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Wenderfer Scott E - - 2010
C1q nephropathy was originally described nearly 25 years ago by Jennette and Hipp. Since that time there have been a limited number of publications on C1q nephropathy, most of them in the pediatric literature. Despite reported incidences as high as 16% in some pediatric biopsy series, a consensus definition on ...
Patel Ajay Jitendra - - 2010
Blastomycosis, a worldwide disease caused by the inhalation of Blastomyces dermatitidis spores, can be diagnosed by microbiologic culture or morphologic identification in tissue or cytologic material. A retrospective review of cases diagnosed as blastomycosis in surgical pathology and cytopathology was undertaken at a University Medical Center to assess the diagnostic ...
Smith Maurice A - - 2010
Liposarcomas of the esophagus are rare with only 19 cases reported in the English literature. We present a giant, well-differentiated liposarcoma of the esophagus with multiple pedunculated polypoid-like growths, which made it radiographically and pathologically noncharacteristic. We discuss the diagnostic dilemmas, clinical and pathologic findings, and surgical treatment.
Harris Edwin J - - 2010
The frequent occurrence of flexible flatfoot raises the question of its pathologic status. There may be cultural overtones resulting in the consideration that flat feet are always pathologic. Parents may believe that their own flat feet were successfully treated when they were children and wish the same for their offspring. ...
Davidovitch Roy I - - 2010
This report questions the cost and effectiveness of routinely sending explanted hardware to pathology for evaluation. Forty-six consecutive patients who had symptomatic hardware removed were enrolled in this study. Pathology reports following hardware removal were obtained, and charts were reviewed for these patients. The pathology department was contacted for related ...
Takei Hidehiro - - 2010
Dual pathology has previously been reported in less than 10% of cases of Rasmussen's encephalitis (RE). Given the rarity of RE, it appears unlikely that dual pathology in RE is merely a coincidence. We therefore reviewed all cases of RE experienced in our institution to assess for an additional/associated pathology. ...
Lagstein Amir - - 2009
We use a case-based format to review 4 relatively common, diagnostic challenges in surgical pathology of nonneoplastic lung diseases. All cases are linked to virtual slides so that the reader can participate in a manner that simulates the breakout session held at the 2008 New Frontiers in Pathology course at ...
Gu Shuo - - 2010
Desmoplastic infantile astrocytoma is a rare low-grade malignant brain tumor found in infants. Its pathological diagnosis can be made on the basis of its histological characteristics and immunohistochemical staining. A case of desmoplastic infantile astrocytoma, including its clinical manifestations, pathological characteristics, differential diagnosis, treatment, and prognosis, is reported. Presurgical percutaneous ...
Han Seunggu J - - 2010
This report presents the historical experience, clinical presentation, treatment, prognosis, and pathogenesis of gliosarcoma described to date in the English literature. PubMed query of term "gliosarcoma" was performed, followed by a rigorous review of cited literature. Articles selected for analysis included: (1) case reports of gliosarcoma, (2) review articles of ...
Syed Omar N - - 2009
Pneumocephalus in the absence of a recent intracranial or intrathecal procedure is a significant radiographic finding and may be clinically relevant. Pneumocephalus secondary to intravenous catheterization may be a more common finding than previously expected. Although pneumocephalus is often associated with pathological conditions, recognition of a characteristic pattern of intravenous ...
Sehgal Virendra N - - 2009
Chondrodermatitis nodularis is a common condition in clinical practice but rarely discussed or reported in the literature. It most often affects the helices and antihelices of the ear. It is either uni- or bilateral. Injury usually initiates or triggers the disease. Microscopic pathology supplements the clinical diagnosis. Its etiopathogenesis points ...
Graham Anna R - - 2009
Virtual slide telepathology is an important potential tool for providing re-review of surgical pathology cases as part of a quality assurance program. The University of Arizona pathology faculty has implemented a quality assurance program between 2 university hospitals located 6 miles apart. The flagship hospital, University Medical Center (UMC), in ...
