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Bushnell Cheryl - - 2014
Thrombosis of the dural sinus and/or cerebral veins (CVT) is a rare but potentially devastating type of stroke that tends to occur in young adults, especially women. In this article, the abbreviation CVT refers to either cerebral venous thrombosis or dural sinus thrombosis. The purpose of this review is to ...
Sahin Neslin N Sifa University School of Medicine, Izmir; Department of Radiology. Electronic address: - - 2014
We report a 48-year-old woman presenting with subarachnoid hemorrhage (SAH) as the first manifestation of superior sagittal sinus thrombosis. In a literature review of 73 cases, SAH associated with cerebral venous thrombosis (CVT) was usually seen at the cerebral convexities. SAH was adjacent to thrombosed venous structures; therefore, the most ...
Rath Claus - - 2014
Pacemaker lead malpositioning may lead to severe clinical adverse events. Rarely, cases of inadvertent placement of a lead into the left ventricle are reported in the literature. We herein report a case of pacemaker lead malpositioning into the left ventricle via a persistent foramen ovale in a male caucasian patient. ...
Chang Grace G Harbor-UCLA Medical Center, Torrance, California, - - 2014
Phlegmasia cerulea dolens (PCD) is an aggressive and life-threatening form of venous thrombosis complicated by ischemic necrosis. Massive thrombosis extends to collateral veins resulting in venous congestion with fluid sequestration in the interstitium causing collapse of arterioles, which progresses to ischemia and, if severe, circulatory collapse and shock. The mortality ...
Beqqal K K MD, Dermatologist, APHP, Department of Dermatology, Hospital Cochin, Paris Descartes University, Paris, France, Department of Dermatology, Ibn Sina Hospital, University of Mohammed V-Souissi, Rabat, - - 2014
In the setting of protein C deficiency, skin necrosis, which occurs most often at the initial phase of oral anticoagulants therapy, is a rare side effect. Six cases have previously been reported in the literature. In this case report, we present a protein C deficient 42-year-old woman who was being ...
Struijk-Mulder M C MC Department of Orthopaedic Surgery and Traumatology, Isala Clinics, Zwolle, the - - 2014
Introduction: There is a paucity of data regarding the risk of deep vein thrombosis during hip plaster cast immobilisation. The purpose of this article was to review the available evidence regarding the incidence of symptomatic venous thromboembolism (VTE) during hip plaster cast immobilisation. Methods and Materials: All papers describing hip ...
Hadjigeorgiou Georgios F GF Department of Neurosurgery, Red Cross Hospital, Athens, - - 2014
Mild traumatic brain injury is common in elderly patients, many of whom are on anticoagulant. The common practice is to discharge these patients from the emergency room if the computed tomography (CT) of the brain is normal. However, a very small proportion of these patients may develop a life threatening ...
Protopapa Muaria Nuikoletta MN Department of Internal Medicine, University Hospital of Patras, Rio Patron, 26500 Patras, Greece. - - 2014
Cytomegalovirus-associated thrombosis has been extensively reported in the medical literature, mainly in immune-compromised patients. However, the association with splenic infarcts has been rarely mentioned. We report the case of a 38-year-old Caucasian man of Hellenic origin with acute cytomegalovirus infection presenting with spontaneous splenic infarcts. Echocardiography did not show any ...
Akita Koji K Division of Cardiology, Department of Internal Medicine, National Defense Medical College, - - 2014
We herein describe a case of acute spinal subdural hematoma (SSDH) during the administration of high-dose corticosteroids and intravenous heparin for the treatment of active lupus nephritis. After SSDH was promptly diagnosed using magnetic resonance imaging (MRI), the patient recovered well with conservative treatment involving the discontinuation of heparin sodium. ...
Ashrafzadeh Farah F Department of Pediatric Neurology, Mashhad University of Medical Sciences, Mashhad, IR - - 2013
Cerebral sinovenous thrombosis (CSVT) in children has rarely been reported in the literature, especially without underlying disorder. It has increasingly been diagnosed due to clinical awareness and sensitive neuroimaging techniques. The aim of this article was to report a case of cerebral sinovenous thrombosis without underlying disorder. We reported a ...
Nyo Myat Tun Lin - - 2013
Severe thrombocytopenia with bleeding associated with a life-threatening thrombotic manifestation in the setting of antiphospholipid syndrome is a major diagnostic and therapeutic challenge for the clinician. Hemorrhage is a less common complication than thrombosis in patients with APS, although severe thrombocytopenia can sometimes result in bleeding. There are no evidence-based ...
