Two adult patients with pericarditis caused by beta-lactamase producing Haemophilus influenzae are reported and their management reviewed. Both had pharyngitis, epiglottitis, pneumonia, empyema, or septicemia and were cured with antimicrobics and pericardial drainage (one by catheter and one by surgery). Eleven previously reported cases of pericarditis caused by Haemophilus influenzae ...

Four cases of amnionitis due to Lactobacillus sp and three cases of bacteremia are reported. Postpartum endometritis developed in all four cases. Lactobacillus bacteremia occurred in two infants. A review of the literature on serious infections due to Lactobacillus sp is also presented. The importance of considering the clinical role ...

Pericardial effusion is an unusual complication of meningitis due to Neisseria meningitidis. Primary meningococcal pericarditis without signs of meningitis is rare. Only 18 cases have been described in the literature. The first case was reported in 1939 and the others since 1971. We report a case of primary meningococcal pericarditis ...

A 55-year-old female recipient of an orthotopic liver transplant, who was receiving azathioprine, prednisone and cyclosporin, developed bacteremia due to Listeria monocytogenes. Because of a penicillin allergy, the patient was treated primarIly with trimethoprim-sulfamethoxazole, to which she responded well. The prior literature on use of trimethoprim-sulfamethoxazole in listeria infections is ...

The occurrence of two rare entities in a single patient can be fortuitous or may signify some deeper relationship. A young boy was recently treated for primary Candida meningitis. Autopsy findings suggested to an experienced pathologist the presence of chronic granulomatous disease (CGD), unrecognized during his life. The patient's identical ...

We reviewed 135 cases of acute community-acquired bacterial meningitis at a municipal teaching hospital during a six-year period, with special emphasis on promptness of initial antimicrobial therapy. Overall mortality was 5% for the 121 childhood cases, compared to 43% for the 14 adult cases (P less than .001). The mean ...

Information on 62 bacteriologically confirmed cases of bacterial meningitis treated with cefotaxime in this country was obtained retrospectively from infectious disease consultants. This series of cases differed markedly from the world cumulative case data thus far presented. One of the two most common organisms treated was the pneumococcus (allergy to ...

Pericarditis associated with Neisseria meningitidis in the absence of meningitis or meningococcemia is an extremely rare event. We report herein a case of a 59-yr-old woman with primary meningococcal pericarditis caused by Neisseria meningitidis group C. The patient responded to a course of penicillin therapy and recovery was uncomplicated. The ...

The case of a 67-year-old man with underlying carcinomatous meningitis who presented with meningismus and cerebrospinal fluid (CSF) eosinophilia is reported. CSF eosinophilia can reflect a number of underlying conditions; however, carcinomatous meningitis is not generally considered. In this case, studies for bacterial, fungal and parasitic agents were negative. Cytologic ...

Anaerobiospirillum succiniciproducens is a little-known spiral bacterium. Presented here are two septicemia cases similar in that both occurred in rural northern Virginia, both patients presented with dental infection, and in both cases the organism was first suspected to be Campylobacter. The morphology, motility, biochemical, and growth characteristics of Anaerobiospirillum are ...

Virological investigations (immunofluorescence reactions and isolation attempts with pharyngeal exudate specimens, as well as serological tests) were performed in 110 adult patients with pneumonia. Viral or inframicrobial agents were involved in 70 (63.7%) of the cases, either alone (27 cases) or in association with bacteria (43 cases). Parainfluenza and adenoviruses ...

Meningeal hemangiopericytoma (HP) has mostly been viewed as a variant of meningioma. There is more and more evidence, however, that HP constitutes a separate entity among tumors of the central nervous system. The data of intracranial and spinal HP of 17 of our patients and from a review of the ...

The case of a six-year-old boy who developed meningitis three months after a skull fracture is reported. Blood and cerebrospinal fluid yielded Pasteurella ureae. A two-week intravenous course of ampicillin and chloramphenicol resulted in full recovery. Two of the other four cases of Pasteurella ureae meningitis reported in the literature ...

One hundred and twenty cases of pneumatocoele, admitted, treated and followed-up at the Lagos University Teaching Hospital in 1981 are presented. Radiologically the pneumatocoele cases were associated with either the bronchopneumonic or lobar/segmental pattern of pneumonia. There were significant differences between these patterns in respect of the time of occurrence, ...

A case report of a healthy 33-year-old man with Mycoplasma pneumoniae pneumonia who concomitantly had the acquired Pelger-Huet anomaly develop is presented. Up to 31% of his total white blood cell count was comprised of Pelger-Huet cells at the height of his clinical illness. The Pelger-Huet cell count returned to ...

A patient with tuberculous oesophagopulmonary communication diagnosed by oesophagography and confirmed by endoscopy was successfully treated by medical means: a tuberculous aetiology was suggested by the detection of tubercle bacilli in the gastric washings and on culture. On reviewing the medical literature, successful results were reported in 3 adults and ...