Lueck Nathan - - 2009
Mandatory review of outside pathologic material is intended to detect interpretive errors that may have a clinically significant impact on patient care. Prior to definitive treatment of referred patients, the University of Iowa Carver College of Medicine requires a review of pertinent pathologic material previously obtained at outside institutions. The ...
Miller D Chris - - 2009
Isolated epididymitis is a very rare presentation of Wegener granulomatosis (WG). Only 1 such case has been previously reported. We report a case of epididymitis in which WG was not suspected clinically or pathologically at orchiectomy, and the patient subsequently developed pulmonary involvement with WG. WG was ultimately diagnosed and ...
Batistatou Anna - - 2009
In order to survey the diagnostic reporting of melanomas by European pathologists and assess their current practice and opinions on the information required in the final report, a web-based questionnaire was diffused through the members of the Dermatopathology Working Group of the European Society of Pathology. Forty replies from different ...
Prakash Sanjay - - 2009
Hemicrania continua (HC) is an indomethacin responsive primary headache disorder. Secondary or symptomatic HC is associated with another neurological or non-neurological disease. We report three patients with secondary HC. We also review the literature to identify the clinical predictors of an underlying disease entity. Intracranial structural lesion, head and neck ...
Etgen Thorleif - - 2009
Cervical injury is a serious and often fatal complication of ankylosing spondylitis in the setting of minor trauma. This case report describes a 51-year-old woman with ankylosing spondylitis and a minor trauma who developed severe bradycardia during positioning for x ray. Further diagnostic revealed a hyperextensive fracture of C4 with ...
Ross A H - - 2009
PURPOSE: To report a series of patients with bilateral lacrimal gland uptake of Gallium (67Ga) Citrate in patients without ocular pathology and to assess the degree to which this can be a normal phenomenon. METHODS: We present an index case of lacrimal gland uptake of Gallium (67Ga) Citrate in a ...
Acharya Jayati - - 2009
Erlotinib, a specific epidermal growth factor receptor tyrosine kinase inhibitor, is used to treat various metastatic cancers. It is known to cause an acneiform rash. Herein, we report a case where the rash spared the previous radiotherapy field. A limitation of this study is that it is an anecdotal case ...
Iwasaki Yasushi - - 2009
A clinical diagnosis of Creutzfeldt-Jakob disease (CJD) can be established readily in typical cases but not in atypical cases. To investigate the accuracy of clinical diagnosis of CJD, such diagnoses were evaluated retrospectively in autopsy cases. Sixty cases were clinically diagnosed as cases of CJD, of which seven were excluded ...
Ramakrishna H K - - 2008
Gastrointestinal duplications are rare but interesting clinical entities. They have a varied presentation, with most of them showing up in paediatric population. Clinical features may vary from asymptomatic abdominal masses to bowel obstruction or perforation. This review traces the embryological origin and describes the anatomical types of duplications. An outline ...
Hazani Ron - - 2008
The use of injectable liquids for cosmetic purposes has been described by numerous clinicians informing the public of its destructive consequences. Several reports of layperson injections have come out recently indicating that the practice is still prevalent worldwide. Reports of self-administration of various liquid agents appear to have a unifying ...
Zarow Chris - - 2008
Hippocampal sclerosis (HS) is a pathologic term used to describe severe loss of neurons and reactive gliosis without cystic cavitation in the CA1 sector of the hippocampus. In late life, HS is associated with hippocampal atrophy, severe amnesia, and slowly progressive dementia without clinical seizure activity. HS is difficult to ...
Handel LiAnn N - - 2008
The identification of female urethral diverticula remains a challenging problem for many clinicians. Many of these patients are often undiagnosed or misdiagnosed due to a clinical presentation that frequently mimics other pathologic processes. There can be significant variation in the urethral diverticular anatomy in terms of size, location, and configuration. ...
Page B P - - 2008
We present four cases of profuse gastrointestinal (GI) bleeding where the site of haemorrhage was demonstrated using multi-slice computed tomography (MSCT), with concordant findings at laparotomy and pathological examination. A review of the current literature is undertaken and the role of spiral computed tomography as a method of sourcing the ...