Kitamura Aki - - 2013
Pseudoaneurysm of the hand is rare, with only a few cases reported in the literature, and is usually related to trauma. Early treatment is recommended for pseudoaneurysm after it is diagnosed. We report the surgical treatment of spontaneous pseudoaneurysm of the hand in a patient on anticoagulant therapy.
Wool Geoffrey D - - 2013
Objectives: To review various anticoagulation therapies and related laboratory monitoring issues, with a focus on factor X-related chromogenic assays. Methods: A case-based approach is used to review pertinent published literatures and product inserts of anticoagulation drugs and to look back on clinical use of factor X-related chromogenic assays. Results: The ...
Dhillon Priyanka - - 2013
We report the case of splenic infarct secondary to embolisation from a polypoid 17mm×10mm thoracic aorta thrombi in a 60 year-old female. The management and prognostic value of thoracic aorta thrombi are poorly defined in literature. This patient was successfully treated with oral anticoagulation as opposed to surgical intervention. Repeat ...
Lauw Mandy N - - 2013
Cerebral venous thrombosis (CVT) is a rare manifestation of venous thromboembolism (VTE) and stroke. The aim of our systematic review was to provide an updated summary of the strength of association between CVT and thrombophilia and to explore the relevance of thrombophilia for recurrence of CVT or other VTE, or ...
Keefe Kelley - - 2013
The use of thrombolytics delivered through an external ventricular drain has improved outcomes in intraventricular hemorrhage, a disease with a poor prognosis; however, presence of an arteriovenous malformation is generally considered a contraindication to thrombolytic use. Due do the high mortality with the current standard of care, thrombolytics should be ...
Kitamura Yohei - - 2013
Isolated cortical vein thrombosis (ICVT) is extremely rare. Only single case or small series of ICVT have been reported; clinical details are still uncertain. We report a case of isolated superficial sylvian vein thrombosis with exceedingly long cord sign. A 14-year-old female with severe sudden onset headache visited our hospital. ...
Gevaert Andreas - - 2013
Heparin-induced thrombocytopenia is a potentiallylife-threatening complication of heparin or low-molecular-weight heparin administration. We describe the case of a patient with heparin-induced thrombocytopenia complicated by pulmonary embolism, successfully treated with fondaparinux, a factor Xa inhibitor. We also review the literature regarding the use of this anticoagulant in heparin-induced thrombocytopenia complicated by ...
Mandanas Stylianos - - 2013
Acute adrenal insufficiency is a potentially lethal condition rarely caused by bilateral adrenal haemorrhage due to heparin use. Most of the times, it is difficult to establish the diagnosis, as symptoms are not specific. Few cases have been reported in the literature. A 52-year-old Caucasian woman presented with abdominal pain, ...
Li Luan - - 2013
Henoch-Schonlein Purpura (HSP) is one of the most common types of vasculitis in children. The characteristic clinical manifestations include non-thrombocytopenic purpura, arthritis or arthralgia, abdominal pain, gastrointestinal hemorrhage and renal abnormalities. Thrombosis has been reported as, a rare complication of HSP. We present the case of a 14-year-old boy who ...
Robert Thomas - - 2013
Background Developmental venous anomaly (DVA) is considered a benign and asymptomatic cerebrovascular malformation, and only isolated cases of symptomatic DVAs are described in the literature. Even more rarely will these symptoms come from an intraparenchymal hemorrhage caused by the DVA.Methods and Results We present two symptomatic DVAs by intracerebellar hemorrhage. ...
Bedogni Alberto - - 2013
In this report, we describe the first successful case of microvascular free tissue transfer in a patient with Evans Syndrome (ES), a rare form of idiopathic thrombocytopenic purpura (ITP) and associated autoimmune hemolytic anemia (AIHA). Microvascular surgery in the setting of ES is likely to have higher complication rates because ...
Lazo-Langner Alejandro - - 2013
New oral anticoagulants, including dabigatran, rivaroxaban, and apixaban, have been recently approved for primary and secondary prophylaxis of thromboembolic conditions. However, there is no clear strategy for managing and reversing their anticoagulant effects. We aimed to summarize the available evidence for clinical management and reversal of bleeding associated with new ...
Badea Radu - - 2013
We present the case of a patient undergoing long-time treatment with oral anticoagulants for a severe vascular pathology who had a major subcapsular liver bleeding as well as retroperitoneal bleeding. The purpose of the paper is to present the specific characteristics of this case, to review the literature that concentrates ...
Hawkins Seth C - - 2013
An increasing number of patients routinely undergo long-term anticoagulation with warfarin or other pharmacological agents. There is little evidence and no consensus documents in the literature regarding the appropriateness and relative risk of their participation in wilderness activities. We present a case report, conduct an analysis of the limited literature ...