A case of acute bacterial meningitis following Pantopaque myelography is reported, and the literature reviewed pertaining to this uncommon but potentially fatal complication. A positive Gram's stain is most helpful in differentiating bacterial from chemical meningitis. Treatment of the meningitis before and after determination of its cause is described. Preventive ...

A case of CNS listeriosis in a 49-year-old man, previously in good health, is described. The illness showed a biphasic clinical pattern with a prodromal phase characterized by headache, fever and leukocytosis and subsequent development of pontomedullary cranial nerve paresis. The infection was rapidly progressive and fatal. Gram-positive rods, identified ...

Since 1972, there has been an increased incidence of meningococcal disease due to the minor serologic groups, "serogroups," of Neisseria meningitidis. Few cases, however, have been reported in pediatric patients. We present 24 cases of meningococcal meningitis, ten of them (42%) due to serogroups X, Y, and Z N meningitidis. ...

Eighty-four pediatric patients with bacterial meningitis were prospectively evaluated while receiving cefuroxime (200 mg/kg/day in four equal intravenous doses) as single-drug therapy for 9 to 13 days. Six cases were admitted in extremis and died within a few hours because of irreversible central nervous system damage or shock. The remaining ...

All cases fulfilling stated criteria for encephalitis and aseptic meningitis in Olmsted County, Minnesota, for the period 1950 through 1981 were identified. This is, to our knowledge, the first such incidence and trend study in a delineated population, providing rates per 100,000 person-years of 7.4 for encephalitis (189 cases) and ...

A rare case of septicaemia with meningitis caused by Neisseria flavescens is reported. The clinical presentation and initial bacteriological findings were indistinguishable from those in meningococcal septicaemia with purpura. A review of the literature for N. flavescens infections revealed 15 other cases of meningitis and 1 of septicaemia. A plea ...

In October 1981, an outbreak of 29 cases of community-acquired pneumonia occurred among adult residents of Johnson County, Iowa. Retrospective study revealed 12 cases (41 per cent) had laboratory evidence of Legionnaires' disease (LD). No significant differences in clinical or epidemiological features were found between LD cases and the other ...

Thirty-eight antigenically distinct viruses have been described as adenoviruses, though only about one third have been commonly associated with human illnesses. In mid-January 1981, adenovirus 16, one of the more rarely encountered ones, was isolated from three patients in separate hospitals in the Little Rock, Arkansas, area, even though it ...

In the first quarter of 1983, four (17%) of 24 cases of Neisseria gonorrhoeae infection diagnosed in female adolescent detainees in King County, Washington were caused by penicillinase-producing (PPNG) strains. Twelve (3%) of 397 reported cases of female gonorrhea in the rest of King County during this time were caused ...

Cefotaxime, a third generation cephalosporin antibiotic, was evaluated in 26 infants and children for the treatment of documented or suspected bacterial infections, including pneumonia (10 cases), soft tissue skin infection (13 cases), and urinary tract infection (3 cases). An average daily dose of 60 mg/kg in 3 to 4 divided ...

Using an objective scoring system, chest radiographs were reviewed in 23 cases of pneumonia due to the Pittsburgh pneumonia agent (PPA, Tatlockia micdadei, Legionella micdadei), including six cases of pneumonia with simultaneous isolation of PPA and L pneumophila (Legionnaires' disease). Infiltrates were typically segmental to lobar; nodular infiltrates were noted ...

The authors report the brain findings in six cases of familial erythrophagocytic lymphohistiocytosis (FEL) and review the literature, focusing primarily on the neurologic and neuropathologic aspects. Clinically, the most common neurologic abnormalities in the six patients were stupor or coma and seizures, with hemiplegia and cranial nerve palsies. Neuropathologic changes ...

The majority of lower respiratory tract infections (LRTI) are treated "blindly" because the establishment of an aetiological diagnosis is not possible in most cases. The rational choice of therapy mainly rests upon the knowledge of the microbiological epidemiology of LRTI, and on the possible host-parasite relationship. In community-acquired pneumonia, there ...

Data on the bacteriological findings, diagnostic measures and clinical course of 875 patients with bacterial meningitis are presented. Findings from the medical records and from a follow-up questionnaire survey of 667 of these cases revealed no significant difference between patients treated with antibiotics before admission (pretreated) and those who were ...

We saw an unusual case of spontaneous Hemophilus influenzae purulent pericarditis in an adult. Counterimmunoelectrophoresis (CIE) of the pericardial fluid may be used to make an early, accurate diagnosis. Treatment should include pericardectomy and immediate use of both ampicillin sodium and chloramphenicol sodium succinate, until the sensitivity of the organism ...

Two cases of pericarditis associated with Hemophilus influenzae bacteremia and pneumonia are reported and the literature reviewed. Both patients were treated with antibiotics alone and had resolution of their illnesses without apparent adverse sequelae. Neither patient required pericardial drainage. It is suggested that there is a stage in the development ...

Between 1962 and 1980, 50 children admitted to Strong Memorial Hospital had a pleural effusion or an empyema associated with pneumonia. Such parapneumonic effusion and empyema accounted for 52 per cent of cases of pleural effusion and empyema of all etiologies admitted during those years. Review of cases of parapneumonic ...

