals, dusts, or animal proteins. The incidence of summer-type hypersensitivity pneumonitis is higher in the summer season, especially in Japan, due to the influence of the hot and humid environment ...
Urbina F - - 2013
This review of the literature on palmoplantar hypokeratosis, a process that was first indentified only 10 years ago, discusses the current state of our understanding, the therapeutic options available, and the debate about etiology. Forty-four publications reporting 69 cases were found. Palmar or plantar hypokeratosis occurs mainly in women (76.8%) ...
Bassas-Vila J - - 2013
Neutrophilic eccrine hidradenitis (NEH) is a nonspecific clinicopathological reaction pattern, classified as a neutrophilic dermatosis, that usually develops in patients receiving chemotherapy for a hematologic malignancy. More rarely, it has been reported in association with infectious agents such as Serratia and Enterobacter species, Staphylococcus aureus, and human immunodeficiency virus. We ...
Ferreira Dos Santos Luís - - 2013
The authors present two cases of purulent pericarditis secondary to pneumococcus pneumonia, a rare entity in the antibiotic era, one of them in an apparently healthy person. A systematized diagnostic approach to moderate pericardial effusion is presented, together with a review of purulent pericarditis. The presence of pericardial effusion with ...
Dyer J E - - 2013
Instillagel(®) (CliniMed, High Wycombe, UK) is commonly used in urethral catheterisation and to facilitate the passage of instruments into the bladder in urological practice. Its active ingredients include 0.25% chlorhexidine, 2% lidocaine, 0.06% methyl hydroxybenzoate and 0.025% propyl hydroxybenzoate. We discuss the case of an 84-year-old man who received intraurethral ...
Tu Honggang - - 2013
Dermatitis herpetiformis (DH) is an autoimmune disease that clinically manifests as pruritic vesicles and papules. The diagnosis of DH is often challenging because of its wide spectrum of clinical presentations. We here report 2 patients with DH in whom finger petechiae represented the initial and leading manifestation of the disease, ...
An Seo-Young - - 2013
A 10-year-old boy presented with a swelling on the right side of the jaw. He had undergone excision of the lesion about 10 months ago at a private dental clinic and the swelling began to regrow 4 months after surgery. A panoramic radiograph revealed 4 sclerotic round masses with radiolucent rims surrounded ...
Bittencourt Maraya de Jesus Semblano Mde - - 2013
Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was ...
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