Denewer Adel - - 2008
Mammary ductoscope allows visualization of the breast ductal wall and sampling of the abnormal area for diagnostic purposes. We are reporting our center experience in application of mammary ductoscope in detecting the underlying etiology of pathologic nipple discharge. Between November 2005 and December 2006 a total of 54 women, with ...
Goldmeier David - - 2008
There have been a number of case reports published recently describing women who complain of persistent genital arousal. Most of these papers do not report medical data or observations from genital examination. We report in such detail on six cases of persistent genital arousal disorder (PGAD) in women. We further ...
Curvers Wouter L - - 2008
OBJECTIVE: The quality of Barrett's surveillance relies on an adequate endoscopic inspection, obtaining a sufficient number of biopsy specimens, good communication of the endoscopic findings to the pathologist, and an accurate description of the histological findings by the pathologist. The aim of this study was to assess the quality of ...
Fujishiro Hiroshige - - 2008
There is limited information on the validity of the pathologic criteria of the Third Consortium on Dementia with Lewy bodies (CDLB), and none are based on prospectively diagnosed cases. In this study, the core clinical features of dementia with Lewy bodies (DLB) and the suggestive clinical feature of rapid eye ...
Manion Elizabeth - - 2008
Second opinion in pathology is intended to expose clinically significant errors that have a direct impact on patient care. Before definitive treatment of referred patients, our institution requires a second opinion of outside surgical pathology slides. We sought to determine if this local standard of practice has a measurable impact ...
Yunker Warren K - - 2008
Inconsistencies in pathology reporting can contribute to treatment delays and, potentially, inadequate or inappropriate postoperative therapy for patients with malignant disease. Given their importance, there is growing interest in optimizing the reproducibility and readability of pathology reports. The purpose of this study was twofold: (1) to assess the quality and ...
Karim R Z - - 2008
AIMS: Although the synoptic format is being increasingly used for primary cutaneous melanoma pathology reporting, no study assessing its value has yet been reported in the literature. The aim was to determine whether the use of synoptic reports increases the frequency with which pathological features that may influence prognosis and ...
Valenstein Paul N - - 2008
CONTEXT: Eighty-two million surgical pathology and cytology reports were issued in the United States during 2007; a subset of these reports will be misunderstood by readers. Recent attention has focused on standardizing the content of pathology reports, particularly for common malignancies, to facilitate transmission of required information. Comparatively little attention ...
Fujino Yasuhiro - - 2008
Microvacuolation is relatively common in the limbic lobe in Lewy body disease (LBD). Similar pathology has also been reported in Alzheimer's disease (AD). Almost all of the studies of microvacuolation in AD, however, antedated the routine application of sensitive immunohistochemical methods to detect Lewy bodies. This raises the possibility that ...
Ketcham Catherine M - - 2007
The expansion of the scientific literature has produced a concomitant increase in the number of review articles. One may posit that the sheer number of review articles belies their function. This study examines the growth of the review literature, what types of journals publish these papers, and provides data on ...
Dubois S - - 2007
We present the clinical, biological, endocrinal and psychological characteristics of a 48,XXYY adult. The 43-year-old male examined is the first reported case of this XY polysomy concomitant with type 2 diabetes. Endocrine investigations suggested dysfunction of Leydig and Sertoli cells whereas the pituitary function appeared normal. We compare the phenotypic, ...
Calder Kenneth B - - 2007
Molluscum contagiosum may present in a variety of clinical and pathologic guises. We present the clinicopathologic features of an unusual case that initially was misinterpreted as bowenoid papulosis. The relevant histologic attributes of this case include the presence of a violaceous hyperplastic squamous epithelium adjacent to the infected keratinocytes. The ...
Probst Alphonse - - 2007
Hippocampal sclerosis (HpScl) is characterized by neuronal loss and gliosis in CA1 and subiculum of the hippocampus, and may be one contributing factor to dementia in old age. The term hippocampal sclerosis dementia (HpSclD) designates the presence of both hippocampal sclerotic lesions and a dementia syndrome. In the present review, ...