A case of fatal meningitis and septicemia with group JK Corynebacterium species in a leukopenic patient is reported. The strain was susceptible to rifampicin and vancomycin only. The finding of diphtheroids in bacteriological samples from immunocompromised patients should not be ignored. The literature regarding meningitis caused by diphtheroid bacilli is ...

Nosocomial pneumonia caused simultaneously by two organisms, Legionella pneumophila and the Pittsburgh pneumonia agent, was documented in seven patients in one institution. In all seven cases, both organisms were demonstrated by isolation from culture or visualization by direct immunofluorescence. Four patients died as a result of pneumonia, including two who ...

Eosinophilic meningitis is rare in Hodgkin's disease. Five previous cases have been reported. We describe an additional patient whose CSF showed an eosinophilic pleocytosis with Reed-Sternberg cells while in complete systemic remission from Hodgkin's disease. The patient responded to intrathecal administration of methotrexate given by Ommaya reservoir. Six months later, ...

Aspergillosis of the cerebral ventricles developed in a 36-year-old heroin abuser who died during the sixth week of illness. The diagnosis was not made during life. A review of our case and of four previous cases from the literature indicates that aspergillosis should be considered in parenteral drug abusers with ...

Tuberculous meningitis was diagnosed in a 16-year-old patient with symptoms and signs of a space-occupying process of the right hemisphere. Cranial computed tomography demonstrated focal encephalitis of the right temporoparietal region. The case reminds that tuberculous meningitis can present itself under uncommon neurologic syndromes and should, even in the presence ...

The first reported case of Pasteurella ureae meningitis associated with endocarditis is described. The patient pursued a fulminant deteriorating course despite appropriate antibiotic therapy begun within 24 h of presentation. Previous reports of Pasteurella ureae meningitis are reviewed. This organism should be considered in the differential diagnosis of gram-negative meningitis, ...

We report a case of Listeria monocytogenes meningitis in an apparently healthy 3-year-old boy. This is the first case reported in English literature where adequate evaluation of immune status did not reveal an immunologic defect. The patient is in the age group least affected by an opportunistic organism and has ...

Between January 1968 and December 1977, 635 cases of acute bacterial meningitis were admitted to hospitals in the Birmingham Area Health Authority. The epidemiology of these cases was analysed and compared with the 270 cases which were admitted to the regional infectious diseases unit at East Birmingham Hospital (E.B.H.). In ...

Hemophilus influenza is the causative organism in only 7%-11% of the cases of pyogenic pericarditis in children. A total of 36 cases have been reported in the literature since 1942. This report analyzes those cases, adds four more (ages 8 mo, 4 yr, 5 yr, and 7 yr), and recommends ...

A case of purulent meningitis in an adult caused by Streptococcus MG-intermedius, also known as Streptococcus milleri, is described. The intriguing taxonomical history of this organism and its association with mycoplasma pneumoniae pulmonary infections is reviewed. The incidence of central nervous system infections due to this organism is also discussed.

Congenital CSF otorrhea is seldom the cause of meningitis but has to be looked for especially if associated with a dead ear or with recurrent meningitis. Polytomograms of the mastoids are essential to rule out any abnormality of the internal ear. Three patients with a congenital CSF otorrhea and associated ...

Three cases of pyogenic Haemophilus influenzae meningitis in adults have been diagnosed within the Brisbane Metropolitan area in the last twelve months. This had been considered a very unusual cause of meningitis in adults which has not previously been recorded in the Australian literature, and should alert clinicians to a ...

A case is described of sudden unilateral deafness associated with Mycoplasma pneumoniae. The hearing function of the patient returned to normal on the third day of treatment with tetracycline. M pneumoniae is a common causative agent of protean respiratory disease and the true incidence of hearing loss in these cases ...

The Slidex-méningite-Kit allows the used of the rather highly sensitive and specific latex-agglutination method for the detection of N. meningitis group A and C and H. influenzae b exoantigens within a few minutes. In model experiments positive results persisted at unchanged intensity for prolonged periods of time regardless of storage ...

A small series of nine cases of tuberculous meningitis with hydrocephalus is presented in which a ventriculoatrial shunt was carried out. Upadhyaya valves were used. Four of these nine cases are doing well and are normal 1 1/2 to 2 years after surgery. Two of them remained spastic and athetotic ...

A 13-month-old child with Neisseria meningitidis developed bilateral metastatic endophthalmitis. Treatment with systemic and periocular injections of penicillin G and steroids resulted in resolution of the meningitis and the endophthalmitis. This case should alert the pediatrician to the possibility of binding endophthalmitis in a patient with meningitis and ocular abnormalities.

Legionella pneumophila is transmitted by aerosolization of water or dust from soil. There are six serotypes and four newly recognized related organisms. Sporadic cased of Legionnaires; disease are more common than epidemic case and are less likely to be suspected . Most reporters cases are characterized by severe pneumonia. Bacteriologic ...