Walner David L - - 2013
Postoperative bleeding is a well-recognized complication after tonsillectomy. We believe significant variation exists in how bleeding following tonsillectomy is reported and that a standardized system is needed. Our goal was to develop such a system. Relevant literature was found on Ovid Medline. Studies published from 1996 to 2009 involving post-tonsillectomy ...
Shaw Nick J - - 2013
The first part of this review focused on the skeletal aspects of vitamin D. This second part reviews some of the available evidence that vitamin D may have a physiological extraskeletal role beyond its traditional effect on the skeleton. This aspect has influenced the definition of vitamin D deficiency and ...
Bracard S - - 2013
The most frequent risk in endovascular aneurysm treatment is thromboembolic complications. Thus adjuvant pharmaceuticals are largely focused on preventing and treating these latter. Additionally symptomatic treatment of subarachnoid hemorrhage (SAH) and treatments to avoid vasospasm will enter into play in cases of ruptured aneurisms. Consensus exists in the literature neither ...
Dangle Pankaj P - - 2013
Rectus sheath hematoma (RSH) is uncommon and is often reported in the setting of anticoagulation or trauma. Typically RSH presents with localized or diffuse abdominal pain and a fixed abdominal wall mass, however, various presentations and complications have been reported depending on the setting and extent of the hematoma. We ...
Dharmasena Aruna - - 2013
To report a case of bilateral spontaneous hyphaema in a patient on warfarin sodium for atrial fibrillation and COPD. A case report and literature review. A 76-year-old man presented with bilateral spontaneous hyphaema. There was no anterior chamber pathology known to predispose for spontaneous bleeding except for a history of ...
Marshall Sarah - - 2013
Dabigatran etexilate is a newly approved agent for prophylaxis of stroke in atrial fibrillation. Through narrative review, the authors assess evidence of the efficacy of dabigatran in stroke prevention, focusing on the multicenter, randomized trial RE-LY. The authors complement this with a review of the clinical efficacy of standard treatments ...
Saettele Megan R - - 2013
Congenital anomalies of the inferior vena cava (IVC) are increasingly recognized with CT and venography techniques. Although many patients with IVC anomalies are asymptomatic, recent studies have suggested an association with venous thromboembolism. We report the case of a 62-year-old woman with extensive venous clot involving the infrarenal segment of ...
Avila M L - - 2013
BACKGROUND: Heparin-induced-thrombocytopenia (HIT) has increasingly been reported in children as an indication for use of new alternative anticoagulant drugs (NAADs). OBJECTIVES: To systematically review the literature regarding: a) the incidence and prevalence of seroconversion and HIT and b) the clinical/laboratory findings and management of HIT in children. DESIGN/METHODS: MEDLINE and ...
Hanke A A - - 2013
BACKGROUND: /st>The rapid reversal of the effects of vitamin K antagonists is often required in cases of emergency surgery and life-threatening bleeding, or during bleeding associated with high morbidity and mortality such as intracranial haemorrhage. Increasingly, four-factor prothrombin complex concentrates (PCCs) containing high and well-balanced concentrations of vitamin K-dependent coagulation ...
Boehlen Françoise - - 2013
Less than 60 cases of acquired factor (F)XIII deficiencies have been reported, most having distinct clinical features. To illustrate the therapeutic challenges of acquired FXIII inhibitors, we report a case of a 65-year-old patient with no previous bleeding history who suddenly developed massive haemorrhages associated to a strong and isolated ...
Galanaud J-P - - 2013
Deep-vein thrombosis (DVT) is a common disease. However, unlike varicose veins that have been depicted since antiquity in art and literature, its description was more recent in the history of medicine. The first well-documented case of DVT was reported during the Middle Ages: in 1271 Raoul developed an unilateral edema ...
Gude Dilip - - 2013
Antagonists of vitamin K dependant clotting factors are commonly used as treatment/prophylaxis for anticoagulation. Due to their narrow therapeutic window, a wide range of complications including death may occur. International normalized ratio (INR) is monitored to measure adequacy/excess of anticoagulation. There is a plethora of risk factors that may contribute ...
Costa Fábio Wildson Gurgel - - 2013
To conduct a systematized review of the literature about the main local hemostatic measures to control postoperative bleeding in anticoagulated patients. A systematized review of literature was performed in the electronic database Medline (PubMed) without restriction of the publication date. The eligibility criteria were studies involving maintenance of the anticoagulant ...
Frykberg Robert G - - 2013
Heparin is an anticoagulant commonly used to treat and prevent deep venous thrombosis. Heparin-induced thrombocytopenia and possible thrombosis are serious complications associated with its use. This can occasionally complicate treatment of patients undergoing podiatric surgery. Heparin-induced thrombocytopenia is often not immediately recognized and is underreported in podiatric medicine literature. The ...