Singh Vivekanand - - 2007
BACKGROUND: The passage of tissue per vaginam in a young girl raises several diagnostic considerations that include aborted pregnancy, benign polyp, rhabdomyosarcoma, and rarely decidual cast. CASE: A 9-yr-old girl who was receiving depot medroxy-progesterone acetate to suppress menstruation passed tissue per vaginam. Pathological examination of the tissue showed a ...
Jhang Yunsook - - 2007
Paraproteinemia potentially causes peripheral neuropathy via an unknown underlying pathogenetic mechanism. We report a case of pathologically proven amyloid neuropathy with AL amyloidosis with an IgA kappa light chain, which was initially diagnosed as neuropathy associated with monoclonal gammopathy of undetermined significance. This case indicates that in cases of neuropathy ...
Teot Lisa A - - 2007
The practice of central histopathologic review by expert pathologists has accompanied entry of patients onto multi-institutional therapeutic research protocols for the past half-century, and it is still a key component in the majority of therapeutic protocols conducted by the Children's Oncology Group (COG). Policies regarding pathology review have historically varied ...
Silaghi-Dumitrescu Radu - - 2007
Ferryl (Fe(IV)=O) species are involved in key enzymatic processes with direct biomedical relevance; among others, the uncontrolled reactivities of ferryl Mb (myoglobin) and Hb (haemoglobin) have been reported to be central to the pathology of rhabdomyolysis and subarachnoid haemorrhage. Rapid-scan stopped-flow methods have been used to monitor the spectra of ...
Steven Sims H - - 2007
The mucopolysaccharidoses are comprised of hereditary disorders joined by errant degradation of mucopolysaccharides. The relatively infrequent opportunity to care for these patients is evidenced by a fairly small number of case reports and anecdotal information. Though lifespan is increasing, onset of respiratory pathology or involvement remains portentous. We present two ...
Thomas Carys W - - 2007
PURPOSE: To evaluate the clinical impact of pathology review before prostate brachytherapy. METHODS AND MATERIALS: Original and reviewing pathologists' reports were retrospectively collected from 1323 men treated with prostate brachytherapy between July 1998 and October 2005 at one institution. Statistical analysis was performed pre- and post-January 2002. The clinical impact ...
Kornstein Michael J - - 2007
CONTEXT: Identifying medical errors is a topic of current attention. Among the various approaches is the study of medical malpractice cases. OBJECTIVE: To identify the most common medical errors involving the practice of pathology from a medicolegal perspective by analysis of published jury verdict and settlement reports. DESIGN: Search approximately ...
Teot Lisa - - 2007
The practice of central histopathologic review by expert pathologists has accompanied entry of patients onto multi-institutional therapeutic research protocols for the past half-century, and it is still a key component of the majority of therapeutic protocols conducted by the Children's Oncology Group (COG). Policies regarding pathology review have historically varied ...
Paparella Michael M - - 2007
Otosclerosis occurring with other pathologies has received little attention in the literature although these concomitant occurrences can be clinically relevant. We studied the clinical and histopathological characteristics of 182 cases of otosclerosis from our human temporal bone collection, and found 81 (44%) to have associated pathologies. Clinical pathological findings included ...
Reinecke Robert D - - 2007
We document, as an autobiographical case report, a 72-year history of migraine and its changing nature. Minor neurological events have waxed and waned, causing repeated searches for pathology, but instead reconfirming an intact central nervous system. In this case it appears that visual migraine auras do not reflect severity of ...
Zervoudis S - - 2007
Pathologic nipple discharge presents a diagnostic dilemma as no one diagnostic test has proven clearly superior to any other in the differentiation of benign versus malignant conditions. This is a clinical study of 80 patients with unilateral suspicious nipple discharge whose complete investigation included histological evaluation. A transnipple approach was ...
Giannikas D - - 2007
Trigger wrist is a relatively rare phenomenon. The pathological entities to which the term trigger wrist is applied are not well defined in the literature. We present three cases of trigger wrist as a result of flexor tendon pathology, review the literature and discuss the use of the term "trigger ...
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