Razdan Sheila - - 2013
Although individuals with sickle cell disease (SCD) are at increased risk for stroke, the underlying pathophysiology is incompletely understood. Intracardiac shunting via a patent foramen ovale (PFO) is associated with cryptogenic stroke in individuals without SCD. Recent evidence suggests that PFOs are associated with stroke in children with SCD, although ...
Saifan Chadi - - 2013
Calciphylaxis is a challenging complication of end-stage renal disease, with an unknown underlying mechanism. Several risk factors have been identified, such as hyperphosphatemia, hypercalcemia, hyperparathyroidism, low serum albumin levels, and history of warfarin therapy. This article presents a case of calciphylaxis provoked by reintroduction of warfarin therapy, introducing the possibility ...
Lim Stephanie Hui-Su SH Department of Medical Oncology, Liverpool Hospital, Elizabeth Street, Liverpool, NSW 2170, Australia ; Ingham Institute for Applied Medical Research, Liverpool, NSW 2170, Australia ; University of New South Wales, Kensington, NSW 2033, - - 2013
Takotsubo cardiomyopathy is a rare but increasingly recognized phenomenon, which can occur as a side-effect of chemotherapeutic agents, in particular, the antimetabolite 5-fluorouracil. We describe a case of delayed Takotsubo cardiomyopathy after 3 weeks of adjuvant 5-fluorouracil for resected rectal adenocarcinoma in a 66-year-old female, supported by angiographic, electrocardiographic, and ...
Akins Paul T PT Department of Neurosurgery, Permanente Medical Group, Kaiser Sacramento Medical Center, Sacramento, CA - - 2013
Cerebral venous sinus thrombosis (CVST) can cause elevated intracranial pressure, hemorrhagic venous infarct, and cortical subarachnoid hemorrhage. We present a case series and literature review to illustrate that CVST can also present with subdural hematoma (SDH). Chart review was completed on a retrospective case series of CVST with spontaneous SDH. ...
Busch A A Department of General, Visceral, Vascular and Paediatric Surgery, Julius Maximilians University of Wuerzburg, Oberduerrbacher Street 6, 97080 Wuerzburg, - - 2013
Arterial embolism with lower limb ischemia is a rare manifestation of paraneoplastic hypercoagulability in cancer patients. We report a unique case of fatal thromboembolism involving both circulations associated with a poorly differentiated neuroendocrine tumor of the lung with rapid progress despite high doses of unfractioned heparin and review the current ...
Khan Arif - - 2012
The authors report a case of previously healthy toddler who presented with acute sore throat that led to bacteremia, septic shock, disseminated intravascular coagulopathy, encephalopathy and pleural effusion. Magnetic resonance imaging and venogram showed thrombosis of the internal jugular vein. He was successfully treated with antibiotics and low molecular weight ...
Brown Paula - - 2012
Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening condition that can develop after exposure to unfractionated or low-molecular-weight heparins. Treatment options appear to be limited in patients on concurrent intermittent hemodialysis. We report the case of an 88-year-old man newly initiated on high-flux hemodialysis who developed HIT and extracorporeal circuit thrombosis ...
Lal Yasir - - 2012
ABSTRACT:: Dabigatran etexilate, a direct thrombin inhibitor, has become an alternative to warfarin for stroke prevention in patients with nonvalvular atrial fibrillation. There remains a concern about its overdose and life-threatening hemorrhage because of unavailability of appropriate coagulation tests to monitor and antidotes to reverse its effects. There are no ...
Roberts D C - - 2012
This review summarizes the literature regarding venous thromboembolism and examines the prophylaxis guidelines with relation to hand, wrist and elbow surgery. We performed an extensive literature search identifying any relevant case reports or outcome studies. Of 680 potential articles, only four contained data relevant to thrombosis after elbow, wrist and ...
Mullin Stephen - - 2012
Acute porphyria, though rare, has well-known neurological sequelae. Vasospasm rarely complicates exacerbations of acute intermittent porphyria, but has not been previously reported in hereditary coproporphyria. We describe a porphyric crisis in a woman with previously undiagnosed hereditary coproporphyria (triggered by rifampicin), leading to vasospasm and stroke.
Au Joshua K - - 2012
OBJECTIVES: A case of pediatric otogenic lateral sinus thrombosis is reported, followed by a substantive literature review. DESIGN: 104 patients were reviewed, culled from published case reports from 1993 to 2011 on the PubMed database. METHODS: All full text case reports on the PubMed database from 1993 to 2011 with ...
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